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The map label for this gene is rnhB [H]

Identifier: 238923885

GI number: 238923885

Start: 1392820

End: 1393581

Strand: Direct

Name: rnhB [H]

Synonym: EUBREC_1513

Alternate gene names: 238923885

Gene position: 1392820-1393581 (Clockwise)

Preceding gene: 238923884

Following gene: 238923886

Centisome position: 40.38

GC content: 45.41

Gene sequence:

>762_bases
ATGTCAGCAGAAAAAATAGGCGATATTAAGGAACAACTGAAAAGTATCACAGATTCACAGCTTGCACAGTTCATTGAGGC
ATACGGCTCAGATGAAAGGGGCGGAGTGATTAAGCTTGTAGACAGTGCAAAAAAGCGTCTGGACAAGTATGAGAAGGAGC
TTATCCGCACAGAAGGTCTCAAGAAATATGAGCGTGAGTACGCATCATATGCTCATATTTGCGGCATAGATGAGGTGGGA
CGCGGACCGCTTGCAGGTCCGGTTGTGGCATGTGCGGTTATTCTGCCAAAGGACTGTGATATTTTATATATCAATGATTC
AAAGAAGCTTACGGCTGCAAAGCGCGATGAGCTTTACGATGTCATAATGGAAAAGGCGGTTTCTGTAGGAATAGGTATGG
CATCGCACGAGCGGATAGATGAGATAAATATATTGCAGGCTACATATGAGGCGATGAGACAGGCAATCGGAAAGCTTGAT
CCGGCACCGGATTTGACACTTAACGATGCAGTCACCATCCCGGGGGTGGATATAAAGCAGGTCCCGATTATAAAGGGAGA
TGCCAAAAGCATATCAATAGGGGCAGCCAGCATTGTGGCTAAGGTCACAAGGGATCGGATGATGGTTGAGTATGATAACA
TATATCCCGGCTATGGATTTGCATCAAACAAGGGCTATGGCTCGGCAGAGCATATCAAGGCACTAAAGAAGATAGGACCA
TCACCGATACACAGGGCATCGTTTATACACAATTTTATCTAA

Upstream 100 bases:

>100_bases
ATCATAGATGATTTCAGAAGTGGTAAATTAGGTCATATCACTTTGGAGAGACCGGAGATATAGAAGAATAGTTACGAAAA
ATAGACGATAGGACAAGGAT

Downstream 100 bases:

>100_bases
TATAATACAATTGTGCGGTTTTTACGAAGGTGCCTGGGCGCTGAATAGTTACACATTCTGCTAAAAACCGTCAGTTCACA
ATAGGAGAGAAAATGACACT

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII [H]

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MSAEKIGDIKEQLKSITDSQLAQFIEAYGSDERGGVIKLVDSAKKRLDKYEKELIRTEGLKKYEREYASYAHICGIDEVG
RGPLAGPVVACAVILPKDCDILYINDSKKLTAAKRDELYDVIMEKAVSVGIGMASHERIDEINILQATYEAMRQAIGKLD
PAPDLTLNDAVTIPGVDIKQVPIIKGDAKSISIGAASIVAKVTRDRMMVEYDNIYPGYGFASNKGYGSAEHIKALKKIGP
SPIHRASFIHNFI

Sequences:

>Translated_253_residues
MSAEKIGDIKEQLKSITDSQLAQFIEAYGSDERGGVIKLVDSAKKRLDKYEKELIRTEGLKKYEREYASYAHICGIDEVG
RGPLAGPVVACAVILPKDCDILYINDSKKLTAAKRDELYDVIMEKAVSVGIGMASHERIDEINILQATYEAMRQAIGKLD
PAPDLTLNDAVTIPGVDIKQVPIIKGDAKSISIGAASIVAKVTRDRMMVEYDNIYPGYGFASNKGYGSAEHIKALKKIGP
SPIHRASFIHNFI
>Mature_252_residues
SAEKIGDIKEQLKSITDSQLAQFIEAYGSDERGGVIKLVDSAKKRLDKYEKELIRTEGLKKYEREYASYAHICGIDEVGR
GPLAGPVVACAVILPKDCDILYINDSKKLTAAKRDELYDVIMEKAVSVGIGMASHERIDEINILQATYEAMRQAIGKLDP
APDLTLNDAVTIPGVDIKQVPIIKGDAKSISIGAASIVAKVTRDRMMVEYDNIYPGYGFASNKGYGSAEHIKALKKIGPS
PIHRASFIHNFI

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family [H]

Homologues:

Organism=Escherichia coli, GI1786380, Length=182, Percent_Identity=46.1538461538462, Blast_Score=152, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01351 RNase_HII [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 27730; Mature: 27599

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAEKIGDIKEQLKSITDSQLAQFIEAYGSDERGGVIKLVDSAKKRLDKYEKELIRTEGL
CCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
KKYEREYASYAHICGIDEVGRGPLAGPVVACAVILPKDCDILYINDSKKLTAAKRDELYD
HHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHH
VIMEKAVSVGIGMASHERIDEINILQATYEAMRQAIGKLDPAPDLTLNDAVTIPGVDIKQ
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCC
VPIIKGDAKSISIGAASIVAKVTRDRMMVEYDNIYPGYGFASNKGYGSAEHIKALKKIGP
CCEEECCCCEEEHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCC
SPIHRASFIHNFI
CCHHHHHHHHHCC
>Mature Secondary Structure 
SAEKIGDIKEQLKSITDSQLAQFIEAYGSDERGGVIKLVDSAKKRLDKYEKELIRTEGL
CHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
KKYEREYASYAHICGIDEVGRGPLAGPVVACAVILPKDCDILYINDSKKLTAAKRDELYD
HHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHH
VIMEKAVSVGIGMASHERIDEINILQATYEAMRQAIGKLDPAPDLTLNDAVTIPGVDIKQ
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCC
VPIIKGDAKSISIGAASIVAKVTRDRMMVEYDNIYPGYGFASNKGYGSAEHIKALKKIGP
CCEEECCCCEEEHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCC
SPIHRASFIHNFI
CCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA