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The map label for this gene is nfuA

Identifier: 238921502

GI number: 238921502

Start: 3540823

End: 3541398

Strand: Direct

Name: nfuA

Synonym: NT01EI_3654

Alternate gene names: 238921502

Gene position: 3540823-3541398 (Clockwise)

Preceding gene: 238921501

Following gene: 238921506

Centisome position: 92.88

GC content: 59.38

Gene sequence:

>576_bases
ATGATCCGTATTACCGAAGCAGCGCAAGAGCACTTTGCCAAATTGCTGGCAAACCAGGAGCCGGGTACCCAGATCCGCGT
TTTTGTCATTAACCCCGGTACGCCCAATGCGGAGTGCGGCGTCTCCTACTGCCCGCCGGACGCCGTAGAAGCCAATGACC
GTAAGCTGGACTTTGAGCAGCTGAGCGCCTATGTCGACGAAATCAGCGCCCCGTTCCTGGACGATGCCGAGATCGACTTT
GTCACCGATCAGCTCGGCTCGCAGCTGACCCTAAAAGCCCCCAACGCCAAGATGCGTAAAGTCGCCGACGATGCGCCACT
GATCGAGCGCGTGGAGTATATTCTGCAGTCGCAGATTAACCCCCAGCTGGCGGGCCACGGCGGTCGCGTCTCGCTGATGG
AGATCACCGATGAAGGCTACGCTATTCTGCAGTTCGGCGGCGGCTGCAACGGCTGCTCCATGGTGGACTACACCCTGAAA
GAGGGGATCGAGAAAGAGCTGCTGCAACGCTTCCCAGAGCTGAAGGGCGTACGCGATCTGACCGAGCACCAGCGCGGCGA
CCACTCTTACTACTGA

Upstream 100 bases:

>100_bases
GTGATGTCGGTAGAGACGATCTGTCTGTGCCGCACCTTGTGAGCATTTTACGATCGGCGTATTATAACCGACCGGAGTAG
TCAACTATTGAGCAGATGCC

Downstream 100 bases:

>100_bases
TCTGTGATAATCCGTTGATATGATGACGTATCAACGGATACCCTTTAAGCCAATACCTTGCAGATATAGGCAACGTCCGG
TCATTGTCCGGGGCATTATC

Product: DNA uptake protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MIRITEAAQEHFAKLLANQEPGTQIRVFVINPGTPNAECGVSYCPPDAVEANDRKLDFEQLSAYVDEISAPFLDDAEIDF
VTDQLGSQLTLKAPNAKMRKVADDAPLIERVEYILQSQINPQLAGHGGRVSLMEITDEGYAILQFGGGCNGCSMVDYTLK
EGIEKELLQRFPELKGVRDLTEHQRGDHSYY

Sequences:

>Translated_191_residues
MIRITEAAQEHFAKLLANQEPGTQIRVFVINPGTPNAECGVSYCPPDAVEANDRKLDFEQLSAYVDEISAPFLDDAEIDF
VTDQLGSQLTLKAPNAKMRKVADDAPLIERVEYILQSQINPQLAGHGGRVSLMEITDEGYAILQFGGGCNGCSMVDYTLK
EGIEKELLQRFPELKGVRDLTEHQRGDHSYY
>Mature_191_residues
MIRITEAAQEHFAKLLANQEPGTQIRVFVINPGTPNAECGVSYCPPDAVEANDRKLDFEQLSAYVDEISAPFLDDAEIDF
VTDQLGSQLTLKAPNAKMRKVADDAPLIERVEYILQSQINPQLAGHGGRVSLMEITDEGYAILQFGGGCNGCSMVDYTLK
EGIEKELLQRFPELKGVRDLTEHQRGDHSYY

Specific function: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins

COG id: COG0694

COG function: function code O; Thioredoxin-like proteins and domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nfuA family

Homologues:

Organism=Escherichia coli, GI1789819, Length=191, Percent_Identity=87.9581151832461, Blast_Score=355, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NFUA_EDWI9 (C5BGT5)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002935017.1
- ProteinModelPortal:   C5BGT5
- GeneID:   7962162
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_3654
- OMA:   CQGCSAV
- ProtClustDB:   PRK11190
- HAMAP:   MF_01637
- InterPro:   IPR017726
- InterPro:   IPR000361
- InterPro:   IPR001075
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- ProDom:   PD002830
- TIGRFAMs:   TIGR03341

Pfam domain/function: PF01521 Fe-S_biosyn; PF01106 NifU; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 21205; Mature: 21205

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRITEAAQEHFAKLLANQEPGTQIRVFVINPGTPNAECGVSYCPPDAVEANDRKLDFEQ
CEEEHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
LSAYVDEISAPFLDDAEIDFVTDQLGSQLTLKAPNAKMRKVADDAPLIERVEYILQSQIN
HHHHHHHHCCCCCCCCCHHHHHHHCCCEEEEECCCHHHHHHCCCCHHHHHHHHHHHHCCC
PQLAGHGGRVSLMEITDEGYAILQFGGGCNGCSMVDYTLKEGIEKELLQRFPELKGVRDL
CCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCHHHCCHHHH
TEHQRGDHSYY
HHHCCCCCCCC
>Mature Secondary Structure
MIRITEAAQEHFAKLLANQEPGTQIRVFVINPGTPNAECGVSYCPPDAVEANDRKLDFEQ
CEEEHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
LSAYVDEISAPFLDDAEIDFVTDQLGSQLTLKAPNAKMRKVADDAPLIERVEYILQSQIN
HHHHHHHHCCCCCCCCCHHHHHHHCCCEEEEECCCHHHHHHCCCCHHHHHHHHHHHHCCC
PQLAGHGGRVSLMEITDEGYAILQFGGGCNGCSMVDYTLKEGIEKELLQRFPELKGVRDL
CCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCHHHCCHHHH
TEHQRGDHSYY
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA