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The map label for this gene is gstB [H]

Identifier: 238919990

GI number: 238919990

Start: 2016282

End: 2016887

Strand: Direct

Name: gstB [H]

Synonym: NT01EI_2094

Alternate gene names: 238919990

Gene position: 2016282-2016887 (Clockwise)

Preceding gene: 238919989

Following gene: 238919996

Centisome position: 52.89

GC content: 60.23

Gene sequence:

>606_bases
ATGAAATTGTTCTATAAATCCGGGGCCTGCTCTCTCTCACCGCACATCATACTGCGTGAGGCCGGTCTGGATTTCACCAT
TGAAAGCGTGGATCTGGCCAACAAGCGTACCGAGCACGGCAGAGACTATCTAAGCATTAATCCCAAGGGGCAGGTACCAG
CGCTGCTGCTGGACGACGGCAGTCTGCTGACCGAAGGGGTAGCCATTGTGCAGTACCTGGCCGATCGGGTACCAGACCGC
TGTCTTATCCCGCCGCAGGAGACGCTGGCGCGCTATCACGCGATCGAATGGCTCAACTATATTGCCAGCGAGATCCATAA
GGGGTTCAGCCCGCTGTTCAATCCGCGCCAACCGCAGGAGAGCAAGGCGATAGCGCGCGCAGCGCTGGAGAAGCAGTTCC
ACTACCTCAACGGCGTACTCAGCGAGCGGCCCTACCTGCTGGGGCCCAGCTTCAGCGTCGCCGACGCCTATCTATTCACC
ACGCTGTGCTGGGCCAAGGCAATGCACTTCGATCTGACAGCCTGGCCGGTGCTGGCCGACTATATGACGCGTATTGCCGC
GCGGCCGGCGGTCGATGCCACGCTCTGCGCCGAGGGGTTGAAGTAG

Upstream 100 bases:

>100_bases
TACAGCGCCGCGTATAAATTCTACCTGCCACACAGACAGAGCGCCGCTGACGGACTACGCTAAAGCAGTCTACCCGTCAG
AACCGACCAAGGAGCGAGTG

Downstream 100 bases:

>100_bases
CGCGACCGACCCTGAGCGCGCAGCAGACAAGTAAAAAGGCCTCCCAGGGGAGGCCTCGTTTTTTGCGGATCGCCCGGGAT
CAGCCGTGCAGCGCCTGCGC

Product: glutathionine S-transferase

Products: NA

Alternate protein names: GST B1-1 [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MKLFYKSGACSLSPHIILREAGLDFTIESVDLANKRTEHGRDYLSINPKGQVPALLLDDGSLLTEGVAIVQYLADRVPDR
CLIPPQETLARYHAIEWLNYIASEIHKGFSPLFNPRQPQESKAIARAALEKQFHYLNGVLSERPYLLGPSFSVADAYLFT
TLCWAKAMHFDLTAWPVLADYMTRIAARPAVDATLCAEGLK

Sequences:

>Translated_201_residues
MKLFYKSGACSLSPHIILREAGLDFTIESVDLANKRTEHGRDYLSINPKGQVPALLLDDGSLLTEGVAIVQYLADRVPDR
CLIPPQETLARYHAIEWLNYIASEIHKGFSPLFNPRQPQESKAIARAALEKQFHYLNGVLSERPYLLGPSFSVADAYLFT
TLCWAKAMHFDLTAWPVLADYMTRIAARPAVDATLCAEGLK
>Mature_201_residues
MKLFYKSGACSLSPHIILREAGLDFTIESVDLANKRTEHGRDYLSINPKGQVPALLLDDGSLLTEGVAIVQYLADRVPDR
CLIPPQETLARYHAIEWLNYIASEIHKGFSPLFNPRQPQESKAIARAALEKQFHYLNGVLSERPYLLGPSFSVADAYLFT
TLCWAKAMHFDLTAWPVLADYMTRIAARPAVDATLCAEGLK

Specific function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787923, Length=201, Percent_Identity=59.7014925373134, Blast_Score=231, Evalue=3e-62,
Organism=Escherichia coli, GI1788640, Length=195, Percent_Identity=30.2564102564103, Blast_Score=68, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24645375, Length=197, Percent_Identity=28.9340101522843, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45553325, Length=197, Percent_Identity=28.9340101522843, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355859, Length=197, Percent_Identity=28.9340101522843, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =2.5.1.18 [H]

Molecular weight: Translated: 22435; Mature: 22435

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFYKSGACSLSPHIILREAGLDFTIESVDLANKRTEHGRDYLSINPKGQVPALLLDDG
CEEEECCCCCCCCCCEEEEECCCCEEEEHHHHHHHHHHCCCCEEEECCCCCCCEEEECCC
SLLTEGVAIVQYLADRVPDRCLIPPQETLARYHAIEWLNYIASEIHKGFSPLFNPRQPQE
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
SKAIARAALEKQFHYLNGVLSERPYLLGPSFSVADAYLFTTLCWAKAMHFDLTAWPVLAD
HHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
YMTRIAARPAVDATLCAEGLK
HHHHHHCCCCCHHHHHHCCCC
>Mature Secondary Structure
MKLFYKSGACSLSPHIILREAGLDFTIESVDLANKRTEHGRDYLSINPKGQVPALLLDDG
CEEEECCCCCCCCCCEEEEECCCCEEEEHHHHHHHHHHCCCCEEEECCCCCCCEEEECCC
SLLTEGVAIVQYLADRVPDRCLIPPQETLARYHAIEWLNYIASEIHKGFSPLFNPRQPQE
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
SKAIARAALEKQFHYLNGVLSERPYLLGPSFSVADAYLFTTLCWAKAMHFDLTAWPVLAD
HHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
YMTRIAARPAVDATLCAEGLK
HHHHHHCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8761466; 8436105; 2661269; 8645008; 9655824 [H]