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The map label for this gene is yrvM [H]

Identifier: 238923742

GI number: 238923742

Start: 1236703

End: 1237464

Strand: Direct

Name: yrvM [H]

Synonym: EUBREC_1364

Alternate gene names: 238923742

Gene position: 1236703-1237464 (Clockwise)

Preceding gene: 238923741

Following gene: 238923743

Centisome position: 35.85

GC content: 47.51

Gene sequence:

>762_bases
ATGTTAAATCAGTTTTCAAGAACACAGCTTTTGCTTGGAAAAGAGGCGATGGATAGGCTAAAGGGCGCAAGAGTCGCAGT
ATTTGGAATAGGAGGAGTGGGCGGATATGTCTGCGAGGCACTAGTCAGAAGCGGCGTGGGAGCGATTGACCTTATCGATG
ATGACAAGGTGTGTCTTACAAACCTAAACAGGCAGATAATCGCAACCCGAAAGACCATAGGAAAATACAAGACAGATGTG
ATGGAGGAGAGGATTCAAGATATTAATCCTGATGTCAGTGTCGTGACGCACAGGTGCTTCTTTTTGCCGGAAAATGCTGA
TGAATTTCCGTTTGAAGAGTATGATTATATAGTTGACGCGGTTGATACGGTCACGGCAAAGATTGCGCTTGTCATGAAGG
CACAGGAGAAAAATGTCCCTATCATAAGCAGCATGGGAGCGGGAAATAAGCTGGATGCAAGTGCATTTAAGGTGGCTGAT
ATATATAAGACCAGCATGTGTCCTCTTGCAAAGGTCATGCGCCGTGAGCTTAAAAAACGTGGCGTGAAAAAGCTCAAGGT
GGTATACTCTGAGGAGAAGCCTACAAGACCGATAGAGGATATGTCTATAAGCTGCAGAAGCAACTGCATCTGCCCGCCGG
GTGCCGAACACAAGTGCACGCAGCGCAGGGATATTCCCGGAAGCCTTGCATTTGTACCATCAGTGGCAGGACTTATCATC
GCGGGCGAGGTGGTACAGGACATAGCCTTTGACAGGGTATGA

Upstream 100 bases:

>100_bases
CGATGATCTGTCAAAGGCTGACTGGAGCATGCTTAAGGATACAGTAAGACTCCTGATTTCTGCCGGTGTCGGCGTGGTCA
GGGATGAAAAGGAGAAATAA

Downstream 100 bases:

>100_bases
TGAAGAATACAATTACGAAAAGAGAGGAATAAAAATGCCAGTATTTGATTTTAGCGATACACCGGTAGCAAACGAGCATC
CGGAGTGTACATATGAGACA

Product: molybdopterin biosynthesis protein (MoeB) or thiamin-thiazole moiety synthesis (ThiF)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MLNQFSRTQLLLGKEAMDRLKGARVAVFGIGGVGGYVCEALVRSGVGAIDLIDDDKVCLTNLNRQIIATRKTIGKYKTDV
MEERIQDINPDVSVVTHRCFFLPENADEFPFEEYDYIVDAVDTVTAKIALVMKAQEKNVPIISSMGAGNKLDASAFKVAD
IYKTSMCPLAKVMRRELKKRGVKKLKVVYSEEKPTRPIEDMSISCRSNCICPPGAEHKCTQRRDIPGSLAFVPSVAGLII
AGEVVQDIAFDRV

Sequences:

>Translated_253_residues
MLNQFSRTQLLLGKEAMDRLKGARVAVFGIGGVGGYVCEALVRSGVGAIDLIDDDKVCLTNLNRQIIATRKTIGKYKTDV
MEERIQDINPDVSVVTHRCFFLPENADEFPFEEYDYIVDAVDTVTAKIALVMKAQEKNVPIISSMGAGNKLDASAFKVAD
IYKTSMCPLAKVMRRELKKRGVKKLKVVYSEEKPTRPIEDMSISCRSNCICPPGAEHKCTQRRDIPGSLAFVPSVAGLII
AGEVVQDIAFDRV
>Mature_253_residues
MLNQFSRTQLLLGKEAMDRLKGARVAVFGIGGVGGYVCEALVRSGVGAIDLIDDDKVCLTNLNRQIIATRKTIGKYKTDV
MEERIQDINPDVSVVTHRCFFLPENADEFPFEEYDYIVDAVDTVTAKIALVMKAQEKNVPIISSMGAGNKLDASAFKVAD
IYKTSMCPLAKVMRRELKKRGVKKLKVVYSEEKPTRPIEDMSISCRSNCICPPGAEHKCTQRRDIPGSLAFVPSVAGLII
AGEVVQDIAFDRV

Specific function: Unknown

COG id: COG1179

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI4885649, Length=138, Percent_Identity=32.6086956521739, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1789177, Length=209, Percent_Identity=39.2344497607655, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI87082356, Length=153, Percent_Identity=31.3725490196078, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787048, Length=131, Percent_Identity=31.2977099236641, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17540406, Length=172, Percent_Identity=26.7441860465116, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321790, Length=256, Percent_Identity=29.296875, Blast_Score=116, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6322825, Length=199, Percent_Identity=35.1758793969849, Blast_Score=93, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6321903, Length=149, Percent_Identity=28.1879194630872, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6325438, Length=152, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24660640, Length=129, Percent_Identity=32.5581395348837, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24582879, Length=152, Percent_Identity=26.9736842105263, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 27891; Mature: 27891

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNQFSRTQLLLGKEAMDRLKGARVAVFGIGGVGGYVCEALVRSGVGAIDLIDDDKVCLT
CCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHCCCCEEEEECCCCHHHH
NLNRQIIATRKTIGKYKTDVMEERIQDINPDVSVVTHRCFFLPENADEFPFEEYDYIVDA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEEECCCCCCCCCCHHHHHHHHH
VDTVTAKIALVMKAQEKNVPIISSMGAGNKLDASAFKVADIYKTSMCPLAKVMRRELKKR
HHHHHHHHHHEEECCCCCCCEEECCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHC
GVKKLKVVYSEEKPTRPIEDMSISCRSNCICPPGAEHKCTQRRDIPGSLAFVPSVAGLII
CHHHHHHEECCCCCCCCHHHCEEHHCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHH
AGEVVQDIAFDRV
HHHHHHHHHHCCC
>Mature Secondary Structure
MLNQFSRTQLLLGKEAMDRLKGARVAVFGIGGVGGYVCEALVRSGVGAIDLIDDDKVCLT
CCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHCCCCEEEEECCCCHHHH
NLNRQIIATRKTIGKYKTDVMEERIQDINPDVSVVTHRCFFLPENADEFPFEEYDYIVDA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEEECCCCCCCCCCHHHHHHHHH
VDTVTAKIALVMKAQEKNVPIISSMGAGNKLDASAFKVADIYKTSMCPLAKVMRRELKKR
HHHHHHHHHHEEECCCCCCCEEECCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHC
GVKKLKVVYSEEKPTRPIEDMSISCRSNCICPPGAEHKCTQRRDIPGSLAFVPSVAGLII
CHHHHHHEECCCCCCCCHHHCEEHHCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHH
AGEVVQDIAFDRV
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]