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The map label for this gene is rlmM [H]

Identifier: 255961266

GI number: 255961266

Start: 4398281

End: 4399381

Strand: Reverse

Name: rlmM [H]

Synonym: Pfl01_3889

Alternate gene names: 255961266

Gene position: 4399381-4398281 (Counterclockwise)

Preceding gene: 77460112

Following gene: 255961267

Centisome position: 68.33

GC content: 62.49

Gene sequence:

>1101_bases
ATGATCGCCCTCTGCCCAGGAGTAAGAATGAACACCCTATTCATGCATTGCCGGCCAGGCTTCGAAGGCGAAGTCTGCTC
GGAGATTTCCGACCTCGCCGCCCGACTGAATGTGGCCGGCTACGCCAAGGCCAAACCGGCCACCGCTTGCGCCGAGTTCG
TCTGCACCGAAGAAGACGGTGCCGAGCGCCTGATGCGCGGTCAGCGTTTCGCCGAGCTGATCTTCCCGCGCCAATGGGCG
CGCGGGTTTTTCATCGATCTGCCGGAAAACGACCGTATCAGCGTGATCCTCGCTCACATGAGTGAATTCCCGGTGTGCGG
CAGCCTGTGGCTGGAAGTCGTCGACACCAACGACGGCAAGGAGCTGTCGAACTTCTGCAAGAAATTCGAAGGCCCGCTGC
GCAAGGCCCTGACCGGTGCCGGCAAACTGGTGGAGGACACCAGCAAGCCGCGTCTGCTGCTGACCTTCAAGAGCGGCCGT
GAGGTGTTTCTCGGTCTGGCCGACGCCGGTAACTCGGCGATGTGGCCGATGGGCATTCCGCGCCTGAAGTTCCCGCGTGA
GGCGCCGAGCCGTTCGACCCTGAAACTGGAAGAAGCCTGGCACCACTTCATCCCCCGCGACCAGTGGGAAGATCGCCTGC
ACAGCGACATGACCGGCGTGGATCTCGGCGCGGCGCCGGGCGGCTGGACCTGGCAGCTGGTCAATCGCGGCATGCTGGTG
ACTGCTATCGACAACGGCCCGATGGCCGAAAGCCTGATGGACACCGGTCTGGTGCAGCACCTGATGGCTGACGGCTTCAC
CTTCAAGCCCAAGCAGCCGGTGGACTGGATGGTTTGCGACATCGTCGAGAAACCGGCGCGCAATGCCGCGATGCTCGAAG
AGTGGATCGGCGAGGGGCATTGCCGGGAAGCGGTGGTCAACCTCAAGTTGCCGATGAAGCAGCGTTACGCCGAAGTGAAG
CGCCTGCTCGAACGCATCGCCGATGGTTTCAAGGCCCGTGGGATCAAGGTCGACATCGGCTGCAAGCAGCTTTACCACGA
CCGCGAGGAAGTGACCTGCCATTTGCGCCGCCTTGACGTGAAGAAAGCCAAAGCCCGCTGA

Upstream 100 bases:

>100_bases
ACTCTATGGGCAAGTCCAAGGTTCCGACATGGGCTATCATGCGCCGGTTTTCGTGACAGGCTTTGCTTCAATGCAGGTCT
GGGCATCGCGCAGGGGATGA

Downstream 100 bases:

>100_bases
GCGCACGACAGGTGACCGAAGACCCAGCATTGGGCGACAATGCCGGCCAGTTTCAGGAGTGAATCATGAGTGAAATGATC
AATACGCCGGTCGACGGCAC

Product: putative RNA 2'-O-ribose methyltransferase

Products: NA

Alternate protein names: 23S rRNA 2'-O-ribose methyltransferase rlmM [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MIALCPGVRMNTLFMHCRPGFEGEVCSEISDLAARLNVAGYAKAKPATACAEFVCTEEDGAERLMRGQRFAELIFPRQWA
RGFFIDLPENDRISVILAHMSEFPVCGSLWLEVVDTNDGKELSNFCKKFEGPLRKALTGAGKLVEDTSKPRLLLTFKSGR
EVFLGLADAGNSAMWPMGIPRLKFPREAPSRSTLKLEEAWHHFIPRDQWEDRLHSDMTGVDLGAAPGGWTWQLVNRGMLV
TAIDNGPMAESLMDTGLVQHLMADGFTFKPKQPVDWMVCDIVEKPARNAAMLEEWIGEGHCREAVVNLKLPMKQRYAEVK
RLLERIADGFKARGIKVDIGCKQLYHDREEVTCHLRRLDVKKAKAR

Sequences:

>Translated_366_residues
MIALCPGVRMNTLFMHCRPGFEGEVCSEISDLAARLNVAGYAKAKPATACAEFVCTEEDGAERLMRGQRFAELIFPRQWA
RGFFIDLPENDRISVILAHMSEFPVCGSLWLEVVDTNDGKELSNFCKKFEGPLRKALTGAGKLVEDTSKPRLLLTFKSGR
EVFLGLADAGNSAMWPMGIPRLKFPREAPSRSTLKLEEAWHHFIPRDQWEDRLHSDMTGVDLGAAPGGWTWQLVNRGMLV
TAIDNGPMAESLMDTGLVQHLMADGFTFKPKQPVDWMVCDIVEKPARNAAMLEEWIGEGHCREAVVNLKLPMKQRYAEVK
RLLERIADGFKARGIKVDIGCKQLYHDREEVTCHLRRLDVKKAKAR
>Mature_366_residues
MIALCPGVRMNTLFMHCRPGFEGEVCSEISDLAARLNVAGYAKAKPATACAEFVCTEEDGAERLMRGQRFAELIFPRQWA
RGFFIDLPENDRISVILAHMSEFPVCGSLWLEVVDTNDGKELSNFCKKFEGPLRKALTGAGKLVEDTSKPRLLLTFKSGR
EVFLGLADAGNSAMWPMGIPRLKFPREAPSRSTLKLEEAWHHFIPRDQWEDRLHSDMTGVDLGAAPGGWTWQLVNRGMLV
TAIDNGPMAESLMDTGLVQHLMADGFTFKPKQPVDWMVCDIVEKPARNAAMLEEWIGEGHCREAVVNLKLPMKQRYAEVK
RLLERIADGFKARGIKVDIGCKQLYHDREEVTCHLRRLDVKKAKAR

Specific function: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA [H]

COG id: COG2933

COG function: function code R; Predicted SAM-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmE family. RlmM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789171, Length=355, Percent_Identity=48.169014084507, Blast_Score=326, Evalue=1e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011224
- InterPro:   IPR002877 [H]

Pfam domain/function: PF01728 FtsJ [H]

EC number: NA

Molecular weight: Translated: 41186; Mature: 41186

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALCPGVRMNTLFMHCRPGFEGEVCSEISDLAARLNVAGYAKAKPATACAEFVCTEEDG
CEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCH
AERLMRGQRFAELIFPRQWARGFFIDLPENDRISVILAHMSEFPVCGSLWLEVVDTNDGK
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEHHHCCCCHHHHHEEEEECCCCH
ELSNFCKKFEGPLRKALTGAGKLVEDTSKPRLLLTFKSGREVFLGLADAGNSAMWPMGIP
HHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCC
RLKFPREAPSRSTLKLEEAWHHFIPRDQWEDRLHSDMTGVDLGAAPGGWTWQLVNRGMLV
CCCCCCCCCCCCCEEHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEECCCEEE
TAIDNGPMAESLMDTGLVQHLMADGFTFKPKQPVDWMVCDIVEKPARNAAMLEEWIGEGH
EEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCH
CREAVVNLKLPMKQRYAEVKRLLERIADGFKARGIKVDIGCKQLYHDREEVTCHLRRLDV
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHCCHHHHHHHHHHHHH
KKAKAR
HHHCCC
>Mature Secondary Structure
MIALCPGVRMNTLFMHCRPGFEGEVCSEISDLAARLNVAGYAKAKPATACAEFVCTEEDG
CEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCH
AERLMRGQRFAELIFPRQWARGFFIDLPENDRISVILAHMSEFPVCGSLWLEVVDTNDGK
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEHHHCCCCHHHHHEEEEECCCCH
ELSNFCKKFEGPLRKALTGAGKLVEDTSKPRLLLTFKSGREVFLGLADAGNSAMWPMGIP
HHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCC
RLKFPREAPSRSTLKLEEAWHHFIPRDQWEDRLHSDMTGVDLGAAPGGWTWQLVNRGMLV
CCCCCCCCCCCCCEEHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEECCCEEE
TAIDNGPMAESLMDTGLVQHLMADGFTFKPKQPVDWMVCDIVEKPARNAAMLEEWIGEGH
EEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCH
CREAVVNLKLPMKQRYAEVKRLLERIADGFKARGIKVDIGCKQLYHDREEVTCHLRRLDV
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHCCHHHHHHHHHHHHH
KKAKAR
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA