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The map label for this gene is fixB [H]

Identifier: 28210434

GI number: 28210434

Start: 735777

End: 736787

Strand: Direct

Name: fixB [H]

Synonym: CTC00712

Alternate gene names: 28210434

Gene position: 735777-736787 (Clockwise)

Preceding gene: 28210433

Following gene: 28210435

Centisome position: 26.28

GC content: 34.82

Gene sequence:

>1011_bases
ATGAATATAGCAGATTACAAAGGTGTTTGGGTATTCGCTGAACAAAGAGATGGCGAACTTCAAAAAGTTTCACTTGAACT
TTTAGGAAAAGGAAGAGAAATTGCAGACAAACTAGGAGTAGAGTTAACAGCTCTTCTTTTAGGAAATAAAATAGATAGCA
TAGCAGAAGAATTAGTAGCATATGGAGCTGACAAAGTAATATATGCACAAAATCCACTACTAAGTCACTATACAACAGAC
GGATATACAAAAGTTATATGTGATCTTGTAGCTGAAGAAAAACCTGAAATAATTCTTGTAGGGGCAACATATATAGGAAG
AGATTTAGGACCAAGAGTTGCAGCAAGACTAAGAACAGGACTTACAGCAGATTGTACAGCACTTGACGTAGAAGAAGGAA
CTAACAATCTACTAATGACAAGACCAGCTTTTGGTGGAAATCTTATGGCCACAATAGTTTGTGGAGAACATAGACCACAA
ATGTCTACAGTTAGACCTGGGGTTTTTGAAAAACTTAAAAAGGATGCAGGAAGAAAAGGCGAAATCAAAAAGATAGAAGC
TAAATTAGAAATGTCAGATATAAGAACAAAGGTAGAAGACGTTGTAAAAATAACTAAGAATGTTATGGATATAGGAGAAG
CTGAATTCCTAGTAGCAGGTGGTAGAGGAATAGGTTCAAAAGAAAACTTTAAAATGTTAGAAGAACTTGCAGAACTTCTT
GGGGGAAATGTAGCAGGATCAAGAGCTGCTATAGACAACGGATGGATAGATAAAGATTACCAAGTAGGACAAACAGGAAA
AACTGTAAGACCAATGGTTTATATAGCAGTAGGTATATCTGGAGCAATCCAACATTTAGCTGGAATGCAAGACTCAGATT
ATATAATTGCTATAAATAAAGATGAAGCAGCTCCAATAATGCAAATTGCTGATTTAGGATTAGTTGGGGATTATAACAAA
ATAGTACCTGAATTAATAGCTAAGTTAAAGGAAGAAAAAGAAGAAAATTAA

Upstream 100 bases:

>100_bases
AAGGCGAAGTTATAAGCCTAACTCCAAAGGAAGCAGCACAATGTGCAGTAGCAAAACTAAAGGAAAAGCACTACATCTAA
TAAAATAGGAGGGATAAAGA

Downstream 100 bases:

>100_bases
AGTAAATGACCTCTTTAAAAGGGGTCATTTTTATATATAATTGTTAGTTGTGGTAAAATACATGTAAAGAGTTTTTAAAG
GGGTGCAAGAATTATGAAGT

Product: electron transfer flavoprotein alpha-subunit fixB

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MNIADYKGVWVFAEQRDGELQKVSLELLGKGREIADKLGVELTALLLGNKIDSIAEELVAYGADKVIYAQNPLLSHYTTD
GYTKVICDLVAEEKPEIILVGATYIGRDLGPRVAARLRTGLTADCTALDVEEGTNNLLMTRPAFGGNLMATIVCGEHRPQ
MSTVRPGVFEKLKKDAGRKGEIKKIEAKLEMSDIRTKVEDVVKITKNVMDIGEAEFLVAGGRGIGSKENFKMLEELAELL
GGNVAGSRAAIDNGWIDKDYQVGQTGKTVRPMVYIAVGISGAIQHLAGMQDSDYIIAINKDEAAPIMQIADLGLVGDYNK
IVPELIAKLKEEKEEN

Sequences:

>Translated_336_residues
MNIADYKGVWVFAEQRDGELQKVSLELLGKGREIADKLGVELTALLLGNKIDSIAEELVAYGADKVIYAQNPLLSHYTTD
GYTKVICDLVAEEKPEIILVGATYIGRDLGPRVAARLRTGLTADCTALDVEEGTNNLLMTRPAFGGNLMATIVCGEHRPQ
MSTVRPGVFEKLKKDAGRKGEIKKIEAKLEMSDIRTKVEDVVKITKNVMDIGEAEFLVAGGRGIGSKENFKMLEELAELL
GGNVAGSRAAIDNGWIDKDYQVGQTGKTVRPMVYIAVGISGAIQHLAGMQDSDYIIAINKDEAAPIMQIADLGLVGDYNK
IVPELIAKLKEEKEEN
>Mature_336_residues
MNIADYKGVWVFAEQRDGELQKVSLELLGKGREIADKLGVELTALLLGNKIDSIAEELVAYGADKVIYAQNPLLSHYTTD
GYTKVICDLVAEEKPEIILVGATYIGRDLGPRVAARLRTGLTADCTALDVEEGTNNLLMTRPAFGGNLMATIVCGEHRPQ
MSTVRPGVFEKLKKDAGRKGEIKKIEAKLEMSDIRTKVEDVVKITKNVMDIGEAEFLVAGGRGIGSKENFKMLEELAELL
GGNVAGSRAAIDNGWIDKDYQVGQTGKTVRPMVYIAVGISGAIQHLAGMQDSDYIIAINKDEAAPIMQIADLGLVGDYNK
IVPELIAKLKEEKEEN

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=330, Percent_Identity=36.969696969697, Blast_Score=188, Evalue=6e-48,
Organism=Homo sapiens, GI189181759, Length=283, Percent_Identity=38.5159010600707, Blast_Score=169, Evalue=3e-42,
Organism=Escherichia coli, GI1786226, Length=331, Percent_Identity=30.8157099697885, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1787990, Length=347, Percent_Identity=29.6829971181556, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI87082157, Length=240, Percent_Identity=27.5, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17506929, Length=332, Percent_Identity=36.4457831325301, Blast_Score=179, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6325261, Length=335, Percent_Identity=32.2388059701493, Blast_Score=155, Evalue=8e-39,
Organism=Drosophila melanogaster, GI17136898, Length=327, Percent_Identity=37.0030581039755, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24652801, Length=327, Percent_Identity=37.0030581039755, Blast_Score=182, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 36508; Mature: 36508

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIADYKGVWVFAEQRDGELQKVSLELLGKGREIADKLGVELTALLLGNKIDSIAEELVA
CCCCCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHHCHHHEEHHHCCHHHHHHHHHHH
YGADKVIYAQNPLLSHYTTDGYTKVICDLVAEEKPEIILVGATYIGRDLGPRVAARLRTG
HCCCEEEEECCCCHHHCCCCCHHHHHHHHHHCCCCCEEEEECHHHCCCCCHHHHHHHHCC
LTADCTALDVEEGTNNLLMTRPAFGGNLMATIVCGEHRPQMSTVRPGVFEKLKKDAGRKG
CCCCCEEEECCCCCCCEEEECCCCCCCEEEEEEECCCCCCCHHCCCHHHHHHHHHCCCCC
EIKKIEAKLEMSDIRTKVEDVVKITKNVMDIGEAEFLVAGGRGIGSKENFKMLEELAELL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
GGNVAGSRAAIDNGWIDKDYQVGQTGKTVRPMVYIAVGISGAIQHLAGMQDSDYIIAINK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCCCCCEEEEECC
DEAAPIMQIADLGLVGDYNKIVPELIAKLKEEKEEN
CCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIADYKGVWVFAEQRDGELQKVSLELLGKGREIADKLGVELTALLLGNKIDSIAEELVA
CCCCCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHHCHHHEEHHHCCHHHHHHHHHHH
YGADKVIYAQNPLLSHYTTDGYTKVICDLVAEEKPEIILVGATYIGRDLGPRVAARLRTG
HCCCEEEEECCCCHHHCCCCCHHHHHHHHHHCCCCCEEEEECHHHCCCCCHHHHHHHHCC
LTADCTALDVEEGTNNLLMTRPAFGGNLMATIVCGEHRPQMSTVRPGVFEKLKKDAGRKG
CCCCCEEEECCCCCCCEEEECCCCCCCEEEEEEECCCCCCCHHCCCHHHHHHHHHCCCCC
EIKKIEAKLEMSDIRTKVEDVVKITKNVMDIGEAEFLVAGGRGIGSKENFKMLEELAELL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
GGNVAGSRAAIDNGWIDKDYQVGQTGKTVRPMVYIAVGISGAIQHLAGMQDSDYIIAINK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCCCCCEEEEECC
DEAAPIMQIADLGLVGDYNKIVPELIAKLKEEKEEN
CCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]