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The map label for this gene is mtnN [H]

Identifier: 238924950

GI number: 238924950

Start: 2476784

End: 2477479

Strand: Reverse

Name: mtnN [H]

Synonym: EUBREC_2601

Alternate gene names: 238924950

Gene position: 2477479-2476784 (Counterclockwise)

Preceding gene: 238924951

Following gene: 238924949

Centisome position: 71.82

GC content: 45.55

Gene sequence:

>696_bases
ATGACAATAGGTGTAATTGGTGCAATGCAGATGGAGGTCGATGACCTAAAGGCTCAGATGACAGACACACAGACAGAGGT
TTACAGCGGTGTGGAGTTTGTTGAGGGTAAAATCGGTGATCAGTATGTAGTTGCGGCAAAATGCGGAATAGGAAAGGTAT
TTGCGGCAATATGTGCAGAGACCATGATTTTGAAATATGATGTAGATATGATTGTCAATATCGGAGTGGCTGGTACTTTG
ACAAAGGACTTAAATGTGCTTGACGTGGCAGTAGCCACAAACGTGCTGCAGCACGATATGGATACATCGCCAATCGGAGA
TCCGAAGGGACTTCTTTCAGGCATCAATATGATTCTGCTTCCGGCAGATACAAAAATGGTGGAGCTCATGTGCTCATGCT
TAGCTGACAGGAATATCCACTACAAAAAGGGCAATATCGCAACAGGAGATCAGTTTATTGCCACAAAGGAGCAGAAGGAT
TATATTTCGAATACCTTTGATGCAATCGCAGCAGAGATGGAGGGAGGCAGCATCGGTCATGTGTGCTATGTGAACAATGT
GCCATTTGCTATTCTTCGTTCAATATCAGACGGCGATGGCGGCGAGACAGACTACCAGACCTTTGCGGAGAAGGCTGCGC
ATCAGTCGATTGAGGTAGTGCTTGAGTTTATCGGAAGGGCAGAAGAACTGAAATAG

Upstream 100 bases:

>100_bases
TCTTAAGGTGCTTGAGAGTCAGACAAATATGGAGTTTACTTATCCACAGTAAACGAGGACTAAAAATATAATAGCAAGAT
AGCAGGAATGGAGAAATAAA

Downstream 100 bases:

>100_bases
AGTTATTTCATTATTCATAATTTGTGATAATAAAGAATAGTATATAGCATGAGTGAATACAGAGCATACATGCAAAATAC
AAAACTACATAATGGGACAA

Product: 5-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MTIGVIGAMQMEVDDLKAQMTDTQTEVYSGVEFVEGKIGDQYVVAAKCGIGKVFAAICAETMILKYDVDMIVNIGVAGTL
TKDLNVLDVAVATNVLQHDMDTSPIGDPKGLLSGINMILLPADTKMVELMCSCLADRNIHYKKGNIATGDQFIATKEQKD
YISNTFDAIAAEMEGGSIGHVCYVNNVPFAILRSISDGDGGETDYQTFAEKAAHQSIEVVLEFIGRAEELK

Sequences:

>Translated_231_residues
MTIGVIGAMQMEVDDLKAQMTDTQTEVYSGVEFVEGKIGDQYVVAAKCGIGKVFAAICAETMILKYDVDMIVNIGVAGTL
TKDLNVLDVAVATNVLQHDMDTSPIGDPKGLLSGINMILLPADTKMVELMCSCLADRNIHYKKGNIATGDQFIATKEQKD
YISNTFDAIAAEMEGGSIGHVCYVNNVPFAILRSISDGDGGETDYQTFAEKAAHQSIEVVLEFIGRAEELK
>Mature_230_residues
TIGVIGAMQMEVDDLKAQMTDTQTEVYSGVEFVEGKIGDQYVVAAKCGIGKVFAAICAETMILKYDVDMIVNIGVAGTLT
KDLNVLDVAVATNVLQHDMDTSPIGDPKGLLSGINMILLPADTKMVELMCSCLADRNIHYKKGNIATGDQFIATKEQKDY
ISNTFDAIAAEMEGGSIGHVCYVNNVPFAILRSISDGDGGETDYQTFAEKAAHQSIEVVLEFIGRAEELK

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=219, Percent_Identity=36.5296803652968, Blast_Score=100, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 24871; Mature: 24740

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIGVIGAMQMEVDDLKAQMTDTQTEVYSGVEFVEGKIGDQYVVAAKCGIGKVFAAICAE
CEEEEEEEEEEHHHHHHHHHHHHHHHHHHCHHHHCCCCCCEEEEEEECCHHHHHHHHHHH
TMILKYDVDMIVNIGVAGTLTKDLNVLDVAVATNVLQHDMDTSPIGDPKGLLSGINMILL
HHHEEECHHEEEECCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCEEEE
PADTKMVELMCSCLADRNIHYKKGNIATGDQFIATKEQKDYISNTFDAIAAEMEGGSIGH
ECCHHHHHHHHHHHHCCCCEEECCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCEEE
VCYVNNVPFAILRSISDGDGGETDYQTFAEKAAHQSIEVVLEFIGRAEELK
EEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TIGVIGAMQMEVDDLKAQMTDTQTEVYSGVEFVEGKIGDQYVVAAKCGIGKVFAAICAE
EEEEEEEEEEHHHHHHHHHHHHHHHHHHCHHHHCCCCCCEEEEEEECCHHHHHHHHHHH
TMILKYDVDMIVNIGVAGTLTKDLNVLDVAVATNVLQHDMDTSPIGDPKGLLSGINMILL
HHHEEECHHEEEECCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCEEEE
PADTKMVELMCSCLADRNIHYKKGNIATGDQFIATKEQKDYISNTFDAIAAEMEGGSIGH
ECCHHHHHHHHHHHHCCCCEEECCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCEEE
VCYVNNVPFAILRSISDGDGGETDYQTFAEKAAHQSIEVVLEFIGRAEELK
EEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA