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The map label for this gene is dhaL [H]

Identifier: 238919158

GI number: 238919158

Start: 1223180

End: 1223833

Strand: Direct

Name: dhaL [H]

Synonym: NT01EI_1229

Alternate gene names: 238919158

Gene position: 1223180-1223833 (Clockwise)

Preceding gene: 238919157

Following gene: 238919159

Centisome position: 32.08

GC content: 62.39

Gene sequence:

>654_bases
ATGGCTTATGCAGTCACCGTTTCCAACGGCGGAGAAATTGTCGCTGCGCTGGTCGCCGCGGTGGTCAGCCAGCGGACGTA
TCTCAGTGAAATTGACGGCGCCATCGGCGATGGTGATCACGGTGTAAATATGGCGAAGGGATTTATGCTGTGCGCTGACG
CCATGGCTGGGCAACGGCTTTCCTTGCCGCAGGCATTGCGCTGCCTATCGGAGTCGCTGATGGAGGGAATTGGCGGCTCT
ATGGGGCCGCTGTACGGCAGCCTGTTTATGGGGATGGCGCAGGGCGCGCCGGAGAGCGCTACGCTGCGTCGTGAGGACGT
GCTGTCTATGCTGCAGGGCGGACTGCGTGAGTTACAGACGGTCAGCAGCGCGCAGGTGGGAGATAAAACCATGATGGATG
CCTATGTCCCGGCGGTGTCTGCCTTTGAGGCGGCTCTGCGGCAAGGCGATAGCCTAGAGCGGTCGCTCTGCATGATGACG
CAAGCGGCGGCACGCGGACGTGACAGTACCTACGACCTCATCGCCCGAGTTGGCCGGGCTAGCCGTCTGGGGGAGCGTTC
TCGGGGCGCGTTGGATGCCGGCGCCGTATCCTGTAGCCTGCTGCTGTCGGCGTTGGCGGATGCGTTACTTGCGTGTTCCA
ACGACGGTGAGTAG

Upstream 100 bases:

>100_bases
TGGGGGTAACGCTGACGGTTATGGCGTTGGACGATGAGCTGAAATTATTACTCAATATGCCGGTGTCATCACCGGGATTG
ACGCAGGAGGGGTAATCACG

Downstream 100 bases:

>100_bases
CGGTGTTTTTTGTCAGACCATGCGATCTGCGTCTATACGATGGGATCCCCACGTGGGCTATGCTTATAGCCCACGACGGC
AGACGAGACAGGGTGTGTAG

Product: dihydroxyacetone kinase, L subunit

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MAYAVTVSNGGEIVAALVAAVVSQRTYLSEIDGAIGDGDHGVNMAKGFMLCADAMAGQRLSLPQALRCLSESLMEGIGGS
MGPLYGSLFMGMAQGAPESATLRREDVLSMLQGGLRELQTVSSAQVGDKTMMDAYVPAVSAFEAALRQGDSLERSLCMMT
QAAARGRDSTYDLIARVGRASRLGERSRGALDAGAVSCSLLLSALADALLACSNDGE

Sequences:

>Translated_217_residues
MAYAVTVSNGGEIVAALVAAVVSQRTYLSEIDGAIGDGDHGVNMAKGFMLCADAMAGQRLSLPQALRCLSESLMEGIGGS
MGPLYGSLFMGMAQGAPESATLRREDVLSMLQGGLRELQTVSSAQVGDKTMMDAYVPAVSAFEAALRQGDSLERSLCMMT
QAAARGRDSTYDLIARVGRASRLGERSRGALDAGAVSCSLLLSALADALLACSNDGE
>Mature_216_residues
AYAVTVSNGGEIVAALVAAVVSQRTYLSEIDGAIGDGDHGVNMAKGFMLCADAMAGQRLSLPQALRCLSESLMEGIGGSM
GPLYGSLFMGMAQGAPESATLRREDVLSMLQGGLRELQTVSSAQVGDKTMMDAYVPAVSAFEAALRQGDSLERSLCMMTQ
AAARGRDSTYDLIARVGRASRLGERSRGALDAGAVSCSLLLSALADALLACSNDGE

Specific function: ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain [H]

Homologues:

Organism=Escherichia coli, GI1787449, Length=187, Percent_Identity=34.2245989304813, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17565018, Length=201, Percent_Identity=30.3482587064677, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323570, Length=197, Percent_Identity=29.4416243654822, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004007
- InterPro:   IPR012737 [H]

Pfam domain/function: PF02734 Dak2 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 22438; Mature: 22307

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYAVTVSNGGEIVAALVAAVVSQRTYLSEIDGAIGDGDHGVNMAKGFMLCADAMAGQRL
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
SLPQALRCLSESLMEGIGGSMGPLYGSLFMGMAQGAPESATLRREDVLSMLQGGLRELQT
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
VSSAQVGDKTMMDAYVPAVSAFEAALRQGDSLERSLCMMTQAAARGRDSTYDLIARVGRA
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
SRLGERSRGALDAGAVSCSLLLSALADALLACSNDGE
HHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AYAVTVSNGGEIVAALVAAVVSQRTYLSEIDGAIGDGDHGVNMAKGFMLCADAMAGQRL
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
SLPQALRCLSESLMEGIGGSMGPLYGSLFMGMAQGAPESATLRREDVLSMLQGGLRELQT
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
VSSAQVGDKTMMDAYVPAVSAFEAALRQGDSLERSLCMMTQAAARGRDSTYDLIARVGRA
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
SRLGERSRGALDAGAVSCSLLLSALADALLACSNDGE
HHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]