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The map label for this gene is ribD [H]

Identifier: 28210395

GI number: 28210395

Start: 688536

End: 689678

Strand: Direct

Name: ribD [H]

Synonym: CTC00671

Alternate gene names: 28210395

Gene position: 688536-689678 (Clockwise)

Preceding gene: 28210391

Following gene: 28210396

Centisome position: 24.6

GC content: 29.83

Gene sequence:

>1143_bases
ATGAATTTTCACAATGTTTTCGTTATCTTTGAAGGATGGAACAAAAAGGAGATGATGAATTTGGATGAAATTTATATGAA
AAGAGCAATTGAATTAGCTCATTTGGGTGAGGGATATGTAAATCCTAATCCTTTAGTAGGAGCAGTTATAGTAAAGGATG
GAAGGATAATAGGAGAAGGATATCATAAAAAATTTGGAGAAGCTCATGCTGAAATAGAAGCCTTCAAAAGCTGTAAAGAG
GATCCAAAAGGTGGTACTTTATATGTTAATTTAGAACCTTGTTCCCACTATGGAAAGACTCCTCCTTGTGTAGATGTCAT
AATTAAAAAGGGTATAAAAAAAGTAATAATAGGTATGAAAGATCCTAATCCTTTAGTAGCAGGAAGAGGTTTAGAAATAT
TAAAAAAAGCTAACATAGAAGTAAGGGTTGGAACTTTAGAAGATGAATGTAGAAATTTAAATGAAATATTTATAAAATAT
ATAACTTATAAAAAACCATTTTGTATATTAAAATGGGCATCAACATTAGATGGAAAGATATGTTCGTCCATAGGAGATTC
TAGATGGATAACAGGAGAAGATTCAAGAGAATATGTGCATTTAATTAGAAATAAAGTAAGCTCTATAATGGTTGGAGTAA
ATACAATTCTAAGAGATAATCCTTCTTTAACCACAAGATTAAAAGATAGAAAAGGTGTAAATCCTACAAGAATTATTGTA
GATAGCAAAGGAAGAACACCCTTAGATGCAAGGATTTTTAAAGAAGAAGGGGACACTTTTATAGCAACTACTTCTCAAAT
TGAAGATAAGAAAATAAAAGAATTTGAAAAAGTAGGGGCTAAAATAATTATCATACCAGAAAAAGGTAGAAAAGTGGATT
TGCAATATCTTGTTAACTATTTAACAAAACTTAATATAGATAGCATACTTTTAGAAGGCGGTGGAACATTAAATTACTCA
GCCTTAAAAGAAGGCATTGTAGATAAAGTTCTCATGTTCCTAGCTCCTAAAATATTAGGTGGAGAAAATAGCAAAACACC
TATAGAAGGGGAGGGAATAAAGTATATTAAAGATTGCATAGAACTAAAGGATTTATCTATTAAAAATTTTAAAGAAGATA
TTTTGATAGAAGGCTTTATTTAG

Upstream 100 bases:

>100_bases
ACTTATGTAGCTAATTTAAGTTATATTATTTATTTTAGAATGTATTAGGTAAGAATACTTTACCCTGAAAGAATTAATTC
TTTCAGGGTTTTTTAGCGAC

Downstream 100 bases:

>100_bases
ATAATAACTAATAAAAGGTGGTGTTTTATTGTTTACGGGTATAGTAGAGGAATTAGGAAGTATAGAGAATATAGAAAAAA
AGGGAAACGCCTATAGCATA

Product: riboflavin biosynthesis protein

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MNFHNVFVIFEGWNKKEMMNLDEIYMKRAIELAHLGEGYVNPNPLVGAVIVKDGRIIGEGYHKKFGEAHAEIEAFKSCKE
DPKGGTLYVNLEPCSHYGKTPPCVDVIIKKGIKKVIIGMKDPNPLVAGRGLEILKKANIEVRVGTLEDECRNLNEIFIKY
ITYKKPFCILKWASTLDGKICSSIGDSRWITGEDSREYVHLIRNKVSSIMVGVNTILRDNPSLTTRLKDRKGVNPTRIIV
DSKGRTPLDARIFKEEGDTFIATTSQIEDKKIKEFEKVGAKIIIIPEKGRKVDLQYLVNYLTKLNIDSILLEGGGTLNYS
ALKEGIVDKVLMFLAPKILGGENSKTPIEGEGIKYIKDCIELKDLSIKNFKEDILIEGFI

Sequences:

>Translated_380_residues
MNFHNVFVIFEGWNKKEMMNLDEIYMKRAIELAHLGEGYVNPNPLVGAVIVKDGRIIGEGYHKKFGEAHAEIEAFKSCKE
DPKGGTLYVNLEPCSHYGKTPPCVDVIIKKGIKKVIIGMKDPNPLVAGRGLEILKKANIEVRVGTLEDECRNLNEIFIKY
ITYKKPFCILKWASTLDGKICSSIGDSRWITGEDSREYVHLIRNKVSSIMVGVNTILRDNPSLTTRLKDRKGVNPTRIIV
DSKGRTPLDARIFKEEGDTFIATTSQIEDKKIKEFEKVGAKIIIIPEKGRKVDLQYLVNYLTKLNIDSILLEGGGTLNYS
ALKEGIVDKVLMFLAPKILGGENSKTPIEGEGIKYIKDCIELKDLSIKNFKEDILIEGFI
>Mature_380_residues
MNFHNVFVIFEGWNKKEMMNLDEIYMKRAIELAHLGEGYVNPNPLVGAVIVKDGRIIGEGYHKKFGEAHAEIEAFKSCKE
DPKGGTLYVNLEPCSHYGKTPPCVDVIIKKGIKKVIIGMKDPNPLVAGRGLEILKKANIEVRVGTLEDECRNLNEIFIKY
ITYKKPFCILKWASTLDGKICSSIGDSRWITGEDSREYVHLIRNKVSSIMVGVNTILRDNPSLTTRLKDRKGVNPTRIIV
DSKGRTPLDARIFKEEGDTFIATTSQIEDKKIKEFEKVGAKIIIIPEKGRKVDLQYLVNYLTKLNIDSILLEGGGTLNYS
ALKEGIVDKVLMFLAPKILGGENSKTPIEGEGIKYIKDCIELKDLSIKNFKEDILIEGFI

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=367, Percent_Identity=38.4196185286104, Blast_Score=271, Evalue=6e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 42690; Mature: 42690

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFHNVFVIFEGWNKKEMMNLDEIYMKRAIELAHLGEGYVNPNPLVGAVIVKDGRIIGEG
CCCEEEEEEEECCCHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEECCH
YHKKFGEAHAEIEAFKSCKEDPKGGTLYVNLEPCSHYGKTPPCVDVIIKKGIKKVIIGMK
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHCCCCCCHHHHHHHHHCHHEEEEECC
DPNPLVAGRGLEILKKANIEVRVGTLEDECRNLNEIFIKYITYKKPFCILKWASTLDGKI
CCCCEEECCCHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHH
CSSIGDSRWITGEDSREYVHLIRNKVSSIMVGVNTILRDNPSLTTRLKDRKGVNPTRIIV
HHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHCCCCCCEEEEE
DSKGRTPLDARIFKEEGDTFIATTSQIEDKKIKEFEKVGAKIIIIPEKGRKVDLQYLVNY
ECCCCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCEEEEECCCCCEEEHHHHHHH
LTKLNIDSILLEGGGTLNYSALKEGIVDKVLMFLAPKILGGENSKTPIEGEGIKYIKDCI
HHHCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
ELKDLSIKNFKEDILIEGFI
HHHCCCHHCCCCCEEEECCC
>Mature Secondary Structure
MNFHNVFVIFEGWNKKEMMNLDEIYMKRAIELAHLGEGYVNPNPLVGAVIVKDGRIIGEG
CCCEEEEEEEECCCHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEECCH
YHKKFGEAHAEIEAFKSCKEDPKGGTLYVNLEPCSHYGKTPPCVDVIIKKGIKKVIIGMK
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHCCCCCCHHHHHHHHHCHHEEEEECC
DPNPLVAGRGLEILKKANIEVRVGTLEDECRNLNEIFIKYITYKKPFCILKWASTLDGKI
CCCCEEECCCHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHH
CSSIGDSRWITGEDSREYVHLIRNKVSSIMVGVNTILRDNPSLTTRLKDRKGVNPTRIIV
HHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHCCCCCCEEEEE
DSKGRTPLDARIFKEEGDTFIATTSQIEDKKIKEFEKVGAKIIIIPEKGRKVDLQYLVNY
ECCCCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCEEEEECCCCCEEEHHHHHHH
LTKLNIDSILLEGGGTLNYSALKEGIVDKVLMFLAPKILGGENSKTPIEGEGIKYIKDCI
HHHCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
ELKDLSIKNFKEDILIEGFI
HHHCCCHHCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]