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The map label for this gene is iolE [H]

Identifier: 239617378

GI number: 239617378

Start: 1043261

End: 1044157

Strand: Reverse

Name: iolE [H]

Synonym: Kole_0988

Alternate gene names: 239617378

Gene position: 1044157-1043261 (Counterclockwise)

Preceding gene: 239617379

Following gene: 239617377

Centisome position: 45.36

GC content: 44.37

Gene sequence:

>897_bases
GTGGTCGTAAGAGAGGATATAGGGTTAGGAATTGCTCCGATTGGATGGACCAACGACGACATGCCAGAACTTGGTGGAGA
TATTCCTTTTGAACAATGCATCGACGAAATGGCAGAAGCAAAATTTGAAGGGTGTGAGGTTGGAAACAAATTCCCAAGAG
ATCCTGAGGTATTAAGAGCTGCTCTTGAACCGAGAGGCCTTCAGGTAGCCAGCGCCTGGTTCAGCACCTTCTTTACCACC
AAAGATCCCGAAGAAACCTATACTGCCTTTCTGAAACACCGCGACTTTCTCCATGCAATGGGCGCAAAAGTTATTGTCGT
TTCTGAGACTGGAAAATCTATTCAGGGGGAGATAAACACCCCCCTGCACAGCGCAAAACCTATCTTCAGTGACATGGATT
GGAAAAAACTGGTGGATGGACTTCATGAATTGGGAAAACTGGCTGCGGAAAAAGGTATGAAAATTGTTTTCCACCATCAC
ATGGGTACGGGCGTTCAGACTTACGAAGAAATCCGAAAACTCATGGAACTCACTGATCCAGAACTCGTTTACCTCCTTGT
AGATACCGGTCACATGGTCTTCGCTGGTGGAGATCCTGTTGAATTAATAAAAGAGTTTGGCCCAAGAATTAAACACGTTC
ATTTCAAAGATTTACGAAAAGACGTAATGGAACGCTCTTTCAAAGATGATCTTAGTTTTCTAAATTCTGTTAAACTCGGG
GTTTTCACGGTCCCCGGCGACGGAACGATTGATTTTGTTCCAATCGTAAAAGCACTGGATGAAATAGATTACAAGGGCTG
GATTATTGTCGAAGCCGAACAGGATCCGAAGCTTGCGCCACCACTTGAATACGCAATAAAAGCCAGGAATTATCTATCCA
GTGTACTGGGATTTTAG

Upstream 100 bases:

>100_bases
GTTGCAGAGGTTTCAGAAAGTGATACCGTAAGGAAAGCCTTTGAAGAAAACCAGAAATACATGAAGAAAGCCAGAAAATG
GTAATCGAGGGGGAGTTCTT

Downstream 100 bases:

>100_bases
GAGGAGAAAGATATGGCGAAGAAAAGCAAAGTGAAGATAGGGGTTATAGGTGCCGGGAGAATCGGAAAGATACATATCGA
AAACCTCGTTAAAAATGTTC

Product: Myo-inosose-2 dehydratase

Products: NA

Alternate protein names: 2-keto-myo-inositol dehydratase; 2KMI dehydratase [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MVVREDIGLGIAPIGWTNDDMPELGGDIPFEQCIDEMAEAKFEGCEVGNKFPRDPEVLRAALEPRGLQVASAWFSTFFTT
KDPEETYTAFLKHRDFLHAMGAKVIVVSETGKSIQGEINTPLHSAKPIFSDMDWKKLVDGLHELGKLAAEKGMKIVFHHH
MGTGVQTYEEIRKLMELTDPELVYLLVDTGHMVFAGGDPVELIKEFGPRIKHVHFKDLRKDVMERSFKDDLSFLNSVKLG
VFTVPGDGTIDFVPIVKALDEIDYKGWIIVEAEQDPKLAPPLEYAIKARNYLSSVLGF

Sequences:

>Translated_298_residues
MVVREDIGLGIAPIGWTNDDMPELGGDIPFEQCIDEMAEAKFEGCEVGNKFPRDPEVLRAALEPRGLQVASAWFSTFFTT
KDPEETYTAFLKHRDFLHAMGAKVIVVSETGKSIQGEINTPLHSAKPIFSDMDWKKLVDGLHELGKLAAEKGMKIVFHHH
MGTGVQTYEEIRKLMELTDPELVYLLVDTGHMVFAGGDPVELIKEFGPRIKHVHFKDLRKDVMERSFKDDLSFLNSVKLG
VFTVPGDGTIDFVPIVKALDEIDYKGWIIVEAEQDPKLAPPLEYAIKARNYLSSVLGF
>Mature_298_residues
MVVREDIGLGIAPIGWTNDDMPELGGDIPFEQCIDEMAEAKFEGCEVGNKFPRDPEVLRAALEPRGLQVASAWFSTFFTT
KDPEETYTAFLKHRDFLHAMGAKVIVVSETGKSIQGEINTPLHSAKPIFSDMDWKKLVDGLHELGKLAAEKGMKIVFHHH
MGTGVQTYEEIRKLMELTDPELVYLLVDTGHMVFAGGDPVELIKEFGPRIKHVHFKDLRKDVMERSFKDDLSFLNSVKLG
VFTVPGDGTIDFVPIVKALDEIDYKGWIIVEAEQDPKLAPPLEYAIKARNYLSSVLGF

Specific function: Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D- (3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) [H]

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iolE/mocC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =4.2.1.44 [H]

Molecular weight: Translated: 33392; Mature: 33392

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVREDIGLGIAPIGWTNDDMPELGGDIPFEQCIDEMAEAKFEGCEVGNKFPRDPEVLRA
CCCCCCCCCCEECCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
ALEPRGLQVASAWFSTFFTTKDPEETYTAFLKHRDFLHAMGAKVIVVSETGKSIQGEINT
HHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCC
PLHSAKPIFSDMDWKKLVDGLHELGKLAAEKGMKIVFHHHMGTGVQTYEEIRKLMELTDP
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCC
ELVYLLVDTGHMVFAGGDPVELIKEFGPRIKHVHFKDLRKDVMERSFKDDLSFLNSVKLG
CEEEEEEECCCEEEECCCHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCEE
VFTVPGDGTIDFVPIVKALDEIDYKGWIIVEAEQDPKLAPPLEYAIKARNYLSSVLGF
EEECCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVVREDIGLGIAPIGWTNDDMPELGGDIPFEQCIDEMAEAKFEGCEVGNKFPRDPEVLRA
CCCCCCCCCCEECCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
ALEPRGLQVASAWFSTFFTTKDPEETYTAFLKHRDFLHAMGAKVIVVSETGKSIQGEINT
HHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCC
PLHSAKPIFSDMDWKKLVDGLHELGKLAAEKGMKIVFHHHMGTGVQTYEEIRKLMELTDP
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCC
ELVYLLVDTGHMVFAGGDPVELIKEFGPRIKHVHFKDLRKDVMERSFKDDLSFLNSVKLG
CEEEEEEECCCEEEECCCHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCEE
VFTVPGDGTIDFVPIVKALDEIDYKGWIIVEAEQDPKLAPPLEYAIKARNYLSSVLGF
EEECCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]