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The map label for this gene is 28210447

Identifier: 28210447

GI number: 28210447

Start: 752229

End: 752960

Strand: Direct

Name: 28210447

Synonym: CTC00726

Alternate gene names: NA

Gene position: 752229-752960 (Clockwise)

Preceding gene: 28210446

Following gene: 161486849

Centisome position: 26.87

GC content: 26.64

Gene sequence:

>732_bases
GTGCTTGAGAATAATAGAAAAGATATTTTACTCCGCCCAATAGAATATTCTTTTATATCCTTACTATCTAATAAAATAAA
AGTATTAATAGTAGGTGGAGGAAGAGCAGGTTTTATAAAAGCTAAGACTCTTAGTAATAATGGATGTAGGGTAAAAGTAA
TAAGCAAAAATTTCTCAAAAGAATTTGAGGAATTAAAAAAGCTTTCCAATGTGCAATTAATAAAAGATGAATATAAAAAG
GATTATATATCAGAAAATCATCTAATAATAATTGCAGTTGAAGATGAGACCACTAATGAAATTATAAGGAAGCATTGTGA
TGAACAATGCAAACTATATTTGGATTGTTCACATTTTGAAAGAGGACTTTTTGTAGTACCTTGTCAAAGAAGTAGTAAAA
CAGCAACTTTTGGTATAAATACTAAAGGTGGAAGCCCAAAGACTGCTATATATTTAGCAGAGGAAATAAAGGATAATTTA
ATAAAAAAAGATTCCTTTATAGAATATAGTTATAAATTAAGAAATATCATAAATAAATCTGAAGATAAGGCTACTATAAT
GGATTTTGTAGCCACAGAGGATTTTTACTTTTTTTACAATAAAAATAAGCACAAAATTATATTAGAAATGTTTTTTGGAG
GTAATTATTTTGAAGTTAATAGTAGCCACAAGAAGGAGTATTTTAGCACAAACTCAAACAGATTTAGTAATAAAGAAAAT
AGAGGAAGATAA

Upstream 100 bases:

>100_bases
ACGCTTTAGCAGAAATTATGCTCAAAAGTACATCTAATGCGTATATAAATAAGGCTATTGAAGTATTAAAAGAAGAACAG
TTGAAGGGAAGAGGAGAGGA

Downstream 100 bases:

>100_bases
TGAGGTAAAATGTGAAAAACTTTTAATTCAAACTCTAGGGGATAAAATATTAGATAGAACCCTAGATAAAATAGGAGGGA
AGGGACTATTTATAAAAGAA

Product: precorrin-2 dehydrogenase

Products: sirohydrochlorin; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MLENNRKDILLRPIEYSFISLLSNKIKVLIVGGGRAGFIKAKTLSNNGCRVKVISKNFSKEFEELKKLSNVQLIKDEYKK
DYISENHLIIIAVEDETTNEIIRKHCDEQCKLYLDCSHFERGLFVVPCQRSSKTATFGINTKGGSPKTAIYLAEEIKDNL
IKKDSFIEYSYKLRNIINKSEDKATIMDFVATEDFYFFYNKNKHKIILEMFFGGNYFEVNSSHKKEYFSTNSNRFSNKEN
RGR

Sequences:

>Translated_243_residues
MLENNRKDILLRPIEYSFISLLSNKIKVLIVGGGRAGFIKAKTLSNNGCRVKVISKNFSKEFEELKKLSNVQLIKDEYKK
DYISENHLIIIAVEDETTNEIIRKHCDEQCKLYLDCSHFERGLFVVPCQRSSKTATFGINTKGGSPKTAIYLAEEIKDNL
IKKDSFIEYSYKLRNIINKSEDKATIMDFVATEDFYFFYNKNKHKIILEMFFGGNYFEVNSSHKKEYFSTNSNRFSNKEN
RGR
>Mature_243_residues
MLENNRKDILLRPIEYSFISLLSNKIKVLIVGGGRAGFIKAKTLSNNGCRVKVISKNFSKEFEELKKLSNVQLIKDEYKK
DYISENHLIIIAVEDETTNEIIRKHCDEQCKLYLDCSHFERGLFVVPCQRSSKTATFGINTKGGSPKTAIYLAEEIKDNL
IKKDSFIEYSYKLRNIINKSEDKATIMDFVATEDFYFFYNKNKHKIILEMFFGGNYFEVNSSHKKEYFSTNSNRFSNKEN
RGR

Specific function: Unknown

COG id: COG1648

COG function: function code H; Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.3.1.76; 4.99.1.4

Molecular weight: Translated: 28273; Mature: 28273

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLENNRKDILLRPIEYSFISLLSNKIKVLIVGGGRAGFIKAKTLSNNGCRVKVISKNFSK
CCCCCCCCEEEECCHHHHHHHHCCCEEEEEEECCCCCEEEEEEECCCCCEEEEECCHHHH
EFEELKKLSNVQLIKDEYKKDYISENHLIIIAVEDETTNEIIRKHCDEQCKLYLDCSHFE
HHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCCEEEEEEECCCC
RGLFVVPCQRSSKTATFGINTKGGSPKTAIYLAEEIKDNLIKKDSFIEYSYKLRNIINKS
CCEEEEECCCCCCEEEEEEECCCCCCCEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHCCC
EDKATIMDFVATEDFYFFYNKNKHKIILEMFFGGNYFEVNSSHKKEYFSTNSNRFSNKEN
CCHHHHHHHHCCCCEEEEEECCCCEEEEEEEECCCEEEECCCCCHHHHCCCCCCCCCCCC
RGR
CCC
>Mature Secondary Structure
MLENNRKDILLRPIEYSFISLLSNKIKVLIVGGGRAGFIKAKTLSNNGCRVKVISKNFSK
CCCCCCCCEEEECCHHHHHHHHCCCEEEEEEECCCCCEEEEEEECCCCCEEEEECCHHHH
EFEELKKLSNVQLIKDEYKKDYISENHLIIIAVEDETTNEIIRKHCDEQCKLYLDCSHFE
HHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCCEEEEEEECCCC
RGLFVVPCQRSSKTATFGINTKGGSPKTAIYLAEEIKDNLIKKDSFIEYSYKLRNIINKS
CCEEEEECCCCCCEEEEEEECCCCCCCEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHCCC
EDKATIMDFVATEDFYFFYNKNKHKIILEMFFGGNYFEVNSSHKKEYFSTNSNRFSNKEN
CCHHHHHHHHCCCCEEEEEECCCCEEEEEEEECCCEEEECCCCCHHHHCCCCCCCCCCCC
RGR
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 2; NAD+

Specific reaction: precorrin-2 + NAD+ = sirohydrochlorin + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA