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The map label for this gene is yeeO [C]

Identifier: 27364659

GI number: 27364659

Start: 1243094

End: 1244440

Strand: Reverse

Name: yeeO [C]

Synonym: VV1_1258

Alternate gene names: 27364659

Gene position: 1244440-1243094 (Counterclockwise)

Preceding gene: 27364663

Following gene: 27364655

Centisome position: 37.92

GC content: 52.41

Gene sequence:

>1347_bases
ATGCTTGATAAACATGGCTTGCTGAGCGCGCCCATCGCGGAAACGCTACGAAAAATGACCGTCCCCATGATATTTGGCAT
GGTGGCGATCCTGATGTTTAACTTGGTCGACACCTTTTTCATCTCACTACTTGGCACCGAAGCACTGGCGGCGATCAGCT
ATACCTTCCCCGTCACCTTCGCCGTTAACTGCATTACGATGGGCATCGGGGTCGGACTATCGACCAGCATCGGTCGTCTA
TTAGGTCAAGGAGAAGCGCATCAAGCCGCACGTTTTACTACCCATGGCTTGCTATTGGCGGTTGTGCTGGTTGCGCTCGC
TTCCACACTCGGCTTCTTTACTGTCACCCCCTTATTTACCTTGCTTGGTGCGAAAGAGGAACTGATTCCCCTCATCGGCC
AATACATGCATGTCTGGTACCTCACCATCCCATTACTGGTGATTCCGATGGCAGGAAACAGTGCCATTCGTGCCACCGGA
GATACTAAGACCCCAGCCAAAATCATGATGCTCGCTGGGCTTATCAACGGCGTGCTCGACCCGCTGCTGATTTTTGGTAT
CGGCCCATTTCCTGAGCTCGGTATTCAAGGCGCAGCGATTGCGAGTGCGTTGAGTTGGCTCGGTGCGCTGATTGGCTCTT
TCTACGTTTTGATTCAGCGTGAGCGGCTGCTCGGCCTGCCACAATGGCAACGCTTAAAAGAGGATTGGCAGCAGATTCTC
AAGGTCGGCACTCCGGCTGCGCTTTCCAACGCAATGAACCCTCTCTCTGGCGCCATTTTAATGATGATGCTGTCCAGCCA
CGGCACCGCTGCTGTTGCCGCTTATGGGGCGGCACAACGCATTGAATCGATTTTGATTTTGGTCCTCATGGCACTCACCT
CTGCTCTGACGCCTTTTATGGCGCAAAACTTTGGCGCGAAAAACCCACAACGAGCGTTCCAAGGATTGTTCGTCAGCATG
CGCTTTTCGGTGCTGTTTCAAGGTTTGGTGTTTTTGATGATGGTGCCGCTCAGTATTCCGCTCGCCGCTCTATTCTCACA
AGAGCAAGCGGTAAGAGATTTGCTTTGGCATTACCTGCTGGTGGTACCGATCAGCTACGGTTTTTTAGGCATTGTGATGA
TGCTGGTCAGCGGTTTAAATGCCATGCACCAACCACTCAACGCCTTCCGCTGGAGCGTAATTCGGCTGTTTGTGTTTACC
CTGCCAGCGGCATACCTAGGCAGTTGGCTCTACGACATTGAAGGGCTGTTTATTGGCATTGCGGTGGGCAACATTTTGGT
CGGGTTGTGCAGCTATCTTTACGCCCTTAAGCAACGCAAACAGCAATTGGCCACATTAGTGCCTTAG

Upstream 100 bases:

>100_bases
TGGCAAAGGATTGCTTAAAAACAGCTCGCTCGCCCCTCGCACACATTTCTTGTATCCTAGCGCTTTTGCACCTTCTGGTG
ATGCCTTCTGGTGATGATTG

Downstream 100 bases:

>100_bases
ATTTGACGTCTGGTAGAAGCCACCGATATGAAAAAGGCTGCGATAACGCAGCCTTTGCTCAGATAATCAGTTTATTCTGC
TTAGAATAGCTCTTCTGCTA

Product: Na+-driven multidrug efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MLDKHGLLSAPIAETLRKMTVPMIFGMVAILMFNLVDTFFISLLGTEALAAISYTFPVTFAVNCITMGIGVGLSTSIGRL
LGQGEAHQAARFTTHGLLLAVVLVALASTLGFFTVTPLFTLLGAKEELIPLIGQYMHVWYLTIPLLVIPMAGNSAIRATG
DTKTPAKIMMLAGLINGVLDPLLIFGIGPFPELGIQGAAIASALSWLGALIGSFYVLIQRERLLGLPQWQRLKEDWQQIL
KVGTPAALSNAMNPLSGAILMMMLSSHGTAAVAAYGAAQRIESILILVLMALTSALTPFMAQNFGAKNPQRAFQGLFVSM
RFSVLFQGLVFLMMVPLSIPLAALFSQEQAVRDLLWHYLLVVPISYGFLGIVMMLVSGLNAMHQPLNAFRWSVIRLFVFT
LPAAYLGSWLYDIEGLFIGIAVGNILVGLCSYLYALKQRKQQLATLVP

Sequences:

>Translated_448_residues
MLDKHGLLSAPIAETLRKMTVPMIFGMVAILMFNLVDTFFISLLGTEALAAISYTFPVTFAVNCITMGIGVGLSTSIGRL
LGQGEAHQAARFTTHGLLLAVVLVALASTLGFFTVTPLFTLLGAKEELIPLIGQYMHVWYLTIPLLVIPMAGNSAIRATG
DTKTPAKIMMLAGLINGVLDPLLIFGIGPFPELGIQGAAIASALSWLGALIGSFYVLIQRERLLGLPQWQRLKEDWQQIL
KVGTPAALSNAMNPLSGAILMMMLSSHGTAAVAAYGAAQRIESILILVLMALTSALTPFMAQNFGAKNPQRAFQGLFVSM
RFSVLFQGLVFLMMVPLSIPLAALFSQEQAVRDLLWHYLLVVPISYGFLGIVMMLVSGLNAMHQPLNAFRWSVIRLFVFT
LPAAYLGSWLYDIEGLFIGIAVGNILVGLCSYLYALKQRKQQLATLVP
>Mature_448_residues
MLDKHGLLSAPIAETLRKMTVPMIFGMVAILMFNLVDTFFISLLGTEALAAISYTFPVTFAVNCITMGIGVGLSTSIGRL
LGQGEAHQAARFTTHGLLLAVVLVALASTLGFFTVTPLFTLLGAKEELIPLIGQYMHVWYLTIPLLVIPMAGNSAIRATG
DTKTPAKIMMLAGLINGVLDPLLIFGIGPFPELGIQGAAIASALSWLGALIGSFYVLIQRERLLGLPQWQRLKEDWQQIL
KVGTPAALSNAMNPLSGAILMMMLSSHGTAAVAAYGAAQRIESILILVLMALTSALTPFMAQNFGAKNPQRAFQGLFVSM
RFSVLFQGLVFLMMVPLSIPLAALFSQEQAVRDLLWHYLLVVPISYGFLGIVMMLVSGLNAMHQPLNAFRWSVIRLFVFT
LPAAYLGSWLYDIEGLFIGIAVGNILVGLCSYLYALKQRKQQLATLVP

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=358, Percent_Identity=22.9050279329609, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48477; Mature: 48477

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDKHGLLSAPIAETLRKMTVPMIFGMVAILMFNLVDTFFISLLGTEALAAISYTFPVTF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVNCITMGIGVGLSTSIGRLLGQGEAHQAARFTTHGLLLAVVLVALASTLGFFTVTPLFT
HHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGAKEELIPLIGQYMHVWYLTIPLLVIPMAGNSAIRATGDTKTPAKIMMLAGLINGVLD
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHH
PLLIFGIGPFPELGIQGAAIASALSWLGALIGSFYVLIQRERLLGLPQWQRLKEDWQQIL
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KVGTPAALSNAMNPLSGAILMMMLSSHGTAAVAAYGAAQRIESILILVLMALTSALTPFM
HCCCCHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQNFGAKNPQRAFQGLFVSMRFSVLFQGLVFLMMVPLSIPLAALFSQEQAVRDLLWHYLL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVPISYGFLGIVMMLVSGLNAMHQPLNAFRWSVIRLFVFTLPAAYLGSWLYDIEGLFIGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGNILVGLCSYLYALKQRKQQLATLVP
HHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLDKHGLLSAPIAETLRKMTVPMIFGMVAILMFNLVDTFFISLLGTEALAAISYTFPVTF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVNCITMGIGVGLSTSIGRLLGQGEAHQAARFTTHGLLLAVVLVALASTLGFFTVTPLFT
HHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGAKEELIPLIGQYMHVWYLTIPLLVIPMAGNSAIRATGDTKTPAKIMMLAGLINGVLD
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHH
PLLIFGIGPFPELGIQGAAIASALSWLGALIGSFYVLIQRERLLGLPQWQRLKEDWQQIL
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KVGTPAALSNAMNPLSGAILMMMLSSHGTAAVAAYGAAQRIESILILVLMALTSALTPFM
HCCCCHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQNFGAKNPQRAFQGLFVSMRFSVLFQGLVFLMMVPLSIPLAALFSQEQAVRDLLWHYLL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVPISYGFLGIVMMLVSGLNAMHQPLNAFRWSVIRLFVFTLPAAYLGSWLYDIEGLFIGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGNILVGLCSYLYALKQRKQQLATLVP
HHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]