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The map label for this gene is mraY

Identifier: 255767348

GI number: 255767348

Start: 1587926

End: 1588900

Strand: Direct

Name: mraY

Synonym: BSU15190

Alternate gene names: 255767348

Gene position: 1587926-1588900 (Clockwise)

Preceding gene: 16078582

Following gene: 16078584

Centisome position: 37.67

GC content: 42.77

Gene sequence:

>975_bases
ATGCTTGAGCAAGTCATTCTGTTTACAATTTTAATGGGGTTTTTAATTAGTGTTCTGCTCTCTCCGATTCTTATTCCGTT
TTTAAGAAGATTAAAATTCGGCCAGAGTATTAGAGAAGAAGGACCGAAATCACATCAGAAAAAATCAGGGACACCGACAA
TGGGCGGGGTCATGATCATACTTTCTATCATAGTGACAACAATTGTTATGACACAGAAGTTTTCAGAAATAAGCCCCGAA
ATGGTGCTGCTTCTGTTTGTTACGCTAGGCTACGGTTTGCTTGGCTTTTTAGATGATTACATCAAGGTTGTCATGAAGCG
CAATCTTGGATTGACATCAAAGCAAAAGCTGATCGGACAAATTATTATTGCGGTTGTATTTTACGCCGTGTATCATTACT
ACAATTTTGCGACGGATATTCGCATTCCTGGAACTGACTTATCATTTGATCTTGGCTGGGCTTACTTTATCCTTGTGCTC
TTTATGCTAGTCGGCGGATCAAACGCAGTTAACCTGACTGACGGCCTTGACGGGTTATTATCCGGTACTGCGGCGATTGC
CTTTGGCGCCTTTGCCATTCTGGCATGGAATCAGTCTCAATATGACGTAGCGATTTTCTCAGTTGCCGTTGTCGGTGCAG
TTCTGGGCTTCCTTGTATTTAATGCTCATCCGGCCAAAGTTTTTATGGGAGATACGGGATCGCTTGCATTGGGAGGAGCC
ATCGTTACCATTGCCATTTTAACGAAATTAGAGATCCTGCTGGTTATCATCGGCGGTGTATTCGTTATCGAGACATTATC
CGTTATTTTGCAGGTCATCAGCTTTAAAACGACAGGTAAACGAATCTTTAAAATGAGTCCGCTTCATCACCATTATGAGC
TTGTCGGCTGGTCTGAATGGAGAGTAGTCGTGACGTTTTGGGCTGCGGGACTTTTGCTTGCCGTTTTAGGAATTTACATC
GAGGTGTGGTTATAA

Upstream 100 bases:

>100_bases
TACTGAATAATGGAGCTTGAAAAGATTTTTCATATGGAAAAAAATCATGAATATGATAACTACGTATGTCGTTTGAAAGA
AACAGGAGGAGAAAAGGACA

Downstream 100 bases:

>100_bases
GTGGAAAATGATCAATTTTTACAGAAACAGCATTTTTTAATCCTTGGGCTTGCGAAAAGCGGATATGCGGCGGCCTCCAT
TCTTCATGAAAAAGGCATTT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MLEQVILFTILMGFLISVLLSPILIPFLRRLKFGQSIREEGPKSHQKKSGTPTMGGVMIILSIIVTTIVMTQKFSEISPE
MVLLLFVTLGYGLLGFLDDYIKVVMKRNLGLTSKQKLIGQIIIAVVFYAVYHYYNFATDIRIPGTDLSFDLGWAYFILVL
FMLVGGSNAVNLTDGLDGLLSGTAAIAFGAFAILAWNQSQYDVAIFSVAVVGAVLGFLVFNAHPAKVFMGDTGSLALGGA
IVTIAILTKLEILLVIIGGVFVIETLSVILQVISFKTTGKRIFKMSPLHHHYELVGWSEWRVVVTFWAAGLLLAVLGIYI
EVWL

Sequences:

>Translated_324_residues
MLEQVILFTILMGFLISVLLSPILIPFLRRLKFGQSIREEGPKSHQKKSGTPTMGGVMIILSIIVTTIVMTQKFSEISPE
MVLLLFVTLGYGLLGFLDDYIKVVMKRNLGLTSKQKLIGQIIIAVVFYAVYHYYNFATDIRIPGTDLSFDLGWAYFILVL
FMLVGGSNAVNLTDGLDGLLSGTAAIAFGAFAILAWNQSQYDVAIFSVAVVGAVLGFLVFNAHPAKVFMGDTGSLALGGA
IVTIAILTKLEILLVIIGGVFVIETLSVILQVISFKTTGKRIFKMSPLHHHYELVGWSEWRVVVTFWAAGLLLAVLGIYI
EVWL
>Mature_324_residues
MLEQVILFTILMGFLISVLLSPILIPFLRRLKFGQSIREEGPKSHQKKSGTPTMGGVMIILSIIVTTIVMTQKFSEISPE
MVLLLFVTLGYGLLGFLDDYIKVVMKRNLGLTSKQKLIGQIIIAVVFYAVYHYYNFATDIRIPGTDLSFDLGWAYFILVL
FMLVGGSNAVNLTDGLDGLLSGTAAIAFGAFAILAWNQSQYDVAIFSVAVVGAVLGFLVFNAHPAKVFMGDTGSLALGGA
IVTIAILTKLEILLVIIGGVFVIETLSVILQVISFKTTGKRIFKMSPLHHHYELVGWSEWRVVVTFWAAGLLLAVLGIYI
EVWL

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=329, Percent_Identity=46.5045592705167, Blast_Score=249, Evalue=1e-67,
Organism=Escherichia coli, GI1790218, Length=97, Percent_Identity=35.0515463917526, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 35527; Mature: 35527

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQVILFTILMGFLISVLLSPILIPFLRRLKFGQSIREEGPKSHQKKSGTPTMGGVMII
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHCCCCCCCHHHHHHH
LSIIVTTIVMTQKFSEISPEMVLLLFVTLGYGLLGFLDDYIKVVMKRNLGLTSKQKLIGQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
IIIAVVFYAVYHYYNFATDIRIPGTDLSFDLGWAYFILVLFMLVGGSNAVNLTDGLDGLL
HHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHH
SGTAAIAFGAFAILAWNQSQYDVAIFSVAVVGAVLGFLVFNAHPAKVFMGDTGSLALGGA
HHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHH
IVTIAILTKLEILLVIIGGVFVIETLSVILQVISFKTTGKRIFKMSPLHHHYELVGWSEW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEECCCHHHHHEECHHHH
RVVVTFWAAGLLLAVLGIYIEVWL
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLEQVILFTILMGFLISVLLSPILIPFLRRLKFGQSIREEGPKSHQKKSGTPTMGGVMII
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHCCCCCCCHHHHHHH
LSIIVTTIVMTQKFSEISPEMVLLLFVTLGYGLLGFLDDYIKVVMKRNLGLTSKQKLIGQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
IIIAVVFYAVYHYYNFATDIRIPGTDLSFDLGWAYFILVLFMLVGGSNAVNLTDGLDGLL
HHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHH
SGTAAIAFGAFAILAWNQSQYDVAIFSVAVVGAVLGFLVFNAHPAKVFMGDTGSLALGGA
HHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHH
IVTIAILTKLEILLVIIGGVFVIETLSVILQVISFKTTGKRIFKMSPLHHHYELVGWSEW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEECCCHHHHHEECHHHH
RVVVTFWAAGLLLAVLGIYIEVWL
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA