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The map label for this gene is hemX [H]

Identifier: 27364541

GI number: 27364541

Start: 1120040

End: 1121251

Strand: Reverse

Name: hemX [H]

Synonym: VV1_1120

Alternate gene names: 27364541

Gene position: 1121251-1120040 (Counterclockwise)

Preceding gene: 27364542

Following gene: 27364540

Centisome position: 34.17

GC content: 49.83

Gene sequence:

>1212_bases
ATGACAAGTAAAAAAAATAACGAGCCAAATAAGCCTGAAGAAACAACTTCTCAACCAATAACCTCTGACGCCTCCACGCC
AGAAACATCGAACACCGAATCGACTGCGTCCGTTTCAGCCGATGAACCAACGGTGACACCAACAACACCGCCACCAGCAG
CCGCTGCAAAGAAAGAAGATAAAAAACCGAGCCAAAAACTCAGTATCCTTGCCATCATCATTGCGTTGTTGGGCACTGGC
GGCGTGGCGTTCCAGCTTCAACAGCAAAACAGCCAATATCAGGCACAAATCGCTGCGCTGCAAAATCAGTTGCAACAAAC
GCAAAGCGCGATGAGCACTGAGCTTAACCAAGTGAAGCAAGAGACCGTCGCCAAAGCGACCGAAGTCACTCACAAAGCAG
AAGTGGTGCTGGCTCAGCAGCAGAAAAGCATCGAAAGCTTGCAACTTGCAATGGCGGACGTAAAAGGCCGTCGCCCGAAC
GATTGGTTATTGGCGGAAGCCGACTACCTCGTCAAACTGGCGGGCCGAAAACTGTTCCTTGAGCATGACGTCGTGAGTGC
CACCAGCTTGATGGAAAGTGCCGACCAACGCATCGCGGCACTCAACGATCCAAGCCTCGTGCCTCTGCGCAAAGCGATGG
CCAAAGACATTACCGATCTGAAAACCATTCCACTGATTGACCGCGATGGTTTAGTACTGCGTTTGACCGCACTGCAACAA
CAAGTCGACCAATTGCCATTGGCAAATGCCATTCTGCCAGAAGCGAAGACCGTCGAGAAACAACAAGTCTCTGACGACAT
CAACAACTGGCAAAACAACTTAATGGCGTCGCTCAAAGCCTTCTCAGAGAACTTTATTACCTTCCGTACTCGCGATGGCA
ACGTCATTCCACTGTTGTCGCCAGAGCAGCACTTCTATCTGAAAGAGAACATCAAAGCGAAGATCGAAACCGCCATCAAA
GCGGTCTATCAAGAACAAGGTGAGGTTTACACCACCTCACTCACCACCGCAGAAGCGTGGTCGCAAGCGTTCTTTAACCA
AGATAACAACACGGTGAAAGAGTTTACTCAGTCGTTGAAACAGCTCAGCGAGCAAAAAATTCAGGTGCAATACCCTGTAA
AACTGCAAACGCAAAATCAATTGGCGGATGTAATTCGTGAACGTCTACGCCGTGAAGTCACTAGCATGACCAGCACGGAG
GCGCAGCAATGA

Upstream 100 bases:

>100_bases
TTGCGACCCAACTTGGCTTTACTCAGGTTTGCAATGTAGGAAGTGCCTCGAACAAAGATTTACTGGCTGCTCTCCAGCCT
AAGTAACACAGGACAAACTC

Downstream 100 bases:

>100_bases
TTCGTTTGATCTTCCTCTTTGTCGTGCTTGGTGCCGGGCTGTTTGTCGGTACCCAGTTTTCTGGCCAGCAGGGTTATGTG
CTGATCTCGATCGCCAACAC

Product: HemX-like protein

Products: NA

Alternate protein names: Urogen-III methylase; ORF X [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MTSKKNNEPNKPEETTSQPITSDASTPETSNTESTASVSADEPTVTPTTPPPAAAAKKEDKKPSQKLSILAIIIALLGTG
GVAFQLQQQNSQYQAQIAALQNQLQQTQSAMSTELNQVKQETVAKATEVTHKAEVVLAQQQKSIESLQLAMADVKGRRPN
DWLLAEADYLVKLAGRKLFLEHDVVSATSLMESADQRIAALNDPSLVPLRKAMAKDITDLKTIPLIDRDGLVLRLTALQQ
QVDQLPLANAILPEAKTVEKQQVSDDINNWQNNLMASLKAFSENFITFRTRDGNVIPLLSPEQHFYLKENIKAKIETAIK
AVYQEQGEVYTTSLTTAEAWSQAFFNQDNNTVKEFTQSLKQLSEQKIQVQYPVKLQTQNQLADVIRERLRREVTSMTSTE
AQQ

Sequences:

>Translated_403_residues
MTSKKNNEPNKPEETTSQPITSDASTPETSNTESTASVSADEPTVTPTTPPPAAAAKKEDKKPSQKLSILAIIIALLGTG
GVAFQLQQQNSQYQAQIAALQNQLQQTQSAMSTELNQVKQETVAKATEVTHKAEVVLAQQQKSIESLQLAMADVKGRRPN
DWLLAEADYLVKLAGRKLFLEHDVVSATSLMESADQRIAALNDPSLVPLRKAMAKDITDLKTIPLIDRDGLVLRLTALQQ
QVDQLPLANAILPEAKTVEKQQVSDDINNWQNNLMASLKAFSENFITFRTRDGNVIPLLSPEQHFYLKENIKAKIETAIK
AVYQEQGEVYTTSLTTAEAWSQAFFNQDNNTVKEFTQSLKQLSEQKIQVQYPVKLQTQNQLADVIRERLRREVTSMTSTE
AQQ
>Mature_402_residues
TSKKNNEPNKPEETTSQPITSDASTPETSNTESTASVSADEPTVTPTTPPPAAAAKKEDKKPSQKLSILAIIIALLGTGG
VAFQLQQQNSQYQAQIAALQNQLQQTQSAMSTELNQVKQETVAKATEVTHKAEVVLAQQQKSIESLQLAMADVKGRRPND
WLLAEADYLVKLAGRKLFLEHDVVSATSLMESADQRIAALNDPSLVPLRKAMAKDITDLKTIPLIDRDGLVLRLTALQQQ
VDQLPLANAILPEAKTVEKQQVSDDINNWQNNLMASLKAFSENFITFRTRDGNVIPLLSPEQHFYLKENIKAKIETAIKA
VYQEQGEVYTTSLTTAEAWSQAFFNQDNNTVKEFTQSLKQLSEQKIQVQYPVKLQTQNQLADVIRERLRREVTSMTSTEA
QQ

Specific function: Siroheme and cobalamin biosynthesis. [C]

COG id: COG2959

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790235, Length=362, Percent_Identity=35.9116022099448, Blast_Score=201, Evalue=5e-53,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007470 [H]

Pfam domain/function: PF04375 HemX [H]

EC number: =2.1.1.107 [H]

Molecular weight: Translated: 44699; Mature: 44568

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSKKNNEPNKPEETTSQPITSDASTPETSNTESTASVSADEPTVTPTTPPPAAAAKKED
CCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCC
KKPSQKLSILAIIIALLGTGGVAFQLQQQNSQYQAQIAALQNQLQQTQSAMSTELNQVKQ
CCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETVAKATEVTHKAEVVLAQQQKSIESLQLAMADVKGRRPNDWLLAEADYLVKLAGRKLFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHCCEEEE
EHDVVSATSLMESADQRIAALNDPSLVPLRKAMAKDITDLKTIPLIDRDGLVLRLTALQQ
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCEECCCCCEEEHHHHHH
QVDQLPLANAILPEAKTVEKQQVSDDINNWQNNLMASLKAFSENFITFRTRDGNVIPLLS
HHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEC
PEQHFYLKENIKAKIETAIKAVYQEQGEVYTTSLTTAEAWSQAFFNQDNNTVKEFTQSLK
CCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHCCCCCHHHHHHHHHH
QLSEQKIQVQYPVKLQTQNQLADVIRERLRREVTSMTSTEAQQ
HHHHCCEEEEECEEECCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TSKKNNEPNKPEETTSQPITSDASTPETSNTESTASVSADEPTVTPTTPPPAAAAKKED
CCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCC
KKPSQKLSILAIIIALLGTGGVAFQLQQQNSQYQAQIAALQNQLQQTQSAMSTELNQVKQ
CCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETVAKATEVTHKAEVVLAQQQKSIESLQLAMADVKGRRPNDWLLAEADYLVKLAGRKLFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHCCEEEE
EHDVVSATSLMESADQRIAALNDPSLVPLRKAMAKDITDLKTIPLIDRDGLVLRLTALQQ
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCEECCCCCEEEHHHHHH
QVDQLPLANAILPEAKTVEKQQVSDDINNWQNNLMASLKAFSENFITFRTRDGNVIPLLS
HHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEC
PEQHFYLKENIKAKIETAIKAVYQEQGEVYTTSLTTAEAWSQAFFNQDNNTVKEFTQSLK
CCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHCCCCCHHHHHHHHHH
QLSEQKIQVQYPVKLQTQNQLADVIRERLRREVTSMTSTEAQQ
HHHHCCEEEEECEEECCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3062586; 3054815; 1379743; 9278503; 9298646 [H]