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The map label for this gene is 238922190

Identifier: 238922190

GI number: 238922190

Start: 386448

End: 387674

Strand: Reverse

Name: 238922190

Synonym: EUBELI_20425

Alternate gene names: NA

Gene position: 387674-386448 (Counterclockwise)

Preceding gene: 238922191

Following gene: 238922189

Centisome position: 61.86

GC content: 36.27

Gene sequence:

>1227_bases
GTGAATTTAGAAGAAGCAAAGCTTAAGCTTTCAAAGTACGGTCAGGAACAGATATTAAGATATTATGATGAATTATCAGA
TGATGAGAAGGTAGCACTTCTTGAACAGATTGATAAGACTGATATGGAAGTTTTATCGGCAATTGAACATAAGTCTGAGC
TTGTTAAGAAAGGTGAAATTACACCTCTTGATGCAATGGAACTTGATGAGATAGAAGCAGACTATGATACATTTAAGAAT
ACAGGTGTAGAAGCAATTAAGGCCGGAAAGGTTGGAGCAATTCTTCTTGCAGGTGGAATGGGAACAAGACTTGGTTCTGA
TAATCCTAAAGGAATGTATAATGTAGGTGTTAACAAGGAACTTTATATATTCGAGTGCCTTATTAATAATCTTATGGATG
TTGTTAAGGAAACAGGAACTTATATACATTTATTTGTTATGACAAGTGAGAAGAATAATGATGCTACAGTTTCTTTCTTT
GAAGAAAAGGATTTCTTTGGATATAAGAGTGAATATGTACATTTCTTCAAGCAGGAGATGGCAGCAGCTACTGATTATGA
AGGTAAGATATACCTTGAAGAAAAGGGAAGAATGGCTACATCACCTAATGGTAATGGTGGATGGTATATCTCTTTAAAGA
AGGCTGGATTAACAGAGGTTCTTGAGAAGAACGGAATTGAGTGGCTGAATGTATTCGCTGTTGACAATGTTCTTCAGAGA
ATTGCAGACCCTGTATTTATCGGTGCTACAATTGAAAAGCACTGTGCAGTTGGTTCTAAGGTTGTAAGAAAAGCAGCTCC
TGATGAGAAGGTAGGTGTTATGTGCCTTGAAGATGGCAAGCCTTCTATTGTTGAGTATTATGAACTTACTAAAGAGATGA
TGGATGCTAAGAATGCAAAAGGCGACCCTGCATATAATTTTGGAGTTATTCTTAACTATCTGTTCAGGGTTTCTGATCTT
GAAAGAATTGTTGGAAAGAATCTTCCTTTACATATTGTTGAGAAGAAGATTCCATATATTGATGCGAATGGTGATCTTGT
TAAGCCGGAAAAGCCTAATGGATATAAGTTTGAGGGTCTTGTTCTTGATATGATTCATGAGCTTGACAGTTGCCTGCCAT
TTGAGGTAGTAAGAGAAAAGGAATTTGCACCAATTAAGAATGCAACAGGTGTTGATTCAGTTGAATCAGCAAGAGAACTT
CTTAAGAAGAATGGTGTTGCAATTTAA

Upstream 100 bases:

>100_bases
GAGGAAGCTGAGTCAATTAAGTTGCTTGGAAACTATTAATGTGTTAGAATTATGAAGATGTCGTCAGACAATAAGTTATT
AGATAAGTGAGGAAATTAGA

Downstream 100 bases:

>100_bases
CATATTTTGTTGTATGTTATTAATAAGTGCTGTACAACTGGCGGAAGATGCCTTATGGGCATTGTGGGATAACCCACAGG
GAGTACAGTTTATATTAAAA

Product: UDP-N-acetylglucosamine pyrophosphorylase

Products: diphosphate; UDP-N-acetyl-D-glucosamine

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MNLEEAKLKLSKYGQEQILRYYDELSDDEKVALLEQIDKTDMEVLSAIEHKSELVKKGEITPLDAMELDEIEADYDTFKN
TGVEAIKAGKVGAILLAGGMGTRLGSDNPKGMYNVGVNKELYIFECLINNLMDVVKETGTYIHLFVMTSEKNNDATVSFF
EEKDFFGYKSEYVHFFKQEMAAATDYEGKIYLEEKGRMATSPNGNGGWYISLKKAGLTEVLEKNGIEWLNVFAVDNVLQR
IADPVFIGATIEKHCAVGSKVVRKAAPDEKVGVMCLEDGKPSIVEYYELTKEMMDAKNAKGDPAYNFGVILNYLFRVSDL
ERIVGKNLPLHIVEKKIPYIDANGDLVKPEKPNGYKFEGLVLDMIHELDSCLPFEVVREKEFAPIKNATGVDSVESAREL
LKKNGVAI

Sequences:

>Translated_408_residues
MNLEEAKLKLSKYGQEQILRYYDELSDDEKVALLEQIDKTDMEVLSAIEHKSELVKKGEITPLDAMELDEIEADYDTFKN
TGVEAIKAGKVGAILLAGGMGTRLGSDNPKGMYNVGVNKELYIFECLINNLMDVVKETGTYIHLFVMTSEKNNDATVSFF
EEKDFFGYKSEYVHFFKQEMAAATDYEGKIYLEEKGRMATSPNGNGGWYISLKKAGLTEVLEKNGIEWLNVFAVDNVLQR
IADPVFIGATIEKHCAVGSKVVRKAAPDEKVGVMCLEDGKPSIVEYYELTKEMMDAKNAKGDPAYNFGVILNYLFRVSDL
ERIVGKNLPLHIVEKKIPYIDANGDLVKPEKPNGYKFEGLVLDMIHELDSCLPFEVVREKEFAPIKNATGVDSVESAREL
LKKNGVAI
>Mature_408_residues
MNLEEAKLKLSKYGQEQILRYYDELSDDEKVALLEQIDKTDMEVLSAIEHKSELVKKGEITPLDAMELDEIEADYDTFKN
TGVEAIKAGKVGAILLAGGMGTRLGSDNPKGMYNVGVNKELYIFECLINNLMDVVKETGTYIHLFVMTSEKNNDATVSFF
EEKDFFGYKSEYVHFFKQEMAAATDYEGKIYLEEKGRMATSPNGNGGWYISLKKAGLTEVLEKNGIEWLNVFAVDNVLQR
IADPVFIGATIEKHCAVGSKVVRKAAPDEKVGVMCLEDGKPSIVEYYELTKEMMDAKNAKGDPAYNFGVILNYLFRVSDL
ERIVGKNLPLHIVEKKIPYIDANGDLVKPEKPNGYKFEGLVLDMIHELDSCLPFEVVREKEFAPIKNATGVDSVESAREL
LKKNGVAI

Specific function: Unknown

COG id: COG4284

COG function: function code G; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 1 family [H]

Homologues:

Organism=Homo sapiens, GI156627575, Length=429, Percent_Identity=36.8298368298368, Blast_Score=272, Evalue=4e-73,
Organism=Homo sapiens, GI187936958, Length=423, Percent_Identity=36.6430260047281, Blast_Score=248, Evalue=6e-66,
Organism=Caenorhabditis elegans, GI17552518, Length=407, Percent_Identity=35.1351351351351, Blast_Score=207, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI193206427, Length=318, Percent_Identity=35.5345911949685, Blast_Score=171, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6320100, Length=406, Percent_Identity=34.9753694581281, Blast_Score=223, Evalue=4e-59,
Organism=Drosophila melanogaster, GI19920822, Length=421, Percent_Identity=33.4916864608076, Blast_Score=258, Evalue=4e-69,
Organism=Drosophila melanogaster, GI24582229, Length=421, Percent_Identity=33.4916864608076, Blast_Score=258, Evalue=6e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002618 [H]

Pfam domain/function: PF01704 UDPGP [H]

EC number: 2.7.7.23

Molecular weight: Translated: 45668; Mature: 45668

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLEEAKLKLSKYGQEQILRYYDELSDDEKVALLEQIDKTDMEVLSAIEHKSELVKKGEI
CCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCC
TPLDAMELDEIEADYDTFKNTGVEAIKAGKVGAILLAGGMGTRLGSDNPKGMYNVGVNKE
CCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEECCCCCC
LYIFECLINNLMDVVKETGTYIHLFVMTSEKNNDATVSFFEEKDFFGYKSEYVHFFKQEM
HHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
AAATDYEGKIYLEEKGRMATSPNGNGGWYISLKKAGLTEVLEKNGIEWLNVFAVDNVLQR
HHCCCCCCEEEEECCCCEECCCCCCCCEEEEEECCCHHHHHHHCCCCEEHHHHHHHHHHH
IADPVFIGATIEKHCAVGSKVVRKAAPDEKVGVMCLEDGKPSIVEYYELTKEMMDAKNAK
HCCCEEEECHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCC
GDPAYNFGVILNYLFRVSDLERIVGKNLPLHIVEKKIPYIDANGDLVKPEKPNGYKFEGL
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEECCCCCEECCCCCCCEEEHHH
VLDMIHELDSCLPFEVVREKEFAPIKNATGVDSVESARELLKKNGVAI
HHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNLEEAKLKLSKYGQEQILRYYDELSDDEKVALLEQIDKTDMEVLSAIEHKSELVKKGEI
CCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCC
TPLDAMELDEIEADYDTFKNTGVEAIKAGKVGAILLAGGMGTRLGSDNPKGMYNVGVNKE
CCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEECCCCCC
LYIFECLINNLMDVVKETGTYIHLFVMTSEKNNDATVSFFEEKDFFGYKSEYVHFFKQEM
HHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
AAATDYEGKIYLEEKGRMATSPNGNGGWYISLKKAGLTEVLEKNGIEWLNVFAVDNVLQR
HHCCCCCCEEEEECCCCEECCCCCCCCEEEEEECCCHHHHHHHCCCCEEHHHHHHHHHHH
IADPVFIGATIEKHCAVGSKVVRKAAPDEKVGVMCLEDGKPSIVEYYELTKEMMDAKNAK
HCCCEEEECHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCC
GDPAYNFGVILNYLFRVSDLERIVGKNLPLHIVEKKIPYIDANGDLVKPEKPNGYKFEGL
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEECCCCCEECCCCCCCEEEHHH
VLDMIHELDSCLPFEVVREKEFAPIKNATGVDSVESARELLKKNGVAI
HHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UTP; N-acetyl-alpha-D-glucosamine 1-phosphate

Specific reaction: UTP + N-acetyl-alpha-D-glucosamine 1-phosphate = diphosphate + UDP-N-acetyl-D-glucosamine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA