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The map label for this gene is frdD

Identifier: 27364667

GI number: 27364667

Start: 1251560

End: 1251937

Strand: Reverse

Name: frdD

Synonym: VV1_1266

Alternate gene names: 27364667

Gene position: 1251937-1251560 (Counterclockwise)

Preceding gene: 27364668

Following gene: 27364664

Centisome position: 38.15

GC content: 49.74

Gene sequence:

>378_bases
ATGAAACCGAATTACAACGTAGATAGAGCGCCAAAACGTTCTGATGAGCCAGTTTGGTGGAGCTTGTTTGGTGCAGGTGG
TACTTGGTTTGCCATGATCACACCAGTTACTGTTTTGGTGCTGGGTATTCTCGTGCCAATGGGCGTGATCAATGCAGAAG
CACTGAGTTACGACCGAGTGGTGAGCTTTGCCACCAGCATCATCGGCGCATTGTTTATCATCGCGACACTGGCCTTACCA
ATGTGGCATGCGATGCACCGTGTTCACCACGGCATGCATGATCTCAAATTCCACACTGGCGTGGTCGGCAAAATTGCCTG
TTACGCGGTTGCTGGATTGATTTCAGCATTGGCGGTGGTGTTCATTTTCATGCTGTAA

Upstream 100 bases:

>100_bases
GGGCAAACCTGTTGATAAGAAAATCATCGTGCTCGCTCAGTGGGCGGCGGTGGCATTTATCTCACTGATCGTACTTATCG
TGGTGTAAGGAGCTTTAACG

Downstream 100 bases:

>100_bases
GCATGGCGCACTGAAAAAGAAAAAGCTGGCTTGTCGCCAGCTTTTTTATTGTCACTGCTTCAAGTGGTTTATTTATTGAC
CACTTTCTTGGTTTGGTCCA

Product: fumarate reductase subunit D

Products: fumarate; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MKPNYNVDRAPKRSDEPVWWSLFGAGGTWFAMITPVTVLVLGILVPMGVINAEALSYDRVVSFATSIIGALFIIATLALP
MWHAMHRVHHGMHDLKFHTGVVGKIACYAVAGLISALAVVFIFML

Sequences:

>Translated_125_residues
MKPNYNVDRAPKRSDEPVWWSLFGAGGTWFAMITPVTVLVLGILVPMGVINAEALSYDRVVSFATSIIGALFIIATLALP
MWHAMHRVHHGMHDLKFHTGVVGKIACYAVAGLISALAVVFIFML
>Mature_125_residues
MKPNYNVDRAPKRSDEPVWWSLFGAGGTWFAMITPVTVLVLGILVPMGVINAEALSYDRVVSFATSIIGALFIIATLALP
MWHAMHRVHHGMHDLKFHTGVVGKIACYAVAGLISALAVVFIFML

Specific function: Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane

COG id: COG3080

COG function: function code C; Fumarate reductase subunit D

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the frdD family

Homologues:

Organism=Escherichia coli, GI1790594, Length=114, Percent_Identity=48.2456140350877, Blast_Score=121, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FRDD_VIBVU (Q8DCX4)

Other databases:

- EMBL:   AE016795
- RefSeq:   NP_760195.1
- ProteinModelPortal:   Q8DCX4
- SMR:   Q8DCX4
- GeneID:   1178185
- GenomeReviews:   AE016795_GR
- KEGG:   vvu:VV1_1266
- HOGENOM:   HBG297136
- OMA:   HRIHHGM
- ProtClustDB:   PRK05470
- BioCyc:   VVUL216895:VV1_1266-MONOMER
- HAMAP:   MF_00709
- InterPro:   IPR003418
- ProDom:   PD015693

Pfam domain/function: PF02313 Fumarate_red_D

EC number: 1.3.99.1

Molecular weight: Translated: 13650; Mature: 13650

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xddb6828)-; HASH(0xe1a121c)-; HASH(0xdf317e8)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPNYNVDRAPKRSDEPVWWSLFGAGGTWFAMITPVTVLVLGILVPMGVINAEALSYDRV
CCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSFATSIIGALFIIATLALPMWHAMHRVHHGMHDLKFHTGVVGKIACYAVAGLISALAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
FIFML
HHHHH
>Mature Secondary Structure
MKPNYNVDRAPKRSDEPVWWSLFGAGGTWFAMITPVTVLVLGILVPMGVINAEALSYDRV
CCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSFATSIIGALFIIATLALPMWHAMHRVHHGMHDLKFHTGVVGKIACYAVAGLISALAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
FIFML
HHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; acceptor

Specific reaction: succinate + acceptor = fumarate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA