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The map label for this gene is glcK [H]

Identifier: 239618233

GI number: 239618233

Start: 2005817

End: 2006761

Strand: Reverse

Name: glcK [H]

Synonym: Kole_1870

Alternate gene names: 239618233

Gene position: 2006761-2005817 (Counterclockwise)

Preceding gene: 239618234

Following gene: 239618231

Centisome position: 87.17

GC content: 42.43

Gene sequence:

>945_bases
ATGGGATTAGTTATTGGCATCGATCTTGGAGGTACAGAAACTAAAATAGGTTTGGTAGATGAACATGGAAAGATTCTGAA
CAAAACAACTATTCCCACCCTGGTTTCCAGAGGCCGAGAAGATGTGGTGGCACGTATTGCCAATAGTATACATAATATTC
TAGACATCGCAAACGAGAAGGACAAAGTGCTTGCCATAGGAATTGGTTCCCCTGGATCAATAGACAGAGATAGCGGAAAG
GTCTTATTTTCACCGAATTTTCCGGATTGGAGAGATTTTCCCCTTGCTTCTATGATAAGAAAACATACAGGATTGGAAAC
TTTTATTGAAAACGATGCCAACGCTTTTATCCTTGGTGAATGGGCTTTTGGGAAATATAAAGGTAGTAAACATATGATAG
GACTCACTATCGGAACAGGAATTGGTAGCGGAGTCATTTCTCACGGTCAACTAATAACCGGCCACAACGGTTATGCTGTG
GAACTCGGACATATTATTGTGGAGCCAAACGGTCCACTCTGTGGCTGTGGTTCACATGGCTGTTTGGAAGCAGTAGCATC
CGCAACGGCAATTGTGCGTTTTGCTCACGAATATAGAAAGCGTTTTCCTGATTCTGCGATTTTCTCATCTGAAAAAATAG
AGGCAAAAACCGTTATAGATGCCGCAAAAAGCGGAGATGAACTTGGAAAAATTATTTTTGATAGGTTTATTGATGCTCTT
GCACGTGGAATAGGTGGATTCATTCACACGTTCAACCCGGAAGTAGTAATAGTCGGCGGAGGTGTGAGTAAAGCGGGAGA
CTTTCTACTAAAAAACCTTAGAGAACGGGTTGATAGATACGTAATGACTTCATTCAAGGGAACGGCCAAAGTAGATCTAA
GTGATCTGGTGGAAGATGCCGGAATAAAAGGGGCCGCTTCCATCGTTTTCTATCGCAAGAGGTGA

Upstream 100 bases:

>100_bases
TTAAAAGTCATTGTAGATAAAATGAAAACCACTAAATCCAACGAGGAATTTCTTGATCTGATAGATCTCGAAAAAAGCAG
ATATTGAAAGGTAGGATGAA

Downstream 100 bases:

>100_bases
TTTTTTCTCAAACGCTGGGTAAGTATGTGAGCCTGCCTTGTTGGTTCTGGTAACCTATATTTTCCTGTATATTTTAGGGT
TAATGACATAGCGGTATCAA

Product: ROK family protein

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MGLVIGIDLGGTETKIGLVDEHGKILNKTTIPTLVSRGREDVVARIANSIHNILDIANEKDKVLAIGIGSPGSIDRDSGK
VLFSPNFPDWRDFPLASMIRKHTGLETFIENDANAFILGEWAFGKYKGSKHMIGLTIGTGIGSGVISHGQLITGHNGYAV
ELGHIIVEPNGPLCGCGSHGCLEAVASATAIVRFAHEYRKRFPDSAIFSSEKIEAKTVIDAAKSGDELGKIIFDRFIDAL
ARGIGGFIHTFNPEVVIVGGGVSKAGDFLLKNLRERVDRYVMTSFKGTAKVDLSDLVEDAGIKGAASIVFYRKR

Sequences:

>Translated_314_residues
MGLVIGIDLGGTETKIGLVDEHGKILNKTTIPTLVSRGREDVVARIANSIHNILDIANEKDKVLAIGIGSPGSIDRDSGK
VLFSPNFPDWRDFPLASMIRKHTGLETFIENDANAFILGEWAFGKYKGSKHMIGLTIGTGIGSGVISHGQLITGHNGYAV
ELGHIIVEPNGPLCGCGSHGCLEAVASATAIVRFAHEYRKRFPDSAIFSSEKIEAKTVIDAAKSGDELGKIIFDRFIDAL
ARGIGGFIHTFNPEVVIVGGGVSKAGDFLLKNLRERVDRYVMTSFKGTAKVDLSDLVEDAGIKGAASIVFYRKR
>Mature_313_residues
GLVIGIDLGGTETKIGLVDEHGKILNKTTIPTLVSRGREDVVARIANSIHNILDIANEKDKVLAIGIGSPGSIDRDSGKV
LFSPNFPDWRDFPLASMIRKHTGLETFIENDANAFILGEWAFGKYKGSKHMIGLTIGTGIGSGVISHGQLITGHNGYAVE
LGHIIVEPNGPLCGCGSHGCLEAVASATAIVRFAHEYRKRFPDSAIFSSEKIEAKTVIDAAKSGDELGKIIFDRFIDALA
RGIGGFIHTFNPEVVIVGGGVSKAGDFLLKNLRERVDRYVMTSFKGTAKVDLSDLVEDAGIKGAASIVFYRKR

Specific function: May Be A Regulator In Specific Sugar Metabolism. May Influence The Rate Of Glucose Uptake Or Glycolysis In Cells In The Rich Medium. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI190014632, Length=269, Percent_Identity=33.0855018587361, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI298566325, Length=269, Percent_Identity=33.0855018587361, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI298566315, Length=269, Percent_Identity=33.0855018587361, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI4885285, Length=269, Percent_Identity=33.0855018587361, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI298566312, Length=119, Percent_Identity=37.8151260504202, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1787878, Length=248, Percent_Identity=29.0322580645161, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1786891, Length=313, Percent_Identity=29.073482428115, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787363, Length=318, Percent_Identity=26.1006289308176, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI87081733, Length=324, Percent_Identity=26.8518518518519, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082230, Length=269, Percent_Identity=31.5985130111524, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082127, Length=213, Percent_Identity=24.4131455399061, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790522, Length=286, Percent_Identity=24.8251748251748, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 33660; Mature: 33529

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLVIGIDLGGTETKIGLVDEHGKILNKTTIPTLVSRGREDVVARIANSIHNILDIANEK
CCEEEEEECCCCCEEEEEECCCCCHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
DKVLAIGIGSPGSIDRDSGKVLFSPNFPDWRDFPLASMIRKHTGLETFIENDANAFILGE
CCEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHCCHHHHHCCCCCEEEEEE
WAFGKYKGSKHMIGLTIGTGIGSGVISHGQLITGHNGYAVELGHIIVEPNGPLCGCGSHG
ECCCEECCCCEEEEEEECCCCCCCHHCCCEEEECCCCEEEEEEEEEECCCCCEECCCCHH
CLEAVASATAIVRFAHEYRKRFPDSAIFSSEKIEAKTVIDAAKSGDELGKIIFDRFIDAL
HHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHH
ARGIGGFIHTFNPEVVIVGGGVSKAGDFLLKNLRERVDRYVMTSFKGTAKVDLSDLVEDA
HHHHCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHC
GIKGAASIVFYRKR
CCCCEEEEEEEECC
>Mature Secondary Structure 
GLVIGIDLGGTETKIGLVDEHGKILNKTTIPTLVSRGREDVVARIANSIHNILDIANEK
CEEEEEECCCCCEEEEEECCCCCHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
DKVLAIGIGSPGSIDRDSGKVLFSPNFPDWRDFPLASMIRKHTGLETFIENDANAFILGE
CCEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHCCHHHHHCCCCCEEEEEE
WAFGKYKGSKHMIGLTIGTGIGSGVISHGQLITGHNGYAVELGHIIVEPNGPLCGCGSHG
ECCCEECCCCEEEEEEECCCCCCCHHCCCEEEECCCCEEEEEEEEEECCCCCEECCCCHH
CLEAVASATAIVRFAHEYRKRFPDSAIFSSEKIEAKTVIDAAKSGDELGKIIFDRFIDAL
HHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHH
ARGIGGFIHTFNPEVVIVGGGVSKAGDFLLKNLRERVDRYVMTSFKGTAKVDLSDLVEDA
HHHHCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHC
GIKGAASIVFYRKR
CCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]