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The map label for this gene is ychM [C]

Identifier: 238919583

GI number: 238919583

Start: 1642378

End: 1644126

Strand: Direct

Name: ychM [C]

Synonym: NT01EI_1682

Alternate gene names: 238919583

Gene position: 1642378-1644126 (Clockwise)

Preceding gene: 238919581

Following gene: 238919586

Centisome position: 43.08

GC content: 60.66

Gene sequence:

>1749_bases
ATGCAATGTGATTTTCTGCGCCGCGGGATGCCGGGGTTGTACCAACTGACGAAATACCGGCGGGAGTGGCTGGCCGACGA
TCTGCGCGCCGGGCTATCGGTTGCCGCCGTTGCACTGCCGACGGCGTTGGCCTATGCCGATCTGGTCGGGGTAACGGCGG
TGGTGGGGATTTACTCCTGTATCCTGCCGATGATTGCCTATGCGCTGTTTGGCTCCTCACGCCAGGTGATCGTCGGGCCA
GATGCGGCCACCTGTGCGGTGATTGCTGCTGTAGTGACTCCGCTGGCGGCAGGCGATCCGCAGCGGCTGTGGCAGCTGTG
CGTTATGATGACCCTGATGACCGGCCTGTGGTGCCTTGTCGCCAGCCGCTTTCGCCTTGGCGCGCTGGCGGATCTTCTGT
CACGGCCCATTCTGACCGGTTTGCTCAATGGTCTGGCTATCACCATCATGATCGATCAGCTGGCGAAGATGCTGGGCTAC
CAGCCCGCCTCGCGCGAGGTGATTGAACGCATTCTCTCGCTGCCCCACGACCTGCTCTCCAGCCATTGGCCGACACTGCT
TCTGTCGCTGCTGACCCTGCTGGTCCTGCTGGGGCTGCGCCGTCTGCGTCCCGGCTGGCCAGCGGCGTTACTGGTGATCA
TCCTCGCCATGCTGCTGGTTTGGCTGGGGGGGCTGCAGCGCTTTGGCATTCAAACGATTAGCGGTCTTGACGGTACGCTG
CCGGTGGTACAGTGGCCTAATTTTCAGCCTGCGCTGCTGCGTGATCTGGTGATGCCATCCCTGAACCTGGCACTGATAAG
TTTTGTCAGCCTGATGCTGACGGCGCGCAGCTTTGCCTCTAAAAATGGCTATGAAGTTAACCCAGACGCGGAGTTCCGCG
CGCTGGGTGTTGCCAATATCGTGTCGGCGCTTTCGCAGGGGTTCGCCATCAGCGGCGCCAGCTCCCGTACCGCGGTCAAC
GATGCCAACGGCGGTAAAAGTCAGCTGGTCTCCATCGTGGCCGCGCTGTCTATCGCGGCGGTGCTGCTGCTGTTGGGGAA
CTTGCTGCGCTATATTCCGGTGGCTGTGCTCGGCGTGGTATTGGTGTACGCTTCCTGGCTGCTGCTGGATATCCGCTCTT
TGGTGAGCCTGCGTAAACACAATCCATCGGCCTTTCGTCTGGCGCTGTTTACCTTTGCCAGCGTGCTGTTGGTGGGGGTT
ATGCCAGGGATTGGGTTGGCCGTACTGCTGGGACTGCTGCAGTTTTTCCGTACGGTGTTCCGTCCCAGCGAACAACTGCT
GGGGGTGAATGAGGAGGGAATGATCCACTCGCTCGGCAACGGTAATCAGGTGCGGGCGGTTGAGGGGGTGCTGATCTACC
GATTTAACTCGCCGCTGACCTATTTCAATATCGCCTATTTTAAGCGCCGGGTCCTGAATCTGGTCGACGGAATGCCGTTT
CAGCCGGAGTGGGTGGTGATCGATGCGGTATCCTGCTTTACCTACCCCGACATTAGCGTGTTGGCGGGGATCGATGAACT
GAAGCGCGACCTGCGCCAGCGGCGGGTTCATCTGGTGCTGGCCGGGCGTAAAACCGACCTAAAGCGCTGGTTTGGCCGCA
GTCGGGCCACTGGGGAAGAGAAGGGGCTGCTATTTGTCGCCGATCTGTATCTGGCGCTGAAGCTGATCCAAAGCAGTCGG
TGTGCCCATGCCGATGGTGTGGACGGATCCCCGGGAGCCGCTCAGAACGGTACGGTTGCGCCTCGCTGA

Upstream 100 bases:

>100_bases
TTTTGCAAAAAATTACACGTGAGCCCACACACCTGCCGACTTGACCAAGTGCGTCAGCCTATCCATGATGGAGATGGGCG
CCTCTTAGGATTACGACGTT

Downstream 100 bases:

>100_bases
CGTCCCCGGTTAACCATCACTTATATAGAGAAATGTATTTTCTATAGTAGACAAATCTGTTATTGAACAGCTGCTCTCCG
GTGAGCAGGTCGCCATCTTT

Product: hypothetical protein

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 582; Mature: 582

Protein sequence:

>582_residues
MQCDFLRRGMPGLYQLTKYRREWLADDLRAGLSVAAVALPTALAYADLVGVTAVVGIYSCILPMIAYALFGSSRQVIVGP
DAATCAVIAAVVTPLAAGDPQRLWQLCVMMTLMTGLWCLVASRFRLGALADLLSRPILTGLLNGLAITIMIDQLAKMLGY
QPASREVIERILSLPHDLLSSHWPTLLLSLLTLLVLLGLRRLRPGWPAALLVIILAMLLVWLGGLQRFGIQTISGLDGTL
PVVQWPNFQPALLRDLVMPSLNLALISFVSLMLTARSFASKNGYEVNPDAEFRALGVANIVSALSQGFAISGASSRTAVN
DANGGKSQLVSIVAALSIAAVLLLLGNLLRYIPVAVLGVVLVYASWLLLDIRSLVSLRKHNPSAFRLALFTFASVLLVGV
MPGIGLAVLLGLLQFFRTVFRPSEQLLGVNEEGMIHSLGNGNQVRAVEGVLIYRFNSPLTYFNIAYFKRRVLNLVDGMPF
QPEWVVIDAVSCFTYPDISVLAGIDELKRDLRQRRVHLVLAGRKTDLKRWFGRSRATGEEKGLLFVADLYLALKLIQSSR
CAHADGVDGSPGAAQNGTVAPR

Sequences:

>Translated_582_residues
MQCDFLRRGMPGLYQLTKYRREWLADDLRAGLSVAAVALPTALAYADLVGVTAVVGIYSCILPMIAYALFGSSRQVIVGP
DAATCAVIAAVVTPLAAGDPQRLWQLCVMMTLMTGLWCLVASRFRLGALADLLSRPILTGLLNGLAITIMIDQLAKMLGY
QPASREVIERILSLPHDLLSSHWPTLLLSLLTLLVLLGLRRLRPGWPAALLVIILAMLLVWLGGLQRFGIQTISGLDGTL
PVVQWPNFQPALLRDLVMPSLNLALISFVSLMLTARSFASKNGYEVNPDAEFRALGVANIVSALSQGFAISGASSRTAVN
DANGGKSQLVSIVAALSIAAVLLLLGNLLRYIPVAVLGVVLVYASWLLLDIRSLVSLRKHNPSAFRLALFTFASVLLVGV
MPGIGLAVLLGLLQFFRTVFRPSEQLLGVNEEGMIHSLGNGNQVRAVEGVLIYRFNSPLTYFNIAYFKRRVLNLVDGMPF
QPEWVVIDAVSCFTYPDISVLAGIDELKRDLRQRRVHLVLAGRKTDLKRWFGRSRATGEEKGLLFVADLYLALKLIQSSR
CAHADGVDGSPGAAQNGTVAPR
>Mature_582_residues
MQCDFLRRGMPGLYQLTKYRREWLADDLRAGLSVAAVALPTALAYADLVGVTAVVGIYSCILPMIAYALFGSSRQVIVGP
DAATCAVIAAVVTPLAAGDPQRLWQLCVMMTLMTGLWCLVASRFRLGALADLLSRPILTGLLNGLAITIMIDQLAKMLGY
QPASREVIERILSLPHDLLSSHWPTLLLSLLTLLVLLGLRRLRPGWPAALLVIILAMLLVWLGGLQRFGIQTISGLDGTL
PVVQWPNFQPALLRDLVMPSLNLALISFVSLMLTARSFASKNGYEVNPDAEFRALGVANIVSALSQGFAISGASSRTAVN
DANGGKSQLVSIVAALSIAAVLLLLGNLLRYIPVAVLGVVLVYASWLLLDIRSLVSLRKHNPSAFRLALFTFASVLLVGV
MPGIGLAVLLGLLQFFRTVFRPSEQLLGVNEEGMIHSLGNGNQVRAVEGVLIYRFNSPLTYFNIAYFKRRVLNLVDGMPF
QPEWVVIDAVSCFTYPDISVLAGIDELKRDLRQRRVHLVLAGRKTDLKRWFGRSRATGEEKGLLFVADLYLALKLIQSSR
CAHADGVDGSPGAAQNGTVAPR

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI45827800, Length=476, Percent_Identity=26.890756302521, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI39752683, Length=476, Percent_Identity=26.890756302521, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI94721259, Length=502, Percent_Identity=27.4900398406374, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI4505697, Length=511, Percent_Identity=25.2446183953033, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI94721257, Length=502, Percent_Identity=27.0916334661355, Blast_Score=142, Evalue=9e-34,
Organism=Homo sapiens, GI94721255, Length=502, Percent_Identity=27.0916334661355, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI94721253, Length=502, Percent_Identity=27.0916334661355, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI4557535, Length=512, Percent_Identity=25.5859375, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI269784651, Length=475, Percent_Identity=25.8947368421053, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI45827802, Length=431, Percent_Identity=27.3781902552204, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI47131207, Length=513, Percent_Identity=28.4600389863548, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI20336272, Length=513, Percent_Identity=28.4600389863548, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI262206105, Length=564, Percent_Identity=25, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI262206075, Length=564, Percent_Identity=25, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI262206069, Length=564, Percent_Identity=25, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI262206063, Length=564, Percent_Identity=25, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI16418413, Length=516, Percent_Identity=24.8062015503876, Blast_Score=116, Evalue=7e-26,
Organism=Homo sapiens, GI217272867, Length=521, Percent_Identity=24.3761996161228, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI16418457, Length=544, Percent_Identity=25.5514705882353, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI301601599, Length=544, Percent_Identity=25.5514705882353, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI100913030, Length=645, Percent_Identity=24.1860465116279, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI20336282, Length=646, Percent_Identity=21.2074303405573, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI16306483, Length=635, Percent_Identity=21.259842519685, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI301601602, Length=271, Percent_Identity=28.0442804428044, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI65506789, Length=349, Percent_Identity=28.3667621776504, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI87081859, Length=429, Percent_Identity=24.7086247086247, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17551690, Length=579, Percent_Identity=24.8704663212435, Blast_Score=158, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI86564196, Length=621, Percent_Identity=23.1884057971014, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI86565215, Length=486, Percent_Identity=23.8683127572016, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17566848, Length=565, Percent_Identity=24.070796460177, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17562578, Length=614, Percent_Identity=22.9641693811075, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI193203292, Length=501, Percent_Identity=24.1516966067864, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI86564876, Length=396, Percent_Identity=22.4747474747475, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI86565213, Length=173, Percent_Identity=26.5895953757225, Blast_Score=66, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6325260, Length=503, Percent_Identity=25.4473161033797, Blast_Score=116, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6323121, Length=470, Percent_Identity=23.8297872340426, Blast_Score=107, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6319771, Length=588, Percent_Identity=22.6190476190476, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21358229, Length=465, Percent_Identity=26.4516129032258, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24666186, Length=548, Percent_Identity=23.1751824817518, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24649801, Length=555, Percent_Identity=24.6846846846847, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24651449, Length=577, Percent_Identity=21.6637781629116, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI19922482, Length=529, Percent_Identity=23.2514177693762, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24647160, Length=436, Percent_Identity=23.8532110091743, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI85815873, Length=394, Percent_Identity=24.3654822335025, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21355087, Length=436, Percent_Identity=23.8532110091743, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24663084, Length=443, Percent_Identity=26.86230248307, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21357695, Length=443, Percent_Identity=26.86230248307, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21358633, Length=534, Percent_Identity=22.8464419475655, Blast_Score=96, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 63118; Mature: 63118

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure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CCEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]