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The map label for this gene is tppB [H]

Identifier: 238919989

GI number: 238919989

Start: 2014694

End: 2016133

Strand: Direct

Name: tppB [H]

Synonym: NT01EI_2093

Alternate gene names: 238919989

Gene position: 2014694-2016133 (Clockwise)

Preceding gene: 238919988

Following gene: 238919990

Centisome position: 52.85

GC content: 59.24

Gene sequence:

>1440_bases
GTGAGTCTTAACGCATTTAAACAACCCCGCGCTTTTTATCTGATTTTCTCTATCGAACTGTGGGAGCGTTTCGGCTATTA
CGGCCTGCAGGGCATCATGGCCGTTTATCTGGTCAAGATGCTGGGCATGAGCGAGGCCGACTCCATTACCCTGTTCTCCT
CCTTCAGCGCCCTGGTATACGGCTTTGTCGCTATTGGCGGCTGGCTGGGTGACAAGGTGCTGGGCGCCAAGCGTGTCATC
ATGCTCGGCGCGCTGGTTCTGGCCATCGGCTATGCCTTTGTCGCCTACTCCGGCCATGAGCTGTCAATGGTCTACGTAGG
GATGGCAACCATCGCGGTCGGTAACGGCCTGTTCAAGGCCAACCCCTCCTCGCTACTCTCCACCTGCTATGAGAAAAACG
ATCCGCGCCTGGACGGCGCCTTCACCATGTACTACATGTCGGTGAACATCGGCTCCTTCTTCTCCATGCTGGCAACCCCG
TGGCTGGCGGCCCGCTTTGGCTGGAGCGTCGCCTTCTCCCTGAGCGTCGTGGGCATGCTGATCACCCTGGTCAACTTTAT
GATGTGCCGTCGCTGGGTGAAAGATCAGGGCTCCAAGCCGGACTTCGCCCCGCTGCAGGTCGGCAAGCTGATGATGACCT
TAGTCGGCGTAGTGATCCTGGTTGCCATCTCAACCTGGCTGCTGCATAACCAGACCATCGCCCGCTGGGCGCTGGCCATC
ATTTCCGCCTGCATCGTCCTGATCTTCGCTAAAGAGACCTTTGCACTGCAGGGCGGCGCGCGCCGTAAGATGATCGTCGC
CTTCCTGCTGATGCTGGAGGCCGTGGTCTTCTTCGTATTGTATAGCCAGATGCCGACCTCGCTGAACTTCTTCGCCATCC
ATAACGTTGAACACAGCATCTTCGGCATCGCGTTCGAGCCGGAGCAGTATCAGGCGCTGAACCCGTTCTGGATCATGGTC
GCCAGCCCGATCCTGGCCGCTATCTACAACAAGATGGGGGACCGCCTGCCGATGCCGCACAAATTTGCTATCGGTATGGT
ATTGTGCTCCGGCGCGTTCCTGGTGCTGCCGTGGGGTGCCTCCTTCGCCAATGAAGCGGGTATTGTGTCGGTTAACTGGC
TGATCCTGAGCTATGCGCTGCAGAGTATCGGCGAACTGATGATCTCCGGTCTGGGTCTGGCCATGGTGGCACAGCTGGTG
CCGCAGCGACTGATGGGCTTTATCATGGGCTCTTGGTTCCTGACCACCGCCGCCGCGGCGCTGATCGCCGGTAAAGTGGC
GGCGCTGACCGCCGTGCCGGGGGGCGAGGTTGCCGATCCCCACGCGTCACTGGCTATCTATAGCCACGTATTTATGCAGA
TCGGCATCGCTACCGCCGTCATCGCCGTGCTGATGCTGCTGACCGCACCGAAGCTGAACCGTATGACCCTGGGCGATTGA

Upstream 100 bases:

>100_bases
TGTTTTTTAAACATACGCCGTGGCCGTTACCCGCCTTCAGGCGGGCATGAAAAACCAGAGGTAACTTGTGTCAAACGCAA
ACAACAACCAAGCGGAAAGC

Downstream 100 bases:

>100_bases
TTTCTCCCCCCGCTAAAAAGGCGCCCTCTGTGGCGCCTTTTTTGTCTCTACAGCGCCGCGTATAAATTCTACCTGCCACA
CAGACAGAGCGCCGCTGACG

Product: tripeptide transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MSLNAFKQPRAFYLIFSIELWERFGYYGLQGIMAVYLVKMLGMSEADSITLFSSFSALVYGFVAIGGWLGDKVLGAKRVI
MLGALVLAIGYAFVAYSGHELSMVYVGMATIAVGNGLFKANPSSLLSTCYEKNDPRLDGAFTMYYMSVNIGSFFSMLATP
WLAARFGWSVAFSLSVVGMLITLVNFMMCRRWVKDQGSKPDFAPLQVGKLMMTLVGVVILVAISTWLLHNQTIARWALAI
ISACIVLIFAKETFALQGGARRKMIVAFLLMLEAVVFFVLYSQMPTSLNFFAIHNVEHSIFGIAFEPEQYQALNPFWIMV
ASPILAAIYNKMGDRLPMPHKFAIGMVLCSGAFLVLPWGASFANEAGIVSVNWLILSYALQSIGELMISGLGLAMVAQLV
PQRLMGFIMGSWFLTTAAAALIAGKVAALTAVPGGEVADPHASLAIYSHVFMQIGIATAVIAVLMLLTAPKLNRMTLGD

Sequences:

>Translated_479_residues
MSLNAFKQPRAFYLIFSIELWERFGYYGLQGIMAVYLVKMLGMSEADSITLFSSFSALVYGFVAIGGWLGDKVLGAKRVI
MLGALVLAIGYAFVAYSGHELSMVYVGMATIAVGNGLFKANPSSLLSTCYEKNDPRLDGAFTMYYMSVNIGSFFSMLATP
WLAARFGWSVAFSLSVVGMLITLVNFMMCRRWVKDQGSKPDFAPLQVGKLMMTLVGVVILVAISTWLLHNQTIARWALAI
ISACIVLIFAKETFALQGGARRKMIVAFLLMLEAVVFFVLYSQMPTSLNFFAIHNVEHSIFGIAFEPEQYQALNPFWIMV
ASPILAAIYNKMGDRLPMPHKFAIGMVLCSGAFLVLPWGASFANEAGIVSVNWLILSYALQSIGELMISGLGLAMVAQLV
PQRLMGFIMGSWFLTTAAAALIAGKVAALTAVPGGEVADPHASLAIYSHVFMQIGIATAVIAVLMLLTAPKLNRMTLGD
>Mature_478_residues
SLNAFKQPRAFYLIFSIELWERFGYYGLQGIMAVYLVKMLGMSEADSITLFSSFSALVYGFVAIGGWLGDKVLGAKRVIM
LGALVLAIGYAFVAYSGHELSMVYVGMATIAVGNGLFKANPSSLLSTCYEKNDPRLDGAFTMYYMSVNIGSFFSMLATPW
LAARFGWSVAFSLSVVGMLITLVNFMMCRRWVKDQGSKPDFAPLQVGKLMMTLVGVVILVAISTWLLHNQTIARWALAII
SACIVLIFAKETFALQGGARRKMIVAFLLMLEAVVFFVLYSQMPTSLNFFAIHNVEHSIFGIAFEPEQYQALNPFWIMVA
SPILAAIYNKMGDRLPMPHKFAIGMVLCSGAFLVLPWGASFANEAGIVSVNWLILSYALQSIGELMISGLGLAMVAQLVP
QRLMGFIMGSWFLTTAAAALIAGKVAALTAVPGGEVADPHASLAIYSHVFMQIGIATAVIAVLMLLTAPKLNRMTLGD

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=388, Percent_Identity=23.9690721649485, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI226371746, Length=359, Percent_Identity=24.5125348189415, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI226371748, Length=351, Percent_Identity=23.6467236467236, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1787922, Length=476, Percent_Identity=80.0420168067227, Blast_Score=781, Evalue=0.0,
Organism=Escherichia coli, GI1789911, Length=473, Percent_Identity=52.6427061310782, Blast_Score=506, Evalue=1e-144,
Organism=Escherichia coli, GI1790572, Length=470, Percent_Identity=30.6382978723404, Blast_Score=188, Evalue=5e-49,
Organism=Escherichia coli, GI1786927, Length=468, Percent_Identity=29.2735042735043, Blast_Score=182, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI17569141, Length=372, Percent_Identity=26.3440860215054, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17541704, Length=403, Percent_Identity=24.8138957816377, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71987453, Length=372, Percent_Identity=22.5806451612903, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24639585, Length=337, Percent_Identity=27.5964391691395, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24639583, Length=334, Percent_Identity=27.5449101796407, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24639581, Length=334, Percent_Identity=27.5449101796407, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI28571098, Length=369, Percent_Identity=26.5582655826558, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28571102, Length=369, Percent_Identity=26.5582655826558, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28571100, Length=369, Percent_Identity=26.5582655826558, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 52116; Mature: 51985

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS50850 MFS ; PS01022 PTR2_1 ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNAFKQPRAFYLIFSIELWERFGYYGLQGIMAVYLVKMLGMSEADSITLFSSFSALVY
CCCCCCCCCCEEEEEEEHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
GFVAIGGWLGDKVLGAKRVIMLGALVLAIGYAFVAYSGHELSMVYVGMATIAVGNGLFKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCCCC
NPSSLLSTCYEKNDPRLDGAFTMYYMSVNIGSFFSMLATPWLAARFGWSVAFSLSVVGML
CHHHHHHHHHHCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITLVNFMMCRRWVKDQGSKPDFAPLQVGKLMMTLVGVVILVAISTWLLHNQTIARWALAI
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
ISACIVLIFAKETFALQGGARRKMIVAFLLMLEAVVFFVLYSQMPTSLNFFAIHNVEHSI
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCE
FGIAFEPEQYQALNPFWIMVASPILAAIYNKMGDRLPMPHKFAIGMVLCSGAFLVLPWGA
EEEEECCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCC
SFANEAGIVSVNWLILSYALQSIGELMISGLGLAMVAQLVPQRLMGFIMGSWFLTTAAAA
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIAGKVAALTAVPGGEVADPHASLAIYSHVFMQIGIATAVIAVLMLLTAPKLNRMTLGD
HHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SLNAFKQPRAFYLIFSIELWERFGYYGLQGIMAVYLVKMLGMSEADSITLFSSFSALVY
CCCCCCCCCEEEEEEEHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
GFVAIGGWLGDKVLGAKRVIMLGALVLAIGYAFVAYSGHELSMVYVGMATIAVGNGLFKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCCCC
NPSSLLSTCYEKNDPRLDGAFTMYYMSVNIGSFFSMLATPWLAARFGWSVAFSLSVVGML
CHHHHHHHHHHCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITLVNFMMCRRWVKDQGSKPDFAPLQVGKLMMTLVGVVILVAISTWLLHNQTIARWALAI
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
ISACIVLIFAKETFALQGGARRKMIVAFLLMLEAVVFFVLYSQMPTSLNFFAIHNVEHSI
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCE
FGIAFEPEQYQALNPFWIMVASPILAAIYNKMGDRLPMPHKFAIGMVLCSGAFLVLPWGA
EEEEECCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCC
SFANEAGIVSVNWLILSYALQSIGELMISGLGLAMVAQLVPQRLMGFIMGSWFLTTAAAA
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIAGKVAALTAVPGGEVADPHASLAIYSHVFMQIGIATAVIAVLMLLTAPKLNRMTLGD
HHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA