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The map label for this gene is fixA [H]

Identifier: 28210433

GI number: 28210433

Start: 734977

End: 735756

Strand: Direct

Name: fixA [H]

Synonym: CTC00711

Alternate gene names: 28210433

Gene position: 734977-735756 (Clockwise)

Preceding gene: 28210432

Following gene: 28210434

Centisome position: 26.26

GC content: 35.13

Gene sequence:

>780_bases
ATGAATATAGTTGTTTGCGTAAAGCAAGTTCCAGATACTACAGAAGTTAAAATAGATCCAGTAACAGGAACACTTATAAG
AGAAGGTGTTCCATCAATAATGAACCCAGATGATAAAAATGCCCTAGAAGAAGCTTTAAGATTAAAAGAAAGCAATGGTG
CTAAGGTAACAGTAATAACAATGGGACCACAACAAGCAGAATCAACTCTAAGAGAAGCATTATCAATGGGAGCAGATGAA
GCAATATTAATATCAGATAGAGCTTTTGCAGGTGCAGATACATTAGCAACAGCAACAGCATTAAGTGCAGCTATTAAAAA
GCTAGACTACGATATAGTATTTGCTGGAAGACAAGCTATAGATGGAGATACAGCGCAAGTTGGACCAGAAATAGCAGAAA
ACTTAGACTTACCTCAAATTACTTATGTAGAAAAAGTTGAAGTAGATGGAGAAGAATTAAAAGTTAGAAGAGCTTGGGAA
GATGGATACGAAAATATAAGAGTTAAAACACCAGTTCTTTTAACAGCAATAAAAGAACTTAATGAACCAAGATATATGCA
CGTAGCTCATATATTTGGAGCGTTTGATAAAGAAATAAAAACTTGGAATGCAGACTTTTTAGAAGTAGATAAATCCCTTC
TTGGACTAAGAGGATCTCCAACAAAAGTTAAGAGATCAACAACAAAAGAAGCAAAGGGAAAAGGCGAAGTTATAAGCCTA
ACTCCAAAGGAAGCAGCACAATGTGCAGTAGCAAAACTAAAGGAAAAGCACTACATCTAA

Upstream 100 bases:

>100_bases
TGAGAGATGCTAAGATAACTGAAATCTATGAAGGAACTTCACAAGTTCAACAAATGGTTATTTCAGGAAGCTTATTTAGA
TAATAAGGAGGTTAAAATAC

Downstream 100 bases:

>100_bases
TAAAATAGGAGGGATAAAGAATGAATATAGCAGATTACAAAGGTGTTTGGGTATTCGCTGAACAAAGAGATGGCGAACTT
CAAAAAGTTTCACTTGAACT

Product: electron transfer flavoprotein beta subunit fixA

Products: NA

Alternate protein names: Beta-ETF; Electron transfer flavoprotein small subunit; ETFSS [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MNIVVCVKQVPDTTEVKIDPVTGTLIREGVPSIMNPDDKNALEEALRLKESNGAKVTVITMGPQQAESTLREALSMGADE
AILISDRAFAGADTLATATALSAAIKKLDYDIVFAGRQAIDGDTAQVGPEIAENLDLPQITYVEKVEVDGEELKVRRAWE
DGYENIRVKTPVLLTAIKELNEPRYMHVAHIFGAFDKEIKTWNADFLEVDKSLLGLRGSPTKVKRSTTKEAKGKGEVISL
TPKEAAQCAVAKLKEKHYI

Sequences:

>Translated_259_residues
MNIVVCVKQVPDTTEVKIDPVTGTLIREGVPSIMNPDDKNALEEALRLKESNGAKVTVITMGPQQAESTLREALSMGADE
AILISDRAFAGADTLATATALSAAIKKLDYDIVFAGRQAIDGDTAQVGPEIAENLDLPQITYVEKVEVDGEELKVRRAWE
DGYENIRVKTPVLLTAIKELNEPRYMHVAHIFGAFDKEIKTWNADFLEVDKSLLGLRGSPTKVKRSTTKEAKGKGEVISL
TPKEAAQCAVAKLKEKHYI
>Mature_259_residues
MNIVVCVKQVPDTTEVKIDPVTGTLIREGVPSIMNPDDKNALEEALRLKESNGAKVTVITMGPQQAESTLREALSMGADE
AILISDRAFAGADTLATATALSAAIKKLDYDIVFAGRQAIDGDTAQVGPEIAENLDLPQITYVEKVEVDGEELKVRRAWE
DGYENIRVKTPVLLTAIKELNEPRYMHVAHIFGAFDKEIKTWNADFLEVDKSLLGLRGSPTKVKRSTTKEAKGKGEVISL
TPKEAAQCAVAKLKEKHYI

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2086

COG function: function code C; Electron transfer flavoprotein, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF beta-subunit/fixA family [H]

Homologues:

Organism=Homo sapiens, GI4503609, Length=215, Percent_Identity=37.6744186046512, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI62420877, Length=200, Percent_Identity=38, Blast_Score=117, Evalue=7e-27,
Organism=Escherichia coli, GI2367123, Length=227, Percent_Identity=29.9559471365639, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87081682, Length=208, Percent_Identity=29.8076923076923, Blast_Score=81, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI25141345, Length=264, Percent_Identity=34.8484848484849, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6321646, Length=220, Percent_Identity=34.0909090909091, Blast_Score=96, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24651147, Length=216, Percent_Identity=36.1111111111111, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24651145, Length=216, Percent_Identity=36.1111111111111, Blast_Score=103, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000049
- InterPro:   IPR014730
- InterPro:   IPR012255
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF [H]

EC number: NA

Molecular weight: Translated: 28289; Mature: 28289

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS01065 ETF_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIVVCVKQVPDTTEVKIDPVTGTLIREGVPSIMNPDDKNALEEALRLKESNGAKVTVIT
CCEEEEEECCCCCCEEEEECCCHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEE
MGPQQAESTLREALSMGADEAILISDRAFAGADTLATATALSAAIKKLDYDIVFAGRQAI
ECHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCC
DGDTAQVGPEIAENLDLPQITYVEKVEVDGEELKVRRAWEDGYENIRVKTPVLLTAIKEL
CCCHHHCCHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHC
NEPRYMHVAHIFGAFDKEIKTWNADFLEVDKSLLGLRGSPTKVKRSTTKEAKGKGEVISL
CCCCEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEE
TPKEAAQCAVAKLKEKHYI
CHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIVVCVKQVPDTTEVKIDPVTGTLIREGVPSIMNPDDKNALEEALRLKESNGAKVTVIT
CCEEEEEECCCCCCEEEEECCCHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEE
MGPQQAESTLREALSMGADEAILISDRAFAGADTLATATALSAAIKKLDYDIVFAGRQAI
ECHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCC
DGDTAQVGPEIAENLDLPQITYVEKVEVDGEELKVRRAWEDGYENIRVKTPVLLTAIKEL
CCCHHHCCHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHC
NEPRYMHVAHIFGAFDKEIKTWNADFLEVDKSLLGLRGSPTKVKRSTTKEAKGKGEVISL
CCCCEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEE
TPKEAAQCAVAKLKEKHYI
CHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]