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The map label for this gene is inlA [H]

Identifier: 28210240

GI number: 28210240

Start: 500966

End: 503086

Strand: Direct

Name: inlA [H]

Synonym: CTC00494

Alternate gene names: 28210240

Gene position: 500966-503086 (Clockwise)

Preceding gene: 28210239

Following gene: 28210241

Centisome position: 17.9

GC content: 26.07

Gene sequence:

>2121_bases
TTGAATAAAATCGTACTTTATAAGAGAGGTGAAGGGCTAAAAGCCAATTTCATGAGAAAGAAAAAAATAACTATAATATT
ATTAACAGCTTTTTTGACAACTACAATAGTTCCAGCATTTGGAGTTACAATGCAGGGAAATAATTTCATAAATTCTAAAG
TACATGCTTATGATTTAGAAGAGGGAATAAAATTTCCAGATAAAGCACTAGAAAAGGTTATAAGAGAAAAAATCAATAAA
CCAGTGGGGCCTATAGAAAAAAGTGATTTATCTAATATATCAGAATTGGATATAAGAAATAAAGCGATAAAAAGTATAGA
AGGAATTCAATACCTTACAGGACTTCAAACTATTGATGCGGCAAATAACAAAATTCACGACCTGTCCCCTATAAGTGATT
GTACATCTCTTAGTAAAATAAACTTTTCTTATAATAAAATAGAGGATATATCAACACTTAAAAATTTAACTATTTTAGAG
AAGGTTTATTTAAAGGACAATGAAATTAAGAGAATAGATGCCCTAGAGGATTTAAAGGAGTTAAAGGAATTAGATTTAAG
TAGTAATGAAATAAAGAATTTAAAGTCACTAACTTATTTAAATAATCTTAAAACTTTGACTATGGCTGATAATGGATTAA
AGAATATAGATGATTTAGGATCTTTAGAAAAGCTTGAAAGTTTAACTCTTAGTAAAAATAATATTTCTGATATAAGTGCT
ATAAAGGTTATAAGAAATTTAACTAAGTTATATATAGATGATAATCAAGTAGAAGATGTGTATCCTCTTGTGGGAATGGA
TTATTTAGAGAGAATAAATTTAGATAAAAATAAGATAAAGAATATAGAAGAGTTAGAAGCAAATAAAGATAATTTGAAGT
GGGTTAAGTATAGAGGAAAAGAAATTACAGATATAGGTACTTTAAAATATATAGTTGAACAAGCAAATGTGGTAGTTAAT
TTTAAAGATAAAAATTTAGAAAGAGAAGTAAGAAAGAAAATAGAAAAGCCACTAGGAGAGTTAAGGCTCGCAGATGTTGA
GTATATAAAGGAGTTAAATTTATTTGCTAAGAATATAAAAGATATTTCTGGAATGGAATACCTAAGGGGACTAAGATGGG
TAAACCTGGGGAAAAATAATATAAGGGACATAAGCCCATTAAAGGATTTAGAAGATTTGGAAGGGCTATATCTTTATAAG
ACAAAGGTTTCAGATATAACTCCATTACAAGGACTAGAGAATCTTAAGAAACTACAAATTACAGCTACAAATTTATCAGA
ATTACATCCTCTTAAAAACTTAACTAATTTAGAAAGACTTGAGTTAGGAGAAAATAAAATATTTGAAGTAGAGGACTTAC
AAGGACTTATTAAATTAGAAGTGTTAGACTTAAGTGATAATTATATAAAAGATATATCTTCTCTTAAAAATCTAACAGAT
ATAAAGGAACTTAAACTTAATAAAAATAAAGTAAGTGATATAAGCATTGTAGCAAATATGAAAAATCTTCAAAGGTTATA
TATAAATGACAACAATATAACTACTCTAAAATATCTTAAAGATGCAAAAGATCTTGTATGGCTTACTGCAAACAATAATA
AAATAACTAGTTTTGAAGGATTAGAAAATCTTTTAGATATTAAAGAAATACATGTGGATAATAATAAAATATCTAAATTA
GATCCGCTTAAAAATCTAAAAGAACTAGAAACCCTAAGTGCTAGAACTAATGTAATATCTGATTTAAAGCCAATAGAAAA
CTTAGATTATATTAAGAATCTTTACTTATATGAAAATAAGATATCTGATATAAGTCCGTTAAAGAATATGACAGGAATGT
TAAGATTATATTTAGATAAAAATAATATTAAAGATATTTCTGTAGTAAGTAATATGAAAGATGTTACTACTTTAAGTCTA
GGAGATAATAATATAATTAATATAGCTCCAGTTGCTGGATTGGAGGATCTTGCTACTTTAGATATTGGAGATAATGATAT
AAAGGATATAACAGTTCTTTATAATCTACCATCTTTAGAGAAATTAGTTGTAACTAATAATGATAATTTACCAAAACATC
AAATAAATGCTCTTTCAAAAGACGTGAAGGTAGTTTATTAA

Upstream 100 bases:

>100_bases
TCACAAGAAAAAAATCAAATTATAGATGAAGGAAGTAGTATAAGTAATTAAAATTAATACCAGTTATAACATTCTTTATA
AGATTGCTTATAACTGGTAT

Downstream 100 bases:

>100_bases
GACTATCTGTGTAATTTAGTGTATTAACTAACGGAGGTGAAACTGGTTAAATACCAGAAAGCATATGAATAAGAAAAAAA
TTACTATAATAACTGCTGTA

Product: internalin A-like protein/putative S-layer protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 706; Mature: 706

Protein sequence:

>706_residues
MNKIVLYKRGEGLKANFMRKKKITIILLTAFLTTTIVPAFGVTMQGNNFINSKVHAYDLEEGIKFPDKALEKVIREKINK
PVGPIEKSDLSNISELDIRNKAIKSIEGIQYLTGLQTIDAANNKIHDLSPISDCTSLSKINFSYNKIEDISTLKNLTILE
KVYLKDNEIKRIDALEDLKELKELDLSSNEIKNLKSLTYLNNLKTLTMADNGLKNIDDLGSLEKLESLTLSKNNISDISA
IKVIRNLTKLYIDDNQVEDVYPLVGMDYLERINLDKNKIKNIEELEANKDNLKWVKYRGKEITDIGTLKYIVEQANVVVN
FKDKNLEREVRKKIEKPLGELRLADVEYIKELNLFAKNIKDISGMEYLRGLRWVNLGKNNIRDISPLKDLEDLEGLYLYK
TKVSDITPLQGLENLKKLQITATNLSELHPLKNLTNLERLELGENKIFEVEDLQGLIKLEVLDLSDNYIKDISSLKNLTD
IKELKLNKNKVSDISIVANMKNLQRLYINDNNITTLKYLKDAKDLVWLTANNNKITSFEGLENLLDIKEIHVDNNKISKL
DPLKNLKELETLSARTNVISDLKPIENLDYIKNLYLYENKISDISPLKNMTGMLRLYLDKNNIKDISVVSNMKDVTTLSL
GDNNIINIAPVAGLEDLATLDIGDNDIKDITVLYNLPSLEKLVVTNNDNLPKHQINALSKDVKVVY

Sequences:

>Translated_706_residues
MNKIVLYKRGEGLKANFMRKKKITIILLTAFLTTTIVPAFGVTMQGNNFINSKVHAYDLEEGIKFPDKALEKVIREKINK
PVGPIEKSDLSNISELDIRNKAIKSIEGIQYLTGLQTIDAANNKIHDLSPISDCTSLSKINFSYNKIEDISTLKNLTILE
KVYLKDNEIKRIDALEDLKELKELDLSSNEIKNLKSLTYLNNLKTLTMADNGLKNIDDLGSLEKLESLTLSKNNISDISA
IKVIRNLTKLYIDDNQVEDVYPLVGMDYLERINLDKNKIKNIEELEANKDNLKWVKYRGKEITDIGTLKYIVEQANVVVN
FKDKNLEREVRKKIEKPLGELRLADVEYIKELNLFAKNIKDISGMEYLRGLRWVNLGKNNIRDISPLKDLEDLEGLYLYK
TKVSDITPLQGLENLKKLQITATNLSELHPLKNLTNLERLELGENKIFEVEDLQGLIKLEVLDLSDNYIKDISSLKNLTD
IKELKLNKNKVSDISIVANMKNLQRLYINDNNITTLKYLKDAKDLVWLTANNNKITSFEGLENLLDIKEIHVDNNKISKL
DPLKNLKELETLSARTNVISDLKPIENLDYIKNLYLYENKISDISPLKNMTGMLRLYLDKNNIKDISVVSNMKDVTTLSL
GDNNIINIAPVAGLEDLATLDIGDNDIKDITVLYNLPSLEKLVVTNNDNLPKHQINALSKDVKVVY
>Mature_706_residues
MNKIVLYKRGEGLKANFMRKKKITIILLTAFLTTTIVPAFGVTMQGNNFINSKVHAYDLEEGIKFPDKALEKVIREKINK
PVGPIEKSDLSNISELDIRNKAIKSIEGIQYLTGLQTIDAANNKIHDLSPISDCTSLSKINFSYNKIEDISTLKNLTILE
KVYLKDNEIKRIDALEDLKELKELDLSSNEIKNLKSLTYLNNLKTLTMADNGLKNIDDLGSLEKLESLTLSKNNISDISA
IKVIRNLTKLYIDDNQVEDVYPLVGMDYLERINLDKNKIKNIEELEANKDNLKWVKYRGKEITDIGTLKYIVEQANVVVN
FKDKNLEREVRKKIEKPLGELRLADVEYIKELNLFAKNIKDISGMEYLRGLRWVNLGKNNIRDISPLKDLEDLEGLYLYK
TKVSDITPLQGLENLKKLQITATNLSELHPLKNLTNLERLELGENKIFEVEDLQGLIKLEVLDLSDNYIKDISSLKNLTD
IKELKLNKNKVSDISIVANMKNLQRLYINDNNITTLKYLKDAKDLVWLTANNNKITSFEGLENLLDIKEIHVDNNKISKL
DPLKNLKELETLSARTNVISDLKPIENLDYIKNLYLYENKISDISPLKNMTGMLRLYLDKNNIKDISVVSNMKDVTTLSL
GDNNIINIAPVAGLEDLATLDIGDNDIKDITVLYNLPSLEKLVVTNNDNLPKHQINALSKDVKVVY

Specific function: Mediates the entry of Listeria monocytogenes into cells [H]

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 14 LRR (leucine-rich) repeats [H]

Homologues:

Organism=Homo sapiens, GI4506013, Length=269, Percent_Identity=28.6245353159851, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI288541295, Length=294, Percent_Identity=27.5510204081633, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI288541297, Length=294, Percent_Identity=27.5510204081633, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI41281398, Length=455, Percent_Identity=25.9340659340659, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI21389483, Length=172, Percent_Identity=34.3023255813954, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI55743114, Length=188, Percent_Identity=28.1914893617021, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI157694513, Length=422, Percent_Identity=25.3554502369668, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI238908508, Length=611, Percent_Identity=24.5499181669394, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI40255157, Length=419, Percent_Identity=26.0143198090692, Blast_Score=70, Evalue=8e-12,
Organism=Homo sapiens, GI209862903, Length=412, Percent_Identity=26.4563106796117, Blast_Score=70, Evalue=8e-12,
Organism=Homo sapiens, GI7662320, Length=223, Percent_Identity=29.1479820627803, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17536161, Length=202, Percent_Identity=32.6732673267327, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71984630, Length=615, Percent_Identity=25.0406504065041, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17554124, Length=193, Percent_Identity=29.5336787564767, Blast_Score=89, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17531555, Length=281, Percent_Identity=26.3345195729537, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17508137, Length=451, Percent_Identity=25.4988913525499, Blast_Score=72, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6322455, Length=397, Percent_Identity=27.455919395466, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322655, Length=154, Percent_Identity=31.8181818181818, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21358617, Length=193, Percent_Identity=33.160621761658, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24664561, Length=577, Percent_Identity=23.5701906412478, Blast_Score=83, Evalue=8e-16,
Organism=Drosophila melanogaster, GI221500776, Length=650, Percent_Identity=24.3076923076923, Blast_Score=76, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24667524, Length=439, Percent_Identity=26.4236902050114, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17136634, Length=588, Percent_Identity=23.9795918367347, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17648023, Length=525, Percent_Identity=23.8095238095238, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI281362655, Length=220, Percent_Identity=28.6363636363636, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281362657, Length=220, Percent_Identity=28.6363636363636, Blast_Score=67, Evalue=5e-11,
Organism=Drosophila melanogaster, GI281362651, Length=220, Percent_Identity=28.6363636363636, Blast_Score=67, Evalue=5e-11,
Organism=Drosophila melanogaster, GI281362653, Length=218, Percent_Identity=28.4403669724771, Blast_Score=67, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17648021, Length=487, Percent_Identity=24.435318275154, Blast_Score=67, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR019948
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR013378
- InterPro:   IPR019931
- InterPro:   IPR012569
- InterPro:   IPR001899 [H]

Pfam domain/function: PF09479 Flg_new; PF00746 Gram_pos_anchor; PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 80457; Mature: 80457

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIVLYKRGEGLKANFMRKKKITIILLTAFLTTTIVPAFGVTMQGNNFINSKVHAYDLE
CCEEEEEECCCCCCHHHHHCCCEEEEHHHHHHHHHHHHHHCEEECCCCCCCCCEEEEEHH
EGIKFPDKALEKVIREKINKPVGPIEKSDLSNISELDIRNKAIKSIEGIQYLTGLQTIDA
HCCCCCHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ANNKIHDLSPISDCTSLSKINFSYNKIEDISTLKNLTILEKVYLKDNEIKRIDALEDLKE
CCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LKELDLSSNEIKNLKSLTYLNNLKTLTMADNGLKNIDDLGSLEKLESLTLSKNNISDISA
HHHCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHCHHHHHHHHHCCCCCCHHHHH
IKVIRNLTKLYIDDNQVEDVYPLVGMDYLERINLDKNKIKNIEELEANKDNLKWVKYRGK
HHHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCCCHHHHCCHHHHHCCCCCCEEEEECCC
EITDIGTLKYIVEQANVVVNFKDKNLEREVRKKIEKPLGELRLADVEYIKELNLFAKNIK
CCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCCHHHEEHHHHHHHHHHHHHHHHHH
DISGMEYLRGLRWVNLGKNNIRDISPLKDLEDLEGLYLYKTKVSDITPLQGLENLKKLQI
HCHHHHHHCCCEEEECCCCCCCCCCCHHHHHHCCCEEEEEECCCCCCCHHHHHHHHEEEE
TATNLSELHPLKNLTNLERLELGENKIFEVEDLQGLIKLEVLDLSDNYIKDISSLKNLTD
EECCHHHHHHHHHCCCCHHHHCCCCCEEEHHHHCCEEEEEEEECCCHHHHHHHHHHHHHH
IKELKLNKNKVSDISIVANMKNLQRLYINDNNITTLKYLKDAKDLVWLTANNNKITSFEG
HHHHHCCCCCCCHHHEEECHHHCEEEEECCCCEEEHHHHHCCCCEEEEEECCCEEEHHHH
LENLLDIKEIHVDNNKISKLDPLKNLKELETLSARTNVISDLKPIENLDYIKNLYLYENK
HHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
ISDISPLKNMTGMLRLYLDKNNIKDISVVSNMKDVTTLSLGDNNIINIAPVAGLEDLATL
CCCHHHHHHHHHEEEEEECCCCCCCHHHHCCCCCCEEEEECCCCEEEEECCCCCCHHEEE
DIGDNDIKDITVLYNLPSLEKLVVTNNDNLPKHQINALSKDVKVVY
ECCCCCCCEEEEEECCCCCEEEEEECCCCCCHHHHHHHCCCCEEEC
>Mature Secondary Structure
MNKIVLYKRGEGLKANFMRKKKITIILLTAFLTTTIVPAFGVTMQGNNFINSKVHAYDLE
CCEEEEEECCCCCCHHHHHCCCEEEEHHHHHHHHHHHHHHCEEECCCCCCCCCEEEEEHH
EGIKFPDKALEKVIREKINKPVGPIEKSDLSNISELDIRNKAIKSIEGIQYLTGLQTIDA
HCCCCCHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ANNKIHDLSPISDCTSLSKINFSYNKIEDISTLKNLTILEKVYLKDNEIKRIDALEDLKE
CCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LKELDLSSNEIKNLKSLTYLNNLKTLTMADNGLKNIDDLGSLEKLESLTLSKNNISDISA
HHHCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHCHHHHHHHHHCCCCCCHHHHH
IKVIRNLTKLYIDDNQVEDVYPLVGMDYLERINLDKNKIKNIEELEANKDNLKWVKYRGK
HHHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCCCHHHHCCHHHHHCCCCCCEEEEECCC
EITDIGTLKYIVEQANVVVNFKDKNLEREVRKKIEKPLGELRLADVEYIKELNLFAKNIK
CCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCCHHHEEHHHHHHHHHHHHHHHHHH
DISGMEYLRGLRWVNLGKNNIRDISPLKDLEDLEGLYLYKTKVSDITPLQGLENLKKLQI
HCHHHHHHCCCEEEECCCCCCCCCCCHHHHHHCCCEEEEEECCCCCCCHHHHHHHHEEEE
TATNLSELHPLKNLTNLERLELGENKIFEVEDLQGLIKLEVLDLSDNYIKDISSLKNLTD
EECCHHHHHHHHHCCCCHHHHCCCCCEEEHHHHCCEEEEEEEECCCHHHHHHHHHHHHHH
IKELKLNKNKVSDISIVANMKNLQRLYINDNNITTLKYLKDAKDLVWLTANNNKITSFEG
HHHHHCCCCCCCHHHEEECHHHCEEEEECCCCEEEHHHHHCCCCEEEEEECCCEEEHHHH
LENLLDIKEIHVDNNKISKLDPLKNLKELETLSARTNVISDLKPIENLDYIKNLYLYENK
HHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
ISDISPLKNMTGMLRLYLDKNNIKDISVVSNMKDVTTLSLGDNNIINIAPVAGLEDLATL
CCCHHHHHHHHHEEEEEECCCCCCCHHHHCCCCCCEEEEECCCCEEEEECCCCCCHHEEE
DIGDNDIKDITVLYNLPSLEKLVVTNNDNLPKHQINALSKDVKVVY
ECCCCCCCEEEEEECCCCCEEEEEECCCCCCHHHHHHHCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9541569 [H]