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The map label for this gene is cbiL [H]

Identifier: 28210456

GI number: 28210456

Start: 761774

End: 762439

Strand: Direct

Name: cbiL [H]

Synonym: CTC00735

Alternate gene names: 28210456

Gene position: 761774-762439 (Clockwise)

Preceding gene: 28210455

Following gene: 28210457

Centisome position: 27.21

GC content: 28.08

Gene sequence:

>666_bases
ATGGCTAAATTATATGGAATAGGTGTAGGACCAGGAAGTGAAGAACTTTTAACAGTAAAAGCTGTTAATATATTGAAAAA
TGCAAAGGTAGTTATTGCTCCATCTTCAAAAAATGGAGGAGACAGTATAGCACTACAAGCTTGTGAAAAATACATAAATA
AAGATGCAGAAAAAATAGTAAAACATTTTCCAATGGGGAAATCAGATAGGGAAGAAAAAATATACAATGCTTTTAAAACT
ATAGAAGAATATTTACAAAAGGACCAGGATGTAGTTTTTCTAACTATAGGAGATCCTTTTGTATATAGCACTTATATATA
TCTTCTAGAACATATAAATGAAAAGGGATATGAAACAGAAACAGTGCCAGGTATAACTTCCTTTTGTGCTGCTGCAAGCT
TAGCAGGAGAGGAATTAGTAATAGGAGATGAACCATTATTAATATTACCTTCTACTAGATTAGATAGTATAAAAGATGAA
AAATATGTAGTTATAATGAAACTATATAATAATGAAGAAAAAGTTTTAAACTTTTTAGAAGAAAGAAATTTTAAATATAT
ATGTGTAAGAAGGGCTTATAGAGAAGGACAACAAATACTTAGAAATAGAGAAGAAATAATAGAAAATAAAGATTATATGT
CTCTTATAATTGCAAATAGAGAGTAA

Upstream 100 bases:

>100_bases
AAGGTAAAGTGTACTCAAGTGTCCATAAGTAAGACTAGAGGGCAAACTTATATGTTAATGGGATATAATCCAATATTTAT
AATAGAAGGAGAAAAGACAA

Downstream 100 bases:

>100_bases
AGAAAGGAAGATATAGTATGAGTAAAATTGCTTCAAAAGTATATTTCATAGGTGCAGGACCTGGAGATGTGGATTTAATT
ACAGTAAAAGGAAGAGATAT

Product: cobalt-precorrin-2 C(20)-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--cobalt-precorrin-2 methyltransferase [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MAKLYGIGVGPGSEELLTVKAVNILKNAKVVIAPSSKNGGDSIALQACEKYINKDAEKIVKHFPMGKSDREEKIYNAFKT
IEEYLQKDQDVVFLTIGDPFVYSTYIYLLEHINEKGYETETVPGITSFCAAASLAGEELVIGDEPLLILPSTRLDSIKDE
KYVVIMKLYNNEEKVLNFLEERNFKYICVRRAYREGQQILRNREEIIENKDYMSLIIANRE

Sequences:

>Translated_221_residues
MAKLYGIGVGPGSEELLTVKAVNILKNAKVVIAPSSKNGGDSIALQACEKYINKDAEKIVKHFPMGKSDREEKIYNAFKT
IEEYLQKDQDVVFLTIGDPFVYSTYIYLLEHINEKGYETETVPGITSFCAAASLAGEELVIGDEPLLILPSTRLDSIKDE
KYVVIMKLYNNEEKVLNFLEERNFKYICVRRAYREGQQILRNREEIIENKDYMSLIIANRE
>Mature_220_residues
AKLYGIGVGPGSEELLTVKAVNILKNAKVVIAPSSKNGGDSIALQACEKYINKDAEKIVKHFPMGKSDREEKIYNAFKTI
EEYLQKDQDVVFLTIGDPFVYSTYIYLLEHINEKGYETETVPGITSFCAAASLAGEELVIGDEPLLILPSTRLDSIKDEK
YVVIMKLYNNEEKVLNFLEERNFKYICVRRAYREGQQILRNREEIIENKDYMSLIIANRE

Specific function: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.151 [H]

Molecular weight: Translated: 25173; Mature: 25042

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLYGIGVGPGSEELLTVKAVNILKNAKVVIAPSSKNGGDSIALQACEKYINKDAEKIV
CCEEEEEECCCCCCCEEEHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHH
KHFPMGKSDREEKIYNAFKTIEEYLQKDQDVVFLTIGDPFVYSTYIYLLEHINEKGYETE
HHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCC
TVPGITSFCAAASLAGEELVIGDEPLLILPSTRLDSIKDEKYVVIMKLYNNEEKVLNFLE
CCCCHHHHHHHHHCCCCEEEECCCCEEEECCCCCCCCCCCCEEEEEEEECCHHHHHHHHH
ERNFKYICVRRAYREGQQILRNREEIIENKDYMSLIIANRE
HCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
>Mature Secondary Structure 
AKLYGIGVGPGSEELLTVKAVNILKNAKVVIAPSSKNGGDSIALQACEKYINKDAEKIV
CEEEEEECCCCCCCEEEHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHH
KHFPMGKSDREEKIYNAFKTIEEYLQKDQDVVFLTIGDPFVYSTYIYLLEHINEKGYETE
HHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCC
TVPGITSFCAAASLAGEELVIGDEPLLILPSTRLDSIKDEKYVVIMKLYNNEEKVLNFLE
CCCCHHHHHHHHHCCCCEEEECCCCEEEECCCCCCCCCCCCEEEEEEEECCHHHHHHHHH
ERNFKYICVRRAYREGQQILRNREEIIENKDYMSLIIANRE
HCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609 [H]