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The map label for this gene is luxS [H]

Identifier: 238924951

GI number: 238924951

Start: 2477528

End: 2477986

Strand: Reverse

Name: luxS [H]

Synonym: EUBREC_2602

Alternate gene names: 238924951

Gene position: 2477986-2477528 (Counterclockwise)

Preceding gene: 238924952

Following gene: 238924950

Centisome position: 71.83

GC content: 40.52

Gene sequence:

>459_bases
ATGGAAAGAATTAAAAGCTTTACAATCAATCATAATATTCTTAAACCTGGATTTTATATTTCAAGAAAAGACGGAGAAAT
CGTTACATACGACCTTCGTACAAGAAAACCTAATGCAGGAGATTATATGTCCAATTCAGCTATGCACTCAGTGGAGCATA
TGTTTGCGACATGTGTGAGAAACTCTGAGATTGCAGATGATGTGGTATATTTTGGACCGATGGGATGTCAGACAGGCTTC
TATCTCGTAGTGAGGGATGTCGAGCCGGGAAAGGTTTTTGAAATCACCAAAGAGGTCTTAAAGCAGATACTTGAGTATGA
TGGACCGGTGTTTGGTGCATCAGCCATAGAGTGCGGACATTACGAGAATCTGTCACTTGACGAGGCAAAGAAGGAGTGTC
GTGCATATCTTAAGGTGCTTGAGAGTCAGACAAATATGGAGTTTACTTATCCACAGTAA

Upstream 100 bases:

>100_bases
TCGATATGAGCACACCAAAGCCTGTGGATGATGCACTCAATGTATTTGAGGATTATCTGAAGCAGTTTGAGACAGCAACT
AAGTAAGGAGAAACATTTTT

Downstream 100 bases:

>100_bases
ACGAGGACTAAAAATATAATAGCAAGATAGCAGGAATGGAGAAATAAAATGACAATAGGTGTAATTGGTGCAATGCAGAT
GGAGGTCGATGACCTAAAGG

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS [H]

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MERIKSFTINHNILKPGFYISRKDGEIVTYDLRTRKPNAGDYMSNSAMHSVEHMFATCVRNSEIADDVVYFGPMGCQTGF
YLVVRDVEPGKVFEITKEVLKQILEYDGPVFGASAIECGHYENLSLDEAKKECRAYLKVLESQTNMEFTYPQ

Sequences:

>Translated_152_residues
MERIKSFTINHNILKPGFYISRKDGEIVTYDLRTRKPNAGDYMSNSAMHSVEHMFATCVRNSEIADDVVYFGPMGCQTGF
YLVVRDVEPGKVFEITKEVLKQILEYDGPVFGASAIECGHYENLSLDEAKKECRAYLKVLESQTNMEFTYPQ
>Mature_152_residues
MERIKSFTINHNILKPGFYISRKDGEIVTYDLRTRKPNAGDYMSNSAMHSVEHMFATCVRNSEIADDVVYFGPMGCQTGF
YLVVRDVEPGKVFEITKEVLKQILEYDGPVFGASAIECGHYENLSLDEAKKECRAYLKVLESQTNMEFTYPQ

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family [H]

Homologues:

Organism=Escherichia coli, GI1789043, Length=164, Percent_Identity=26.8292682926829, Blast_Score=61, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR003815
- ProDom:   PD013172 [H]

Pfam domain/function: PF02664 LuxS [H]

EC number: =4.4.1.21 [H]

Molecular weight: Translated: 17368; Mature: 17368

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERIKSFTINHNILKPGFYISRKDGEIVTYDLRTRKPNAGDYMSNSAMHSVEHMFATCVR
CCCCCEEECCCCEECCCEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHC
NSEIADDVVYFGPMGCQTGFYLVVRDVEPGKVFEITKEVLKQILEYDGPVFGASAIECGH
CCCCCCCEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCEECCC
YENLSLDEAKKECRAYLKVLESQTNMEFTYPQ
CCCCCHHHHHHHHHHHHHHHHHCCCCEEECCC
>Mature Secondary Structure
MERIKSFTINHNILKPGFYISRKDGEIVTYDLRTRKPNAGDYMSNSAMHSVEHMFATCVR
CCCCCEEECCCCEECCCEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHC
NSEIADDVVYFGPMGCQTGFYLVVRDVEPGKVFEITKEVLKQILEYDGPVFGASAIECGH
CCCCCCCEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCEECCC
YENLSLDEAKKECRAYLKVLESQTNMEFTYPQ
CCCCCHHHHHHHHHHHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA