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The map label for this gene is inlA [H]

Identifier: 28210241

GI number: 28210241

Start: 503151

End: 505238

Strand: Direct

Name: inlA [H]

Synonym: CTC00495

Alternate gene names: 28210241

Gene position: 503151-505238 (Clockwise)

Preceding gene: 28210240

Following gene: 28210245

Centisome position: 17.97

GC content: 27.78

Gene sequence:

>2088_bases
ATGAATAAGAAAAAAATTACTATAATAACTGCTGTAGCTTTAACTTGTGCTCTTAGTTTTTCTGTTTTAGCTTCTTATCC
TAATGAAGATAAGGCTTTAAGTAAAGGTGGAGTGGGAAAAGTTTTTGCTTTGGCAAGTTTAAATGAAAACAATATAAAAT
TCCCAGATAAAAATTTAGATATTGCTATAAGAGAGGCTACCAATAAAGAGCCTGATGCGACTCTTACTAAAAACGATTTT
AAAATGGTAACCAAGCTTAATTTAAAAAGTAAAAATATAAAAGATATTTCAGGATTAGAGTTTTTTGAAAATCTTCAAAG
TTTAGATTTAAGTAATAATGAGATAAAAGATTTAGGATCTTTAAGTGGTTTGAAGTATTTAAAAGAACTAACCCTATATA
AAAACAAAATAACAGATGTAAAAGCCTTAGACGGCCTAAAGAATTTAGAAAAGCTTAATCTAAGAGATAATAAGGTTAAG
AATATAGAAGGATTAAAAGGTTTAGAAAAATTAAGAGAATTAGATTTAGGTAAAAACTCTGTATTTCAACCAAAGCCTCT
TAAGGATTTGAAGAACTTGAGAATACTTAATTTAGAAAGTAATGGTATAGGCAATGCAGAGGATTTAGAAGAATTAAAGC
AAGTAGAACATTTAATTTTAAGTAATAATACTGTTGATGATGTGGAACCACTACTTACATTAACTAATGTAAATAAGCTT
TATTTAGATGATAATCCAGTTACACATATAGGAAAGCTTAAAGACATGACAAATCTAAAGAGACTTAATATAAACAACGA
TAGCATAGAGGATTTAGCAGAGCTTAAGAAGTTTAAAAATCTTCAGTGGTTAAAGTTTAAAAATCAGGAAATGGTATTGG
ATAATAAGAAATTAAATGATTTACTAGTAGATCCAAATAAAGAAGTTAAATTTGCAGATAAGAATTTAGAATTTGCTATA
AGAGATAAAATAGAGAAACCAAAAGGAGCAATAAAAAAGGCGGATTTGCAAAGGGTAACTCAACTAGATTTATGGGATAA
AAATGTTACGAATCTAGCAGGTATAGAAAACCTAATAGATTTAAGGGTTTTAAATGCTGGTAAAAATAATATAAGTAATT
TGGAACCATTGAAATCTATGGACAACTTAGAAAATTTATATTTAACTAAAACTAAAGTTGTAAGTCTTGAACCTTTAAGA
GGATTAACTAATTTAAAAGCATTAGTTATAAATGAAACAAATGTATCTGATTTAACTCCTATTAAGAATTTAATTAATTT
AGAAAGACTTACACTAGGAGATAATAAATTAGTATCCCTAGCGGGAATAGAGAATTTAGTTAACTTAGAATCTCTAGATA
TAAATAAAAATAATGTAAGTAATTTAGCTTCAATTAGAGATTTAACTAACTTAAAGTCATTAAATATTAATGAAAACAAT
GTAACAGATTTAAGTGTAGTTACAAACTTAAAGAATCTAGAGAGAATTTCTTTAAATAAAAATGGAGTGACTAGTCTAGG
AGCCTTAGCGGCATTACCAGAGCTTGAATGGGTTACAGCTAAGGAAAATGGATTAACAAGCACTGTAGGATTACAAAATG
CGTTAAAGCTTAAAGAACTATTTTTAGATAGTAACCAAATATCTGATTTATCATCTTTAGCTAATTTAACATCTTTAGAA
ACTTTAAGTCTAAGAACAAATAATATAAGTGATGTAAGTTCTCTAAGTGATTTAACAAGAATGAAGAATTTATATTTGCA
TAAAAACAATATAGGAAGTATTGCTCCACTTGCAAGTATGGAAAATTTAACAAGACTTTATGTTGGTAAGAATAATATTT
CAGATATAAGTGCAGTAGCAAACATGAAGAATTTAAAAACACTATCTATTGGAGAGAATATGGTATCCAATATAGGACCT
GTATCAGGATTACAAAGTTTAGAGACTCTTGATGTAGCAGATAACTTTATTACAGATGCTAGCCCAGCTATAGGATTACC
TAATCTTAAGGATATAATGCTTCTAAATACTAAAGTTCCAGAAGCTCAAATAAATGCGTTCCCAGATAGCGTAACAGTGA
CCAAATAG

Upstream 100 bases:

>100_bases
AATGCTCTTTCAAAAGACGTGAAGGTAGTTTATTAAGACTATCTGTGTAATTTAGTGTATTAACTAACGGAGGTGAAACT
GGTTAAATACCAGAAAGCAT

Downstream 100 bases:

>100_bases
GCGACAAATAGGGGACGGTTAATAAAAACTAAACCTCAAAAGCAGGAATTGCTTTTGGGGTTTAATTTTTTCGAACAAAG
AAGAGGGGGAAAGGTAAAGG

Product: internalin A-like protein/putative S-layer protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 695; Mature: 695

Protein sequence:

>695_residues
MNKKKITIITAVALTCALSFSVLASYPNEDKALSKGGVGKVFALASLNENNIKFPDKNLDIAIREATNKEPDATLTKNDF
KMVTKLNLKSKNIKDISGLEFFENLQSLDLSNNEIKDLGSLSGLKYLKELTLYKNKITDVKALDGLKNLEKLNLRDNKVK
NIEGLKGLEKLRELDLGKNSVFQPKPLKDLKNLRILNLESNGIGNAEDLEELKQVEHLILSNNTVDDVEPLLTLTNVNKL
YLDDNPVTHIGKLKDMTNLKRLNINNDSIEDLAELKKFKNLQWLKFKNQEMVLDNKKLNDLLVDPNKEVKFADKNLEFAI
RDKIEKPKGAIKKADLQRVTQLDLWDKNVTNLAGIENLIDLRVLNAGKNNISNLEPLKSMDNLENLYLTKTKVVSLEPLR
GLTNLKALVINETNVSDLTPIKNLINLERLTLGDNKLVSLAGIENLVNLESLDINKNNVSNLASIRDLTNLKSLNINENN
VTDLSVVTNLKNLERISLNKNGVTSLGALAALPELEWVTAKENGLTSTVGLQNALKLKELFLDSNQISDLSSLANLTSLE
TLSLRTNNISDVSSLSDLTRMKNLYLHKNNIGSIAPLASMENLTRLYVGKNNISDISAVANMKNLKTLSIGENMVSNIGP
VSGLQSLETLDVADNFITDASPAIGLPNLKDIMLLNTKVPEAQINAFPDSVTVTK

Sequences:

>Translated_695_residues
MNKKKITIITAVALTCALSFSVLASYPNEDKALSKGGVGKVFALASLNENNIKFPDKNLDIAIREATNKEPDATLTKNDF
KMVTKLNLKSKNIKDISGLEFFENLQSLDLSNNEIKDLGSLSGLKYLKELTLYKNKITDVKALDGLKNLEKLNLRDNKVK
NIEGLKGLEKLRELDLGKNSVFQPKPLKDLKNLRILNLESNGIGNAEDLEELKQVEHLILSNNTVDDVEPLLTLTNVNKL
YLDDNPVTHIGKLKDMTNLKRLNINNDSIEDLAELKKFKNLQWLKFKNQEMVLDNKKLNDLLVDPNKEVKFADKNLEFAI
RDKIEKPKGAIKKADLQRVTQLDLWDKNVTNLAGIENLIDLRVLNAGKNNISNLEPLKSMDNLENLYLTKTKVVSLEPLR
GLTNLKALVINETNVSDLTPIKNLINLERLTLGDNKLVSLAGIENLVNLESLDINKNNVSNLASIRDLTNLKSLNINENN
VTDLSVVTNLKNLERISLNKNGVTSLGALAALPELEWVTAKENGLTSTVGLQNALKLKELFLDSNQISDLSSLANLTSLE
TLSLRTNNISDVSSLSDLTRMKNLYLHKNNIGSIAPLASMENLTRLYVGKNNISDISAVANMKNLKTLSIGENMVSNIGP
VSGLQSLETLDVADNFITDASPAIGLPNLKDIMLLNTKVPEAQINAFPDSVTVTK
>Mature_695_residues
MNKKKITIITAVALTCALSFSVLASYPNEDKALSKGGVGKVFALASLNENNIKFPDKNLDIAIREATNKEPDATLTKNDF
KMVTKLNLKSKNIKDISGLEFFENLQSLDLSNNEIKDLGSLSGLKYLKELTLYKNKITDVKALDGLKNLEKLNLRDNKVK
NIEGLKGLEKLRELDLGKNSVFQPKPLKDLKNLRILNLESNGIGNAEDLEELKQVEHLILSNNTVDDVEPLLTLTNVNKL
YLDDNPVTHIGKLKDMTNLKRLNINNDSIEDLAELKKFKNLQWLKFKNQEMVLDNKKLNDLLVDPNKEVKFADKNLEFAI
RDKIEKPKGAIKKADLQRVTQLDLWDKNVTNLAGIENLIDLRVLNAGKNNISNLEPLKSMDNLENLYLTKTKVVSLEPLR
GLTNLKALVINETNVSDLTPIKNLINLERLTLGDNKLVSLAGIENLVNLESLDINKNNVSNLASIRDLTNLKSLNINENN
VTDLSVVTNLKNLERISLNKNGVTSLGALAALPELEWVTAKENGLTSTVGLQNALKLKELFLDSNQISDLSSLANLTSLE
TLSLRTNNISDVSSLSDLTRMKNLYLHKNNIGSIAPLASMENLTRLYVGKNNISDISAVANMKNLKTLSIGENMVSNIGP
VSGLQSLETLDVADNFITDASPAIGLPNLKDIMLLNTKVPEAQINAFPDSVTVTK

Specific function: Mediates the entry of Listeria monocytogenes into cells [H]

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 14 LRR (leucine-rich) repeats [H]

Homologues:

Organism=Homo sapiens, GI4506013, Length=185, Percent_Identity=33.5135135135135, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI206725447, Length=216, Percent_Identity=30.0925925925926, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI42542396, Length=216, Percent_Identity=30.0925925925926, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI55743114, Length=187, Percent_Identity=32.0855614973262, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI40255157, Length=353, Percent_Identity=28.6118980169972, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI209862903, Length=313, Percent_Identity=29.7124600638978, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI61966709, Length=209, Percent_Identity=36.3636363636364, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI120953243, Length=293, Percent_Identity=24.5733788395904, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI238908508, Length=592, Percent_Identity=25, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI120953300, Length=293, Percent_Identity=24.5733788395904, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI62912472, Length=350, Percent_Identity=28.8571428571429, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI194272224, Length=159, Percent_Identity=37.7358490566038, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI194272222, Length=159, Percent_Identity=37.7358490566038, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI62912470, Length=350, Percent_Identity=28.8571428571429, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI194272228, Length=159, Percent_Identity=37.7358490566038, Blast_Score=71, Evalue=4e-12,
Organism=Homo sapiens, GI194272226, Length=159, Percent_Identity=37.7358490566038, Blast_Score=71, Evalue=4e-12,
Organism=Homo sapiens, GI157694513, Length=405, Percent_Identity=25.679012345679, Blast_Score=70, Evalue=1e-11,
Organism=Homo sapiens, GI4758460, Length=304, Percent_Identity=28.6184210526316, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI21389483, Length=200, Percent_Identity=31.5, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI5901898, Length=182, Percent_Identity=29.1208791208791, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI55770895, Length=261, Percent_Identity=29.8850574712644, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI4504379, Length=316, Percent_Identity=27.2151898734177, Blast_Score=67, Evalue=8e-11,
Organism=Homo sapiens, GI8923909, Length=255, Percent_Identity=29.4117647058824, Blast_Score=67, Evalue=9e-11,
Organism=Homo sapiens, GI21361633, Length=280, Percent_Identity=27.1428571428571, Blast_Score=66, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI71984630, Length=661, Percent_Identity=25.1134644478064, Blast_Score=95, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17536161, Length=203, Percent_Identity=32.512315270936, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17554124, Length=196, Percent_Identity=33.6734693877551, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17531555, Length=245, Percent_Identity=27.3469387755102, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17554292, Length=217, Percent_Identity=33.6405529953917, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17554290, Length=217, Percent_Identity=33.6405529953917, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322655, Length=222, Percent_Identity=31.5315315315315, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21358617, Length=220, Percent_Identity=30.4545454545455, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21358607, Length=669, Percent_Identity=24.9626307922272, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI221330678, Length=188, Percent_Identity=30.3191489361702, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI85726404, Length=188, Percent_Identity=30.3191489361702, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221379725, Length=374, Percent_Identity=28.0748663101604, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221379722, Length=374, Percent_Identity=28.0748663101604, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI17136634, Length=563, Percent_Identity=25.7548845470693, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24658034, Length=231, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=6e-11,
Organism=Drosophila melanogaster, GI281363494, Length=144, Percent_Identity=36.8055555555556, Blast_Score=66, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR019948
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR013378
- InterPro:   IPR019931
- InterPro:   IPR012569
- InterPro:   IPR001899 [H]

Pfam domain/function: PF09479 Flg_new; PF00746 Gram_pos_anchor; PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 76934; Mature: 76934

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKKITIITAVALTCALSFSVLASYPNEDKALSKGGVGKVFALASLNENNIKFPDKNLD
CCCCEEEEHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCEEEEEEECCCCCCCCCCCCCC
IAIREATNKEPDATLTKNDFKMVTKLNLKSKNIKDISGLEFFENLQSLDLSNNEIKDLGS
EEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHH
LSGLKYLKELTLYKNKITDVKALDGLKNLEKLNLRDNKVKNIEGLKGLEKLRELDLGKNS
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
VFQPKPLKDLKNLRILNLESNGIGNAEDLEELKQVEHLILSNNTVDDVEPLLTLTNVNKL
CCCCCCHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEE
YLDDNPVTHIGKLKDMTNLKRLNINNDSIEDLAELKKFKNLQWLKFKNQEMVLDNKKLND
EECCCCCCHHHHHHHHCCCEEECCCCCCHHHHHHHHHHCCCEEEEECCCEEEECCCCCCC
LLVDPNKEVKFADKNLEFAIRDKIEKPKGAIKKADLQRVTQLDLWDKNVTNLAGIENLID
EEECCCCCEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LRVLNAGKNNISNLEPLKSMDNLENLYLTKTKVVSLEPLRGLTNLKALVINETNVSDLTP
EEEECCCCCCCCCCHHHHHHHHHHHEEEEEEEEEEECCCCCCCCCEEEEEECCCCCHHHH
IKNLINLERLTLGDNKLVSLAGIENLVNLESLDINKNNVSNLASIRDLTNLKSLNINENN
HHHHHHHHHEECCCCCEEEEHHHHHHHCCCEECCCCCCHHHHHHHHHHHCCCCCCCCCCC
VTDLSVVTNLKNLERISLNKNGVTSLGALAALPELEWVTAKENGLTSTVGLQNALKLKEL
CCHHHHHHHHHHHHEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHH
FLDSNQISDLSSLANLTSLETLSLRTNNISDVSSLSDLTRMKNLYLHKNNIGSIAPLASM
HHCCCHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHHHEEECCCCCCCCHHHHH
ENLTRLYVGKNNISDISAVANMKNLKTLSIGENMVSNIGPVSGLQSLETLDVADNFITDA
HHHHEEEECCCCCHHHHHHHHHHCCEEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
SPAIGLPNLKDIMLLNTKVPEAQINAFPDSVTVTK
CCCCCCCCCCCEEEEECCCCCHHHCCCCCCEEECC
>Mature Secondary Structure
MNKKKITIITAVALTCALSFSVLASYPNEDKALSKGGVGKVFALASLNENNIKFPDKNLD
CCCCEEEEHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCEEEEEEECCCCCCCCCCCCCC
IAIREATNKEPDATLTKNDFKMVTKLNLKSKNIKDISGLEFFENLQSLDLSNNEIKDLGS
EEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHH
LSGLKYLKELTLYKNKITDVKALDGLKNLEKLNLRDNKVKNIEGLKGLEKLRELDLGKNS
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
VFQPKPLKDLKNLRILNLESNGIGNAEDLEELKQVEHLILSNNTVDDVEPLLTLTNVNKL
CCCCCCHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEE
YLDDNPVTHIGKLKDMTNLKRLNINNDSIEDLAELKKFKNLQWLKFKNQEMVLDNKKLND
EECCCCCCHHHHHHHHCCCEEECCCCCCHHHHHHHHHHCCCEEEEECCCEEEECCCCCCC
LLVDPNKEVKFADKNLEFAIRDKIEKPKGAIKKADLQRVTQLDLWDKNVTNLAGIENLID
EEECCCCCEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LRVLNAGKNNISNLEPLKSMDNLENLYLTKTKVVSLEPLRGLTNLKALVINETNVSDLTP
EEEECCCCCCCCCCHHHHHHHHHHHEEEEEEEEEEECCCCCCCCCEEEEEECCCCCHHHH
IKNLINLERLTLGDNKLVSLAGIENLVNLESLDINKNNVSNLASIRDLTNLKSLNINENN
HHHHHHHHHEECCCCCEEEEHHHHHHHCCCEECCCCCCHHHHHHHHHHHCCCCCCCCCCC
VTDLSVVTNLKNLERISLNKNGVTSLGALAALPELEWVTAKENGLTSTVGLQNALKLKEL
CCHHHHHHHHHHHHEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHH
FLDSNQISDLSSLANLTSLETLSLRTNNISDVSSLSDLTRMKNLYLHKNNIGSIAPLASM
HHCCCHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHHHEEECCCCCCCCHHHHH
ENLTRLYVGKNNISDISAVANMKNLKTLSIGENMVSNIGPVSGLQSLETLDVADNFITDA
HHHHEEEECCCCCHHHHHHHHHHCCEEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
SPAIGLPNLKDIMLLNTKVPEAQINAFPDSVTVTK
CCCCCCCCCCCEEEEECCCCCHHHCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9541569 [H]