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The map label for this gene is bcd [H]

Identifier: 28210432

GI number: 28210432

Start: 733820

End: 734959

Strand: Direct

Name: bcd [H]

Synonym: CTC00710

Alternate gene names: 28210432

Gene position: 733820-734959 (Clockwise)

Preceding gene: 28210431

Following gene: 28210433

Centisome position: 26.21

GC content: 34.65

Gene sequence:

>1140_bases
ATGAATTTTGCATTAACTAGAGAACAAGAATTTGTAAGACAAATGGTAAGAGAGTTTGCTGAAACAGAAGTAAAGCCAAT
TGCCGCAGAAATTGATGAAACAGAAAGATTTCCTATGGAAAACGTAGAAAAGATGGCTAAACTTGGTATGATGGGTATTC
CAATACCAAAAGAATATGGTGGAGCAGGTGGAGATGTATTATCCTACATCATAGCTGTAGAAGAATTATCAAAAGTATGT
GGAACAACAGGAGTTATAGTATCAGCACATACATCTCTTTGTGCAAGCTTAATATATGAACATGGAACAGAAGAACAAAA
ACAAAAATATCTAATTCCATTAGCAAAAGGAGAAAAAATAGGGGCTTTTGGATTAACAGAACCTAATGCAGGAACAGATG
CAGCAGGACAACAAAGTGTAGCAATAGATATGGGAGACCACTATTTATTAAATGGATCAAAAATATTCATAACAAATGGT
GGAGTTGCAGATGTAGCTGTAGTATTTGCTATGACTGATAGAAGTAAAGGAACTAGGGGAATATCAGCATTCATACTTGA
AAAAGGAATGCCAGGATTCTCAGTAGGAAAAGTAGAAGATAAAATGGGTATAAGAGCATCTTCAACAACAGAACTTATTT
TTGAAGATGTAAAAGTACCAAAGGAAAACTTAATAGGAAAAGAAGGAAGAGGCTTTGGAATTGCTATGAAAACTCTAGAT
GGAGGAAGAATAGGAATAGCATCTCAAGCTTTAGGAATAGCAGAAGGTGCCCTAGAAGAAGCTATAACATATATGAAAGA
AAGAAAACAATTTGGAAGAGAACTTTATAAATTCCAAGGATTATCTTGGATGATGGCAGACATGAAAGTAGCAATAGAAA
GTGCAAGACTTTTAGTTTACCAAGCAGCATGGAAAAAGCAAAATAAACTACCATACTCAGAGGAAGCTGCAATGGCAAAA
CTACATGCGGCTAACGTTGCTATGGATGTAACAACTAAAGTTGTTCAATTGTTTGGAGGATATGGATATACAAAAGATTA
TCCAGTAGAAAGAATGATGAGAGATGCTAAGATAACTGAAATCTATGAAGGAACTTCACAAGTTCAACAAATGGTTATTT
CAGGAAGCTTATTTAGATAA

Upstream 100 bases:

>100_bases
TGTTATGGGAGTAGTTTAATATAAATCACTTTAATAAAGTTAGTTATTTAACAAACAAGATGTTTTATTAATATAAATAT
TTAATAGGAGGTAAGAATAA

Downstream 100 bases:

>100_bases
TAAGGAGGTTAAAATACATGAATATAGTTGTTTGCGTAAAGCAAGTTCCAGATACTACAGAAGTTAAAATAGATCCAGTA
ACAGGAACACTTATAAGAGA

Product: acyl-CoA/butyryl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MNFALTREQEFVRQMVREFAETEVKPIAAEIDETERFPMENVEKMAKLGMMGIPIPKEYGGAGGDVLSYIIAVEELSKVC
GTTGVIVSAHTSLCASLIYEHGTEEQKQKYLIPLAKGEKIGAFGLTEPNAGTDAAGQQSVAIDMGDHYLLNGSKIFITNG
GVADVAVVFAMTDRSKGTRGISAFILEKGMPGFSVGKVEDKMGIRASSTTELIFEDVKVPKENLIGKEGRGFGIAMKTLD
GGRIGIASQALGIAEGALEEAITYMKERKQFGRELYKFQGLSWMMADMKVAIESARLLVYQAAWKKQNKLPYSEEAAMAK
LHAANVAMDVTTKVVQLFGGYGYTKDYPVERMMRDAKITEIYEGTSQVQQMVISGSLFR

Sequences:

>Translated_379_residues
MNFALTREQEFVRQMVREFAETEVKPIAAEIDETERFPMENVEKMAKLGMMGIPIPKEYGGAGGDVLSYIIAVEELSKVC
GTTGVIVSAHTSLCASLIYEHGTEEQKQKYLIPLAKGEKIGAFGLTEPNAGTDAAGQQSVAIDMGDHYLLNGSKIFITNG
GVADVAVVFAMTDRSKGTRGISAFILEKGMPGFSVGKVEDKMGIRASSTTELIFEDVKVPKENLIGKEGRGFGIAMKTLD
GGRIGIASQALGIAEGALEEAITYMKERKQFGRELYKFQGLSWMMADMKVAIESARLLVYQAAWKKQNKLPYSEEAAMAK
LHAANVAMDVTTKVVQLFGGYGYTKDYPVERMMRDAKITEIYEGTSQVQQMVISGSLFR
>Mature_379_residues
MNFALTREQEFVRQMVREFAETEVKPIAAEIDETERFPMENVEKMAKLGMMGIPIPKEYGGAGGDVLSYIIAVEELSKVC
GTTGVIVSAHTSLCASLIYEHGTEEQKQKYLIPLAKGEKIGAFGLTEPNAGTDAAGQQSVAIDMGDHYLLNGSKIFITNG
GVADVAVVFAMTDRSKGTRGISAFILEKGMPGFSVGKVEDKMGIRASSTTELIFEDVKVPKENLIGKEGRGFGIAMKTLD
GGRIGIASQALGIAEGALEEAITYMKERKQFGRELYKFQGLSWMMADMKVAIESARLLVYQAAWKKQNKLPYSEEAAMAK
LHAANVAMDVTTKVVQLFGGYGYTKDYPVERMMRDAKITEIYEGTSQVQQMVISGSLFR

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=375, Percent_Identity=49.8666666666667, Blast_Score=384, Evalue=1e-107,
Organism=Homo sapiens, GI4501859, Length=370, Percent_Identity=42.1621621621622, Blast_Score=317, Evalue=2e-86,
Organism=Homo sapiens, GI226958412, Length=373, Percent_Identity=40.7506702412869, Blast_Score=291, Evalue=5e-79,
Organism=Homo sapiens, GI226958414, Length=333, Percent_Identity=41.7417417417417, Blast_Score=274, Evalue=1e-73,
Organism=Homo sapiens, GI7656849, Length=376, Percent_Identity=40.1595744680851, Blast_Score=273, Evalue=1e-73,
Organism=Homo sapiens, GI4557231, Length=378, Percent_Identity=38.6243386243386, Blast_Score=269, Evalue=3e-72,
Organism=Homo sapiens, GI187960098, Length=378, Percent_Identity=38.6243386243386, Blast_Score=269, Evalue=3e-72,
Organism=Homo sapiens, GI21361497, Length=369, Percent_Identity=40.650406504065, Blast_Score=245, Evalue=6e-65,
Organism=Homo sapiens, GI4501857, Length=372, Percent_Identity=36.0215053763441, Blast_Score=236, Evalue=3e-62,
Organism=Homo sapiens, GI76496475, Length=384, Percent_Identity=35.6770833333333, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI4557235, Length=384, Percent_Identity=35.6770833333333, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI4503943, Length=371, Percent_Identity=32.8840970350404, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI7669494, Length=361, Percent_Identity=33.2409972299169, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI48976061, Length=396, Percent_Identity=29.5454545454545, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI211971008, Length=396, Percent_Identity=29.5454545454545, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI38505218, Length=397, Percent_Identity=26.1964735516373, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI218563752, Length=228, Percent_Identity=28.9473684210526, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1786223, Length=380, Percent_Identity=28.9473684210526, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI87081958, Length=371, Percent_Identity=28.8409703504043, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI87081702, Length=246, Percent_Identity=28.4552845528455, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87082384, Length=280, Percent_Identity=23.2142857142857, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508101, Length=370, Percent_Identity=44.0540540540541, Blast_Score=323, Evalue=6e-89,
Organism=Caenorhabditis elegans, GI17506239, Length=370, Percent_Identity=42.1621621621622, Blast_Score=314, Evalue=4e-86,
Organism=Caenorhabditis elegans, GI17534899, Length=382, Percent_Identity=41.3612565445026, Blast_Score=284, Evalue=5e-77,
Organism=Caenorhabditis elegans, GI17569725, Length=382, Percent_Identity=41.6230366492147, Blast_Score=283, Evalue=9e-77,
Organism=Caenorhabditis elegans, GI17570075, Length=381, Percent_Identity=39.1076115485564, Blast_Score=274, Evalue=7e-74,
Organism=Caenorhabditis elegans, GI17533517, Length=376, Percent_Identity=39.3617021276596, Blast_Score=273, Evalue=9e-74,
Organism=Caenorhabditis elegans, GI17538396, Length=377, Percent_Identity=37.4005305039788, Blast_Score=270, Evalue=8e-73,
Organism=Caenorhabditis elegans, GI71990804, Length=276, Percent_Identity=45.2898550724638, Blast_Score=256, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI71985184, Length=352, Percent_Identity=36.6477272727273, Blast_Score=218, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI17534353, Length=371, Percent_Identity=34.7708894878706, Blast_Score=211, Evalue=7e-55,
Organism=Caenorhabditis elegans, GI71982178, Length=274, Percent_Identity=38.3211678832117, Blast_Score=207, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI32563615, Length=229, Percent_Identity=42.3580786026201, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI71985192, Length=300, Percent_Identity=37.3333333333333, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17551932, Length=357, Percent_Identity=30.5322128851541, Blast_Score=177, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI17505929, Length=373, Percent_Identity=29.4906166219839, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17531909, Length=237, Percent_Identity=34.5991561181435, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17562446, Length=287, Percent_Identity=30.3135888501742, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17531913, Length=176, Percent_Identity=31.8181818181818, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI86563383, Length=271, Percent_Identity=30.9963099630996, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI86563381, Length=271, Percent_Identity=30.9963099630996, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=47.8723404255319, Blast_Score=381, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24646207, Length=377, Percent_Identity=43.7665782493369, Blast_Score=337, Evalue=7e-93,
Organism=Drosophila melanogaster, GI24666513, Length=373, Percent_Identity=41.8230563002681, Blast_Score=306, Evalue=2e-83,
Organism=Drosophila melanogaster, GI24660351, Length=381, Percent_Identity=39.8950131233596, Blast_Score=291, Evalue=5e-79,
Organism=Drosophila melanogaster, GI21355753, Length=383, Percent_Identity=37.3368146214099, Blast_Score=259, Evalue=1e-69,
Organism=Drosophila melanogaster, GI281363737, Length=388, Percent_Identity=35.8247422680412, Blast_Score=225, Evalue=4e-59,
Organism=Drosophila melanogaster, GI19920834, Length=373, Percent_Identity=32.7077747989276, Blast_Score=188, Evalue=5e-48,
Organism=Drosophila melanogaster, GI281365206, Length=407, Percent_Identity=22.8501228501229, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24585193, Length=407, Percent_Identity=22.8501228501229, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24585195, Length=407, Percent_Identity=22.8501228501229, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24585191, Length=407, Percent_Identity=22.8501228501229, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 41416; Mature: 41416

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFALTREQEFVRQMVREFAETEVKPIAAEIDETERFPMENVEKMAKLGMMGIPIPKEYG
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCHHCCCCHHHHHHHHHCCCCCCCCCHHHC
GAGGDVLSYIIAVEELSKVCGTTGVIVSAHTSLCASLIYEHGTEEQKQKYLIPLAKGEKI
CCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCHHHHCEEEEECCCCEE
GAFGLTEPNAGTDAAGQQSVAIDMGDHYLLNGSKIFITNGGVADVAVVFAMTDRSKGTRG
CCCCCCCCCCCCCCCCCCEEEEECCCEEEECCCEEEEECCCHHHEEEEEEECCCCCCCCC
ISAFILEKGMPGFSVGKVEDKMGIRASSTTELIFEDVKVPKENLIGKEGRGFGIAMKTLD
HHHHHHHCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHCCCHHHCCCCCCCCCEEEEEECC
GGRIGIASQALGIAEGALEEAITYMKERKQFGRELYKFQGLSWMMADMKVAIESARLLVY
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
QAAWKKQNKLPYSEEAAMAKLHAANVAMDVTTKVVQLFGGYGYTKDYPVERMMRDAKITE
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
IYEGTSQVQQMVISGSLFR
HHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNFALTREQEFVRQMVREFAETEVKPIAAEIDETERFPMENVEKMAKLGMMGIPIPKEYG
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCHHCCCCHHHHHHHHHCCCCCCCCCHHHC
GAGGDVLSYIIAVEELSKVCGTTGVIVSAHTSLCASLIYEHGTEEQKQKYLIPLAKGEKI
CCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCHHHHCEEEEECCCCEE
GAFGLTEPNAGTDAAGQQSVAIDMGDHYLLNGSKIFITNGGVADVAVVFAMTDRSKGTRG
CCCCCCCCCCCCCCCCCCEEEEECCCEEEECCCEEEEECCCHHHEEEEEEECCCCCCCCC
ISAFILEKGMPGFSVGKVEDKMGIRASSTTELIFEDVKVPKENLIGKEGRGFGIAMKTLD
HHHHHHHCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHCCCHHHCCCCCCCCCEEEEEECC
GGRIGIASQALGIAEGALEEAITYMKERKQFGRELYKFQGLSWMMADMKVAIESARLLVY
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
QAAWKKQNKLPYSEEAAMAKLHAANVAMDVTTKVVQLFGGYGYTKDYPVERMMRDAKITE
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
IYEGTSQVQQMVISGSLFR
HHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]