Click here to switch to the map view.

The map label for this gene is trpS [H]

Identifier: 239617256

GI number: 239617256

Start: 910015

End: 910998

Strand: Direct

Name: trpS [H]

Synonym: Kole_0864

Alternate gene names: 239617256

Gene position: 910015-910998 (Clockwise)

Preceding gene: 239617253

Following gene: 239617257

Centisome position: 39.53

GC content: 43.5

Gene sequence:

>984_bases
ATGCGTGTCCTTAGTGGAATGCGTTCGACAGGAAAATTACATCTTGGAAATCTTACAGCCCTCGAAAGATGGGTCGAACT
GCAGAATGAAGGAAATGAATGCTACTTTTTTGTCGCTGATTGGCATGCATTAACTTCTCATATAGATTCTACGAATAATT
TTGCCGGTTGGAGTCTGGACATTGTGAAGATATATGTCGCCGCTGGCCTTGATCCGGAAAAATCTGTAATTTTTATTCAA
TCTGCTGTGAAGGAACATGCGGAACTATTCCTTCTTTTCTCCATGCTGGTTTCCGTTTCAAGGCTTGAAAGGATACCAAC
TTACAAAGAACAGAAACAGCAAATAAATGATAGAGATCTTTCCAGCGCTGGCTTTTTGTTGTATCCGGTGTTACAAGCTG
CAGATATATTGATGTACCGTGCCCATGGCGTTCCCGTTGGCGAAGACCAGGTTTACCATATAGAGCTTACCCGTGAAATA
GCACGAAGATTCAACAACCTTTTCGGTGAGGTGTTCCCTGAACCTGAACCGATACTGGCAAAAGTCGCAAAACTTCCGGG
AACCGACGGAAGGAAAATGTCGAAAAGCTACAACAATTTTATACCAATCGATACAGATGAAAAACAGCTCTGGAAAATGA
TAGCTCCTATGATGACCGATCCGGCAAGAAAGAGAAGGACGGACCCGGGTGATCCTGAAAAGTGCCCTGTTTGGGAATAT
CACAAAGCTTTTACCCACTCGCAGGAGGAGTTAGACTGGGTTGTTAATGGCTGTAAAACGGCCGGAATAGGTTGTATAGA
TTGTAAGAAGCTTCTGCACAAGAATCTCAGTGCAAAGCTCAGCCCGATCTGGGAAAAACTGAGAGAGTTCGATAAAAATC
CTGAAGAGGTGAAGAAGATAATTAAAGAAGGAAATGCTAAAGCTCGGGCGTTCGCACAGGAAACGATGAGACTCGTTTAC
GATGCTATGAAATTCGGGTGGTAA

Upstream 100 bases:

>100_bases
CTGACTGCTGGTTGTAGCGATGTTGTTGGAAATGGCGTATGTGTTAAAATATCATGGAAAGCAGCTTAACAGTGGAATTT
ACTATTTTGGAGGTGTCTAA

Downstream 100 bases:

>100_bases
TAGTGGAACAGATGAAACTTATATTCACGCTTCCAGAGTTTGAAGGTCCGCTTGACCTTCTACTCTTTCTTGTTAGAAAA
CATCGCGTGGATATAAGGTC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MRVLSGMRSTGKLHLGNLTALERWVELQNEGNECYFFVADWHALTSHIDSTNNFAGWSLDIVKIYVAAGLDPEKSVIFIQ
SAVKEHAELFLLFSMLVSVSRLERIPTYKEQKQQINDRDLSSAGFLLYPVLQAADILMYRAHGVPVGEDQVYHIELTREI
ARRFNNLFGEVFPEPEPILAKVAKLPGTDGRKMSKSYNNFIPIDTDEKQLWKMIAPMMTDPARKRRTDPGDPEKCPVWEY
HKAFTHSQEELDWVVNGCKTAGIGCIDCKKLLHKNLSAKLSPIWEKLREFDKNPEEVKKIIKEGNAKARAFAQETMRLVY
DAMKFGW

Sequences:

>Translated_327_residues
MRVLSGMRSTGKLHLGNLTALERWVELQNEGNECYFFVADWHALTSHIDSTNNFAGWSLDIVKIYVAAGLDPEKSVIFIQ
SAVKEHAELFLLFSMLVSVSRLERIPTYKEQKQQINDRDLSSAGFLLYPVLQAADILMYRAHGVPVGEDQVYHIELTREI
ARRFNNLFGEVFPEPEPILAKVAKLPGTDGRKMSKSYNNFIPIDTDEKQLWKMIAPMMTDPARKRRTDPGDPEKCPVWEY
HKAFTHSQEELDWVVNGCKTAGIGCIDCKKLLHKNLSAKLSPIWEKLREFDKNPEEVKKIIKEGNAKARAFAQETMRLVY
DAMKFGW
>Mature_327_residues
MRVLSGMRSTGKLHLGNLTALERWVELQNEGNECYFFVADWHALTSHIDSTNNFAGWSLDIVKIYVAAGLDPEKSVIFIQ
SAVKEHAELFLLFSMLVSVSRLERIPTYKEQKQQINDRDLSSAGFLLYPVLQAADILMYRAHGVPVGEDQVYHIELTREI
ARRFNNLFGEVFPEPEPILAKVAKLPGTDGRKMSKSYNNFIPIDTDEKQLWKMIAPMMTDPARKRRTDPGDPEKCPVWEY
HKAFTHSQEELDWVVNGCKTAGIGCIDCKKLLHKNLSAKLSPIWEKLREFDKNPEEVKKIIKEGNAKARAFAQETMRLVY
DAMKFGW

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=331, Percent_Identity=35.0453172205438, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI41352700, Length=181, Percent_Identity=44.1988950276243, Blast_Score=149, Evalue=4e-36,
Organism=Escherichia coli, GI1789786, Length=342, Percent_Identity=34.2105263157895, Blast_Score=166, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71982800, Length=336, Percent_Identity=29.7619047619048, Blast_Score=130, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI71982793, Length=336, Percent_Identity=29.7619047619048, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320474, Length=244, Percent_Identity=38.1147540983607, Blast_Score=139, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24666151, Length=339, Percent_Identity=31.5634218289086, Blast_Score=147, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37463; Mature: 37463

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLSGMRSTGKLHLGNLTALERWVELQNEGNECYFFVADWHALTSHIDSTNNFAGWSLD
CCCHHCCCCCCCEEECCHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHCCCCCCCCCHHH
IVKIYVAAGLDPEKSVIFIQSAVKEHAELFLLFSMLVSVSRLERIPTYKEQKQQINDRDL
HHHHHHHCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCC
SSAGFLLYPVLQAADILMYRAHGVPVGEDQVYHIELTREIARRFNNLFGEVFPEPEPILA
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCHHHH
KVAKLPGTDGRKMSKSYNNFIPIDTDEKQLWKMIAPMMTDPARKRRTDPGDPEKCPVWEY
HHHHCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCHHH
HKAFTHSQEELDWVVNGCKTAGIGCIDCKKLLHKNLSAKLSPIWEKLREFDKNPEEVKKI
HHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHH
IKEGNAKARAFAQETMRLVYDAMKFGW
HHCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVLSGMRSTGKLHLGNLTALERWVELQNEGNECYFFVADWHALTSHIDSTNNFAGWSLD
CCCHHCCCCCCCEEECCHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHCCCCCCCCCHHH
IVKIYVAAGLDPEKSVIFIQSAVKEHAELFLLFSMLVSVSRLERIPTYKEQKQQINDRDL
HHHHHHHCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCC
SSAGFLLYPVLQAADILMYRAHGVPVGEDQVYHIELTREIARRFNNLFGEVFPEPEPILA
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCHHHH
KVAKLPGTDGRKMSKSYNNFIPIDTDEKQLWKMIAPMMTDPARKRRTDPGDPEKCPVWEY
HHHHCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCHHH
HKAFTHSQEELDWVVNGCKTAGIGCIDCKKLLHKNLSAKLSPIWEKLREFDKNPEEVKKI
HHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHH
IKEGNAKARAFAQETMRLVYDAMKFGW
HHCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]