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The map label for this gene is pheA [H]

Identifier: 238922191

GI number: 238922191

Start: 387736

End: 388878

Strand: Reverse

Name: pheA [H]

Synonym: EUBELI_20426

Alternate gene names: 238922191

Gene position: 388878-387736 (Counterclockwise)

Preceding gene: 238922193

Following gene: 238922190

Centisome position: 62.05

GC content: 36.05

Gene sequence:

>1143_bases
ATGTTAGACCTTAATGAAATACGAAATAATATTGATAAAATCGACAGTCAGCTTGTAGAACTGTTTGAAGAGAGAATGAA
ACTGACAACTGAGGTTGCAGAATATAAGATTGAGACAGGAAAGAAGGTTCTTGATCCGGCACGCGAGAAAGCTAAGTTAG
AATCTGTCAAGAAGCTTGTTAAGAATCCTGATAATGTGCATGCTATTGATGACCTGTTTGCACAGATTATGGCTAACTCA
AGAAAGAATCAGTATATGCTTCTTGAAAAGATGGGACAGACTTTAAGAGAGCCATATGAGGCTATTGATGAGATTAATAA
GAAAGATTGCAAGGTAGTATATCAGGGAGTTCCAGGTGCATATTCATATGCTGCCATGATTAATTTCTTTGGCAAGGATG
TTGATAATTTCAATGTTCCTACATGGAGAGAGTGCATGGAAGCAGTTAAGCAGGGGAAAGCTGATTATGCGGTTCTTCCT
ATAGAGAATTCCAATGCCGGAATTGTTGCTGATGTGTATGATTTGTTACAGGAATATAATAATTACATAATAGCAGAAAC
TTATGTTAAAATTGAACATTTGTTACTTGGACTTCCGGGAACTGACCTTGAAAATGTAACTGCTGTATATTCACATCCAC
AGGGACTTATGCAGTGTGACAGATTCTTAGATACTCACAAGGACTGGCAGAGAATAAGTCAGGCTAATACAGCACTTGCA
GCAAAGATGATTTTTCAGGAGCATAATAAGACCCATGTTGCCATTGCGAGTAAGGAAGCAGCAGAGCTTTATGGTCTTGA
TATCTTAAAGTCTGGAATTACAGATCAGGAGGGCAATACAACAAGATTTGTTATTGTTACTAATACAAGAAAGTTTGTTA
AGAATGCACAGAAGATGAGTATTGTGTTTGAAACAGCTAATGAAGCAGGCACTCTATATAATCTTTTAAGTCATATTATA
TATAATGGTCTTAATATGAATAAGATTGAATCAAGACCAATTGAGGGTAATGTAGAGGGAAAGAGATGGAATTTCCGTTT
CTTTGTTGATTTTACAGGTAATATTGATGATCCAAGAGTTATGAATGCATTAAGAGGTATTGAAGAGGAAGCTGAGTCAA
TTAAGTTGCTTGGAAACTATTAA

Upstream 100 bases:

>100_bases
TAAGAACATTTTCTTAAGTATAACATAAAGTACATTTATTGCATATCATTAAAAATGTGATACAATAAGAATAATACATC
GCTTTAAAGAGGAGAAGTAT

Downstream 100 bases:

>100_bases
TGTGTTAGAATTATGAAGATGTCGTCAGACAATAAGTTATTAGATAAGTGAGGAAATTAGAGTGAATTTAGAAGAAGCAA
AGCTTAAGCTTTCAAAGTAC

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MLDLNEIRNNIDKIDSQLVELFEERMKLTTEVAEYKIETGKKVLDPAREKAKLESVKKLVKNPDNVHAIDDLFAQIMANS
RKNQYMLLEKMGQTLREPYEAIDEINKKDCKVVYQGVPGAYSYAAMINFFGKDVDNFNVPTWRECMEAVKQGKADYAVLP
IENSNAGIVADVYDLLQEYNNYIIAETYVKIEHLLLGLPGTDLENVTAVYSHPQGLMQCDRFLDTHKDWQRISQANTALA
AKMIFQEHNKTHVAIASKEAAELYGLDILKSGITDQEGNTTRFVIVTNTRKFVKNAQKMSIVFETANEAGTLYNLLSHII
YNGLNMNKIESRPIEGNVEGKRWNFRFFVDFTGNIDDPRVMNALRGIEEEAESIKLLGNY

Sequences:

>Translated_380_residues
MLDLNEIRNNIDKIDSQLVELFEERMKLTTEVAEYKIETGKKVLDPAREKAKLESVKKLVKNPDNVHAIDDLFAQIMANS
RKNQYMLLEKMGQTLREPYEAIDEINKKDCKVVYQGVPGAYSYAAMINFFGKDVDNFNVPTWRECMEAVKQGKADYAVLP
IENSNAGIVADVYDLLQEYNNYIIAETYVKIEHLLLGLPGTDLENVTAVYSHPQGLMQCDRFLDTHKDWQRISQANTALA
AKMIFQEHNKTHVAIASKEAAELYGLDILKSGITDQEGNTTRFVIVTNTRKFVKNAQKMSIVFETANEAGTLYNLLSHII
YNGLNMNKIESRPIEGNVEGKRWNFRFFVDFTGNIDDPRVMNALRGIEEEAESIKLLGNY
>Mature_380_residues
MLDLNEIRNNIDKIDSQLVELFEERMKLTTEVAEYKIETGKKVLDPAREKAKLESVKKLVKNPDNVHAIDDLFAQIMANS
RKNQYMLLEKMGQTLREPYEAIDEINKKDCKVVYQGVPGAYSYAAMINFFGKDVDNFNVPTWRECMEAVKQGKADYAVLP
IENSNAGIVADVYDLLQEYNNYIIAETYVKIEHLLLGLPGTDLENVTAVYSHPQGLMQCDRFLDTHKDWQRISQANTALA
AKMIFQEHNKTHVAIASKEAAELYGLDILKSGITDQEGNTTRFVIVTNTRKFVKNAQKMSIVFETANEAGTLYNLLSHII
YNGLNMNKIESRPIEGNVEGKRWNFRFFVDFTGNIDDPRVMNALRGIEEEAESIKLLGNY

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=380, Percent_Identity=31.3157894736842, Blast_Score=191, Evalue=6e-50,
Organism=Saccharomyces cerevisiae, GI6324013, Length=300, Percent_Identity=26.6666666666667, Blast_Score=93, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 43297; Mature: 43297

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00857 PREPHENATE_DEHYDR_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLNEIRNNIDKIDSQLVELFEERMKLTTEVAEYKIETGKKVLDPAREKAKLESVKKLV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
KNPDNVHAIDDLFAQIMANSRKNQYMLLEKMGQTLREPYEAIDEINKKDCKVVYQGVPGA
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCH
YSYAAMINFFGKDVDNFNVPTWRECMEAVKQGKADYAVLPIENSNAGIVADVYDLLQEYN
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHC
NYIIAETYVKIEHLLLGLPGTDLENVTAVYSHPQGLMQCDRFLDTHKDWQRISQANTALA
CEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKMIFQEHNKTHVAIASKEAAELYGLDILKSGITDQEGNTTRFVIVTNTRKFVKNAQKMS
HHHHHHHCCCCEEEEECHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHHHCHHHHE
IVFETANEAGTLYNLLSHIIYNGLNMNKIESRPIEGNVEGKRWNFRFFVDFTGNIDDPRV
EEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCHHH
MNALRGIEEEAESIKLLGNY
HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLDLNEIRNNIDKIDSQLVELFEERMKLTTEVAEYKIETGKKVLDPAREKAKLESVKKLV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
KNPDNVHAIDDLFAQIMANSRKNQYMLLEKMGQTLREPYEAIDEINKKDCKVVYQGVPGA
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCH
YSYAAMINFFGKDVDNFNVPTWRECMEAVKQGKADYAVLPIENSNAGIVADVYDLLQEYN
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHC
NYIIAETYVKIEHLLLGLPGTDLENVTAVYSHPQGLMQCDRFLDTHKDWQRISQANTALA
CEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKMIFQEHNKTHVAIASKEAAELYGLDILKSGITDQEGNTTRFVIVTNTRKFVKNAQKMS
HHHHHHHCCCCEEEEECHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHHHCHHHHE
IVFETANEAGTLYNLLSHIIYNGLNMNKIESRPIEGNVEGKRWNFRFFVDFTGNIDDPRV
EEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCHHH
MNALRGIEEEAESIKLLGNY
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1512561; 1444388 [H]