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The map label for this gene is 27366395

Identifier: 27366395

GI number: 27366395

Start: 3199772

End: 3200710

Strand: Reverse

Name: 27366395

Synonym: VV1_3129

Alternate gene names: NA

Gene position: 3200710-3199772 (Counterclockwise)

Preceding gene: 27366396

Following gene: 27366394

Centisome position: 97.53

GC content: 50.05

Gene sequence:

>939_bases
ATGATGAGCATTCCTCTGATCTATCACCCAATCTACTCTCAGTTGCCCCTGCCAGAGGGGCATCGTTACCCGATCATGAA
ATATCACCATCTTTATCAAGCGGTGTGTCGATATCAGCAACAGCATCTCGAGTGGCAGCAGGCATTTGCTTTTTATCAGC
CAGAAGCGTTATCGATTGAAGCCATTAAGCAAGTTCACCAACAAGAATATGTGGATCTGCTGACGACGGGCCTATTGCCT
GCGGCGAAAATGCGCAGAATTGGTTTTCCTTGGAGTGAAAAACTGATTGAACGCACGTTAACCTCAACCGCAGGCACTGT
GCTGACAGCGGAAAAAGCGTTGCAACATGGCGTTGCGATTCATCTCAGTGGCGGCTATCACCATGCCCATTTCGACTATG
GCAGCGGTTTTTGCTTGTTCAACGATCTCGTGATGGCTGCACATAAAGCGTTGGAACACGGCAGCGTCGACAAAGTGTTG
ATCATCGATAGCGATGTGCATCATGGCGATGGCACGGCCACTTTATGCCAACGGCGCGACGACATTGTGACGCTTTCTTT
CCATTGTGATAAGAATTTTCCTGCTCGTAAGCCGGACTCTGATCTCGATATTGGTTTGCCAAGAGAGTGCGGTGATGAGG
CGTTTCTTGCGGCGTTTAAAGAGGTGGTTCCGATGGCGATACGTCTCCATCAACCGGATCTCATTATCTACGATGCCGGT
GTCGACATTCATCATGAAGATGAGCTGGGATATCTCAACGTCTCCACCGACGCTTTGTATCAACGTGACGCTTTTCTCTT
TGGGCAGGCCAAAGCTAATGCGATCCCGGTTGCCGCGGTGGTAGGTGGTGGATATCGAACGGATCATGAAGCGCTGGTGC
CACTGCATTTGCAACTGCTCAACGCGGCGTTCGATGTGTATCGTTCTACACCAGATTGA

Upstream 100 bases:

>100_bases
TGGAGCGCCCAGAGTTTAAGCGCAAGAGACGCACCAGTAGCAGCAAGAAAACGGCGTCAACCGCGACCCAAAAAAGAACC
AACAAGTCGGCTTAAACCCC

Downstream 100 bases:

>100_bases
TGCATATTCGTGCCAAGATGTTTGCTCGAAAACGTTGTTTTGACAAAGTGTGCTATGCATCAACTTTCACTATAAATTTG
AATTAATTAAATAAGCGTAC

Product: Histone deacetylase/AcuC/AphA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MMSIPLIYHPIYSQLPLPEGHRYPIMKYHHLYQAVCRYQQQHLEWQQAFAFYQPEALSIEAIKQVHQQEYVDLLTTGLLP
AAKMRRIGFPWSEKLIERTLTSTAGTVLTAEKALQHGVAIHLSGGYHHAHFDYGSGFCLFNDLVMAAHKALEHGSVDKVL
IIDSDVHHGDGTATLCQRRDDIVTLSFHCDKNFPARKPDSDLDIGLPRECGDEAFLAAFKEVVPMAIRLHQPDLIIYDAG
VDIHHEDELGYLNVSTDALYQRDAFLFGQAKANAIPVAAVVGGGYRTDHEALVPLHLQLLNAAFDVYRSTPD

Sequences:

>Translated_312_residues
MMSIPLIYHPIYSQLPLPEGHRYPIMKYHHLYQAVCRYQQQHLEWQQAFAFYQPEALSIEAIKQVHQQEYVDLLTTGLLP
AAKMRRIGFPWSEKLIERTLTSTAGTVLTAEKALQHGVAIHLSGGYHHAHFDYGSGFCLFNDLVMAAHKALEHGSVDKVL
IIDSDVHHGDGTATLCQRRDDIVTLSFHCDKNFPARKPDSDLDIGLPRECGDEAFLAAFKEVVPMAIRLHQPDLIIYDAG
VDIHHEDELGYLNVSTDALYQRDAFLFGQAKANAIPVAAVVGGGYRTDHEALVPLHLQLLNAAFDVYRSTPD
>Mature_312_residues
MMSIPLIYHPIYSQLPLPEGHRYPIMKYHHLYQAVCRYQQQHLEWQQAFAFYQPEALSIEAIKQVHQQEYVDLLTTGLLP
AAKMRRIGFPWSEKLIERTLTSTAGTVLTAEKALQHGVAIHLSGGYHHAHFDYGSGFCLFNDLVMAAHKALEHGSVDKVL
IIDSDVHHGDGTATLCQRRDDIVTLSFHCDKNFPARKPDSDLDIGLPRECGDEAFLAAFKEVVPMAIRLHQPDLIIYDAG
VDIHHEDELGYLNVSTDALYQRDAFLFGQAKANAIPVAAVVGGGYRTDHEALVPLHLQLLNAAFDVYRSTPD

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI209862883, Length=248, Percent_Identity=26.2096774193548, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI217272877, Length=266, Percent_Identity=25.5639097744361, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI13128860, Length=262, Percent_Identity=28.6259541984733, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI293336691, Length=232, Percent_Identity=29.3103448275862, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI13128862, Length=259, Percent_Identity=27.027027027027, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI169234807, Length=189, Percent_Identity=30.6878306878307, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI148539870, Length=189, Percent_Identity=30.6878306878307, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI13128864, Length=179, Percent_Identity=31.2849162011173, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI8923769, Length=226, Percent_Identity=25.6637168141593, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI153085395, Length=169, Percent_Identity=34.3195266272189, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI20070354, Length=290, Percent_Identity=26.551724137931, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI193207430, Length=314, Percent_Identity=23.5668789808917, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17561978, Length=256, Percent_Identity=27.34375, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17534739, Length=276, Percent_Identity=27.536231884058, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17508561, Length=255, Percent_Identity=27.0588235294118, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17537347, Length=175, Percent_Identity=32, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI193206283, Length=181, Percent_Identity=30.939226519337, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17540332, Length=181, Percent_Identity=30.939226519337, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17540334, Length=181, Percent_Identity=30.939226519337, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321244, Length=259, Percent_Identity=28.1853281853282, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323999, Length=262, Percent_Identity=29.3893129770992, Blast_Score=92, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6324307, Length=271, Percent_Identity=25.830258302583, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6325325, Length=134, Percent_Identity=31.3432835820896, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24649807, Length=319, Percent_Identity=25.3918495297806, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24657891, Length=262, Percent_Identity=27.8625954198473, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24644244, Length=293, Percent_Identity=25.5972696245734, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281360899, Length=261, Percent_Identity=26.4367816091954, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24642144, Length=261, Percent_Identity=26.4367816091954, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24642146, Length=261, Percent_Identity=26.4367816091954, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24642142, Length=261, Percent_Identity=26.4367816091954, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641720, Length=199, Percent_Identity=32.1608040201005, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281360799, Length=199, Percent_Identity=32.1608040201005, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281360801, Length=199, Percent_Identity=32.1608040201005, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 35004; Mature: 35004

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSIPLIYHPIYSQLPLPEGHRYPIMKYHHLYQAVCRYQQQHLEWQQAFAFYQPEALSIE
CCCCCEEECCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
AIKQVHQQEYVDLLTTGLLPAAKMRRIGFPWSEKLIERTLTSTAGTVLTAEKALQHGVAI
HHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCEEEHHHHHHCCEEE
HLSGGYHHAHFDYGSGFCLFNDLVMAAHKALEHGSVDKVLIIDSDVHHGDGTATLCQRRD
EEECCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHCCCC
DIVTLSFHCDKNFPARKPDSDLDIGLPRECGDEAFLAAFKEVVPMAIRLHQPDLIIYDAG
CEEEEEEEECCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHEEECCCCEEEEECC
VDIHHEDELGYLNVSTDALYQRDAFLFGQAKANAIPVAAVVGGGYRTDHEALVPLHLQLL
CCEEECCCCCEEEECHHHHHHCCCEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHH
NAAFDVYRSTPD
HHHHHHHCCCCC
>Mature Secondary Structure
MMSIPLIYHPIYSQLPLPEGHRYPIMKYHHLYQAVCRYQQQHLEWQQAFAFYQPEALSIE
CCCCCEEECCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
AIKQVHQQEYVDLLTTGLLPAAKMRRIGFPWSEKLIERTLTSTAGTVLTAEKALQHGVAI
HHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCEEEHHHHHHCCEEE
HLSGGYHHAHFDYGSGFCLFNDLVMAAHKALEHGSVDKVLIIDSDVHHGDGTATLCQRRD
EEECCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHCCCC
DIVTLSFHCDKNFPARKPDSDLDIGLPRECGDEAFLAAFKEVVPMAIRLHQPDLIIYDAG
CEEEEEEEECCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHEEECCCCEEEEECC
VDIHHEDELGYLNVSTDALYQRDAFLFGQAKANAIPVAAVVGGGYRTDHEALVPLHLQLL
CCEEECCCCCEEEECHHHHHHCCCEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHH
NAAFDVYRSTPD
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]