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The map label for this gene is murA3 [H]

Identifier: 238922873

GI number: 238922873

Start: 417209

End: 418501

Strand: Direct

Name: murA3 [H]

Synonym: EUBREC_0461

Alternate gene names: 238922873

Gene position: 417209-418501 (Clockwise)

Preceding gene: 238922872

Following gene: 238922875

Centisome position: 12.09

GC content: 46.17

Gene sequence:

>1293_bases
ATGGAACAGTACGTAATCAAAGGTGGAAATCCTTTATACGGTGAAGTTGAAATTGGTGGAGCCAAAAATGCTGCACTTGC
TATTTTGGCCGCTGCCATAATGACAGACGAGACTGTAACAATAGATAATTTGCCAAATGTAAGGGATATCAATGTCTTAC
TTCAGGCAATCGAAGAAATCGGCGCACATGTGGAGCGCGTGGATATACACAAGGTAAAGATAAACGGTTCATTTATCAGG
GGCGTAAATGTCGATAATGAATTCATCAGACGAATCAGGGCATCATATTATTTAATTGGTGCATTACTTGGAAAATACAA
GCATGCAGAGGTTGCGCTTCCGGGAGGCTGTGATATCGGAAGCAGGCCGATTGACCTTCATATGAAGGGCTTCCGCTCCA
TGGGAGCAGACATAGACATAGCTCATGGCCTTGTCATCGCCAGGGCAAAGGAGCTTAAGGGCACACATATATATATGGAT
AAGGTTTCTGTAGGTGCCACAATCAATATTATGATGGCTGCAGCCATGGCAGATGGCAAGACTGTTATCGAGAATGCGGC
TAAGGAGCCTCATGTCGTTGATGTGGCAAACTTCTTAAACAGCATGGGAGCAAATATCAGGGGCGCAGGAACCGATGTCA
TCAGAATTGTAGGTGTGGAGAAATTACATGCTACAGAGTATTCTGTCATTCCGGATCAGATTGAGGCCGGTACATTCATG
TTTGCAGTTGCGGCAGCGGGAGGCAACGTGCTGGTAAAGAATGTCATTCCAAAGCATCTTGAGGCCACCACAGCAAAGCT
GTTGGAGGTAGGCTGCCAGGTAGAGGAGTTTGATGACTCAGTCAGAGTAATATCAGATGGACATTTAAAGCATACACAGG
TCACCACACTTCCATATCCGGGCTTCCCGACAGATATGCAGCCACAGATGGCGGTGCTTTTGGGTATCGCTGAGGGCACC
AGTACAGTGACAGAGAGCATATTTGAGAATCGTTTCAAGTATGTTGACGAGCTCACCAGAATGGGAGCTGATATAAAGGT
AGAGAGCAATATAGCAATCATCAGCGGCGTGAAAAGATACACAGGTGCCAGAGTGAATGCACCTGACCTAAGAGCAGGAG
CTGCACTGGTTATAGCAGGTCTTGCAGCAGAGGGCATCACAGTGGTTGATGATATCTACTATATCCAGAGAGGCTATGAG
GCACTCGAGGAGAAGCTTACAAAGATTGGTGCAAAGATTGCCAGGGTAGAGGATGAGAAGGAGCTTCAGAAGTTCATACT
CAAGGTATCGTAA

Upstream 100 bases:

>100_bases
GTCGTCATAAATGAAATTTGTAGTTGGATGTATAACAATAGTGTAAATTGAGAATAGTATATTAGGAGGAAGTATACTCC
TGAATTCATAGAGGTGGAAT

Downstream 100 bases:

>100_bases
TAGATATATACGTAAAGCATGAAATGTAAACACAATATAAATGCAATATATAAAATAAGAACCGGCAGCATCTTACTGTA
GATGCACGGTTCTTATTTTT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 3; UDP-N-acetylglucosamine enolpyruvyl transferase 3; EPT 3 [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MEQYVIKGGNPLYGEVEIGGAKNAALAILAAAIMTDETVTIDNLPNVRDINVLLQAIEEIGAHVERVDIHKVKINGSFIR
GVNVDNEFIRRIRASYYLIGALLGKYKHAEVALPGGCDIGSRPIDLHMKGFRSMGADIDIAHGLVIARAKELKGTHIYMD
KVSVGATINIMMAAAMADGKTVIENAAKEPHVVDVANFLNSMGANIRGAGTDVIRIVGVEKLHATEYSVIPDQIEAGTFM
FAVAAAGGNVLVKNVIPKHLEATTAKLLEVGCQVEEFDDSVRVISDGHLKHTQVTTLPYPGFPTDMQPQMAVLLGIAEGT
STVTESIFENRFKYVDELTRMGADIKVESNIAIISGVKRYTGARVNAPDLRAGAALVIAGLAAEGITVVDDIYYIQRGYE
ALEEKLTKIGAKIARVEDEKELQKFILKVS

Sequences:

>Translated_430_residues
MEQYVIKGGNPLYGEVEIGGAKNAALAILAAAIMTDETVTIDNLPNVRDINVLLQAIEEIGAHVERVDIHKVKINGSFIR
GVNVDNEFIRRIRASYYLIGALLGKYKHAEVALPGGCDIGSRPIDLHMKGFRSMGADIDIAHGLVIARAKELKGTHIYMD
KVSVGATINIMMAAAMADGKTVIENAAKEPHVVDVANFLNSMGANIRGAGTDVIRIVGVEKLHATEYSVIPDQIEAGTFM
FAVAAAGGNVLVKNVIPKHLEATTAKLLEVGCQVEEFDDSVRVISDGHLKHTQVTTLPYPGFPTDMQPQMAVLLGIAEGT
STVTESIFENRFKYVDELTRMGADIKVESNIAIISGVKRYTGARVNAPDLRAGAALVIAGLAAEGITVVDDIYYIQRGYE
ALEEKLTKIGAKIARVEDEKELQKFILKVS
>Mature_430_residues
MEQYVIKGGNPLYGEVEIGGAKNAALAILAAAIMTDETVTIDNLPNVRDINVLLQAIEEIGAHVERVDIHKVKINGSFIR
GVNVDNEFIRRIRASYYLIGALLGKYKHAEVALPGGCDIGSRPIDLHMKGFRSMGADIDIAHGLVIARAKELKGTHIYMD
KVSVGATINIMMAAAMADGKTVIENAAKEPHVVDVANFLNSMGANIRGAGTDVIRIVGVEKLHATEYSVIPDQIEAGTFM
FAVAAAGGNVLVKNVIPKHLEATTAKLLEVGCQVEEFDDSVRVISDGHLKHTQVTTLPYPGFPTDMQPQMAVLLGIAEGT
STVTESIFENRFKYVDELTRMGADIKVESNIAIISGVKRYTGARVNAPDLRAGAALVIAGLAAEGITVVDDIYYIQRGYE
ALEEKLTKIGAKIARVEDEKELQKFILKVS

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=427, Percent_Identity=47.7751756440281, Blast_Score=385, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 46376; Mature: 46376

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQYVIKGGNPLYGEVEIGGAKNAALAILAAAIMTDETVTIDNLPNVRDINVLLQAIEEI
CCCEEEECCCEEEEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHH
GAHVERVDIHKVKINGSFIRGVNVDNEFIRRIRASYYLIGALLGKYKHAEVALPGGCDIG
CCCEEEEEEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCC
SRPIDLHMKGFRSMGADIDIAHGLVIARAKELKGTHIYMDKVSVGATINIMMAAAMADGK
CCCEEEEHHHHHHCCCCCCHHCCEEEEEHHHCCCCEEEEEEECCCCEEEEEEEEHHCCCH
TVIENAAKEPHVVDVANFLNSMGANIRGAGTDVIRIVGVEKLHATEYSVIPDQIEAGTFM
HHHHHCCCCCCEEHHHHHHHHHCCCCCCCCCCEEEEEEHHHHCCCCCCCCCCHHCCCEEE
FAVAAAGGNVLVKNVIPKHLEATTAKLLEVGCQVEEFDDSVRVISDGHLKHTQVTTLPYP
EEEEECCCCEEEEHHCHHHHHHHHHHHHHHCCCHHHCCCCEEEEECCCEEEEEEEECCCC
GFPTDMQPQMAVLLGIAEGTSTVTESIFENRFKYVDELTRMGADIKVESNIAIISGVKRY
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEECHHHH
TGARVNAPDLRAGAALVIAGLAAEGITVVDDIYYIQRGYEALEEKLTKIGAKIARVEDEK
CCCCCCCCCCCCCHHHEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ELQKFILKVS
HHHHHHHCCC
>Mature Secondary Structure
MEQYVIKGGNPLYGEVEIGGAKNAALAILAAAIMTDETVTIDNLPNVRDINVLLQAIEEI
CCCEEEECCCEEEEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHH
GAHVERVDIHKVKINGSFIRGVNVDNEFIRRIRASYYLIGALLGKYKHAEVALPGGCDIG
CCCEEEEEEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCC
SRPIDLHMKGFRSMGADIDIAHGLVIARAKELKGTHIYMDKVSVGATINIMMAAAMADGK
CCCEEEEHHHHHHCCCCCCHHCCEEEEEHHHCCCCEEEEEEECCCCEEEEEEEEHHCCCH
TVIENAAKEPHVVDVANFLNSMGANIRGAGTDVIRIVGVEKLHATEYSVIPDQIEAGTFM
HHHHHCCCCCCEEHHHHHHHHHCCCCCCCCCCEEEEEEHHHHCCCCCCCCCCHHCCCEEE
FAVAAAGGNVLVKNVIPKHLEATTAKLLEVGCQVEEFDDSVRVISDGHLKHTQVTTLPYP
EEEEECCCCEEEEHHCHHHHHHHHHHHHHHCCCHHHCCCCEEEEECCCEEEEEEEECCCC
GFPTDMQPQMAVLLGIAEGTSTVTESIFENRFKYVDELTRMGADIKVESNIAIISGVKRY
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEECHHHH
TGARVNAPDLRAGAALVIAGLAAEGITVVDDIYYIQRGYEALEEKLTKIGAKIARVEDEK
CCCCCCCCCCCCCHHHEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ELQKFILKVS
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]