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The map label for this gene is purE [H]

Identifier: 27364486

GI number: 27364486

Start: 1056330

End: 1056815

Strand: Reverse

Name: purE [H]

Synonym: VV1_1054

Alternate gene names: 27364486

Gene position: 1056815-1056330 (Counterclockwise)

Preceding gene: 27364491

Following gene: 27364485

Centisome position: 32.2

GC content: 51.85

Gene sequence:

>486_bases
ATGAAAGTCGGTATCATCATGGGTTCTAAATCAGATTGGCCAACCATGAAACTGGCAGCAGAAATGCTGGACAGATTTGG
CGTGGAATACGAAACCAAAGTGGTTTCAGCACATCGAACTCCTCATCTCCTCGCTGAATATGCCTCAACCGCCAAAGAGC
GTGGGTTGAAAGTGATTATTGCCGGTGCAGGTGGCGCGGCGCATTTGCCGGGCATGGCAGCGGCATTTACCAGCTTGCCC
GTTTTGGGCGTACCCGTGCAATCACGTGCTTTATCAGGGCTCGACTCTCTCTACTCTATTGTGCAAATGCCAAAAGGCAT
CGCAGTAGGTACATTGGCCATTGGTGAAGCCGGTGCCGCGAACGCGGGTCTTCTCGCTGCGCAAATCCTTGGAACTCACG
ACGAAAATATCATGGCCAAAGTTGAAGCCTTCCGCAGTGAGCAAACTGAAAGCGTCCTCGCTAACCCAAATCCTGCAGAG
GACTAA

Upstream 100 bases:

>100_bases
TTTCCACTCAAAAGCAAACGTTTGCTTGAGGTAAAAAACCTCGTATAATGCGCACAAAATTGATCAGCTCACCCAATTAT
GCAGCTTGAAGGAGTTTGAG

Downstream 100 bases:

>100_bases
ATCATGCACGTATTGGTTCTAGGCGCAGGGCAATTGGCACGTATGATGTCGTTAGCCGGTGCGCCTTTGAATATTCAGAT
TTCTGCCTACGATGTGACAA

Product: phosphoribosylaminoimidazole carboxylase catalytic subunit

Products: NA

Alternate protein names: N5-CAIR mutase; 5-(carboxyamino)imidazole ribonucleotide mutase [H]

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MKVGIIMGSKSDWPTMKLAAEMLDRFGVEYETKVVSAHRTPHLLAEYASTAKERGLKVIIAGAGGAAHLPGMAAAFTSLP
VLGVPVQSRALSGLDSLYSIVQMPKGIAVGTLAIGEAGAANAGLLAAQILGTHDENIMAKVEAFRSEQTESVLANPNPAE
D

Sequences:

>Translated_161_residues
MKVGIIMGSKSDWPTMKLAAEMLDRFGVEYETKVVSAHRTPHLLAEYASTAKERGLKVIIAGAGGAAHLPGMAAAFTSLP
VLGVPVQSRALSGLDSLYSIVQMPKGIAVGTLAIGEAGAANAGLLAAQILGTHDENIMAKVEAFRSEQTESVLANPNPAE
D
>Mature_161_residues
MKVGIIMGSKSDWPTMKLAAEMLDRFGVEYETKVVSAHRTPHLLAEYASTAKERGLKVIIAGAGGAAHLPGMAAAFTSLP
VLGVPVQSRALSGLDSLYSIVQMPKGIAVGTLAIGEAGAANAGLLAAQILGTHDENIMAKVEAFRSEQTESVLANPNPAE
D

Specific function: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) [H]

COG id: COG0041

COG function: function code F; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR carboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786734, Length=157, Percent_Identity=64.968152866242, Blast_Score=172, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6324702, Length=151, Percent_Identity=56.953642384106, Blast_Score=172, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: =5.4.99.18 [H]

Molecular weight: Translated: 16696; Mature: 16696

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVGIIMGSKSDWPTMKLAAEMLDRFGVEYETKVVSAHRTPHLLAEYASTAKERGLKVII
CEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHEECCCCCHHHHHHHHHHHHHCCCEEEE
AGAGGAAHLPGMAAAFTSLPVLGVPVQSRALSGLDSLYSIVQMPKGIAVGTLAIGEAGAA
ECCCCCCCCCHHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
NAGLLAAQILGTHDENIMAKVEAFRSEQTESVLANPNPAED
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKVGIIMGSKSDWPTMKLAAEMLDRFGVEYETKVVSAHRTPHLLAEYASTAKERGLKVII
CEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHEECCCCCHHHHHHHHHHHHHCCCEEEE
AGAGGAAHLPGMAAAFTSLPVLGVPVQSRALSGLDSLYSIVQMPKGIAVGTLAIGEAGAA
ECCCCCCCCCHHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
NAGLLAAQILGTHDENIMAKVEAFRSEQTESVLANPNPAED
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]