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The map label for this gene is marA [H]

Identifier: 238920508

GI number: 238920508

Start: 2507325

End: 2507678

Strand: Direct

Name: marA [H]

Synonym: NT01EI_2620

Alternate gene names: 238920508

Gene position: 2507325-2507678 (Clockwise)

Preceding gene: 238920500

Following gene: 238920510

Centisome position: 65.77

GC content: 56.5

Gene sequence:

>354_bases
ATGTACAATACCGATTTTATCAGCGCACTACGCACCTGGATCGACAGCAACGTTGCCGCCATCTCATCCCTTGACGACGT
GGCGGCGCGCGCCGGTTACTCCAAATGGCACCTGCAGCGCATGTTTAAAGCACACACCGGAGTTCGGTTGGGGGAGTATA
TCCGCAATAAAAAGCTGGATGAGTCAGCCCGTCGGCTAAAAGTCTGCCAGGGATCGATTCTCGACATTGCCCTGTCGATG
GGCTTTGACTCCCAACGCTCCTTCACCCGCTCTTTCAAGCGGCGCTTTGACGTGACACCGGGCGTATGGAAGAAAGAGAT
GACAGCGGGGAACCCCTTGGATCGCGCCGCCTGA

Upstream 100 bases:

>100_bases
CGATCGTAACCGTGATGACACGTCAACGCATTCATGTTCCCAGGCGACTCCCACGCGCGCCGTGTCACCGACCATCGCAC
AAAAAAGTAAGGTGATTGCC

Downstream 100 bases:

>100_bases
GCGGCGGCGCCGATCGGCCCGTCGCAGACACAGTCTCTCTACTGTCTCCGCGACGGGTTATCCTGAGTCGCCGTATGGCT
CAGCGCCCCTCGGTACGCCC

Product: transposon Tn10 TetD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 117; Mature: 117

Protein sequence:

>117_residues
MYNTDFISALRTWIDSNVAAISSLDDVAARAGYSKWHLQRMFKAHTGVRLGEYIRNKKLDESARRLKVCQGSILDIALSM
GFDSQRSFTRSFKRRFDVTPGVWKKEMTAGNPLDRAA

Sequences:

>Translated_117_residues
MYNTDFISALRTWIDSNVAAISSLDDVAARAGYSKWHLQRMFKAHTGVRLGEYIRNKKLDESARRLKVCQGSILDIALSM
GFDSQRSFTRSFKRRFDVTPGVWKKEMTAGNPLDRAA
>Mature_117_residues
MYNTDFISALRTWIDSNVAAISSLDDVAARAGYSKWHLQRMFKAHTGVRLGEYIRNKKLDESARRLKVCQGSILDIALSM
GFDSQRSFTRSFKRRFDVTPGVWKKEMTAGNPLDRAA

Specific function: May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081928, Length=104, Percent_Identity=48.0769230769231, Blast_Score=105, Evalue=1e-24,
Organism=Escherichia coli, GI1790857, Length=105, Percent_Identity=48.5714285714286, Blast_Score=104, Evalue=2e-24,
Organism=Escherichia coli, GI1790497, Length=107, Percent_Identity=40.1869158878505, Blast_Score=93, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 13318; Mature: 13318

Theoretical pI: Translated: 10.68; Mature: 10.68

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNTDFISALRTWIDSNVAAISSLDDVAARAGYSKWHLQRMFKAHTGVRLGEYIRNKKLD
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHCCHH
ESARRLKVCQGSILDIALSMGFDSQRSFTRSFKRRFDVTPGVWKKEMTAGNPLDRAA
HHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCC
>Mature Secondary Structure
MYNTDFISALRTWIDSNVAAISSLDDVAARAGYSKWHLQRMFKAHTGVRLGEYIRNKKLD
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHCCHH
ESARRLKVCQGSILDIALSMGFDSQRSFTRSFKRRFDVTPGVWKKEMTAGNPLDRAA
HHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]