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The map label for this gene is yycF [H]

Identifier: 238923975

GI number: 238923975

Start: 1501406

End: 1502098

Strand: Direct

Name: yycF [H]

Synonym: EUBREC_1613

Alternate gene names: 238923975

Gene position: 1501406-1502098 (Clockwise)

Preceding gene: 238923974

Following gene: 238923976

Centisome position: 43.52

GC content: 43.43

Gene sequence:

>693_bases
ATGGCAAAAAAAGTGCTGGTCGTTGACGACGAAAAGTTAATTGTAAAAGGAATACGTTTCAGTCTGCTGCAGGATGGCAT
GGAAGTAGACTGCGCATATGACGGTGAGGAGGCCTTAAATATGGCGAAGGCCAATTCATATGATATGATTCTTTTAGATG
TCATGCTTCCAAAGATGGATGGTTTTGAGGTGTGTCAGGCAATAAGGGAGTTTTCTGATGTCCCGATTGTCATGCTCACT
GCAAAGGGCGATGACATGGACAAAATTTTAGGACTTGAGTACGGCGCTGATGACTATATCACAAAGCCATTTAATATTCT
TGAGGTAAAGGCCAGAATCAAGGCAATCATGCGGCGTACTTCACCGGAACGTGCACCACAGGTACAGTCATCTGTAATTG
AAAAGGGTGATATCAAGCTCGACTGTGACAGCAGACGTCTGTTCATAAACGATAATGAAATCAATTTGACTGCAAGAGAG
TTTGAACTGCTCGAGATTCTGATAAAAAATGAAAATAAAGTGTACAGTAGGGAGAGCCTTTTAAAGATTGTATGGGGCGA
GGATTACCCGGGTGACGTGCGTACGGTTGATGTGCATGTCAGACGTCTTCGTGAAAAGATTGAGGCAAATCCAAGCGAGC
CGAAGTACGTTCATACCAAGTGGGGTGTGGGATATTACTACAACCAGAAGTAA

Upstream 100 bases:

>100_bases
TTGTTTTCTTCGATTGAGGATATCACGAGGGTGTCCGGCATCGGTGAAACGATGTTTAATAAAATAAAAGATGATATAAC
AGTAAATTAGGAGTGTATAA

Downstream 100 bases:

>100_bases
TACTTTCAGAAAGGTTCTAAAATGTTTAAGAGTAAAGTACATTTTGCATTTTATAAGAGTCTGAAATCCAGGCTGATTTT
CATGATTTTTGTTCTCGTTC

Product: response regulators consisting of a CheY-like receiver domain and a HTH DNA-binding domain

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MAKKVLVVDDEKLIVKGIRFSLLQDGMEVDCAYDGEEALNMAKANSYDMILLDVMLPKMDGFEVCQAIREFSDVPIVMLT
AKGDDMDKILGLEYGADDYITKPFNILEVKARIKAIMRRTSPERAPQVQSSVIEKGDIKLDCDSRRLFINDNEINLTARE
FELLEILIKNENKVYSRESLLKIVWGEDYPGDVRTVDVHVRRLREKIEANPSEPKYVHTKWGVGYYYNQK

Sequences:

>Translated_230_residues
MAKKVLVVDDEKLIVKGIRFSLLQDGMEVDCAYDGEEALNMAKANSYDMILLDVMLPKMDGFEVCQAIREFSDVPIVMLT
AKGDDMDKILGLEYGADDYITKPFNILEVKARIKAIMRRTSPERAPQVQSSVIEKGDIKLDCDSRRLFINDNEINLTARE
FELLEILIKNENKVYSRESLLKIVWGEDYPGDVRTVDVHVRRLREKIEANPSEPKYVHTKWGVGYYYNQK
>Mature_229_residues
AKKVLVVDDEKLIVKGIRFSLLQDGMEVDCAYDGEEALNMAKANSYDMILLDVMLPKMDGFEVCQAIREFSDVPIVMLTA
KGDDMDKILGLEYGADDYITKPFNILEVKARIKAIMRRTSPERAPQVQSSVIEKGDIKLDCDSRRLFINDNEINLTAREF
ELLEILIKNENKVYSRESLLKIVWGEDYPGDVRTVDVHVRRLREKIEANPSEPKYVHTKWGVGYYYNQK

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=38.3259911894273, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=41.2017167381974, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=35.8744394618834, Blast_Score=155, Evalue=1e-39,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=37.280701754386, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=36.322869955157, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=35.7142857142857, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=32.1428571428571, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=32.4561403508772, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=34.6666666666667, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=38.3259911894273, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=32.7510917030568, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=33.0396475770925, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI1790552, Length=205, Percent_Identity=32.1951219512195, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI145693140, Length=237, Percent_Identity=31.6455696202532, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788550, Length=128, Percent_Identity=28.90625, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=32.5, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI145693157, Length=121, Percent_Identity=31.404958677686, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26460; Mature: 26329

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKVLVVDDEKLIVKGIRFSLLQDGMEVDCAYDGEEALNMAKANSYDMILLDVMLPKMD
CCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHCCCCCCEEEEEECCCCCC
GFEVCQAIREFSDVPIVMLTAKGDDMDKILGLEYGADDYITKPFNILEVKARIKAIMRRT
CHHHHHHHHHHCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
SPERAPQVQSSVIEKGDIKLDCDSRRLFINDNEINLTAREFELLEILIKNENKVYSRESL
CCCCCHHHHHHHHHCCCEEEECCCCEEEEECCEEEEEHHHHHHHHHHHCCCCCEECHHHE
LKIVWGEDYPGDVRTVDVHVRRLREKIEANPSEPKYVHTKWGVGYYYNQK
EEEEECCCCCCCEEEHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEECCC
>Mature Secondary Structure 
AKKVLVVDDEKLIVKGIRFSLLQDGMEVDCAYDGEEALNMAKANSYDMILLDVMLPKMD
CCEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHCCCCCCEEEEEECCCCCC
GFEVCQAIREFSDVPIVMLTAKGDDMDKILGLEYGADDYITKPFNILEVKARIKAIMRRT
CHHHHHHHHHHCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
SPERAPQVQSSVIEKGDIKLDCDSRRLFINDNEINLTAREFELLEILIKNENKVYSRESL
CCCCCHHHHHHHHHCCCEEEECCCCEEEEECCEEEEEHHHHHHHHHHHCCCCCEECHHHE
LKIVWGEDYPGDVRTVDVHVRRLREKIEANPSEPKYVHTKWGVGYYYNQK
EEEEECCCCCCCEEEHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]