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The map label for this gene is tonB [H]

Identifier: 238919581

GI number: 238919581

Start: 1640208

End: 1641059

Strand: Direct

Name: tonB [H]

Synonym: NT01EI_1680

Alternate gene names: 238919581

Gene position: 1640208-1641059 (Clockwise)

Preceding gene: 238919579

Following gene: 238919583

Centisome position: 43.02

GC content: 63.38

Gene sequence:

>852_bases
TTGTCGGCTGATAAATTAACCCTGAAGCAATTTTTCCTGGCTCGTCGTCTTTCTTGGCCGATGACGCTATCGGTATCCCT
ACATGCCTCGCTGATTGCCGGACTGCTGTATGCCTCCTACCATGAGATCCGTCCACAGCCTGCCGGTGATGCGGGGCAGA
TCCAGGCGATAATGGTCAATCCAGCCATGTTTTCCGTCGCTGGTGGCGCGGCGAGCGTGGCGCCACCGGCGGCGGCACCT
CCTGCGACGCAGGGGACTGGATTGGCGCAGGCAGCGCTGCCGAGCGTCCCCGTCCCCCAAGAGTATAAGGAGAAAGATGC
GCCGTCGCCCGAGAGACAGCAACCGAGACCAAACGAAAGGACGCCGCCTCGCAAACGGGAGGTGAAACCGGCGCCGCCGA
AGGCGCAACCGCCGGTACAGACGCGGCAGGCGACGGTGGCCAAGGTGGAATCGCCGATGCCGCATGCAGCGATGATGCCG
GACAAGGTACAAGGCGCAGCGTCAAAGGTGACAGCGGAGAGTGCTACGGGGACTTTACTAAACGCAGCACCGCAGGCAGC
CGCCGGTCGTTCGGTGGCTGTGGGCGCACCTCAAGCCGTCAGTCGTCCTGAGCCGGCCTATCCCCAGCGTGCGCTGGCGC
TGCATATTGAGGGGCGAGTGAAGCTGCGTTTTGACGTCGATAGTGAGGGGCGCGTCGGCAATGTCAGTATCCTGTCGGCC
GAGCCGCCCGGGGTATTTGAGCGGGAGGTCAAGCGCGCCGCCCGCCGTTGGCGTTACCAGCCTGGACGCCCGGGGCAGAA
TGTTCAGGTGACTGTCTATTTTCGGATCGATGGCCGGGCGGCCGTCGAATGA

Upstream 100 bases:

>100_bases
TTTATACCCTCTGACAGTTCCCAGTTGAATATGATTGCTATTTGCATTTAAAATTGACAACAACACGCGATGCCCATTTA
CCCATTGAGTTACCAATACC

Downstream 100 bases:

>100_bases
GGGCTAGCCGGGCCCGTGATGGCCCGGCTTAGGGTCTTATTGTGCAGCGTCGTTACGGAAGTTGACTTTCCCAGCTGGCA
GCGAACGGGATTTATTCGCG

Product: protein TonB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MSADKLTLKQFFLARRLSWPMTLSVSLHASLIAGLLYASYHEIRPQPAGDAGQIQAIMVNPAMFSVAGGAASVAPPAAAP
PATQGTGLAQAALPSVPVPQEYKEKDAPSPERQQPRPNERTPPRKREVKPAPPKAQPPVQTRQATVAKVESPMPHAAMMP
DKVQGAASKVTAESATGTLLNAAPQAAAGRSVAVGAPQAVSRPEPAYPQRALALHIEGRVKLRFDVDSEGRVGNVSILSA
EPPGVFEREVKRAARRWRYQPGRPGQNVQVTVYFRIDGRAAVE

Sequences:

>Translated_283_residues
MSADKLTLKQFFLARRLSWPMTLSVSLHASLIAGLLYASYHEIRPQPAGDAGQIQAIMVNPAMFSVAGGAASVAPPAAAP
PATQGTGLAQAALPSVPVPQEYKEKDAPSPERQQPRPNERTPPRKREVKPAPPKAQPPVQTRQATVAKVESPMPHAAMMP
DKVQGAASKVTAESATGTLLNAAPQAAAGRSVAVGAPQAVSRPEPAYPQRALALHIEGRVKLRFDVDSEGRVGNVSILSA
EPPGVFEREVKRAARRWRYQPGRPGQNVQVTVYFRIDGRAAVE
>Mature_282_residues
SADKLTLKQFFLARRLSWPMTLSVSLHASLIAGLLYASYHEIRPQPAGDAGQIQAIMVNPAMFSVAGGAASVAPPAAAPP
ATQGTGLAQAALPSVPVPQEYKEKDAPSPERQQPRPNERTPPRKREVKPAPPKAQPPVQTRQATVAKVESPMPHAAMMPD
KVQGAASKVTAESATGTLLNAAPQAAAGRSVAVGAPQAVSRPEPAYPQRALALHIEGRVKLRFDVDSEGRVGNVSILSAE
PPGVFEREVKRAARRWRYQPGRPGQNVQVTVYFRIDGRAAVE

Specific function: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates such as cobalamin, and various iron compounds (such as iron dicitrate, enterochelin, aerobac

COG id: COG0810

COG function: function code M; Periplasmic protein TonB, links inner and outer membranes

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB family [H]

Homologues:

Organism=Escherichia coli, GI1787505, Length=93, Percent_Identity=56.989247311828, Blast_Score=112, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003538
- InterPro:   IPR006260 [H]

Pfam domain/function: PF03544 TonB [H]

EC number: NA

Molecular weight: Translated: 30141; Mature: 30010

Theoretical pI: Translated: 10.86; Mature: 10.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADKLTLKQFFLARRLSWPMTLSVSLHASLIAGLLYASYHEIRPQPAGDAGQIQAIMVN
CCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEC
PAMFSVAGGAASVAPPAAAPPATQGTGLAQAALPSVPVPQEYKEKDAPSPERQQPRPNER
CHHEEECCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCCC
TPPRKREVKPAPPKAQPPVQTRQATVAKVESPMPHAAMMPDKVQGAASKVTAESATGTLL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHCCCCCHHH
NAAPQAAAGRSVAVGAPQAVSRPEPAYPQRALALHIEGRVKLRFDVDSEGRVGNVSILSA
HCCCCHHCCCEEECCCCHHCCCCCCCCCCEEEEEEECCEEEEEEECCCCCCCCEEEEEEC
EPPGVFEREVKRAARRWRYQPGRPGQNVQVTVYFRIDGRAAVE
CCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCEECC
>Mature Secondary Structure 
SADKLTLKQFFLARRLSWPMTLSVSLHASLIAGLLYASYHEIRPQPAGDAGQIQAIMVN
CCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEC
PAMFSVAGGAASVAPPAAAPPATQGTGLAQAALPSVPVPQEYKEKDAPSPERQQPRPNER
CHHEEECCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCCC
TPPRKREVKPAPPKAQPPVQTRQATVAKVESPMPHAAMMPDKVQGAASKVTAESATGTLL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHCCCCCHHH
NAAPQAAAGRSVAVGAPQAVSRPEPAYPQRALALHIEGRVKLRFDVDSEGRVGNVSILSA
HCCCCHHCCCEEECCCCHHCCCCCCCCCCEEEEEEECCEEEEEEECCCCCCCCEEEEEEC
EPPGVFEREVKRAARRWRYQPGRPGQNVQVTVYFRIDGRAAVE
CCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6310567; 9097039; 9278503; 1885532; 8316087; 11328822 [H]