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The map label for this gene is apeA [H]

Identifier: 238923103

GI number: 238923103

Start: 638066

End: 639475

Strand: Direct

Name: apeA [H]

Synonym: EUBREC_0695

Alternate gene names: 238923103

Gene position: 638066-639475 (Clockwise)

Preceding gene: 238923102

Following gene: 238923104

Centisome position: 18.5

GC content: 47.66

Gene sequence:

>1410_bases
ATGGCAATAGAAAAGAAAAACGCCTGGGAGAAATATCCCCAGGGACCTGAAAGAGAAAAATTATTTGCATTTGCAGAGGA
TTACAGAAGGTTTATATCCGGCTGCAAGACAGAGCGCGAGTGCACGGCATCAGTTTATGCTGACGCCACAGGACACGGCT
TTGTAGACCTTGATGAGCTCATCGAGACAGGAAAGAGCGTAAAGGCAGGAGATAAAATCATAGCAAACAATATGGGAAAG
GGACTGGCGCTGTTTATCGTGGGCAGTAAGCCTCTTGAGAAGGGTATGAATATCCTCGGAGCTCATATTGATTCACCTAG
AATGGACTTAAAGCAGGTGCCTTTATACGAGGACACAGACATGGCACTTTTAGACACACATTATTATGGCGGTATCAAGA
AATACCAGTGGGTCACACTGCCGCTTGCACTTCACGGAGTCATCTGTAAAAAGGATGGCAGCACAGTGACAGTCAATATC
GGAGACAAGCCAAATGATCCTGTAGTGGGTGTGAGCGATCTGCTTATTCACCTGTCAGGCGAGCAGATGGGCAAGAAGGC
CTCAGAGGTCATAAAGGGCGAGAGCCTTGATGTGCTGATCGGAAGCATACCGGGACCAGAAAAGGACGAGGACGACAAGG
ATATCAAGGAGAGAGTAAAGGCCAATATCCTCACAATACTTTCACAGGAGTACGGTGTGGACGAGGATGATTTCCTTTCA
GCAGAGATAGAGGTGGTACCTGCCGGAGAGGCAAGAGACTACGGACTTGACAGAAGTATGATCATGGGTTACGGCCATGA
CGACAGAGTGTGCGCATATCCTTCATACAGAGCTATGCTTGAAATAGATGGCGCACCGGAATATACAAGTGTATGCCTGC
TCGTGGACAAAGAGGAAATCGGCTCAGTGGGAGCCAGCGGCATGCAGTCACGCTTTTTTGAAAACTGTGTGGCAGAGGTG
ATGAACCTGGCAGGAGACTACAGCGAGCTTGCAGTCAGACGTGCACTGAAAAACTCAAAGGTACTCTCATCAGACGTATC
AGCAGCCTTTGACCCGAATTATCCATCGGTTATGGAAAAGAAGAACTCGGCATACTTTGGAAAGGGCCTTGTATTCAACA
AATATACAGGCGCCAGAGGCAAATCAGGCTCAAACGATGCCAACGCAGAGTATGTTGCAAGGCTTAGAAATATCATGGAT
ACAGCAGATGTTTCATTCCAGACAGCAGAGCTTGGAAAGGTAGACGAGGGAGGCGGCGGAACAATCGCATATATCCTCGC
AAACTATGACATGAATGTTATTGACAGCGGTGTGCCGGTGCTCAACATGCATGCGCCATGGGAAATCATCAGCAAGGTCG
ATTTATATGAGGCATTCAGAGGCTACATTGCATTTTTGAAGGAAGCATAG

Upstream 100 bases:

>100_bases
AGTCAATCACAGACAAAAAAAGATGGGCTACAATGCAGCTCAGGAGCTGTATCGCCGCGTCCAGGCAAATCTTACAAAAA
ATTCGGAGGTATAATAAATC

Downstream 100 bases:

>100_bases
GCTAAAGGAATATAAGATGAATCAGACATTTGTAAAAAGTGTAACAGAACAATTGCCGCAGCTTGGTCTCCTGCAGGATG
AGCCGATGAAAAAACACACG

Product: putative aminopeptidase 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MAIEKKNAWEKYPQGPEREKLFAFAEDYRRFISGCKTERECTASVYADATGHGFVDLDELIETGKSVKAGDKIIANNMGK
GLALFIVGSKPLEKGMNILGAHIDSPRMDLKQVPLYEDTDMALLDTHYYGGIKKYQWVTLPLALHGVICKKDGSTVTVNI
GDKPNDPVVGVSDLLIHLSGEQMGKKASEVIKGESLDVLIGSIPGPEKDEDDKDIKERVKANILTILSQEYGVDEDDFLS
AEIEVVPAGEARDYGLDRSMIMGYGHDDRVCAYPSYRAMLEIDGAPEYTSVCLLVDKEEIGSVGASGMQSRFFENCVAEV
MNLAGDYSELAVRRALKNSKVLSSDVSAAFDPNYPSVMEKKNSAYFGKGLVFNKYTGARGKSGSNDANAEYVARLRNIMD
TADVSFQTAELGKVDEGGGGTIAYILANYDMNVIDSGVPVLNMHAPWEIISKVDLYEAFRGYIAFLKEA

Sequences:

>Translated_469_residues
MAIEKKNAWEKYPQGPEREKLFAFAEDYRRFISGCKTERECTASVYADATGHGFVDLDELIETGKSVKAGDKIIANNMGK
GLALFIVGSKPLEKGMNILGAHIDSPRMDLKQVPLYEDTDMALLDTHYYGGIKKYQWVTLPLALHGVICKKDGSTVTVNI
GDKPNDPVVGVSDLLIHLSGEQMGKKASEVIKGESLDVLIGSIPGPEKDEDDKDIKERVKANILTILSQEYGVDEDDFLS
AEIEVVPAGEARDYGLDRSMIMGYGHDDRVCAYPSYRAMLEIDGAPEYTSVCLLVDKEEIGSVGASGMQSRFFENCVAEV
MNLAGDYSELAVRRALKNSKVLSSDVSAAFDPNYPSVMEKKNSAYFGKGLVFNKYTGARGKSGSNDANAEYVARLRNIMD
TADVSFQTAELGKVDEGGGGTIAYILANYDMNVIDSGVPVLNMHAPWEIISKVDLYEAFRGYIAFLKEA
>Mature_468_residues
AIEKKNAWEKYPQGPEREKLFAFAEDYRRFISGCKTERECTASVYADATGHGFVDLDELIETGKSVKAGDKIIANNMGKG
LALFIVGSKPLEKGMNILGAHIDSPRMDLKQVPLYEDTDMALLDTHYYGGIKKYQWVTLPLALHGVICKKDGSTVTVNIG
DKPNDPVVGVSDLLIHLSGEQMGKKASEVIKGESLDVLIGSIPGPEKDEDDKDIKERVKANILTILSQEYGVDEDDFLSA
EIEVVPAGEARDYGLDRSMIMGYGHDDRVCAYPSYRAMLEIDGAPEYTSVCLLVDKEEIGSVGASGMQSRFFENCVAEVM
NLAGDYSELAVRRALKNSKVLSSDVSAAFDPNYPSVMEKKNSAYFGKGLVFNKYTGARGKSGSNDANAEYVARLRNIMDT
ADVSFQTAELGKVDEGGGGTIAYILANYDMNVIDSGVPVLNMHAPWEIISKVDLYEAFRGYIAFLKEA

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=470, Percent_Identity=23.1914893617021, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17552916, Length=468, Percent_Identity=24.1452991452991, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6321905, Length=474, Percent_Identity=23.8396624472574, Blast_Score=83, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6322746, Length=441, Percent_Identity=22.6757369614512, Blast_Score=76, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022983
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 51331; Mature: 51199

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIEKKNAWEKYPQGPEREKLFAFAEDYRRFISGCKTERECTASVYADATGHGFVDLDEL
CCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHEEECCCCCCCEEHHHH
IETGKSVKAGDKIIANNMGKGLALFIVGSKPLEKGMNILGAHIDSPRMDLKQVPLYEDTD
HHCCCCCCCCCHHHHCCCCCCEEEEEECCCCHHHCHHHEECCCCCCCCCHHHCCCCCCCC
MALLDTHYYGGIKKYQWVTLPLALHGVICKKDGSTVTVNIGDKPNDPVVGVSDLLIHLSG
CEEEEHHHHCCCCEEEEEEEEHEEEEEEEECCCCEEEEECCCCCCCCEEEHHHHEEEECC
EQMGKKASEVIKGESLDVLIGSIPGPEKDEDDKDIKERVKANILTILSQEYGVDEDDFLS
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
AEIEVVPAGEARDYGLDRSMIMGYGHDDRVCAYPSYRAMLEIDGAPEYTSVCLLVDKEEI
EEEEEEECCCCCCCCCCCHHEEECCCCCCEEECCCCEEEEEECCCCCCEEEEEEEEHHHH
GSVGASGMQSRFFENCVAEVMNLAGDYSELAVRRALKNSKVLSSDVSAAFDPNYPSVMEK
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHC
KNSAYFGKGLVFNKYTGARGKSGSNDANAEYVARLRNIMDTADVSFQTAELGKVDEGGGG
CCCCEECCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEHHCCCCCCCCCC
TIAYILANYDMNVIDSGVPVLNMHAPWEIISKVDLYEAFRGYIAFLKEA
EEEEEEECCCCHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AIEKKNAWEKYPQGPEREKLFAFAEDYRRFISGCKTERECTASVYADATGHGFVDLDEL
CCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHEEECCCCCCCEEHHHH
IETGKSVKAGDKIIANNMGKGLALFIVGSKPLEKGMNILGAHIDSPRMDLKQVPLYEDTD
HHCCCCCCCCCHHHHCCCCCCEEEEEECCCCHHHCHHHEECCCCCCCCCHHHCCCCCCCC
MALLDTHYYGGIKKYQWVTLPLALHGVICKKDGSTVTVNIGDKPNDPVVGVSDLLIHLSG
CEEEEHHHHCCCCEEEEEEEEHEEEEEEEECCCCEEEEECCCCCCCCEEEHHHHEEEECC
EQMGKKASEVIKGESLDVLIGSIPGPEKDEDDKDIKERVKANILTILSQEYGVDEDDFLS
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
AEIEVVPAGEARDYGLDRSMIMGYGHDDRVCAYPSYRAMLEIDGAPEYTSVCLLVDKEEI
EEEEEEECCCCCCCCCCCHHEEECCCCCCEEECCCCEEEEEECCCCCCEEEEEEEEHHHH
GSVGASGMQSRFFENCVAEVMNLAGDYSELAVRRALKNSKVLSSDVSAAFDPNYPSVMEK
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHC
KNSAYFGKGLVFNKYTGARGKSGSNDANAEYVARLRNIMDTADVSFQTAELGKVDEGGGG
CCCCEECCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEHHCCCCCCCCCC
TIAYILANYDMNVIDSGVPVLNMHAPWEIISKVDLYEAFRGYIAFLKEA
EEEEEEECCCCHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]