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The map label for this gene is htpG [H]

Identifier: 238919054

GI number: 238919054

Start: 1118491

End: 1120362

Strand: Direct

Name: htpG [H]

Synonym: NT01EI_1122

Alternate gene names: 238919054

Gene position: 1118491-1120362 (Clockwise)

Preceding gene: 238919048

Following gene: 238919055

Centisome position: 29.34

GC content: 58.07

Gene sequence:

>1872_bases
ATGAAAGGCCAAGAAACCCGTGGCTTCCAGTCAGAGGTGAAACAGCTTCTGCACCTGATGATCCACTCACTCTACTCCAA
TAAAGAGATCTTCCTGCGTGAGCTTATCTCCAACGCGTCCGATGCTGCTGACAAACTGCGCTTCCGTGCGCTGTCCAACC
CGGATCTGTATCAGGGCGATGGTGAGCTGCGCGTGCGCGTCAGTGTGGATCGCGACAACCGCACCCTGACGCTGAGCGAT
AACGGCATCGGTATGACGCGCGATGAGGTAATCGAGAACCTTGGCACCATCGCTAAGTCCGGTACCAAAGCGTTCCTGGA
GTCAATGGGCTCCGATCAGGCGAAAGACAGCCAGCTTATCGGGCAGTTTGGCGTGGGCTTCTACTCCGCCTTTATCGTGG
CGGATAAGGTCACCGTCCGTACCCGCGCCGCCGGCGCCAGCGCTGATCAGGGGGTATTCTGGGAGTCTGCCGGTGAGGGC
GACTACACCATCGCCGATATCGAGAAAGCCGATCGCGGCACCGAGATCACCCTGCACCTGCGCGAGGGCGAGGATGACTT
CCTGGATGACTGGCGGCTGCGTAACATCATCGGCAAGTACTCCGACCATATCGCTCTGCCTGTCGAGATCCTCAGCAGCG
AGGGCGAAGAGGGCGAGAAGAAGTGGGAGAAGATCAATAAGGCTCAGGCGCTGTGGACCCGCAATAAAGCGGATATCAGC
GATGAAGAGTATAACGAGTTCTATAAACACATCGCCCATGACTTCAGCGATCCGCTGGCCTGGAGCCATAACCGGGTAGA
GGGCAAACAGGAGTACACCAGCCTGCTGTATATCCCCTCCAAGGCACCCTGGGATCTGTTTAACCGCGACCATCAGCACG
GTCTGAAGCTGTATGTGCAGCGCGTGTTCATCATGGACGACGCCGAGCAGTTTATGCCGAACTACCTGCGCTTTGTGCGT
GGCCTGGTGGACTCTAACGATCTGCCACTCAACGTTTCGCGTGAGCTGTTGCAGGATAGTCGCGTCACTCAGAACCTGCG
TTCAGCGCTGACCAAGCGCGTGCTACAGATGCTGGAAAAACTGGCCAAGGATGATGCCGAAGCCTATCAGACCTTCTGGC
AACAATTCGGCCTGGTGCTGAAAGAGGGGCCGGCGGAGGATGCTGCCAACCGTGAAGCGATTGCCAAACTGTTGCGCTTT
GCTTCCACCCATAATGACAGCGCATTGCAAAACGTGTCGCTGGACGACTACATCGGGCGCATGAAGGAAGGGCAGGAGAA
GATTTACTACATCACCGCCGACAGCTATGCCGCCGCTGCCAGCAGCCCGCATCTGGAGCTGCTGCGTAAGAAGGGCATCG
AAGTACTGCTGCTCTCCGAGCGTATCGATGAGTGGATGATGAGCTACCTGACCGAGTACGATGCCAAGTCCTTCCAGTCT
GTCAGTAAGAAGGATGAGACGCTGGAGAAACTGGCCGACGAAGGGGACAGCGATGCGCAGAAAGAGGCGGATAAAGCGCT
GGAGCCGTTCGTTGAGCGGGTGAAAACCCTGCTGGGCGAGCGGGTGAAGGCGGTACGCCTGACGCATCGCCTGACCGATA
CGCCGGCGGTGGTCAGCACCGACGGCGATGAGATGACGACCCAGATGGCCAAGTTGTTTGCCGCCGCGGGACAGCAGGCG
CCGGAAGTGAAGTATATCTTCGAACTCAATCCGGAGCATGCGCTGGTACAGCGCGCTGCGGAGTTGCAGGATGACGGGCG
CTTTGCCCAGTGGATTGAGCTGCTGCTGGATCAGGCTCTGCTCGCCGAGCGCGGCAGCCTGGAAGATCCTAACCAGTTCA
TCAAGCGTATCAACACGCTGCTGCTGGCCTGA

Upstream 100 bases:

>100_bases
TATCTGTTTTGTTACCCTTGAAAAGCGAATTTGTGGTCCCCATCTGTAACGCTATAACCCATTTTATCTGCGTGTTATCG
ATGAGAGGTAAAAGCGAATA

Downstream 100 bases:

>100_bases
TAGCCGGTCATTGCGTGAAAGGGCGGCCTCTGGGCCGCCCTTTCTGTTTGGCCGCTGCCCGACGGAAAGCGGGTTTTTTA
CCGGCAATTGCGTCGAACGA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 623; Mature: 623

Protein sequence:

>623_residues
MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYQGDGELRVRVSVDRDNRTLTLSD
NGIGMTRDEVIENLGTIAKSGTKAFLESMGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGASADQGVFWESAGEG
DYTIADIEKADRGTEITLHLREGEDDFLDDWRLRNIIGKYSDHIALPVEILSSEGEEGEKKWEKINKAQALWTRNKADIS
DEEYNEFYKHIAHDFSDPLAWSHNRVEGKQEYTSLLYIPSKAPWDLFNRDHQHGLKLYVQRVFIMDDAEQFMPNYLRFVR
GLVDSNDLPLNVSRELLQDSRVTQNLRSALTKRVLQMLEKLAKDDAEAYQTFWQQFGLVLKEGPAEDAANREAIAKLLRF
ASTHNDSALQNVSLDDYIGRMKEGQEKIYYITADSYAAAASSPHLELLRKKGIEVLLLSERIDEWMMSYLTEYDAKSFQS
VSKKDETLEKLADEGDSDAQKEADKALEPFVERVKTLLGERVKAVRLTHRLTDTPAVVSTDGDEMTTQMAKLFAAAGQQA
PEVKYIFELNPEHALVQRAAELQDDGRFAQWIELLLDQALLAERGSLEDPNQFIKRINTLLLA

Sequences:

>Translated_623_residues
MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYQGDGELRVRVSVDRDNRTLTLSD
NGIGMTRDEVIENLGTIAKSGTKAFLESMGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGASADQGVFWESAGEG
DYTIADIEKADRGTEITLHLREGEDDFLDDWRLRNIIGKYSDHIALPVEILSSEGEEGEKKWEKINKAQALWTRNKADIS
DEEYNEFYKHIAHDFSDPLAWSHNRVEGKQEYTSLLYIPSKAPWDLFNRDHQHGLKLYVQRVFIMDDAEQFMPNYLRFVR
GLVDSNDLPLNVSRELLQDSRVTQNLRSALTKRVLQMLEKLAKDDAEAYQTFWQQFGLVLKEGPAEDAANREAIAKLLRF
ASTHNDSALQNVSLDDYIGRMKEGQEKIYYITADSYAAAASSPHLELLRKKGIEVLLLSERIDEWMMSYLTEYDAKSFQS
VSKKDETLEKLADEGDSDAQKEADKALEPFVERVKTLLGERVKAVRLTHRLTDTPAVVSTDGDEMTTQMAKLFAAAGQQA
PEVKYIFELNPEHALVQRAAELQDDGRFAQWIELLLDQALLAERGSLEDPNQFIKRINTLLLA
>Mature_623_residues
MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYQGDGELRVRVSVDRDNRTLTLSD
NGIGMTRDEVIENLGTIAKSGTKAFLESMGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGASADQGVFWESAGEG
DYTIADIEKADRGTEITLHLREGEDDFLDDWRLRNIIGKYSDHIALPVEILSSEGEEGEKKWEKINKAQALWTRNKADIS
DEEYNEFYKHIAHDFSDPLAWSHNRVEGKQEYTSLLYIPSKAPWDLFNRDHQHGLKLYVQRVFIMDDAEQFMPNYLRFVR
GLVDSNDLPLNVSRELLQDSRVTQNLRSALTKRVLQMLEKLAKDDAEAYQTFWQQFGLVLKEGPAEDAANREAIAKLLRF
ASTHNDSALQNVSLDDYIGRMKEGQEKIYYITADSYAAAASSPHLELLRKKGIEVLLLSERIDEWMMSYLTEYDAKSFQS
VSKKDETLEKLADEGDSDAQKEADKALEPFVERVKTLLGERVKAVRLTHRLTDTPAVVSTDGDEMTTQMAKLFAAAGQQA
PEVKYIFELNPEHALVQRAAELQDDGRFAQWIELLLDQALLAERGSLEDPNQFIKRINTLLLA

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI4507677, Length=682, Percent_Identity=37.0967741935484, Blast_Score=418, Evalue=1e-117,
Organism=Homo sapiens, GI155722983, Length=630, Percent_Identity=35.2380952380952, Blast_Score=380, Evalue=1e-105,
Organism=Homo sapiens, GI154146191, Length=410, Percent_Identity=38.780487804878, Blast_Score=281, Evalue=2e-75,
Organism=Homo sapiens, GI153792590, Length=410, Percent_Identity=38.5365853658537, Blast_Score=278, Evalue=8e-75,
Organism=Homo sapiens, GI20149594, Length=410, Percent_Identity=37.8048780487805, Blast_Score=272, Evalue=7e-73,
Organism=Escherichia coli, GI1786679, Length=625, Percent_Identity=83.84, Blast_Score=1095, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=668, Percent_Identity=37.4251497005988, Blast_Score=458, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI17542208, Length=676, Percent_Identity=37.8698224852071, Blast_Score=411, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI115535205, Length=636, Percent_Identity=33.8050314465409, Blast_Score=334, Evalue=8e-92,
Organism=Caenorhabditis elegans, GI115535167, Length=421, Percent_Identity=37.29216152019, Blast_Score=277, Evalue=1e-74,
Organism=Saccharomyces cerevisiae, GI6323840, Length=676, Percent_Identity=37.7218934911243, Blast_Score=456, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6325016, Length=682, Percent_Identity=36.950146627566, Blast_Score=453, Evalue=1e-128,
Organism=Drosophila melanogaster, GI21357739, Length=629, Percent_Identity=38.79173290938, Blast_Score=403, Evalue=1e-112,
Organism=Drosophila melanogaster, GI24586016, Length=636, Percent_Identity=37.1069182389937, Blast_Score=384, Evalue=1e-107,
Organism=Drosophila melanogaster, GI17647529, Length=410, Percent_Identity=37.0731707317073, Blast_Score=280, Evalue=2e-75,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 70624; Mature: 70624

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYQGD
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCC
GELRVRVSVDRDNRTLTLSDNGIGMTRDEVIENLGTIAKSGTKAFLESMGSDQAKDSQLI
CCEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHH
GQFGVGFYSAFIVADKVTVRTRAAGASADQGVFWESAGEGDYTIADIEKADRGTEITLHL
HHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEECCCCCCCEEEEECHHCCCCCEEEEEE
REGEDDFLDDWRLRNIIGKYSDHIALPVEILSSEGEEGEKKWEKINKAQALWTRNKADIS
ECCCCHHHHHHHHHHHHHHHCCCCEEHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
DEEYNEFYKHIAHDFSDPLAWSHNRVEGKQEYTSLLYIPSKAPWDLFNRDHQHGLKLYVQ
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCEEEECCCCCCHHHHCCCHHHHHHHHHH
RVFIMDDAEQFMPNYLRFVRGLVDSNDLPLNVSRELLQDSRVTQNLRSALTKRVLQMLEK
HHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAKDDAEAYQTFWQQFGLVLKEGPAEDAANREAIAKLLRFASTHNDSALQNVSLDDYIGR
HHHCHHHHHHHHHHHHCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHCCCHHHHHHH
MKEGQEKIYYITADSYAAAASSPHLELLRKKGIEVLLLSERIDEWMMSYLTEYDAKSFQS
HHCCCCEEEEEEECCHHHHCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
VSKKDETLEKLADEGDSDAQKEADKALEPFVERVKTLLGERVKAVRLTHRLTDTPAVVST
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
DGDEMTTQMAKLFAAAGQQAPEVKYIFELNPEHALVQRAAELQDDGRFAQWIELLLDQAL
CCHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LAERGSLEDPNQFIKRINTLLLA
HHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYQGD
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCC
GELRVRVSVDRDNRTLTLSDNGIGMTRDEVIENLGTIAKSGTKAFLESMGSDQAKDSQLI
CCEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHH
GQFGVGFYSAFIVADKVTVRTRAAGASADQGVFWESAGEGDYTIADIEKADRGTEITLHL
HHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEECCCCCCCEEEEECHHCCCCCEEEEEE
REGEDDFLDDWRLRNIIGKYSDHIALPVEILSSEGEEGEKKWEKINKAQALWTRNKADIS
ECCCCHHHHHHHHHHHHHHHCCCCEEHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
DEEYNEFYKHIAHDFSDPLAWSHNRVEGKQEYTSLLYIPSKAPWDLFNRDHQHGLKLYVQ
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCEEEECCCCCCHHHHCCCHHHHHHHHHH
RVFIMDDAEQFMPNYLRFVRGLVDSNDLPLNVSRELLQDSRVTQNLRSALTKRVLQMLEK
HHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAKDDAEAYQTFWQQFGLVLKEGPAEDAANREAIAKLLRFASTHNDSALQNVSLDDYIGR
HHHCHHHHHHHHHHHHCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHCCCHHHHHHH
MKEGQEKIYYITADSYAAAASSPHLELLRKKGIEVLLLSERIDEWMMSYLTEYDAKSFQS
HHCCCCEEEEEEECCHHHHCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
VSKKDETLEKLADEGDSDAQKEADKALEPFVERVKTLLGERVKAVRLTHRLTDTPAVVST
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
DGDEMTTQMAKLFAAAGQQAPEVKYIFELNPEHALVQRAAELQDDGRFAQWIELLLDQAL
CCHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LAERGSLEDPNQFIKRINTLLLA
HHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA