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The map label for this gene is luxQ [H]

Identifier: 27366394

GI number: 27366394

Start: 3197370

End: 3199526

Strand: Reverse

Name: luxQ [H]

Synonym: VV1_3128

Alternate gene names: 27366394

Gene position: 3199526-3197370 (Counterclockwise)

Preceding gene: 27366395

Following gene: 27366393

Centisome position: 97.49

GC content: 46.31

Gene sequence:

>2157_bases
ATGGCAATGATAACGATTTGTCCCGAAACGCTTCCCATTGGTTGGCTTTCAATCACTCAAGAAGGATGGATTGAAGCGTA
TAACCAGCAAGCACAATCTTGTGAGCTTTGGCATCAACCCTTGATGGTAGGGGAAGCACTCACGTGCGTTCATCCCAGTC
GAATCTTTTATGAATGGGTAAAGCAGCTTTCCGCTCAATCCCCGCCACTCAGCATCATGTCTACCCGCGCGACGCATTGG
ACGCTTTCGGCAAGCCCAAGAACGCAAGGTGGTTTCGATTTATGGTTACAAGAAGCCGTTTGTGATGATGCGCTCAGGGA
CGAAAATACCCGCTTACGTCGTGACATTGAACGGCTTGACTTTGCTGCTCAAGGCGCGAATTTGGGCATTTGGGATTTCA
ATCCGTCAACGGGCTGTATCTTTGGCAATAAAACGTGGGCGACACAGAAAAAACTCGAACCTAATCATTTGTTTGCTGAT
GATGCTCTGTTTTCTGAGATCATCAATGGCATCGAAAAATGGTCTGAAATCGTTCACCCTGATGACGTGGCTGAAACCAC
AGATAAGATTCAAGCCCATTTAGACGGTGAGACGGAGCTCTACCATGCCGAGTTTCGCGTACGTTGCGGTGATGGTCAGT
GGAAATGGATTTTAGATCTTGGGCGAGTGTTCGAACGCGATCAAGATGGTGTCCCTGTGCGCATGAACGGCATCCATGTT
GATATCGATAAACTCAAGCGCCTGCAACAGAGTCTTTCTGAAACCAAAGACAAAGCGGAAGTGGCAAACCGTGCAAAATC
GATTTTTTTAGCCAACATGAGCCATGAGCTTCGCACACCGTTGAATGCCGTGTTGGGCTATACGCAGTTGATGAAGTGCG
ATCAACGCTTAACTGCAAAACACCACGAATATCTCGAAATCATTAACCGCTCTGGTGAGCACCTGTTATCGCTGATCAAC
GATGTGTTGGACATGTCAAAGATCGACGCTGGCCATAGTGTAGTAGAGCGCAAGTGGTTTAATTTCCGAGAAGTTTCTGA
AGAGATTAATGACCTCATGCAGATGAAGGCAATGCAAAAGCAACTGACATTGCACTGCCGCGTTGAAGATTCAGTACCGC
ATTTTGTATTAGGTGATGTCGTGAAAACGCGACAAGTGCTGATCAACTTGCTGGGAAATGCGATTAAATTTACATATCGA
GGCAATGTCCGTTTAAACATTGCCAGCGAGGCTTTGCAAAATGGCCAGCACAAAGTAACGTTTGAAGTGAGTGATTCGGG
CATTGGTATTAGTGAAGAAAACCAAGAACGCGTCTTCCAACCTTTTGAGCAACTGGATTCTGATATTACGCAAAATGGCA
CAGGGCTGGGATTGAGCATCAGTAAGCAGTTTGTCGAACTGATGGGAGGCCAATTGGTGCTCAAAAGTGAGCTTCATCGA
GGCTCTACTTTCTCATTCAGTCTTGTGATGGAAACCAGTGAGCATTTGGTTGAAAACAAGCCTGCGAATTTGCCCAGAGT
CTTAGGGTTAAAAAGTGGTTCATTCAGTCCTAAGATTTTGATCGCAGAAGACCAGCTAGACAACCAGACGTTGCTTGCCA
CGCTTTTGCAGGAAGCGGGCTTTACCGTCAAACTGGCCAGAGACGGCGAAGAAGCGGTTGCTCTGCATAAGAGTTGGGGC
CCTGATTTTATTTGGATGGATCGTCGTATGCCGAAAAAAGATGGCTTGCAAGCGACGAAAGAAATCCGTGCCGCCTCAGA
GAACAGCCAGGTAAAAATTGTTGCCTTGACCGCCAGTGTCTTTAATGACGAGATAGAAGAGATGTTAGCGTCAGGTATGG
ACGATTTTGCGCGTAAGCCGTTTATGCCGCAAGATTTGTTTTACATGATGAAGAAGCATCTCGATCTCGAGTATGACTAT
GAACAGAGGCAAGACGAGGCAGAGAACACATCCTTCGATGACTTGGATCTGAGCTTTTTGGATGATTTAACCCACGAGTC
GACTCAAGATATTGTTGAAGCGATAGAGCAAGGGCAGCAGCAGGAGCTCTATTACTTGTTCGAACAAACGATAGCGAACA
GTGAGGTTCGCACCCGTCTAAACAGCTTGGTAGAGAACTATCAATTTGATGAGCTTTACGAGTTATTTCAAGAATAA

Upstream 100 bases:

>100_bases
GATGGCCTTACTCTGAAGGTGGGCGTTAGGTCTTCGCACTCCTCGTTAACAAAAGCAAGCAATCAAAGGACAATGTCCTC
GAAGGGCATTGAGCAAGGGA

Downstream 100 bases:

>100_bases
AAAAGGGCATTGCGGGAAAAGCGTCGCAATGAAAGCAGATGAAAGTAGAACCATCGAATACGGAAATTTTGGTTGTTGAT
GATACCGTTGATAACGTCAA

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 718; Mature: 717

Protein sequence:

>718_residues
MAMITICPETLPIGWLSITQEGWIEAYNQQAQSCELWHQPLMVGEALTCVHPSRIFYEWVKQLSAQSPPLSIMSTRATHW
TLSASPRTQGGFDLWLQEAVCDDALRDENTRLRRDIERLDFAAQGANLGIWDFNPSTGCIFGNKTWATQKKLEPNHLFAD
DALFSEIINGIEKWSEIVHPDDVAETTDKIQAHLDGETELYHAEFRVRCGDGQWKWILDLGRVFERDQDGVPVRMNGIHV
DIDKLKRLQQSLSETKDKAEVANRAKSIFLANMSHELRTPLNAVLGYTQLMKCDQRLTAKHHEYLEIINRSGEHLLSLIN
DVLDMSKIDAGHSVVERKWFNFREVSEEINDLMQMKAMQKQLTLHCRVEDSVPHFVLGDVVKTRQVLINLLGNAIKFTYR
GNVRLNIASEALQNGQHKVTFEVSDSGIGISEENQERVFQPFEQLDSDITQNGTGLGLSISKQFVELMGGQLVLKSELHR
GSTFSFSLVMETSEHLVENKPANLPRVLGLKSGSFSPKILIAEDQLDNQTLLATLLQEAGFTVKLARDGEEAVALHKSWG
PDFIWMDRRMPKKDGLQATKEIRAASENSQVKIVALTASVFNDEIEEMLASGMDDFARKPFMPQDLFYMMKKHLDLEYDY
EQRQDEAENTSFDDLDLSFLDDLTHESTQDIVEAIEQGQQQELYYLFEQTIANSEVRTRLNSLVENYQFDELYELFQE

Sequences:

>Translated_718_residues
MAMITICPETLPIGWLSITQEGWIEAYNQQAQSCELWHQPLMVGEALTCVHPSRIFYEWVKQLSAQSPPLSIMSTRATHW
TLSASPRTQGGFDLWLQEAVCDDALRDENTRLRRDIERLDFAAQGANLGIWDFNPSTGCIFGNKTWATQKKLEPNHLFAD
DALFSEIINGIEKWSEIVHPDDVAETTDKIQAHLDGETELYHAEFRVRCGDGQWKWILDLGRVFERDQDGVPVRMNGIHV
DIDKLKRLQQSLSETKDKAEVANRAKSIFLANMSHELRTPLNAVLGYTQLMKCDQRLTAKHHEYLEIINRSGEHLLSLIN
DVLDMSKIDAGHSVVERKWFNFREVSEEINDLMQMKAMQKQLTLHCRVEDSVPHFVLGDVVKTRQVLINLLGNAIKFTYR
GNVRLNIASEALQNGQHKVTFEVSDSGIGISEENQERVFQPFEQLDSDITQNGTGLGLSISKQFVELMGGQLVLKSELHR
GSTFSFSLVMETSEHLVENKPANLPRVLGLKSGSFSPKILIAEDQLDNQTLLATLLQEAGFTVKLARDGEEAVALHKSWG
PDFIWMDRRMPKKDGLQATKEIRAASENSQVKIVALTASVFNDEIEEMLASGMDDFARKPFMPQDLFYMMKKHLDLEYDY
EQRQDEAENTSFDDLDLSFLDDLTHESTQDIVEAIEQGQQQELYYLFEQTIANSEVRTRLNSLVENYQFDELYELFQE
>Mature_717_residues
AMITICPETLPIGWLSITQEGWIEAYNQQAQSCELWHQPLMVGEALTCVHPSRIFYEWVKQLSAQSPPLSIMSTRATHWT
LSASPRTQGGFDLWLQEAVCDDALRDENTRLRRDIERLDFAAQGANLGIWDFNPSTGCIFGNKTWATQKKLEPNHLFADD
ALFSEIINGIEKWSEIVHPDDVAETTDKIQAHLDGETELYHAEFRVRCGDGQWKWILDLGRVFERDQDGVPVRMNGIHVD
IDKLKRLQQSLSETKDKAEVANRAKSIFLANMSHELRTPLNAVLGYTQLMKCDQRLTAKHHEYLEIINRSGEHLLSLIND
VLDMSKIDAGHSVVERKWFNFREVSEEINDLMQMKAMQKQLTLHCRVEDSVPHFVLGDVVKTRQVLINLLGNAIKFTYRG
NVRLNIASEALQNGQHKVTFEVSDSGIGISEENQERVFQPFEQLDSDITQNGTGLGLSISKQFVELMGGQLVLKSELHRG
STFSFSLVMETSEHLVENKPANLPRVLGLKSGSFSPKILIAEDQLDNQTLLATLLQEAGFTVKLARDGEEAVALHKSWGP
DFIWMDRRMPKKDGLQATKEIRAASENSQVKIVALTASVFNDEIEEMLASGMDDFARKPFMPQDLFYMMKKHLDLEYDYE
QRQDEAENTSFDDLDLSFLDDLTHESTQDIVEAIEQGQQQELYYLFEQTIANSEVRTRLNSLVENYQFDELYELFQE

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=253, Percent_Identity=41.1067193675889, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI48994928, Length=460, Percent_Identity=30, Blast_Score=190, Evalue=3e-49,
Organism=Escherichia coli, GI1788713, Length=477, Percent_Identity=29.979035639413, Blast_Score=185, Evalue=7e-48,
Organism=Escherichia coli, GI87081816, Length=395, Percent_Identity=29.873417721519, Blast_Score=163, Evalue=5e-41,
Organism=Escherichia coli, GI145693157, Length=260, Percent_Identity=34.2307692307692, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1786912, Length=264, Percent_Identity=26.1363636363636, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1788549, Length=240, Percent_Identity=26.25, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1786600, Length=234, Percent_Identity=26.9230769230769, Blast_Score=80, Evalue=7e-16,
Organism=Escherichia coli, GI1787894, Length=280, Percent_Identity=27.8571428571429, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790346, Length=201, Percent_Identity=29.3532338308458, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=219, Percent_Identity=26.027397260274, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788393, Length=253, Percent_Identity=24.1106719367589, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786783, Length=262, Percent_Identity=26.3358778625954, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI87082128, Length=232, Percent_Identity=29.3103448275862, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1790861, Length=294, Percent_Identity=25.1700680272109, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1788279, Length=202, Percent_Identity=24.7524752475248, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1788550, Length=120, Percent_Identity=31.6666666666667, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323034, Length=210, Percent_Identity=29.0476190476191, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=133, Percent_Identity=29.3233082706767, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=125, Percent_Identity=40, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 81971; Mature: 81839

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMITICPETLPIGWLSITQEGWIEAYNQQAQSCELWHQPLMVGEALTCVHPSRIFYEWV
CEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHH
KQLSAQSPPLSIMSTRATHWTLSASPRTQGGFDLWLQEAVCDDALRDENTRLRRDIERLD
HHHCCCCCCCHHEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FAAQGANLGIWDFNPSTGCIFGNKTWATQKKLEPNHLFADDALFSEIINGIEKWSEIVHP
HHHCCCCEEEEECCCCCCEEECCCCCCHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCC
DDVAETTDKIQAHLDGETELYHAEFRVRCGDGQWKWILDLGRVFERDQDGVPVRMNGIHV
CHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCEEHHHHHHHHHHCCCCCCCEEECCEEE
DIDKLKRLQQSLSETKDKAEVANRAKSIFLANMSHELRTPLNAVLGYTQLMKCDQRLTAK
CHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCHHHHHHHHHHHHHHHHHHHHH
HHEYLEIINRSGEHLLSLINDVLDMSKIDAGHSVVERKWFNFREVSEEINDLMQMKAMQK
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
QLTLHCRVEDSVPHFVLGDVVKTRQVLINLLGNAIKFTYRGNVRLNIASEALQNGQHKVT
HCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEHHHHHHCCCEEEE
FEVSDSGIGISEENQERVFQPFEQLDSDITQNGTGLGLSISKQFVELMGGQLVLKSELHR
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEHHHCC
GSTFSFSLVMETSEHLVENKPANLPRVLGLKSGSFSPKILIAEDQLDNQTLLATLLQEAG
CCCEEEEEEEHHHHHHHCCCCCCCCCEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHCC
FTVKLARDGEEAVALHKSWGPDFIWMDRRMPKKDGLQATKEIRAASENSQVKIVALTASV
CEEEEECCCCHHEEEECCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCEEEEEEEHHH
FNDEIEEMLASGMDDFARKPFMPQDLFYMMKKHLDLEYDYEQRQDEAENTSFDDLDLSFL
HHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHCHHCCCCCCCCCHHHH
DDLTHESTQDIVEAIEQGQQQELYYLFEQTIANSEVRTRLNSLVENYQFDELYELFQE
HHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHC
>Mature Secondary Structure 
AMITICPETLPIGWLSITQEGWIEAYNQQAQSCELWHQPLMVGEALTCVHPSRIFYEWV
EEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHH
KQLSAQSPPLSIMSTRATHWTLSASPRTQGGFDLWLQEAVCDDALRDENTRLRRDIERLD
HHHCCCCCCCHHEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FAAQGANLGIWDFNPSTGCIFGNKTWATQKKLEPNHLFADDALFSEIINGIEKWSEIVHP
HHHCCCCEEEEECCCCCCEEECCCCCCHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCC
DDVAETTDKIQAHLDGETELYHAEFRVRCGDGQWKWILDLGRVFERDQDGVPVRMNGIHV
CHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCEEHHHHHHHHHHCCCCCCCEEECCEEE
DIDKLKRLQQSLSETKDKAEVANRAKSIFLANMSHELRTPLNAVLGYTQLMKCDQRLTAK
CHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCHHHHHHHHHHHHHHHHHHHHH
HHEYLEIINRSGEHLLSLINDVLDMSKIDAGHSVVERKWFNFREVSEEINDLMQMKAMQK
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
QLTLHCRVEDSVPHFVLGDVVKTRQVLINLLGNAIKFTYRGNVRLNIASEALQNGQHKVT
HCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEHHHHHHCCCEEEE
FEVSDSGIGISEENQERVFQPFEQLDSDITQNGTGLGLSISKQFVELMGGQLVLKSELHR
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEHHHCC
GSTFSFSLVMETSEHLVENKPANLPRVLGLKSGSFSPKILIAEDQLDNQTLLATLLQEAG
CCCEEEEEEEHHHHHHHCCCCCCCCCEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHCC
FTVKLARDGEEAVALHKSWGPDFIWMDRRMPKKDGLQATKEIRAASENSQVKIVALTASV
CEEEEECCCCHHEEEECCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCEEEEEEEHHH
FNDEIEEMLASGMDDFARKPFMPQDLFYMMKKHLDLEYDYEQRQDEAENTSFDDLDLSFL
HHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHCHHCCCCCCCCCHHHH
DDLTHESTQDIVEAIEQGQQQELYYLFEQTIANSEVRTRLNSLVENYQFDELYELFQE
HHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA