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The map label for this gene is tcp [H]

Identifier: 238919867

GI number: 238919867

Start: 1897943

End: 1899733

Strand: Direct

Name: tcp [H]

Synonym: NT01EI_1971

Alternate gene names: 238919867

Gene position: 1897943-1899733 (Clockwise)

Preceding gene: 238919866

Following gene: 238919868

Centisome position: 49.78

GC content: 55.83

Gene sequence:

>1791_bases
ATGTTCGATTCCATTCGGGCACGGATTCTCGCGACAACCGGCGTCATTGTCGCAGCGTCGCTTTGTGTCAATACGTTGAT
TAATTATCGGATTGCCAGCGACTCTAACGCAAAAGCCCTTCAACATACCCTAATATCTTTAACTGCCAGCCATACCGCTA
CCGTACGCCAGTGGGTCGAAAACAAAACGGCGCTGATCGCCTCACTGACACCCCATGTCGGGGACAGCGATCCCCGGCCG
CTATTAAAACAGATAGCCGACGCCGGTGGCTTTATCAGTGTAGATATGGGGTACTCCAACAGGGTGGAGATCTCCTCCGA
TCCCTCCAGCATCCCCCCGGGCTTCGATCCCACAACCCGCGCCTGGTTTATCAATGCCAGAAAAGTAGGGCATCCGATCG
TAACCGAACCTTATATGGATGCAAATACCCATACATTGGTGGTGACCTTTGCCGCACCTGGTCCACAGGACACGCCAATC
AGCGGTGTCGTTGAGGGCGATGTACATATGGATAAAGTGATTGCCAACGTGCGATCCATCCACCCCACAAAACACAGCTT
TGGTATGCTGCTTAATGCTGACGGTACCATCATCGCCCACCCCAATCAGCAGCTGACGCTGAAATCACTGGCTGACATCG
CGCCACGCCTGAGCCTGACCCAGCTGTTAACCTCCGGTAAACCTGTGGAGGCGATCATTTCCGGCCGCAATGCGCTGTTG
TTGGCAATGCCGATCCACGGAACCAGTTGGTATACCGTTGTAGCTATGGATGATACAGAGGCTACAGATGGAATGCGTTC
ACTGCTGCTGGCCTCCTGCATTGCACTGCTGGTTCTGATCGTGCTCTCTACACTGGTGATTGGTATCGTCACGCGTCGGG
CGCTGCGTCCGTTGTTCCATATCCGTCAGGCGATGGAAAACATCGGCGCCGGCAACAACGCAGATTTGACCAAGCGGCTG
GATGTGCAGGGGAAAGATGAGGTATCGCAGATCGCCCGTGCATTTAACCAATTCGTGGATAAGCTGGCCAACGTGATGAT
TTCTATTCACAGTACCAGCGAGTCAGTTCGTATTGCCGCGCGGGAAATCGCTGCCGGTAACGAGGACCTCTCTAGCCGAA
CCGAGTCAGCGGCGGCCAGTCTGCAGCAGACCTCGGCGGCACTGGAGCAGATCTCTGCAACCGTTGCACAGTCGGCGACC
TCTGCCCAGCAGGCCAATGAGTCCGTCAGCTCTGCTGTTCAGGTAGCGCAGCGCGGTGGCAAGATGATCTCGCAGGTCAT
CGAAACCATGTCCTCGATTGAGGTTGCCTCCGGTAAAATCGGTGACATCACCGGAGTCATCGATGGCATTGCATTCCAAA
CCAATATACTGGCGCTCAACGCCGCGGTTGAAGCCGCCCGTGCCGGCGAGCAGGGGCGTGGGTTTGCCGTTGTCGCCGGC
GAAGTCAGAACGTTGGCTCAGCGCAGTGCCCAGGCAGCCAAAGAGATCAAAAATCTGATCGACTCAACCGTAACCAGCGT
CGCCTCCGGCTCACACCAGGTACGCCAGAGCGGTGAAACCATGACAGATATTGTTAATAGTGTCGGCGCCGTCAGTGCCA
TTATGGGTGAGATCACCAACGCGGCTGAAGAGCAAAACCGCGGCATCAGTGAGATCAACAGTGCGGTGATCCAGCTGGAT
ACGATGGTACAGCAGAACGCCGCTCTGGTTGAGGAATCAACCGCGGCCTCCGCCGCGCTGCAAGGGCAGGCAAGTGAGCT
GGCCGATACTGTAGGCCAGTTCAAGATGTAA

Upstream 100 bases:

>100_bases
TTACATCAGATAAAATCACTCAAGTTTAAAGGAAGTCTGCCGTTATCAGTAAGACTGACCATTTAAAATTTATCTTACTT
ACTACACAGGCAGGCCTATT

Downstream 100 bases:

>100_bases
TCCGTTTTATTTATATTGTACCGTTCGGGAGGGCTGCATTAATAGCAGCCCTTTATTTTTTATCTCTATTTACGACATTT
TTCGGCACACCTGAACGTTT

Product: methyl-accepting chemotaxis sensory transducer with Cache sensor

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 596; Mature: 596

Protein sequence:

>596_residues
MFDSIRARILATTGVIVAASLCVNTLINYRIASDSNAKALQHTLISLTASHTATVRQWVENKTALIASLTPHVGDSDPRP
LLKQIADAGGFISVDMGYSNRVEISSDPSSIPPGFDPTTRAWFINARKVGHPIVTEPYMDANTHTLVVTFAAPGPQDTPI
SGVVEGDVHMDKVIANVRSIHPTKHSFGMLLNADGTIIAHPNQQLTLKSLADIAPRLSLTQLLTSGKPVEAIISGRNALL
LAMPIHGTSWYTVVAMDDTEATDGMRSLLLASCIALLVLIVLSTLVIGIVTRRALRPLFHIRQAMENIGAGNNADLTKRL
DVQGKDEVSQIARAFNQFVDKLANVMISIHSTSESVRIAAREIAAGNEDLSSRTESAAASLQQTSAALEQISATVAQSAT
SAQQANESVSSAVQVAQRGGKMISQVIETMSSIEVASGKIGDITGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAG
EVRTLAQRSAQAAKEIKNLIDSTVTSVASGSHQVRQSGETMTDIVNSVGAVSAIMGEITNAAEEQNRGISEINSAVIQLD
TMVQQNAALVEESTAASAALQGQASELADTVGQFKM

Sequences:

>Translated_596_residues
MFDSIRARILATTGVIVAASLCVNTLINYRIASDSNAKALQHTLISLTASHTATVRQWVENKTALIASLTPHVGDSDPRP
LLKQIADAGGFISVDMGYSNRVEISSDPSSIPPGFDPTTRAWFINARKVGHPIVTEPYMDANTHTLVVTFAAPGPQDTPI
SGVVEGDVHMDKVIANVRSIHPTKHSFGMLLNADGTIIAHPNQQLTLKSLADIAPRLSLTQLLTSGKPVEAIISGRNALL
LAMPIHGTSWYTVVAMDDTEATDGMRSLLLASCIALLVLIVLSTLVIGIVTRRALRPLFHIRQAMENIGAGNNADLTKRL
DVQGKDEVSQIARAFNQFVDKLANVMISIHSTSESVRIAAREIAAGNEDLSSRTESAAASLQQTSAALEQISATVAQSAT
SAQQANESVSSAVQVAQRGGKMISQVIETMSSIEVASGKIGDITGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAG
EVRTLAQRSAQAAKEIKNLIDSTVTSVASGSHQVRQSGETMTDIVNSVGAVSAIMGEITNAAEEQNRGISEINSAVIQLD
TMVQQNAALVEESTAASAALQGQASELADTVGQFKM
>Mature_596_residues
MFDSIRARILATTGVIVAASLCVNTLINYRIASDSNAKALQHTLISLTASHTATVRQWVENKTALIASLTPHVGDSDPRP
LLKQIADAGGFISVDMGYSNRVEISSDPSSIPPGFDPTTRAWFINARKVGHPIVTEPYMDANTHTLVVTFAAPGPQDTPI
SGVVEGDVHMDKVIANVRSIHPTKHSFGMLLNADGTIIAHPNQQLTLKSLADIAPRLSLTQLLTSGKPVEAIISGRNALL
LAMPIHGTSWYTVVAMDDTEATDGMRSLLLASCIALLVLIVLSTLVIGIVTRRALRPLFHIRQAMENIGAGNNADLTKRL
DVQGKDEVSQIARAFNQFVDKLANVMISIHSTSESVRIAAREIAAGNEDLSSRTESAAASLQQTSAALEQISATVAQSAT
SAQQANESVSSAVQVAQRGGKMISQVIETMSSIEVASGKIGDITGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAG
EVRTLAQRSAQAAKEIKNLIDSTVTSVASGSHQVRQSGETMTDIVNSVGAVSAIMGEITNAAEEQNRGISEINSAVIQLD
TMVQQNAALVEESTAASAALQGQASELADTVGQFKM

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=324, Percent_Identity=47.2222222222222, Blast_Score=268, Evalue=5e-73,
Organism=Escherichia coli, GI1788194, Length=329, Percent_Identity=48.936170212766, Blast_Score=267, Evalue=1e-72,
Organism=Escherichia coli, GI1788195, Length=307, Percent_Identity=51.4657980456026, Blast_Score=261, Evalue=1e-70,
Organism=Escherichia coli, GI2367378, Length=355, Percent_Identity=43.6619718309859, Blast_Score=258, Evalue=1e-69,
Organism=Escherichia coli, GI1789453, Length=320, Percent_Identity=40.9375, Blast_Score=200, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 62748; Mature: 62748

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDSIRARILATTGVIVAASLCVNTLINYRIASDSNAKALQHTLISLTASHTATVRQWVE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHC
NKTALIASLTPHVGDSDPRPLLKQIADAGGFISVDMGYSNRVEISSDPSSIPPGFDPTTR
CCCEEEEECCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCEEECCCCCCCCCCCCCCCC
AWFINARKVGHPIVTEPYMDANTHTLVVTFAAPGPQDTPISGVVEGDVHMDKVIANVRSI
EEEEEHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEECCHHHHHHHHHHHHC
HPTKHSFGMLLNADGTIIAHPNQQLTLKSLADIAPRLSLTQLLTSGKPVEAIISGRNALL
CCCCHHCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEE
LAMPIHGTSWYTVVAMDDTEATDGMRSLLLASCIALLVLIVLSTLVIGIVTRRALRPLFH
EEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRQAMENIGAGNNADLTKRLDVQGKDEVSQIARAFNQFVDKLANVMISIHSTSESVRIAA
HHHHHHHCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHH
REIAAGNEDLSSRTESAAASLQQTSAALEQISATVAQSATSAQQANESVSSAVQVAQRGG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMISQVIETMSSIEVASGKIGDITGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAG
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCEEEEHH
EVRTLAQRSAQAAKEIKNLIDSTVTSVASGSHQVRQSGETMTDIVNSVGAVSAIMGEITN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AAEEQNRGISEINSAVIQLDTMVQQNAALVEESTAASAALQGQASELADTVGQFKM
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
>Mature Secondary Structure
MFDSIRARILATTGVIVAASLCVNTLINYRIASDSNAKALQHTLISLTASHTATVRQWVE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHC
NKTALIASLTPHVGDSDPRPLLKQIADAGGFISVDMGYSNRVEISSDPSSIPPGFDPTTR
CCCEEEEECCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCEEECCCCCCCCCCCCCCCC
AWFINARKVGHPIVTEPYMDANTHTLVVTFAAPGPQDTPISGVVEGDVHMDKVIANVRSI
EEEEEHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEECCHHHHHHHHHHHHC
HPTKHSFGMLLNADGTIIAHPNQQLTLKSLADIAPRLSLTQLLTSGKPVEAIISGRNALL
CCCCHHCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEE
LAMPIHGTSWYTVVAMDDTEATDGMRSLLLASCIALLVLIVLSTLVIGIVTRRALRPLFH
EEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRQAMENIGAGNNADLTKRLDVQGKDEVSQIARAFNQFVDKLANVMISIHSTSESVRIAA
HHHHHHHCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHH
REIAAGNEDLSSRTESAAASLQQTSAALEQISATVAQSATSAQQANESVSSAVQVAQRGG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMISQVIETMSSIEVASGKIGDITGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAG
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCEEEEHH
EVRTLAQRSAQAAKEIKNLIDSTVTSVASGSHQVRQSGETMTDIVNSVGAVSAIMGEITN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AAEEQNRGISEINSAVIQLDTMVQQNAALVEESTAASAALQGQASELADTVGQFKM
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]