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The map label for this gene is nrdR

Identifier: 239618391

GI number: 239618391

Start: 2158490

End: 2158966

Strand: Direct

Name: nrdR

Synonym: Kole_2031

Alternate gene names: 239618391

Gene position: 2158490-2158966 (Clockwise)

Preceding gene: 239618390

Following gene: 239618392

Centisome position: 93.76

GC content: 40.67

Gene sequence:

>477_bases
ATGAAATGCCCGTTTTGTAACAGCGAAGAAACGAGAGTAATCGATACACGACTCACAGATGACGGTCATGTTGTTCGTAG
ACGAAGAGAGTGTGAGCATTGTGGAGGACGATTCACAACTTACGAACGTTTTGAACAAAAACCGATTTTTGTGGTAAAAA
AAGGTGGTCAACGCGAAAGATTTGATAGAAATAAAGTTTTGAATGGTATTTTGAAAGCCTGTGAAAAGAGACCTGTTTCC
ATAGAAGAAATAGAGAACATGTCAAGCGAGATCGAGCAGGAGGTCTTGCGATCCGGCAAGGCTGAAATTAGCTCGAAGGA
AATAGGTGAGATGGTTATGGAAAAATTGAAAAGAAAAGATCGTGTTGCGTACGTCAGGTTTGCATCAGTTTACAAAGAAT
TCAGAGATTTGGACCATTTCATGGATATAATAAGGGAGCTAAAGGACGAACTGAAGAAGCGCGACAGGAGGGATTAA

Upstream 100 bases:

>100_bases
CGCGAACTTGGCGAACTTATGGATCCTCCCATGAGTAAGTCGGCTGTTTATAATAGGTTCAAAAAGATAATCAAAATCGC
GGAGTCGCTGGGGGGATTAG

Downstream 100 bases:

>100_bases
GGTGTCTAAAAAGAATGTGATTTACCTTACGAAAGAAGGTTATGAAAACCTGAAAAATGAATTGAATACGCTGAGAAAGA
AGTTGATGTACGAGGTTGCA

Product: ATP-cone domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MKCPFCNSEETRVIDTRLTDDGHVVRRRRECEHCGGRFTTYERFEQKPIFVVKKGGQRERFDRNKVLNGILKACEKRPVS
IEEIENMSSEIEQEVLRSGKAEISSKEIGEMVMEKLKRKDRVAYVRFASVYKEFRDLDHFMDIIRELKDELKKRDRRD

Sequences:

>Translated_158_residues
MKCPFCNSEETRVIDTRLTDDGHVVRRRRECEHCGGRFTTYERFEQKPIFVVKKGGQRERFDRNKVLNGILKACEKRPVS
IEEIENMSSEIEQEVLRSGKAEISSKEIGEMVMEKLKRKDRVAYVRFASVYKEFRDLDHFMDIIRELKDELKKRDRRD
>Mature_158_residues
MKCPFCNSEETRVIDTRLTDDGHVVRRRRECEHCGGRFTTYERFEQKPIFVVKKGGQRERFDRNKVLNGILKACEKRPVS
IEEIENMSSEIEQEVLRSGKAEISSKEIGEMVMEKLKRKDRVAYVRFASVYKEFRDLDHFMDIIRELKDELKKRDRRD

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=149, Percent_Identity=46.9798657718121, Blast_Score=135, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_KOSOT (C5CHN3)

Other databases:

- EMBL:   CP001634
- RefSeq:   YP_002941713.1
- GeneID:   7967629
- GenomeReviews:   CP001634_GR
- KEGG:   kol:Kole_2031
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 18878; Mature: 18878

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCPFCNSEETRVIDTRLTDDGHVVRRRRECEHCGGRFTTYERFEQKPIFVVKKGGQRER
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEECCCCHHH
FDRNKVLNGILKACEKRPVSIEEIENMSSEIEQEVLRSGKAEISSKEIGEMVMEKLKRKD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHH
RVAYVRFASVYKEFRDLDHFMDIIRELKDELKKRDRRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKCPFCNSEETRVIDTRLTDDGHVVRRRRECEHCGGRFTTYERFEQKPIFVVKKGGQRER
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEECCCCHHH
FDRNKVLNGILKACEKRPVSIEEIENMSSEIEQEVLRSGKAEISSKEIGEMVMEKLKRKD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHH
RVAYVRFASVYKEFRDLDHFMDIIRELKDELKKRDRRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA