Click here to switch to the map view.

The map label for this gene is mpg1 [H]

Identifier: 239616865

GI number: 239616865

Start: 488211

End: 489335

Strand: Direct

Name: mpg1 [H]

Synonym: Kole_0460

Alternate gene names: 239616865

Gene position: 488211-489335 (Clockwise)

Preceding gene: 239616864

Following gene: 239616871

Centisome position: 21.21

GC content: 42.76

Gene sequence:

>1125_bases
GTGAAAGCAATGATTCTCGCCGCCGGAAAAGGAACAAGGGTAAGACCTTTAACAAACAAAATTCCAAAGCCCATGATACC
AATCGTAACCAAACCTACAATCGAGTTTCTAATCGAGCTTCTAAAAAACCACGATGTTACAGAGATAATGATAAACATCT
CACATCTTGGCTGGCTCATTCAGGACTACCTTAGAAACGGCTCAAAATACGGGGTAAACATTGGCTACTCCTTCGAGGGA
AAGCTTTTGCCAGATGGAACCCTTGAAACTGAACCTATTGGTTCTGCCGGTGGGATGAAACTTATCCAGGAACGCTATAA
CTTTTTTGACGAGACTTTTATCGTACTATGCGGCGACGCAATTGTTGATTTGGACATCACCGAGGCCTATAATTTCCATA
AATCAAAAGGAGCATTAGCTACGATCATAACAAAAGAAGTCAGCAAGGACCAGGTGTCAAATTACGGTATCGTGGTTACA
GATGAAAAAGGGAAAGTGTTGAGTTTTCAGGAAAAACCCTCCCCGGAAGAAGCAAAATCGAACATAGCCAATACCGGCAT
TTACATTTTCGAGCCTGAAATATTTGAACACATACCTTCAGGTGAATTCTACGATATCGGGAGCCAGCTCTTCCCGAAGC
TCGTCAGCGAGGGCAAACCCATTTACGCCTATTCTATGGATTTCAATTGGTTCGACATAGGCCGGAACAAAGATTATCTG
GTTATCCTTGAAAAAGCTCTCTCTGGAGAGATTAAAAACTTCTATCCTGGTGGGAAGGAGATTTATCCGGGTGTCTGGGT
TGGTACAGGGGCGGTAATATCTCAAGGGGTTGAAATAAAACCGCCTGTCTATATAGGAAGCAGTACAATATTGGAGAAAG
GCGTTACTATCACTGGGCCCGCAATCATAGGAGCAAACTGTTATATTAGTAAAGACAGCCACATTGCCAACGCTTTTGTG
ATGGACTATTGTTATTTGAAACCCGGTACCTCTCTTTCCAGAATACTGGTTACTCCAGAATATTTTGTCCATTCTGATGG
CGAAAGTGGAGAAATCTCCGAAAGCCATCTCAGTAAATCCGTAAAGGACGTCCGTACGCTCGGAATAGAAATGAAAGAAG
CATAA

Upstream 100 bases:

>100_bases
ACCATCGGTGGTGCATTGGTTGTCTGTGGGTTCGTGATGTCCATATTCTATTTGCTGATCCGTCTGCGTGAAGAAAAATG
ACCATCAGGAGGGATAAAAA

Downstream 100 bases:

>100_bases
GAAAACTATTTTACGATACAACAAATAAAAGAGGTGGAGCGAACGCTCCACCTTTGTCTTTGCTATTTTCCAAGATCTAT
CAGCACATCATCCATGATAT

Product: Nucleotidyl transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MKAMILAAGKGTRVRPLTNKIPKPMIPIVTKPTIEFLIELLKNHDVTEIMINISHLGWLIQDYLRNGSKYGVNIGYSFEG
KLLPDGTLETEPIGSAGGMKLIQERYNFFDETFIVLCGDAIVDLDITEAYNFHKSKGALATIITKEVSKDQVSNYGIVVT
DEKGKVLSFQEKPSPEEAKSNIANTGIYIFEPEIFEHIPSGEFYDIGSQLFPKLVSEGKPIYAYSMDFNWFDIGRNKDYL
VILEKALSGEIKNFYPGGKEIYPGVWVGTGAVISQGVEIKPPVYIGSSTILEKGVTITGPAIIGANCYISKDSHIANAFV
MDYCYLKPGTSLSRILVTPEYFVHSDGESGEISESHLSKSVKDVRTLGIEMKEA

Sequences:

>Translated_374_residues
MKAMILAAGKGTRVRPLTNKIPKPMIPIVTKPTIEFLIELLKNHDVTEIMINISHLGWLIQDYLRNGSKYGVNIGYSFEG
KLLPDGTLETEPIGSAGGMKLIQERYNFFDETFIVLCGDAIVDLDITEAYNFHKSKGALATIITKEVSKDQVSNYGIVVT
DEKGKVLSFQEKPSPEEAKSNIANTGIYIFEPEIFEHIPSGEFYDIGSQLFPKLVSEGKPIYAYSMDFNWFDIGRNKDYL
VILEKALSGEIKNFYPGGKEIYPGVWVGTGAVISQGVEIKPPVYIGSSTILEKGVTITGPAIIGANCYISKDSHIANAFV
MDYCYLKPGTSLSRILVTPEYFVHSDGESGEISESHLSKSVKDVRTLGIEMKEA
>Mature_374_residues
MKAMILAAGKGTRVRPLTNKIPKPMIPIVTKPTIEFLIELLKNHDVTEIMINISHLGWLIQDYLRNGSKYGVNIGYSFEG
KLLPDGTLETEPIGSAGGMKLIQERYNFFDETFIVLCGDAIVDLDITEAYNFHKSKGALATIITKEVSKDQVSNYGIVVT
DEKGKVLSFQEKPSPEEAKSNIANTGIYIFEPEIFEHIPSGEFYDIGSQLFPKLVSEGKPIYAYSMDFNWFDIGRNKDYL
VILEKALSGEIKNFYPGGKEIYPGVWVGTGAVISQGVEIKPPVYIGSSTILEKGVTITGPAIIGANCYISKDSHIANAFV
MDYCYLKPGTSLSRILVTPEYFVHSDGESGEISESHLSKSVKDVRTLGIEMKEA

Specific function: Glycogen biosynthesis; first step. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=329, Percent_Identity=28.8753799392097, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI11761619, Length=329, Percent_Identity=28.8753799392097, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI31881779, Length=335, Percent_Identity=24.7761194029851, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI45447090, Length=335, Percent_Identity=24.7761194029851, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1789837, Length=243, Percent_Identity=27.1604938271605, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788351, Length=196, Percent_Identity=29.0816326530612, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790224, Length=199, Percent_Identity=27.1356783919598, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI133931050, Length=361, Percent_Identity=30.4709141274238, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17509979, Length=317, Percent_Identity=27.7602523659306, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17509981, Length=307, Percent_Identity=27.0358306188925, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6320148, Length=342, Percent_Identity=32.1637426900585, Blast_Score=146, Evalue=5e-36,
Organism=Drosophila melanogaster, GI21355443, Length=306, Percent_Identity=32.0261437908497, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24644084, Length=306, Percent_Identity=32.0261437908497, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24653912, Length=212, Percent_Identity=32.5471698113208, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 41303; Mature: 41303

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAMILAAGKGTRVRPLTNKIPKPMIPIVTKPTIEFLIELLKNHDVTEIMINISHLGWLI
CCEEEEECCCCCEECCHHHCCCCCCCCEECCHHHHHHHHHHHCCCHHHEEEEHHHHHHHH
QDYLRNGSKYGVNIGYSFEGKLLPDGTLETEPIGSAGGMKLIQERYNFFDETFIVLCGDA
HHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCE
IVDLDITEAYNFHKSKGALATIITKEVSKDQVSNYGIVVTDEKGKVLSFQEKPSPEEAKS
EEEEEHHHHHCCCCCCCCEEEEEEHHHCHHHHCCCCEEEECCCCCEEEECCCCCHHHHHH
NIANTGIYIFEPEIFEHIPSGEFYDIGSQLFPKLVSEGKPIYAYSMDFNWFDIGRNKDYL
HHHHCCEEEECCHHHHHCCCCCEECCHHHHHHHHHHCCCCEEEEEECCCEEECCCCCCEE
VILEKALSGEIKNFYPGGKEIYPGVWVGTGAVISQGVEIKPPVYIGSSTILEKGVTITGP
EEEEEHHCCCHHHCCCCCCEECCCEEECCCHHHHCCCEECCCEEECCHHHHHCCCEEECC
AIIGANCYISKDSHIANAFVMDYCYLKPGTSLSRILVTPEYFVHSDGESGEISESHLSKS
EEECCEEEEECCCCHHHHEEEHEEEECCCCCCEEEEECCCCEEECCCCCCCCCHHHHHHH
VKDVRTLGIEMKEA
HHHHHHHCCEECCC
>Mature Secondary Structure
MKAMILAAGKGTRVRPLTNKIPKPMIPIVTKPTIEFLIELLKNHDVTEIMINISHLGWLI
CCEEEEECCCCCEECCHHHCCCCCCCCEECCHHHHHHHHHHHCCCHHHEEEEHHHHHHHH
QDYLRNGSKYGVNIGYSFEGKLLPDGTLETEPIGSAGGMKLIQERYNFFDETFIVLCGDA
HHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCE
IVDLDITEAYNFHKSKGALATIITKEVSKDQVSNYGIVVTDEKGKVLSFQEKPSPEEAKS
EEEEEHHHHHCCCCCCCCEEEEEEHHHCHHHHCCCCEEEECCCCCEEEECCCCCHHHHHH
NIANTGIYIFEPEIFEHIPSGEFYDIGSQLFPKLVSEGKPIYAYSMDFNWFDIGRNKDYL
HHHHCCEEEECCHHHHHCCCCCEECCHHHHHHHHHHCCCCEEEEEECCCEEECCCCCCEE
VILEKALSGEIKNFYPGGKEIYPGVWVGTGAVISQGVEIKPPVYIGSSTILEKGVTITGP
EEEEEHHCCCHHHCCCCCCEECCCEEECCCHHHHCCCEECCCEEECCHHHHHCCCEEECC
AIIGANCYISKDSHIANAFVMDYCYLKPGTSLSRILVTPEYFVHSDGESGEISESHLSKS
EEECCEEEEECCCCHHHHEEEHEEEECCCCCCEEEEECCCCEEECCCCCCCCCHHHHHHH
VKDVRTLGIEMKEA
HHHHHHHCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]