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The map label for this gene is yycG [H]

Identifier: 238923976

GI number: 238923976

Start: 1502120

End: 1503571

Strand: Direct

Name: yycG [H]

Synonym: EUBREC_1614

Alternate gene names: 238923976

Gene position: 1502120-1503571 (Clockwise)

Preceding gene: 238923975

Following gene: 238923977

Centisome position: 43.54

GC content: 42.91

Gene sequence:

>1452_bases
ATGTTTAAGAGTAAAGTACATTTTGCATTTTATAAGAGTCTGAAATCCAGGCTGATTTTCATGATTTTTGTTCTCGTTCT
GGTACCGGAGGTGGTGCTGTGCTTCGGCATACTTAACACCTACGAGTCCAGAGCGGTTTCAATCCGCGAAAGTGAAGTGC
TTAGTCAGGCAAAGATTCTCGCAAACAAGATATCCACAAGTAAATACTTTGATAAGGATGGCAGTGACTTGAGTAATATT
GATGCTCAGATTGACACTCTTACTACTATATATGAGGGCCGTGTGCTCATAGTTGACAAGCATTTTAAGATTATTAAGGA
TACGTACAATTTAGATGATGGCAATACTATTGTCTCAGAGGAGGTTATCAAGACCTTCTCTGCTTCAGAGATTACTAACT
ATGATTCTAAAAACCACTATATCGAGCTTTCTGTTCCGATAAGCAATCCAAACGACAAGGATTCAAAGATAGAGGGAGCA
CTTGTTGTAAGTGTGTCGACGGACAATATATCGCTAAATATGTCGTATCTGACACAGATTGCTGTGACGGTTGCTATTAT
CGCAGGTGCGGTGGTGCTCTTTTTTGGTGTGCTTGTGCTTTTGCACCTTTTTGTTCCGATTAAGAAGCTTTCTGACGAGA
TATCAGACATTAAGGATGGCTTTGGAAAAGAGCAGCTGGATGTAGATGACTATGCGGAGACTGCTATAATAAGCAGGAAT
TTTAATGAGCTGATGAGCGGAATGAAGGTCATGGATGAGTCCAGACAGGAGTTTGTATCGAATGTGTCACATGAGCTCAA
GACACCTCTTACTTCCATGAAGGTACTCGCAGATTCCATCAACAGCATGGGTGATGAGGCTCCGATTGAGATGTACAGGG
AGTTCATGGGAGATATCACAAGCGAGATAGACAGAGAGACAAAGATAATAAATGACCTGTTATCACTGGTTAAGATGGAT
AAGTCGGCTGCCACGCTGAATATCGAGAGTGTTAATATCAATGACCTGCTCGAGCAGATTATGAAGAGACTTCAGCCGAT
TGCTGACAAGCAGCAGGTGGAGCTTGTACTCGAGAGCTTCAGACCGGTAACTGCAGAGATAGATGAGGTGAAGCTGACGC
TTGCTTTTACAAACCTCATTGAGAATGCAATCAAGTACAATGACAATGAGACCGGTGGCTATGTGCATGTATCCTTAAAT
GCGGATCATCAGTATTTCTATCTGAAGGTGGAGGACAACGGTATCGGTATACCGGAGGAGTCCTTAGAGCACATCTATGA
GAGATTTTATCGCGTGGACAAGTCGCATTCGAGAGAGATTGGCGGTACAGGTCTGGGACTTGCCATTACAAGAAGCTCTA
TTCTTATGCATAGGGGAGCTATAAAGGCTCACAGTGTGATGGGAGAGGGCACTACCTTTGATGTGCGTATACCGCTCAAC
TATATTGTATAG

Upstream 100 bases:

>100_bases
AAAGATTGAGGCAAATCCAAGCGAGCCGAAGTACGTTCATACCAAGTGGGGTGTGGGATATTACTACAACCAGAAGTAAT
ACTTTCAGAAAGGTTCTAAA

Downstream 100 bases:

>100_bases
GAGGCTTGACGTGAAAAGAATAATTATATTCGTGCTCACTGCAGTAATTCTGCTCTCCATGGGCGGCTGCACAAAGAAAA
AAGCAGATAATACGGTTGAG

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MFKSKVHFAFYKSLKSRLIFMIFVLVLVPEVVLCFGILNTYESRAVSIRESEVLSQAKILANKISTSKYFDKDGSDLSNI
DAQIDTLTTIYEGRVLIVDKHFKIIKDTYNLDDGNTIVSEEVIKTFSASEITNYDSKNHYIELSVPISNPNDKDSKIEGA
LVVSVSTDNISLNMSYLTQIAVTVAIIAGAVVLFFGVLVLLHLFVPIKKLSDEISDIKDGFGKEQLDVDDYAETAIISRN
FNELMSGMKVMDESRQEFVSNVSHELKTPLTSMKVLADSINSMGDEAPIEMYREFMGDITSEIDRETKIINDLLSLVKMD
KSAATLNIESVNINDLLEQIMKRLQPIADKQQVELVLESFRPVTAEIDEVKLTLAFTNLIENAIKYNDNETGGYVHVSLN
ADHQYFYLKVEDNGIGIPEESLEHIYERFYRVDKSHSREIGGTGLGLAITRSSILMHRGAIKAHSVMGEGTTFDVRIPLN
YIV

Sequences:

>Translated_483_residues
MFKSKVHFAFYKSLKSRLIFMIFVLVLVPEVVLCFGILNTYESRAVSIRESEVLSQAKILANKISTSKYFDKDGSDLSNI
DAQIDTLTTIYEGRVLIVDKHFKIIKDTYNLDDGNTIVSEEVIKTFSASEITNYDSKNHYIELSVPISNPNDKDSKIEGA
LVVSVSTDNISLNMSYLTQIAVTVAIIAGAVVLFFGVLVLLHLFVPIKKLSDEISDIKDGFGKEQLDVDDYAETAIISRN
FNELMSGMKVMDESRQEFVSNVSHELKTPLTSMKVLADSINSMGDEAPIEMYREFMGDITSEIDRETKIINDLLSLVKMD
KSAATLNIESVNINDLLEQIMKRLQPIADKQQVELVLESFRPVTAEIDEVKLTLAFTNLIENAIKYNDNETGGYVHVSLN
ADHQYFYLKVEDNGIGIPEESLEHIYERFYRVDKSHSREIGGTGLGLAITRSSILMHRGAIKAHSVMGEGTTFDVRIPLN
YIV
>Mature_483_residues
MFKSKVHFAFYKSLKSRLIFMIFVLVLVPEVVLCFGILNTYESRAVSIRESEVLSQAKILANKISTSKYFDKDGSDLSNI
DAQIDTLTTIYEGRVLIVDKHFKIIKDTYNLDDGNTIVSEEVIKTFSASEITNYDSKNHYIELSVPISNPNDKDSKIEGA
LVVSVSTDNISLNMSYLTQIAVTVAIIAGAVVLFFGVLVLLHLFVPIKKLSDEISDIKDGFGKEQLDVDDYAETAIISRN
FNELMSGMKVMDESRQEFVSNVSHELKTPLTSMKVLADSINSMGDEAPIEMYREFMGDITSEIDRETKIINDLLSLVKMD
KSAATLNIESVNINDLLEQIMKRLQPIADKQQVELVLESFRPVTAEIDEVKLTLAFTNLIENAIKYNDNETGGYVHVSLN
ADHQYFYLKVEDNGIGIPEESLEHIYERFYRVDKSHSREIGGTGLGLAITRSSILMHRGAIKAHSVMGEGTTFDVRIPLN
YIV

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=241, Percent_Identity=31.9502074688797, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788393, Length=278, Percent_Identity=28.0575539568345, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1790346, Length=277, Percent_Identity=27.4368231046931, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI145693157, Length=252, Percent_Identity=28.1746031746032, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1786783, Length=311, Percent_Identity=25.4019292604502, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1787894, Length=317, Percent_Identity=25.2365930599369, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI48994928, Length=230, Percent_Identity=29.5652173913043, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789808, Length=278, Percent_Identity=24.4604316546763, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789149, Length=236, Percent_Identity=31.3559322033898, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789403, Length=293, Percent_Identity=25.938566552901, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788279, Length=300, Percent_Identity=22, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786912, Length=234, Percent_Identity=26.0683760683761, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790436, Length=227, Percent_Identity=26.431718061674, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1790861, Length=355, Percent_Identity=21.9718309859155, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788549, Length=227, Percent_Identity=26.8722466960352, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787374, Length=424, Percent_Identity=22.1698113207547, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87081816, Length=231, Percent_Identity=25.1082251082251, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87082128, Length=304, Percent_Identity=25.9868421052632, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790551, Length=292, Percent_Identity=24.6575342465753, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788713, Length=233, Percent_Identity=24.0343347639485, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322044, Length=100, Percent_Identity=36, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54206; Mature: 54206

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKSKVHFAFYKSLKSRLIFMIFVLVLVPEVVLCFGILNTYESRAVSIRESEVLSQAKIL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHH
ANKISTSKYFDKDGSDLSNIDAQIDTLTTIYEGRVLIVDKHFKIIKDTYNLDDGNTIVSE
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHCCCCCCCCEEHHH
EVIKTFSASEITNYDSKNHYIELSVPISNPNDKDSKIEGALVVSVSTDNISLNMSYLTQI
HHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCEEEEHHHHHHH
AVTVAIIAGAVVLFFGVLVLLHLFVPIKKLSDEISDIKDGFGKEQLDVDDYAETAIISRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC
FNELMSGMKVMDESRQEFVSNVSHELKTPLTSMKVLADSINSMGDEAPIEMYREFMGDIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
SEIDRETKIINDLLSLVKMDKSAATLNIESVNINDLLEQIMKRLQPIADKQQVELVLESF
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHC
RPVTAEIDEVKLTLAFTNLIENAIKYNDNETGGYVHVSLNADHQYFYLKVEDNGIGIPEE
CCCCCCHHHEEEHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEEEEECCCCCCCHH
SLEHIYERFYRVDKSHSREIGGTGLGLAITRSSILMHRGAIKAHSVMGEGTTFDVRIPLN
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCCCEEEEEECHH
YIV
CCC
>Mature Secondary Structure
MFKSKVHFAFYKSLKSRLIFMIFVLVLVPEVVLCFGILNTYESRAVSIRESEVLSQAKIL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHH
ANKISTSKYFDKDGSDLSNIDAQIDTLTTIYEGRVLIVDKHFKIIKDTYNLDDGNTIVSE
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHCCCCCCCCEEHHH
EVIKTFSASEITNYDSKNHYIELSVPISNPNDKDSKIEGALVVSVSTDNISLNMSYLTQI
HHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCEEEEHHHHHHH
AVTVAIIAGAVVLFFGVLVLLHLFVPIKKLSDEISDIKDGFGKEQLDVDDYAETAIISRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC
FNELMSGMKVMDESRQEFVSNVSHELKTPLTSMKVLADSINSMGDEAPIEMYREFMGDIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
SEIDRETKIINDLLSLVKMDKSAATLNIESVNINDLLEQIMKRLQPIADKQQVELVLESF
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHC
RPVTAEIDEVKLTLAFTNLIENAIKYNDNETGGYVHVSLNADHQYFYLKVEDNGIGIPEE
CCCCCCHHHEEEHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEEEEECCCCCCCHH
SLEHIYERFYRVDKSHSREIGGTGLGLAITRSSILMHRGAIKAHSVMGEGTTFDVRIPLN
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCCCEEEEEECHH
YIV
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]