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The map label for this gene is str [H]

Identifier: 77460112

GI number: 77460112

Start: 4402607

End: 4403422

Strand: Reverse

Name: str [H]

Synonym: Pfl01_3891

Alternate gene names: 77460112

Gene position: 4403422-4402607 (Counterclockwise)

Preceding gene: 77460113

Following gene: 255961266

Centisome position: 68.39

GC content: 64.95

Gene sequence:

>816_bases
GTGGCTGATCTCGACCTGTTCGCGCCGTGGCTGGGACGCTGGGCGCTGGCGCCGGACGGCGAGCCGATCATCACCCCGGG
CAGCCGCCTGTTGCCGGTGCGTCAGGACGATACTCCGGCGATGCTGAAAGTCGCGGTGGACGACGAAGAAAAGTACGGCA
ACCTGCTGATGACCTGGTGGGACGGCGACGGCGCCGCCCGGGTGCTTGCCCATCACGACGAAGGCCTGTTGCTGGAGCGG
GCGATGGGCCAGCGTTCGTTGATGCACATGGCGCTCAACGGCGAGGACGACGAGGCCTCGCGGATCATGTGCCGATCCTT
GGCCCGGCTGCACGCACCGCGTCTGACGCCGCCACCGCCGTTGGTGGAACTCGCGCCGTGGTTCGCATCATTACGAGTGG
CGGCGACCCGATACGGCGGCCAATACGCCGAATGCCTGCAAACCGCCCAGACCTTGCTTGCCGAGCCGCATGACGTAGTG
GTGCTGCACGGCGACATGCACCACGACAACGTCCTCGATTTCGGCCCACGGGGCTGGCTGGCCATCGACCCCAAGCGGGT
GCAGGGCGAGCGCGGTTATGACTACGCCAACCTGATCTGCAACCCGGAATTGCAGACGGCCACCGATCCGGAGCGCTTTC
GGCACCAAGTCAATGTGATCTGCGAAGCAGCGGCAATTGAACGCAAGCGCCTGCTGCAATGGGTACTGGCCTTCGCCGGA
CTGTCTGCCGCGTGGTTCATGGAAGATGACGAGCGAAAAGCCGCCAACGGACAGCTGAAAGTCGCGCAACTGGCGGCTTC
TGCACTTGATGCCTGA

Upstream 100 bases:

>100_bases
CAGAAAGAGGCCTACTACATGGACAGTCGGGGCTGGGAGGAACAGTTGAGTCGACTTGAGCACTTCCTCACGGAGAGCGA
CCGGGCCCGTGAGCGTGAAG

Downstream 100 bases:

>100_bases
CACGCCTAAGGGTTTTCGGAAGGCCTGCTATGGCGAATGTCTTACACGCGCTGGTAGCTTTTTCGACTATTGCCGATTGG
ATCCAGAGCGTAATCTAGCC

Product: aminoglycoside/hydroxyurea antibiotic resistance kinase

Products: NA

Alternate protein names: Streptomycin 3''-phosphotransferase; SPH [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MADLDLFAPWLGRWALAPDGEPIITPGSRLLPVRQDDTPAMLKVAVDDEEKYGNLLMTWWDGDGAARVLAHHDEGLLLER
AMGQRSLMHMALNGEDDEASRIMCRSLARLHAPRLTPPPPLVELAPWFASLRVAATRYGGQYAECLQTAQTLLAEPHDVV
VLHGDMHHDNVLDFGPRGWLAIDPKRVQGERGYDYANLICNPELQTATDPERFRHQVNVICEAAAIERKRLLQWVLAFAG
LSAAWFMEDDERKAANGQLKVAQLAASALDA

Sequences:

>Translated_271_residues
MADLDLFAPWLGRWALAPDGEPIITPGSRLLPVRQDDTPAMLKVAVDDEEKYGNLLMTWWDGDGAARVLAHHDEGLLLER
AMGQRSLMHMALNGEDDEASRIMCRSLARLHAPRLTPPPPLVELAPWFASLRVAATRYGGQYAECLQTAQTLLAEPHDVV
VLHGDMHHDNVLDFGPRGWLAIDPKRVQGERGYDYANLICNPELQTATDPERFRHQVNVICEAAAIERKRLLQWVLAFAG
LSAAWFMEDDERKAANGQLKVAQLAASALDA
>Mature_270_residues
ADLDLFAPWLGRWALAPDGEPIITPGSRLLPVRQDDTPAMLKVAVDDEEKYGNLLMTWWDGDGAARVLAHHDEGLLLERA
MGQRSLMHMALNGEDDEASRIMCRSLARLHAPRLTPPPPLVELAPWFASLRVAATRYGGQYAECLQTAQTLLAEPHDVVV
LHGDMHHDNVLDFGPRGWLAIDPKRVQGERGYDYANLICNPELQTATDPERFRHQVNVICEAAAIERKRLLQWVLAFAGL
SAAWFMEDDERKAANGQLKVAQLAASALDA

Specific function: The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation [H]

COG id: COG3570

COG function: function code V; Streptomycin 6-kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aminoglycoside phosphotransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006748 [H]

Pfam domain/function: PF04655 APH_6_hur [H]

EC number: =2.7.1.87 [H]

Molecular weight: Translated: 30114; Mature: 29982

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLDLFAPWLGRWALAPDGEPIITPGSRLLPVRQDDTPAMLKVAVDDEEKYGNLLMTWW
CCCHHHHHHHHCCEEECCCCCEEECCCCCEEEECCCCCCEEEEEEECCCCCCCCEEEEEE
DGDGAARVLAHHDEGLLLERAMGQRSLMHMALNGEDDEASRIMCRSLARLHAPRLTPPPP
CCCCEEEEEEECCCCHHHHHHHCHHHHEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCC
LVELAPWFASLRVAATRYGGQYAECLQTAQTLLAEPHDVVVLHGDMHHDNVLDFGPRGWL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCE
AIDPKRVQGERGYDYANLICNPELQTATDPERFRHQVNVICEAAAIERKRLLQWVLAFAG
EECHHHHCCCCCCCHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LSAAWFMEDDERKAANGQLKVAQLAASALDA
CCEEEEECCCCHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
ADLDLFAPWLGRWALAPDGEPIITPGSRLLPVRQDDTPAMLKVAVDDEEKYGNLLMTWW
CCHHHHHHHHCCEEECCCCCEEECCCCCEEEECCCCCCEEEEEEECCCCCCCCEEEEEE
DGDGAARVLAHHDEGLLLERAMGQRSLMHMALNGEDDEASRIMCRSLARLHAPRLTPPPP
CCCCEEEEEEECCCCHHHHHHHCHHHHEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCC
LVELAPWFASLRVAATRYGGQYAECLQTAQTLLAEPHDVVVLHGDMHHDNVLDFGPRGWL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCE
AIDPKRVQGERGYDYANLICNPELQTATDPERFRHQVNVICEAAAIERKRLLQWVLAFAG
EECHHHHCCCCCCCHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LSAAWFMEDDERKAANGQLKVAQLAASALDA
CCEEEEECCCCHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3889831 [H]