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The map label for this gene is hprK [H]

Identifier: 238923102

GI number: 238923102

Start: 637118

End: 638059

Strand: Direct

Name: hprK [H]

Synonym: EUBREC_0694

Alternate gene names: 238923102

Gene position: 637118-638059 (Clockwise)

Preceding gene: 238923101

Following gene: 238923103

Centisome position: 18.47

GC content: 47.24

Gene sequence:

>942_bases
ATGGATGCATTACACTCAGTATCAGTTGCAAAGGTAGCAGAATTGCTCGATCTCAACAATCTCACAAAAGAGATGAACCT
AAAGGAGAGGGCGATAGAGTGCTCGGACGTCAACAGACCGGCGCTTCAGCTCTCAGGATATTTTGATCATTTTGAGGAGA
GACGAATACAGATTATCGGAAATGTAGAGTATACCTATATAGAGAAGATGAGCGACAGCGAGAAAAAAGAGCGCTATAGC
CGCTTCATGGAGTTTGATATACCATGTATCATCTTCTGCAGAGATTTACAGCCGGATGAGATATTTATGGAAGAGGCCAG
AGAGCACGGTATTCCGGTGCTGTCAACAGGTCGTTCCACATCAAGCTTTATGGCTGAGCTCATCTATTGTCTTGGTGAGC
AGCTCGCACCATGCATCACAGTGCACGGCGTGCTGGTAGATGTATACGGCGAGGGAGTAATGATCACAGGCGAGAGCGGT
ATCGGAAAGAGTGAGGCTGCACTCGAGCTCATCAGACGAGGACATCGTCTTGTGACGGATGATGTGGTGGAAATCAGAAA
GATCAACGAGCATACGCTCATGGGTACTTCGCCTGAGATTACCAGACACTTTATAGAGCTTCGTGGCATCGGAATCATCG
ATGTCAAGACACTTTACGGAGTAGAGTGTGTAAAGGAAAAACAGCAGATAGACCTCGTAATCAAGCTCGAGGACTGGAAG
AAGGAGGCAGATTACGACAGACTCGGCCTCGAGGAAGAATATGCCGAGTATCTCGGCAACAAAGTAGTGTGTCATTCACT
GCCAATCAGACCGGGACGTAATCTGGCAGTCATCGTAGAGACAGCAGCAGTCAATCACAGACAAAAAAAGATGGGCTACA
ATGCAGCTCAGGAGCTGTATCGCCGCGTCCAGGCAAATCTTACAAAAAATTCGGAGGTATAA

Upstream 100 bases:

>100_bases
GCAGCACAGGCAGTGTATGCATTTTTCCACTCTGCCACGTAGATTTTGAAGCTAATCTGTGGTATACTAAAAAACAAATA
TACATCAAGGGGGACCGCGA

Downstream 100 bases:

>100_bases
TAAATCATGGCAATAGAAAAGAAAAACGCCTGGGAGAAATATCCCCAGGGACCTGAAAGAGAAAAATTATTTGCATTTGC
AGAGGATTACAGAAGGTTTA

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MDALHSVSVAKVAELLDLNNLTKEMNLKERAIECSDVNRPALQLSGYFDHFEERRIQIIGNVEYTYIEKMSDSEKKERYS
RFMEFDIPCIIFCRDLQPDEIFMEEAREHGIPVLSTGRSTSSFMAELIYCLGEQLAPCITVHGVLVDVYGEGVMITGESG
IGKSEAALELIRRGHRLVTDDVVEIRKINEHTLMGTSPEITRHFIELRGIGIIDVKTLYGVECVKEKQQIDLVIKLEDWK
KEADYDRLGLEEEYAEYLGNKVVCHSLPIRPGRNLAVIVETAAVNHRQKKMGYNAAQELYRRVQANLTKNSEV

Sequences:

>Translated_313_residues
MDALHSVSVAKVAELLDLNNLTKEMNLKERAIECSDVNRPALQLSGYFDHFEERRIQIIGNVEYTYIEKMSDSEKKERYS
RFMEFDIPCIIFCRDLQPDEIFMEEAREHGIPVLSTGRSTSSFMAELIYCLGEQLAPCITVHGVLVDVYGEGVMITGESG
IGKSEAALELIRRGHRLVTDDVVEIRKINEHTLMGTSPEITRHFIELRGIGIIDVKTLYGVECVKEKQQIDLVIKLEDWK
KEADYDRLGLEEEYAEYLGNKVVCHSLPIRPGRNLAVIVETAAVNHRQKKMGYNAAQELYRRVQANLTKNSEV
>Mature_313_residues
MDALHSVSVAKVAELLDLNNLTKEMNLKERAIECSDVNRPALQLSGYFDHFEERRIQIIGNVEYTYIEKMSDSEKKERYS
RFMEFDIPCIIFCRDLQPDEIFMEEAREHGIPVLSTGRSTSSFMAELIYCLGEQLAPCITVHGVLVDVYGEGVMITGESG
IGKSEAALELIRRGHRLVTDDVVEIRKINEHTLMGTSPEITRHFIELRGIGIIDVKTLYGVECVKEKQQIDLVIKLEDWK
KEADYDRLGLEEEYAEYLGNKVVCHSLPIRPGRNLAVIVETAAVNHRQKKMGYNAAQELYRRVQANLTKNSEV

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126 [H]

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N [H]

EC number: NA

Molecular weight: Translated: 35683; Mature: 35683

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDALHSVSVAKVAELLDLNNLTKEMNLKERAIECSDVNRPALQLSGYFDHFEERRIQIIG
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCEEECHHHHHHHCCEEEEEE
NVEYTYIEKMSDSEKKERYSRFMEFDIPCIIFCRDLQPDEIFMEEAREHGIPVLSTGRST
CCCEEHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCEEECCCCH
SSFMAELIYCLGEQLAPCITVHGVLVDVYGEGVMITGESGIGKSEAALELIRRGHRLVTD
HHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEECCCCCCCHHHHHHHHHCCCCCHHH
DVVEIRKINEHTLMGTSPEITRHFIELRGIGIIDVKTLYGVECVKEKQQIDLVIKLEDWK
HHHHHHHCCCCEECCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCEEEEEEEECCC
KEADYDRLGLEEEYAEYLGNKVVCHSLPIRPGRNLAVIVETAAVNHRQKKMGYNAAQELY
CCCCHHHCCCHHHHHHHCCCEEEEEECCCCCCCCEEEEEEEHHHHHHHHHCCCHHHHHHH
RRVQANLTKNSEV
HHHHHCCCCCCCC
>Mature Secondary Structure
MDALHSVSVAKVAELLDLNNLTKEMNLKERAIECSDVNRPALQLSGYFDHFEERRIQIIG
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCEEECHHHHHHHCCEEEEEE
NVEYTYIEKMSDSEKKERYSRFMEFDIPCIIFCRDLQPDEIFMEEAREHGIPVLSTGRST
CCCEEHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCEEECCCCH
SSFMAELIYCLGEQLAPCITVHGVLVDVYGEGVMITGESGIGKSEAALELIRRGHRLVTD
HHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEECCCCCCCHHHHHHHHHCCCCCHHH
DVVEIRKINEHTLMGTSPEITRHFIELRGIGIIDVKTLYGVECVKEKQQIDLVIKLEDWK
HHHHHHHCCCCEECCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCEEEEEEEECCC
KEADYDRLGLEEEYAEYLGNKVVCHSLPIRPGRNLAVIVETAAVNHRQKKMGYNAAQELY
CCCCHHHCCCHHHHHHHCCCEEEEEECCCCCCCCEEEEEEEHHHHHHHHHCCCHHHHHHH
RRVQANLTKNSEV
HHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA