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The map label for this gene is yvrG

Identifier: 255767757

GI number: 255767757

Start: 3406614

End: 3408356

Strand: Reverse

Name: yvrG

Synonym: BSU33210

Alternate gene names: 255767757

Gene position: 3408356-3406614 (Counterclockwise)

Preceding gene: 255767758

Following gene: 16080373

Centisome position: 80.85

GC content: 42.34

Gene sequence:

>1743_bases
ATGAGGTTAAGATGGAAGTTTTTGTTTCACTTTTTCGGCCAGATGCTGATTGTGATCCTGCTGCTTACGGTTATGCTTGT
TGCATCGTTTTTCTATTTAGACGCCCGTTTTAGCGATGCGGAATCCAATTCAGGGCTGACGAAAGCAACGACCGACACAC
TTGAGGCATATCTCGATGTAAACGAAGACGGGACATGGGAAGTGGATAATTTCCTGAAGAAATCTGTTGATAAACAGCAC
GGCTGGATGCAAATCATTGATTCGGAAGGAAACACTGATTATTCCTACGGCGTGCCAAAAGACGTGCCGGGCACCTATAC
CAAGAAAGAGCTTTTGTCTATTTATAAAACCAAAAAGCTTCATAACTATAAACTGAATTATTGGGCCATCAATATTGAAG
ATAAGTCGTATCTTCTATTGTCCGGCTGGAAATCAAAAAGTGAACAGCTCCTGACTTCCGTTGAAAAGCGTGAACAAAAG
ATAGACTCACTAGCGCACTATAAGTCTAGTACCATCGACTATATTAAACGGAAAAAAGGCGCCATTTACCTGTTAGACAG
CAATGGAAAGATTCTCGACAGCATCAACAGCACAAAAAGCGAGAGAAAAACGATGAACCAGCTGGAGCTGCTTAAATACA
GCTCTAAGCCTTGGAACTATAAGCGGGAAATTTCCGTTAAGATCCTCAATAAAGACAGATGGATGGTCGCTACGGTGCCG
AACCCAGTCTATGTAACCGATCAGGAGTTTAACAAATCATTCCTGAAGGTTGTATTAAAAGCGATGTTTCTCGTGATGGC
CGTTTTGTTCATGTATATCATTTGGATGACCGTTTGGTATATGTTCCGATTCGGGCTGCCGATTTTTCACACGATTAGAT
GGCTGGTCAATCTGTCAAAAGGGAAGCTTGAGGAGCCCAGAAACCGGGAAGGCCGTCCTGTCAGCAAAAATAAAAAGGGA
AAAATCAAACAGCCGTACCGCTTCTTCGGTGAGATATTTGAATCAATGGATCAGCTGACTGAAACGCTGAGAAGGGATAA
AAGAAACAGAGAAAAAATCCAGGCGACAAGGGAAGAATGGATTGCCGGTTTGTCACATGACTTAAAAACACCGCTCAGCA
GCATTTACGGCTACAGCATGATGCTCGAGTCGAAGCAGTATGACTGGTCGCCGGAAGAAGTGAAAGAAATGGGGCAGGTT
GTCAGAGAAAAATCTGAATACATGTCTAAGCTGATTGAAGACTTAAATTTAACGTATCGCCTGAAAAATGATGCTCTTCC
TATTGAGAGAAAGCTCACTAGCCTTATCCCGTTTTTTAAAAATGTCATTGAGGATTTTAAGAAAAATCCGTTTTCTGAAG
GCTATGATATCTCGTTTGTATCCAAAGAAGAGCATATTGAATTTGCCCTTGATGAAGCGTGGTTCAGGCGCATATTAGAA
AACCTCCTTGGGAATGCCGTGAAGCACAACGGCAAAGGAACAGAGATTCAAGTCATTCTGGAGCAAACAAAAAATCATAT
TTCTTTAAAAGTGAAGGACAATGGGAAAGGAATGGATGAAGAAACGATCACCCATTTGTTTAACCGCTACTACAGAGGGA
CGAACACAAAAGATTCAACTGCCGGAACGGGTCTCGGGCTCGCGATTGCCAAGGAGCTTGTCCATCTGCATAACGGAACG
ATCCATGTGAACAGCAGAACGAACATTGGAACGGTCATTACCATCCTTTTTAAAAAACAATAA

Upstream 100 bases:

>100_bases
TTAGGGAGAAGATTGAGCGCGATCCGAGCAATCCGGAGTATATTGTAACCGTTCGAGGTCTCGGCTATCGTTTTATCCCA
AATCCTGAAGGCAAGCGGTC

Downstream 100 bases:

>100_bases
ACATCAAGTGGTTTGGACACCTCTTTGCCGGGAATAACAATATATAGACTGAAGCTAAAGAGGTGTAACACATGGATGCA
GTATTGGAAGCAGACACTCG

Product: two-component sensor histidine kinase YvrG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 580; Mature: 580

Protein sequence:

>580_residues
MRLRWKFLFHFFGQMLIVILLLTVMLVASFFYLDARFSDAESNSGLTKATTDTLEAYLDVNEDGTWEVDNFLKKSVDKQH
GWMQIIDSEGNTDYSYGVPKDVPGTYTKKELLSIYKTKKLHNYKLNYWAINIEDKSYLLLSGWKSKSEQLLTSVEKREQK
IDSLAHYKSSTIDYIKRKKGAIYLLDSNGKILDSINSTKSERKTMNQLELLKYSSKPWNYKREISVKILNKDRWMVATVP
NPVYVTDQEFNKSFLKVVLKAMFLVMAVLFMYIIWMTVWYMFRFGLPIFHTIRWLVNLSKGKLEEPRNREGRPVSKNKKG
KIKQPYRFFGEIFESMDQLTETLRRDKRNREKIQATREEWIAGLSHDLKTPLSSIYGYSMMLESKQYDWSPEEVKEMGQV
VREKSEYMSKLIEDLNLTYRLKNDALPIERKLTSLIPFFKNVIEDFKKNPFSEGYDISFVSKEEHIEFALDEAWFRRILE
NLLGNAVKHNGKGTEIQVILEQTKNHISLKVKDNGKGMDEETITHLFNRYYRGTNTKDSTAGTGLGLAIAKELVHLHNGT
IHVNSRTNIGTVITILFKKQ

Sequences:

>Translated_580_residues
MRLRWKFLFHFFGQMLIVILLLTVMLVASFFYLDARFSDAESNSGLTKATTDTLEAYLDVNEDGTWEVDNFLKKSVDKQH
GWMQIIDSEGNTDYSYGVPKDVPGTYTKKELLSIYKTKKLHNYKLNYWAINIEDKSYLLLSGWKSKSEQLLTSVEKREQK
IDSLAHYKSSTIDYIKRKKGAIYLLDSNGKILDSINSTKSERKTMNQLELLKYSSKPWNYKREISVKILNKDRWMVATVP
NPVYVTDQEFNKSFLKVVLKAMFLVMAVLFMYIIWMTVWYMFRFGLPIFHTIRWLVNLSKGKLEEPRNREGRPVSKNKKG
KIKQPYRFFGEIFESMDQLTETLRRDKRNREKIQATREEWIAGLSHDLKTPLSSIYGYSMMLESKQYDWSPEEVKEMGQV
VREKSEYMSKLIEDLNLTYRLKNDALPIERKLTSLIPFFKNVIEDFKKNPFSEGYDISFVSKEEHIEFALDEAWFRRILE
NLLGNAVKHNGKGTEIQVILEQTKNHISLKVKDNGKGMDEETITHLFNRYYRGTNTKDSTAGTGLGLAIAKELVHLHNGT
IHVNSRTNIGTVITILFKKQ
>Mature_580_residues
MRLRWKFLFHFFGQMLIVILLLTVMLVASFFYLDARFSDAESNSGLTKATTDTLEAYLDVNEDGTWEVDNFLKKSVDKQH
GWMQIIDSEGNTDYSYGVPKDVPGTYTKKELLSIYKTKKLHNYKLNYWAINIEDKSYLLLSGWKSKSEQLLTSVEKREQK
IDSLAHYKSSTIDYIKRKKGAIYLLDSNGKILDSINSTKSERKTMNQLELLKYSSKPWNYKREISVKILNKDRWMVATVP
NPVYVTDQEFNKSFLKVVLKAMFLVMAVLFMYIIWMTVWYMFRFGLPIFHTIRWLVNLSKGKLEEPRNREGRPVSKNKKG
KIKQPYRFFGEIFESMDQLTETLRRDKRNREKIQATREEWIAGLSHDLKTPLSSIYGYSMMLESKQYDWSPEEVKEMGQV
VREKSEYMSKLIEDLNLTYRLKNDALPIERKLTSLIPFFKNVIEDFKKNPFSEGYDISFVSKEEHIEFALDEAWFRRILE
NLLGNAVKHNGKGTEIQVILEQTKNHISLKVKDNGKGMDEETITHLFNRYYRGTNTKDSTAGTGLGLAIAKELVHLHNGT
IHVNSRTNIGTVITILFKKQ

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon. Probably activates yv

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain

Homologues:

Organism=Escherichia coli, GI1788393, Length=264, Percent_Identity=26.5151515151515, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI145693157, Length=240, Percent_Identity=24.1666666666667, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1786912, Length=243, Percent_Identity=27.5720164609054, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786600, Length=241, Percent_Identity=27.8008298755187, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1786783, Length=318, Percent_Identity=21.3836477987421, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788713, Length=250, Percent_Identity=27.6, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1790861, Length=412, Percent_Identity=25.7281553398058, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=24.2553191489362, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789149, Length=257, Percent_Identity=23.7354085603113, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789808, Length=258, Percent_Identity=26.7441860465116, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1787894, Length=233, Percent_Identity=25.7510729613734, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787374, Length=317, Percent_Identity=21.7665615141956, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1788549, Length=249, Percent_Identity=26.1044176706827, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI87082128, Length=220, Percent_Identity=23.6363636363636, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788279, Length=205, Percent_Identity=24.390243902439, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YVRG_BACSU (O34989)

Other databases:

- EMBL:   AJ223978
- EMBL:   AL009126
- PIR:   B70047
- RefSeq:   NP_391201.2
- ProteinModelPortal:   O34989
- SMR:   O34989
- EnsemblBacteria:   EBBACT00000002438
- GeneID:   935985
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU33210
- NMPDR:   fig|224308.1.peg.3327
- GenoList:   BSU33210
- GeneTree:   EBGT00070000032037
- HOGENOM:   HBG338310
- ProtClustDB:   CLSK873611
- BioCyc:   BSUB:BSU33210-MONOMER
- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- Gene3D:   G3DSA:3.30.565.10
- PRINTS:   PR00344
- SMART:   SM00387
- SMART:   SM00388

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; SSF55874 ATP_bd_ATPase; SSF47384 His_kin_homodim

EC number: =2.7.13.3

Molecular weight: Translated: 67800; Mature: 67800

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x117433e8)-; HASH(0x1246ee4c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLRWKFLFHFFGQMLIVILLLTVMLVASFFYLDARFSDAESNSGLTKATTDTLEAYLDV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHEEC
NEDGTWEVDNFLKKSVDKQHGWMQIIDSEGNTDYSYGVPKDVPGTYTKKELLSIYKTKKL
CCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
HNYKLNYWAINIEDKSYLLLSGWKSKSEQLLTSVEKREQKIDSLAHYKSSTIDYIKRKKG
CCEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AIYLLDSNGKILDSINSTKSERKTMNQLELLKYSSKPWNYKREISVKILNKDRWMVATVP
EEEEECCCCCEEHHHHCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCEEEEECC
NPVYVTDQEFNKSFLKVVLKAMFLVMAVLFMYIIWMTVWYMFRFGLPIFHTIRWLVNLSK
CCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
GKLEEPRNREGRPVSKNKKGKIKQPYRFFGEIFESMDQLTETLRRDKRNREKIQATREEW
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAGLSHDLKTPLSSIYGYSMMLESKQYDWSPEEVKEMGQVVREKSEYMSKLIEDLNLTYR
HHHHHHHHHHHHHHHCCHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LKNDALPIERKLTSLIPFFKNVIEDFKKNPFSEGYDISFVSKEEHIEFALDEAWFRRILE
ECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHH
NLLGNAVKHNGKGTEIQVILEQTKNHISLKVKDNGKGMDEETITHLFNRYYRGTNTKDST
HHHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCC
AGTGLGLAIAKELVHLHNGTIHVNSRTNIGTVITILFKKQ
CCCCHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEEECH
>Mature Secondary Structure
MRLRWKFLFHFFGQMLIVILLLTVMLVASFFYLDARFSDAESNSGLTKATTDTLEAYLDV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHEEC
NEDGTWEVDNFLKKSVDKQHGWMQIIDSEGNTDYSYGVPKDVPGTYTKKELLSIYKTKKL
CCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
HNYKLNYWAINIEDKSYLLLSGWKSKSEQLLTSVEKREQKIDSLAHYKSSTIDYIKRKKG
CCEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AIYLLDSNGKILDSINSTKSERKTMNQLELLKYSSKPWNYKREISVKILNKDRWMVATVP
EEEEECCCCCEEHHHHCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCEEEEECC
NPVYVTDQEFNKSFLKVVLKAMFLVMAVLFMYIIWMTVWYMFRFGLPIFHTIRWLVNLSK
CCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
GKLEEPRNREGRPVSKNKKGKIKQPYRFFGEIFESMDQLTETLRRDKRNREKIQATREEW
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAGLSHDLKTPLSSIYGYSMMLESKQYDWSPEEVKEMGQVVREKSEYMSKLIEDLNLTYR
HHHHHHHHHHHHHHHCCHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LKNDALPIERKLTSLIPFFKNVIEDFKKNPFSEGYDISFVSKEEHIEFALDEAWFRRILE
ECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHH
NLLGNAVKHNGKGTEIQVILEQTKNHISLKVKDNGKGMDEETITHLFNRYYRGTNTKDST
HHHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCC
AGTGLGLAIAKELVHLHNGTIHVNSRTNIGTVITILFKKQ
CCCCHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEEECH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377