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The map label for this gene is yvrH

Identifier: 255767758

GI number: 255767758

Start: 3408353

End: 3409066

Strand: Reverse

Name: yvrH

Synonym: BSU33221

Alternate gene names: 255767758

Gene position: 3409066-3408353 (Counterclockwise)

Preceding gene: 255767759

Following gene: 255767757

Centisome position: 80.87

GC content: 45.8

Gene sequence:

>714_bases
GTGGAAAATGCGTCAATTTTAATCGTAGACGATGAGAAAGCGATTGTGGACATGATCAAACGCGTTCTCGAAAAAGAAGG
TTATCGAAATATACTGGATGCGGCAAGCGCAGAAGAAGCGATTCCCGTTGTGAAGGCCAATAAGGTTGACTTGATTGTGC
TGGATGTCATGATGGGCGGAATGTCCGGTTTTGAAGCCTGCACATTGATCAGAGAGTATTCAGACGCTCCGATTTTTTTC
CTGACGGCAAGATCATCCGACGCGGACAAATTATCGGGCTTTGCGGTTGGAGCTGATGACTATATCACAAAACCATTTAA
TCCGCTGGAATTAGCGGCGCGGATCAGAGCGCATCTCAAGCGTACATATCAATCGAAAGAAACGAGTTCAAATCAAACCT
ACACATATGATTACTTTACTTTTTCTCCGCAAAATGCCGAGTTGATCGTAGGCGGGGAAGCCGTTGCCTGTTCAGCCCAG
CTTCTGCAGCTTTTGCAGTATTTTTGTGAACACCCTAACGTGGTGCTTTCCAAAGATCAAATATATGAAAAAGTATGGGG
CTATCCTTCCTACGGTGACAACAACACCGTCATGGTTCATATTCGCAAGCTTAGGGAGAAGATTGAGCGCGATCCGAGCA
ATCCGGAGTATATTGTAACCGTTCGAGGTCTCGGCTATCGTTTTATCCCAAATCCTGAAGGCAAGCGGTCATGA

Upstream 100 bases:

>100_bases
CTGTTTTGATTTGCCAAGGCTCCAATGTATTCAAAAATGTACCATAAATAAACGATATAATGATAAGATGAAAAAAACAG
TGACAGAAAGGAACATAAAA

Downstream 100 bases:

>100_bases
GGTTAAGATGGAAGTTTTTGTTTCACTTTTTCGGCCAGATGCTGATTGTGATCCTGCTGCTTACGGTTATGCTTGTTGCA
TCGTTTTTCTATTTAGACGC

Product: two-component response regulator YvrH involved in cell wall processes YvrG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MENASILIVDDEKAIVDMIKRVLEKEGYRNILDAASAEEAIPVVKANKVDLIVLDVMMGGMSGFEACTLIREYSDAPIFF
LTARSSDADKLSGFAVGADDYITKPFNPLELAARIRAHLKRTYQSKETSSNQTYTYDYFTFSPQNAELIVGGEAVACSAQ
LLQLLQYFCEHPNVVLSKDQIYEKVWGYPSYGDNNTVMVHIRKLREKIERDPSNPEYIVTVRGLGYRFIPNPEGKRS

Sequences:

>Translated_237_residues
MENASILIVDDEKAIVDMIKRVLEKEGYRNILDAASAEEAIPVVKANKVDLIVLDVMMGGMSGFEACTLIREYSDAPIFF
LTARSSDADKLSGFAVGADDYITKPFNPLELAARIRAHLKRTYQSKETSSNQTYTYDYFTFSPQNAELIVGGEAVACSAQ
LLQLLQYFCEHPNVVLSKDQIYEKVWGYPSYGDNNTVMVHIRKLREKIERDPSNPEYIVTVRGLGYRFIPNPEGKRS
>Mature_237_residues
MENASILIVDDEKAIVDMIKRVLEKEGYRNILDAASAEEAIPVVKANKVDLIVLDVMMGGMSGFEACTLIREYSDAPIFF
LTARSSDADKLSGFAVGADDYITKPFNPLELAARIRAHLKRTYQSKETSSNQTYTYDYFTFSPQNAELIVGGEAVACSAQ
LLQLLQYFCEHPNVVLSKDQIYEKVWGYPSYGDNNTVMVHIRKLREKIERDPSNPEYIVTVRGLGYRFIPNPEGKRS

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=36.5638766519824, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=33.4763948497854, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=33.3333333333333, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=31.5555555555556, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=32.6086956521739, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=32.7510917030568, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=30.2222222222222, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=29.5964125560538, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=29.7413793103448, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=30.3030303030303, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=29.7777777777778, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=28.4444444444444, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=28.1938325991189, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=25.531914893617, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YVRH_BACSU (P94504)

Other databases:

- EMBL:   AJ223978
- EMBL:   AL009126
- PIR:   C70047
- RefSeq:   NP_391202.2
- HSSP:   P13792
- ProteinModelPortal:   P94504
- SMR:   P94504
- EnsemblBacteria:   EBBACT00000003380
- GeneID:   935974
- GenomeReviews:   AL009126_GR
- NMPDR:   fig|224308.1.peg.3328
- GenoList:   BSU33220
- GeneTree:   EBGT00070000031966
- HOGENOM:   HBG753323
- ProtClustDB:   CLSK929089
- BioCyc:   BSUB:BSU33221-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- SMART:   SM00448
- SMART:   SM00862

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C; SSF52172 CheY_like

EC number: NA

Molecular weight: Translated: 26680; Mature: 26680

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENASILIVDDEKAIVDMIKRVLEKEGYRNILDAASAEEAIPVVKANKVDLIVLDVMMGG
CCCCEEEEEECCHHHHHHHHHHHHHCCHHHHHHHCCHHHCCCEEECCCCCEEEEEHHHCC
MSGFEACTLIREYSDAPIFFLTARSSDADKLSGFAVGADDYITKPFNPLELAARIRAHLK
CCHHHHHHHHHHCCCCCEEEEEECCCCCHHHCCEEECCCCCCCCCCCHHHHHHHHHHHHH
RTYQSKETSSNQTYTYDYFTFSPQNAELIVGGEAVACSAQLLQLLQYFCEHPNVVLSKDQ
HHHHHCCCCCCCEEEEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCEEECHHH
IYEKVWGYPSYGDNNTVMVHIRKLREKIERDPSNPEYIVTVRGLGYRFIPNPEGKRS
HHHHHCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCEEEEEECCCEEECCCCCCCCC
>Mature Secondary Structure
MENASILIVDDEKAIVDMIKRVLEKEGYRNILDAASAEEAIPVVKANKVDLIVLDVMMGG
CCCCEEEEEECCHHHHHHHHHHHHHCCHHHHHHHCCHHHCCCEEECCCCCEEEEEHHHCC
MSGFEACTLIREYSDAPIFFLTARSSDADKLSGFAVGADDYITKPFNPLELAARIRAHLK
CCHHHHHHHHHHCCCCCEEEEEECCCCCHHHCCEEECCCCCCCCCCCHHHHHHHHHHHHH
RTYQSKETSSNQTYTYDYFTFSPQNAELIVGGEAVACSAQLLQLLQYFCEHPNVVLSKDQ
HHHHHCCCCCCCEEEEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCEEECHHH
IYEKVWGYPSYGDNNTVMVHIRKLREKIERDPSNPEYIVTVRGLGYRFIPNPEGKRS
HHHHHCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCEEEEEECCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377