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The map label for this gene is ccmE [H]

Identifier: 238920653

GI number: 238920653

Start: 2664325

End: 2664852

Strand: Reverse

Name: ccmE [H]

Synonym: NT01EI_2765

Alternate gene names: 238920653

Gene position: 2664852-2664325 (Counterclockwise)

Preceding gene: 238920654

Following gene: 238920652

Centisome position: 69.9

GC content: 58.33

Gene sequence:

>528_bases
ATGATGAATTCACGACGTAAACATCGTTTATACCTGGCCGTGGGTGTCTTGCTGGGGCTGGCCGTCACGGTATCGCTGGT
GCTGTATGCCCTGCGTGCCAACATCGACCTGTTCTACACCCCCGGTGAAATCATCATGGGGAAAGGGGCACAGCATGAGA
AGCCGGAGGTGGGCCAGCGCCTGCGTATCGGCGGCATGGTGATGCCCGGTTCGGTGCAGCGCGACGCTGATAGCCTGAAG
GTGAGCTTCAAGCTGTATGACGCCCGTGGAGTGGTCGGAGTGACCTACAACGGCATTCTGCCCGACCTGTTCCGTGAAGG
GCAGGGGGTGGTCGCTCAGGGGGTGTTGGCGCCGGGCAACGTGATTCAGGCCAAAGAGGTGCTGGCCAAACATGATGAAA
AATATACCCCGCCGGAGATTGAGGAAGCGATGAAAGAGAATCATTCGCCGGAGATCGAGGCGGCGGTGAAAGAGAACTCT
CATCAGTCCGTATCGGGCGCAGAGCAACGGGACGGTAACCCATTATGA

Upstream 100 bases:

>100_bases
GCGCGTTGTTTGGCGAGATCCGCCGCCATCAGGCGCGGGAACAACGGATACGCCAGGCGCAGCAGGCTATGGGTGACAAT
AACCGGGAGAGTGACCTCAT

Downstream 100 bases:

>100_bases
TCCCAGAGATCGGTAACTTTTTACTGTCGTTGGCGCTGGCGCTTTCCGTGCTGCTCAGCGTCTACCCCTGCTGGGGCGCG
GCGCGCGGCGATCGGCGCAT

Product: hypothetical protein

Products: NA

Alternate protein names: Cytochrome c maturation protein E; Heme chaperone CcmE [H]

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MMNSRRKHRLYLAVGVLLGLAVTVSLVLYALRANIDLFYTPGEIIMGKGAQHEKPEVGQRLRIGGMVMPGSVQRDADSLK
VSFKLYDARGVVGVTYNGILPDLFREGQGVVAQGVLAPGNVIQAKEVLAKHDEKYTPPEIEEAMKENHSPEIEAAVKENS
HQSVSGAEQRDGNPL

Sequences:

>Translated_175_residues
MMNSRRKHRLYLAVGVLLGLAVTVSLVLYALRANIDLFYTPGEIIMGKGAQHEKPEVGQRLRIGGMVMPGSVQRDADSLK
VSFKLYDARGVVGVTYNGILPDLFREGQGVVAQGVLAPGNVIQAKEVLAKHDEKYTPPEIEEAMKENHSPEIEAAVKENS
HQSVSGAEQRDGNPL
>Mature_175_residues
MMNSRRKHRLYLAVGVLLGLAVTVSLVLYALRANIDLFYTPGEIIMGKGAQHEKPEVGQRLRIGGMVMPGSVQRDADSLK
VSFKLYDARGVVGVTYNGILPDLFREGQGVVAQGVLAPGNVIQAKEVLAKHDEKYTPPEIEEAMKENHSPEIEAAVKENS
HQSVSGAEQRDGNPL

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH [H]

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family [H]

Homologues:

Organism=Escherichia coli, GI1788525, Length=147, Percent_Identity=72.108843537415, Blast_Score=221, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004329
- InterPro:   IPR012340 [H]

Pfam domain/function: PF03100 CcmE [H]

EC number: NA

Molecular weight: Translated: 19060; Mature: 19060

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNSRRKHRLYLAVGVLLGLAVTVSLVLYALRANIDLFYTPGEIIMGKGAQHEKPEVGQR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEECCCCCCCCCCCCCE
LRIGGMVMPGSVQRDADSLKVSFKLYDARGVVGVTYNGILPDLFREGQGVVAQGVLAPGN
EEECCEECCCCCCCCCCCEEEEEEEECCCCEEEEEECCCCHHHHHCCCCCEEECEECCCC
VIQAKEVLAKHDEKYTPPEIEEAMKENHSPEIEAAVKENSHQSVSGAEQRDGNPL
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MMNSRRKHRLYLAVGVLLGLAVTVSLVLYALRANIDLFYTPGEIIMGKGAQHEKPEVGQR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEECCCCCCCCCCCCCE
LRIGGMVMPGSVQRDADSLKVSFKLYDARGVVGVTYNGILPDLFREGQGVVAQGVLAPGN
EEECCEECCCCCCCCCCCEEEEEEEECCCCEEEEEECCCCHHHHHCCCCCEEECEECCCC
VIQAKEVLAKHDEKYTPPEIEEAMKENHSPEIEAAVKENSHQSVSGAEQRDGNPL
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA