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The map label for this gene is surE

Identifier: 238921114

GI number: 238921114

Start: 3131368

End: 3132132

Strand: Reverse

Name: surE

Synonym: NT01EI_3253

Alternate gene names: 238921114

Gene position: 3132132-3131368 (Counterclockwise)

Preceding gene: 238921115

Following gene: 238921113

Centisome position: 82.16

GC content: 65.36

Gene sequence:

>765_bases
ATGCGGATCTTGCTGAGTAATGATGATGGTGTAACGGCTCCCGGTATTCAGACGCTGGCAGCGGCGCTACGAGAGTTTGC
CCAGGTGCAGGTCGTCGCTCCGAACCGCAATCGCAGCGGGTCGTCCAATGCCCTGACGCTGGAGTCACCGCTGCGCAGCG
AAACCTTGGCCAACGGCGACATCAGCGTGATCGACGGTACGCCGACCGACTGCGTCTATCTGGGGGTCAATGCGTTGATG
CGCCCGCGCCCGGATATCGTGATCGCCGGTATCAACGCTGGCCCTAACCTGGGAGATGACGTGATCTACTCCGGCACGGT
GGCGGCGGCGATGGAGGGGCGCCATCTGGGCTTTCCTGCGCTGGCGGTATCTCTGGACGGTGAGCGTCACTATGACACGG
CGGCGGCGGTCACCTGCCGACTGTTGCGTATGCTGTCTGATGCACCGCTGCGCAGTGGGCGCATTCTGAATGTGAATGTG
CCGGACGTCCCACTGACGGCGATCCGAGGCTGGCGCGTAACCCGCTGCGGCAGCCGTCATCCGGCGCAGACGGTGATCCA
TCAGCAGGATCCGCGCGGTAAGCCGCTGATGTGGATCGGTCCGCCGGGGGCCAAGCAGGACGCCGGTGAAGAGACCGATT
TCGCCGCCGTGGCGGCGGGCTATATCTCCGTGACGCCACTGCAGGTGGATCTGACCGCCCACGGTGCGCGTGGCCGCCTG
GCGGAGTGGCTGGGCCGGGTGGATAAGGGCGGTGCGGCATGGTAG

Upstream 100 bases:

>100_bases
AGCTGGTGGGATGACGCCACCGTCGAGCTGACCTTCGATCTGCCCGCCGGTAGTTTCGCCACCAGCGTAGTGCGTGAACT
GTTCTGTCAGGAAAACTCCG

Downstream 100 bases:

>100_bases
ATGTTGATCGCCGGGTTCTGCTGCTGATCCAGCAGCTGATGCGTCAGGGGATCCGCGATGAGGCGGTGCTGAAAGCCATT
GCTTCTGTGCCGCGCGAGCG

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: 5'/3'-nucleotidase; Nucleoside monophosphate phosphohydrolase; Exopolyphosphatase

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MRILLSNDDGVTAPGIQTLAAALREFAQVQVVAPNRNRSGSSNALTLESPLRSETLANGDISVIDGTPTDCVYLGVNALM
RPRPDIVIAGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGERHYDTAAAVTCRLLRMLSDAPLRSGRILNVNV
PDVPLTAIRGWRVTRCGSRHPAQTVIHQQDPRGKPLMWIGPPGAKQDAGEETDFAAVAAGYISVTPLQVDLTAHGARGRL
AEWLGRVDKGGAAW

Sequences:

>Translated_254_residues
MRILLSNDDGVTAPGIQTLAAALREFAQVQVVAPNRNRSGSSNALTLESPLRSETLANGDISVIDGTPTDCVYLGVNALM
RPRPDIVIAGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGERHYDTAAAVTCRLLRMLSDAPLRSGRILNVNV
PDVPLTAIRGWRVTRCGSRHPAQTVIHQQDPRGKPLMWIGPPGAKQDAGEETDFAAVAAGYISVTPLQVDLTAHGARGRL
AEWLGRVDKGGAAW
>Mature_254_residues
MRILLSNDDGVTAPGIQTLAAALREFAQVQVVAPNRNRSGSSNALTLESPLRSETLANGDISVIDGTPTDCVYLGVNALM
RPRPDIVIAGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGERHYDTAAAVTCRLLRMLSDAPLRSGRILNVNV
PDVPLTAIRGWRVTRCGSRHPAQTVIHQQDPRGKPLMWIGPPGAKQDAGEETDFAAVAAGYISVTPLQVDLTAHGARGRL
AEWLGRVDKGGAAW

Specific function: Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'- monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase acti

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=250, Percent_Identity=76.8, Blast_Score=389, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_EDWI9 (C5BGI8)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002934629.1
- ProteinModelPortal:   C5BGI8
- GeneID:   7961086
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_3253
- OMA:   NGFYYVN
- ProtClustDB:   PRK00346
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5; =3.1.3.6; =3.6.1.11

Molecular weight: Translated: 26839; Mature: 26839

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLSNDDGVTAPGIQTLAAALREFAQVQVVAPNRNRSGSSNALTLESPLRSETLANGD
CEEEEECCCCCCCCCHHHHHHHHHHHHEEEEECCCCCCCCCCCEEEECCCCCHHHCCCCC
ISVIDGTPTDCVYLGVNALMRPRPDIVIAGINAGPNLGDDVIYSGTVAAAMEGRHLGFPA
EEEECCCCCCEEEECHHHHCCCCCCEEEEECCCCCCCCCCEEECCEEEEEECCCCCCCCE
LAVSLDGERHYDTAAAVTCRLLRMLSDAPLRSGRILNVNVPDVPLTAIRGWRVTRCGSRH
EEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHCCEEEEECCCCC
PAQTVIHQQDPRGKPLMWIGPPGAKQDAGEETDFAAVAAGYISVTPLQVDLTAHGARGRL
CHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCHHHEEECEEEEEEEEEEEECCCCCCHH
AEWLGRVDKGGAAW
HHHHCCCCCCCCCC
>Mature Secondary Structure
MRILLSNDDGVTAPGIQTLAAALREFAQVQVVAPNRNRSGSSNALTLESPLRSETLANGD
CEEEEECCCCCCCCCHHHHHHHHHHHHEEEEECCCCCCCCCCCEEEECCCCCHHHCCCCC
ISVIDGTPTDCVYLGVNALMRPRPDIVIAGINAGPNLGDDVIYSGTVAAAMEGRHLGFPA
EEEECCCCCCEEEECHHHHCCCCCCEEEEECCCCCCCCCCEEECCEEEEEECCCCCCCCE
LAVSLDGERHYDTAAAVTCRLLRMLSDAPLRSGRILNVNVPDVPLTAIRGWRVTRCGSRH
EEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHCCEEEEECCCCC
PAQTVIHQQDPRGKPLMWIGPPGAKQDAGEETDFAAVAAGYISVTPLQVDLTAHGARGRL
CHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCHHHEEECEEEEEEEEEEEECCCCCCHH
AEWLGRVDKGGAAW
HHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA