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The map label for this gene is yggV [C]

Identifier: 238923301

GI number: 238923301

Start: 818500

End: 819093

Strand: Direct

Name: yggV [C]

Synonym: EUBREC_0912

Alternate gene names: 238923301

Gene position: 818500-819093 (Clockwise)

Preceding gene: 238923300

Following gene: 238923302

Centisome position: 23.73

GC content: 47.14

Gene sequence:

>594_bases
ATGACAAAAATCATATTTGCAACAGGAAACAAGGATAAGCTCAGAGAAATCAAAGAGATACTTTCAGACTGTGACGTGGA
TATCCGTTCAATGAAGGAAGCAGGTATCAATGTGGATATAGTGGAGGATGGGAAGACCTTTGAAGACAATGCGCTGATTA
AGGCCCGCGCAATTGCGGCACACACAGATGCAATTGTTCTCGCAGACGACTCAGGACTTGAGATTGACTATCTGAATAAG
GAACCGGGAGTATATTCAGCGCGCTATATGGGCGAGGATACTTCCTATGATATAAAGAATAATAACCTTATAGAACGCCT
TGACGGTGTGCCAAAGGAGAAGCGTACAGCCCGCTTTGTGTGCGCTATCGCCGCAGTGCTGCCGGATGGAAAGGAACTTG
TGACCAGACAGACTATGGAGGGCTACATAGGATGGGAGATAGCGGGAGCCAACGGCTTTGGTTATGATCCTATCTTCTAT
TTAGATGAGTACGGCTGCTCTTCTGCAGAGCTTACTCCCCAGCAGAAGAATGCCATAAGCCATCGAGGCAAGGCTCTTCG
CGCCATGAGAGAAATGCTTGTGAAGGTGATCTAG

Upstream 100 bases:

>100_bases
AGCTCAGGGTATATACAATGCAATCATGCAGGCCTTTGATGAGGGCTACTAGCTGTATCTGGAAATTGTCCGAATAGAAA
AAGAAGGAAGGAAATATATT

Downstream 100 bases:

>100_bases
AGTATAGGCGTTCAATTGCAACGTATACGGATAAAATGCCTGCCGGTAAGCTCTTTTAAGCTGTCCGGCAGCCACTTTTA
AAAAAATATAAAAAAAATAA

Product: ribonuclease Ph

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MTKIIFATGNKDKLREIKEILSDCDVDIRSMKEAGINVDIVEDGKTFEDNALIKARAIAAHTDAIVLADDSGLEIDYLNK
EPGVYSARYMGEDTSYDIKNNNLIERLDGVPKEKRTARFVCAIAAVLPDGKELVTRQTMEGYIGWEIAGANGFGYDPIFY
LDEYGCSSAELTPQQKNAISHRGKALRAMREMLVKVI

Sequences:

>Translated_197_residues
MTKIIFATGNKDKLREIKEILSDCDVDIRSMKEAGINVDIVEDGKTFEDNALIKARAIAAHTDAIVLADDSGLEIDYLNK
EPGVYSARYMGEDTSYDIKNNNLIERLDGVPKEKRTARFVCAIAAVLPDGKELVTRQTMEGYIGWEIAGANGFGYDPIFY
LDEYGCSSAELTPQQKNAISHRGKALRAMREMLVKVI
>Mature_196_residues
TKIIFATGNKDKLREIKEILSDCDVDIRSMKEAGINVDIVEDGKTFEDNALIKARAIAAHTDAIVLADDSGLEIDYLNKE
PGVYSARYMGEDTSYDIKNNNLIERLDGVPKEKRTARFVCAIAAVLPDGKELVTRQTMEGYIGWEIAGANGFGYDPIFYL
DEYGCSSAELTPQQKNAISHRGKALRAMREMLVKVI

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=196, Percent_Identity=44.3877551020408, Blast_Score=154, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21885; Mature: 21754

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIIFATGNKDKLREIKEILSDCDVDIRSMKEAGINVDIVEDGKTFEDNALIKARAIAA
CCEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEECCCCCCCCCEEEEEEEEE
HTDAIVLADDSGLEIDYLNKEPGVYSARYMGEDTSYDIKNNNLIERLDGVPKEKRTARFV
CCCEEEEECCCCCEEEEECCCCCCEEEEECCCCCCEECCCCCHHHHHCCCCCHHHHHHHH
CAIAAVLPDGKELVTRQTMEGYIGWEIAGANGFGYDPIFYLDEYGCSSAELTPQQKNAIS
HHHHHHCCCCHHHHHHHHHCCEEEEEEECCCCCCCCCEEEEECCCCCCCCCCCHHHHHHH
HRGKALRAMREMLVKVI
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKIIFATGNKDKLREIKEILSDCDVDIRSMKEAGINVDIVEDGKTFEDNALIKARAIAA
CEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEECCCCCCCCCEEEEEEEEE
HTDAIVLADDSGLEIDYLNKEPGVYSARYMGEDTSYDIKNNNLIERLDGVPKEKRTARFV
CCCEEEEECCCCCEEEEECCCCCCEEEEECCCCCCEECCCCCHHHHHCCCCCHHHHHHHH
CAIAAVLPDGKELVTRQTMEGYIGWEIAGANGFGYDPIFYLDEYGCSSAELTPQQKNAIS
HHHHHHCCCCHHHHHHHHHCCEEEEEEECCCCCCCCCEEEEECCCCCCCCCCCHHHHHHH
HRGKALRAMREMLVKVI
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792842 [H]