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The map label for this gene is nuoN [H]

Identifier: 238920555

GI number: 238920555

Start: 2560797

End: 2562254

Strand: Reverse

Name: nuoN [H]

Synonym: NT01EI_2667

Alternate gene names: 238920555

Gene position: 2562254-2560797 (Counterclockwise)

Preceding gene: 238920556

Following gene: 238920548

Centisome position: 67.21

GC content: 61.52

Gene sequence:

>1458_bases
ATGACAATAACTCCTCAAAATCTGATCGCACTGCTACCGCTGTTGATCGTCGGATTGACGGTGGTGGTTGTGATGCTGTG
CATTGCGTGGCGACGCAACCACTTCGTCAACGCGACGGTGACCGTGATTGGCCTGAACGCAGCGTTGCTGTCGCTGTTTC
TGGTGGCCGCCGCGGTGCCCAGCGACATTACTCCGCTGGTGCATGTGGACGGCTTCTCGATGCTCTACACCGCGCTGGTG
CTGCTTTCCGCGCTGGCGACCTGCACCTTTGCCTATCCGTGGCTGCAGGGCTATCCGGATAACCGCGATGAGTTTTACCT
GCTGGTGCTGATCGCCACACTGGGCGGGATCCTGCTGGCCTGCGCCAACCATCTGGCGGCGCTGTTTTTGGGGGTAGAAC
TTATCTCCCTGCCGCTATTCGGTCTGGTGGGTTACGCCTATCGTCAGAAGCGCTCGCTGGAGGCGGCGATAAAGTACGCT
ATCCTTTCGGCCGCTGCGTCCGCCTTCCTGCTGTTCGGCATGGCGCTGCTGTACGCGCAGTCCGGTGACCTCTCTTTCGC
CGGTCTGGGCTATGCGCTGGGCGGCCGTATGCTGGCCCAGCCACTGGTGCTGGCAGGGCTTGGCATGATGCTGGTGGGCT
TCGGCTTTAAACTGTCTCTGGTGCCGTTCCAGCTGTGGACGCCGGATGTCTACCAGGGGGCGCCGGCGCCGGTGTCGACC
TTTCTGGCGACTGCCAGCAAGATCGCCATCTTTGCGGTGCTGCTGCGTCTGTTTGTTCTGCTGCCGGCGACCGACAGCGA
GGCGGTACGCGTGGTGCTGGGTGTTATCGCTTTCTGCTCCATCCTGTTCGGTAACCTGATGGCGGTAACCCAGAGCAACA
TTAAACGTCTGCTGGGCTACTCCTCTATCGCCCATCTGGGCTATCTGCTGGTAGCGCTGATCGCCGTGCAGAGCGAGGGC
ATTGCGATCGAGACTGCCGGGGTCTATCTGGCCGGCTATCTGTTTGCCAGCCTGTCGGCTTTCGGCATCGTCAGCCTGAT
GTCCAGCCCTTACAGCGGGCCAGACGCCGAGTCGCTTTACTCCTATCGCGGCCTGTTCTGGCATAAGCCGATTCTGTCGG
CGGTGATGACCGTATCCATGCTCTCCCTGGCCGGTATCCCGATGACTCTGGGCTTTATCGGTAAGCTGTTTGTGGTGATG
GCGGGCGTCAGCGCCGGGTTGTGGTGGCTGGTGGGGGCGGTGGTGGTCGGCAGTGCTATCGGCCTCTATTACTACCTACG
CGTTGCCGTCAGTATGTATCTGCGCGCGCCGCAGACGCTGATCCGCGATACCCCGAACAACTGGGCGCTCACCGCCGGTG
GTGTGGTGGTACTGCTCTCAGGCGTGTTGGTGGTGTTGACGGGGCTCTTCCCGCAGACGCTGATTTCGCTGGTGCAGCTG
GCGCAGCCGCTGCCCTGA

Upstream 100 bases:

>100_bases
CTTCCCGCAGCCGGTGCTGGACACCTCCAGCGCGGCGATGGGCAATATTCAGCATTGGTTCGCTTCTGCTTCAACTTTAA
CCACAAGGCCGTAAATCGCC

Downstream 100 bases:

>100_bases
TGGGAGTGACACGATGAGATAATGCCGGGCCATGGGCCCGGCATTTTTTTCATCTAGCGGGTAATAGAAAAGAAGAGATC
GCAGGCAAAGGCGCTGATGA

Product: NADH-quinone oxidoreductase subunit n

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MTITPQNLIALLPLLIVGLTVVVVMLCIAWRRNHFVNATVTVIGLNAALLSLFLVAAAVPSDITPLVHVDGFSMLYTALV
LLSALATCTFAYPWLQGYPDNRDEFYLLVLIATLGGILLACANHLAALFLGVELISLPLFGLVGYAYRQKRSLEAAIKYA
ILSAAASAFLLFGMALLYAQSGDLSFAGLGYALGGRMLAQPLVLAGLGMMLVGFGFKLSLVPFQLWTPDVYQGAPAPVST
FLATASKIAIFAVLLRLFVLLPATDSEAVRVVLGVIAFCSILFGNLMAVTQSNIKRLLGYSSIAHLGYLLVALIAVQSEG
IAIETAGVYLAGYLFASLSAFGIVSLMSSPYSGPDAESLYSYRGLFWHKPILSAVMTVSMLSLAGIPMTLGFIGKLFVVM
AGVSAGLWWLVGAVVVGSAIGLYYYLRVAVSMYLRAPQTLIRDTPNNWALTAGGVVVLLSGVLVVLTGLFPQTLISLVQL
AQPLP

Sequences:

>Translated_485_residues
MTITPQNLIALLPLLIVGLTVVVVMLCIAWRRNHFVNATVTVIGLNAALLSLFLVAAAVPSDITPLVHVDGFSMLYTALV
LLSALATCTFAYPWLQGYPDNRDEFYLLVLIATLGGILLACANHLAALFLGVELISLPLFGLVGYAYRQKRSLEAAIKYA
ILSAAASAFLLFGMALLYAQSGDLSFAGLGYALGGRMLAQPLVLAGLGMMLVGFGFKLSLVPFQLWTPDVYQGAPAPVST
FLATASKIAIFAVLLRLFVLLPATDSEAVRVVLGVIAFCSILFGNLMAVTQSNIKRLLGYSSIAHLGYLLVALIAVQSEG
IAIETAGVYLAGYLFASLSAFGIVSLMSSPYSGPDAESLYSYRGLFWHKPILSAVMTVSMLSLAGIPMTLGFIGKLFVVM
AGVSAGLWWLVGAVVVGSAIGLYYYLRVAVSMYLRAPQTLIRDTPNNWALTAGGVVVLLSGVLVVLTGLFPQTLISLVQL
AQPLP
>Mature_484_residues
TITPQNLIALLPLLIVGLTVVVVMLCIAWRRNHFVNATVTVIGLNAALLSLFLVAAAVPSDITPLVHVDGFSMLYTALVL
LSALATCTFAYPWLQGYPDNRDEFYLLVLIATLGGILLACANHLAALFLGVELISLPLFGLVGYAYRQKRSLEAAIKYAI
LSAAASAFLLFGMALLYAQSGDLSFAGLGYALGGRMLAQPLVLAGLGMMLVGFGFKLSLVPFQLWTPDVYQGAPAPVSTF
LATASKIAIFAVLLRLFVLLPATDSEAVRVVLGVIAFCSILFGNLMAVTQSNIKRLLGYSSIAHLGYLLVALIAVQSEGI
AIETAGVYLAGYLFASLSAFGIVSLMSSPYSGPDAESLYSYRGLFWHKPILSAVMTVSMLSLAGIPMTLGFIGKLFVVMA
GVSAGLWWLVGAVVVGSAIGLYYYLRVAVSMYLRAPQTLIRDTPNNWALTAGGVVVLLSGVLVVLTGLFPQTLISLVQLA
QPLP

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=397, Percent_Identity=23.4256926952141, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI145693160, Length=484, Percent_Identity=77.0661157024793, Blast_Score=743, Evalue=0.0,
Organism=Escherichia coli, GI1788831, Length=311, Percent_Identity=27.3311897106109, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1788829, Length=319, Percent_Identity=26.6457680250784, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788614, Length=266, Percent_Identity=27.4436090225564, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1788613, Length=388, Percent_Identity=26.8041237113402, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 51441; Mature: 51310

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITPQNLIALLPLLIVGLTVVVVMLCIAWRRNHFVNATVTVIGLNAALLSLFLVAAAVP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHHCC
SDITPLVHVDGFSMLYTALVLLSALATCTFAYPWLQGYPDNRDEFYLLVLIATLGGILLA
CCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
CANHLAALFLGVELISLPLFGLVGYAYRQKRSLEAAIKYAILSAAASAFLLFGMALLYAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SGDLSFAGLGYALGGRMLAQPLVLAGLGMMLVGFGFKLSLVPFQLWTPDVYQGAPAPVST
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHCCCCCHHHH
FLATASKIAIFAVLLRLFVLLPATDSEAVRVVLGVIAFCSILFGNLMAVTQSNIKRLLGY
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSIAHLGYLLVALIAVQSEGIAIETAGVYLAGYLFASLSAFGIVSLMSSPYSGPDAESLY
HHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
SYRGLFWHKPILSAVMTVSMLSLAGIPMTLGFIGKLFVVMAGVSAGLWWLVGAVVVGSAI
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLYYYLRVAVSMYLRAPQTLIRDTPNNWALTAGGVVVLLSGVLVVLTGLFPQTLISLVQL
HHHHHHHHHHHHHHHCCHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQPLP
HCCCC
>Mature Secondary Structure 
TITPQNLIALLPLLIVGLTVVVVMLCIAWRRNHFVNATVTVIGLNAALLSLFLVAAAVP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHHCC
SDITPLVHVDGFSMLYTALVLLSALATCTFAYPWLQGYPDNRDEFYLLVLIATLGGILLA
CCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
CANHLAALFLGVELISLPLFGLVGYAYRQKRSLEAAIKYAILSAAASAFLLFGMALLYAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SGDLSFAGLGYALGGRMLAQPLVLAGLGMMLVGFGFKLSLVPFQLWTPDVYQGAPAPVST
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHCCCCCHHHH
FLATASKIAIFAVLLRLFVLLPATDSEAVRVVLGVIAFCSILFGNLMAVTQSNIKRLLGY
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSIAHLGYLLVALIAVQSEGIAIETAGVYLAGYLFASLSAFGIVSLMSSPYSGPDAESLY
HHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
SYRGLFWHKPILSAVMTVSMLSLAGIPMTLGFIGKLFVVMAGVSAGLWWLVGAVVVGSAI
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLYYYLRVAVSMYLRAPQTLIRDTPNNWALTAGGVVVLLSGVLVVLTGLFPQTLISLVQL
HHHHHHHHHHHHHHHCCHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQPLP
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA