Click here to switch to the map view.

The map label for this gene is mepA [H]

Identifier: 238917414

GI number: 238917414

Start: 1547665

End: 1548999

Strand: Reverse

Name: mepA [H]

Synonym: EUBELI_01492

Alternate gene names: 238917414

Gene position: 1548999-1547665 (Counterclockwise)

Preceding gene: 238917415

Following gene: 238917413

Centisome position: 72.24

GC content: 38.73

Gene sequence:

>1335_bases
ATGAAAGAAGAGATTAAATTATCAGATCATTTTGGATATAGGAAACTCATGAGATTCACAATGCCATCAATTGTTATGCT
GATATTTACATCTATATATGGCGTTGTTGATGGCTTGTTTGTTTCTAACTTTGTAGGTAAAACTTCATTTGCAGCAGTTA
ATCTGATTATGCCGGTGCTTATGATTCTTGGCTGCGTCGGATTTATGTTTGGAACAGGTGGTGGCGCACTTATTGCAATG
TCACTTGGAGAGGGAAAGAAAGAGAAGGCAAGCCACATATTCTCGTTTATAGTGGCATTTTCAGCAATATGCGGTATTGT
ATTAGGACTTCTTGGTATTATATTGATAAGACCTGTTGCCATGATGCTTGGTGCAGAAGGAAAGCTTCTTAGTGACTGTG
TATTATATGGAAGAATTATTCTTGCGGCATTACCTTTTTATATATTGCAGTTTGAGTTTCAGTGTCTGTTTGCAACAGCG
GGAAAGCCTAAGCTTGGTCTGTATGTGACTGTGGCAGCAGGTGTTACCAATATGGCGCTTGATGCACTTTTTGTTGCAGG
ATTCAGATGGGGGCTTGTCGGTGCGGCACTTGCAACTTCGATGAGTGAGCTTGTTGGAGGTGCAATTCCGGTTGTGTATT
TTATGAAAAAGAACACAAGCCTTTTAAGATTAACAAAGTTCAGATTTGATATCAGAATACTTGGTAAAGCAGCATCTAAC
GGTGCGTCTGAATTCATGAATAATGTGTCAGCGTCTTTAGTAAGTATGCTTTACAATATGCAGTTGATGAAATATGCCGG
AGAAAATGGAATTGCAGCTTATGGTGTTGTTATGTATGTCAATTTCATATTTCAGGCAATATTCATGGGATACTCAGTAG
GAAGTGCACCTATTGTCGGATTTAATTATGGCTCTGGTAATAAAAAAGAATTAAAGAGTATTCTTGGAAAAGGTATAAGA
ATTATCGTTGTTGGAGCATTTACAATGTTTGTGCTGGGACAGGTTCTTGCAAGACCGCTTGCGCAGGTGTTTGTCGGGTA
TGATAAGGAATTATTCGACATAACTGTTGCAGGTTTCATGATTTTTTCATGTTCGTTTCTGTTTTCAGGCTTCCCGATAT
TAGGTTCGTCATTCTTCACAGCACTTAGTGATGGCCTTACATCAGCATTGATATCGTTTCTTAGGACCCTTGTATTTCAG
GTGACAGCAGTGCTTATTCTGCCTGTGTTTTTCAAGCTTACAGGTGTGTGGATGTCAGTAGTTGTGGCAGAATTTCTTGC
TATGATTGCAACCATAATTTTCCTTGTTGCGAAGAAGAAAAAATATGGGTATTAA

Upstream 100 bases:

>100_bases
ATGCATTAAGCCATGCGGCAGGAAAGAGATTTTACGAGCTTCCTATAACTCCTGACCAGATTGCAATGGCAAGACAGAAG
TGATTATTTTGAGGAAATGA

Downstream 100 bases:

>100_bases
GTACTAAAAGCGATTGACCGCAATGCTTAGTGATGATAGAATTATTTCTTATAATATGACAGATAATTTACTTACGAAAG
GAATCATTACTATGAATTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MKEEIKLSDHFGYRKLMRFTMPSIVMLIFTSIYGVVDGLFVSNFVGKTSFAAVNLIMPVLMILGCVGFMFGTGGGALIAM
SLGEGKKEKASHIFSFIVAFSAICGIVLGLLGIILIRPVAMMLGAEGKLLSDCVLYGRIILAALPFYILQFEFQCLFATA
GKPKLGLYVTVAAGVTNMALDALFVAGFRWGLVGAALATSMSELVGGAIPVVYFMKKNTSLLRLTKFRFDIRILGKAASN
GASEFMNNVSASLVSMLYNMQLMKYAGENGIAAYGVVMYVNFIFQAIFMGYSVGSAPIVGFNYGSGNKKELKSILGKGIR
IIVVGAFTMFVLGQVLARPLAQVFVGYDKELFDITVAGFMIFSCSFLFSGFPILGSSFFTALSDGLTSALISFLRTLVFQ
VTAVLILPVFFKLTGVWMSVVVAEFLAMIATIIFLVAKKKKYGY

Sequences:

>Translated_444_residues
MKEEIKLSDHFGYRKLMRFTMPSIVMLIFTSIYGVVDGLFVSNFVGKTSFAAVNLIMPVLMILGCVGFMFGTGGGALIAM
SLGEGKKEKASHIFSFIVAFSAICGIVLGLLGIILIRPVAMMLGAEGKLLSDCVLYGRIILAALPFYILQFEFQCLFATA
GKPKLGLYVTVAAGVTNMALDALFVAGFRWGLVGAALATSMSELVGGAIPVVYFMKKNTSLLRLTKFRFDIRILGKAASN
GASEFMNNVSASLVSMLYNMQLMKYAGENGIAAYGVVMYVNFIFQAIFMGYSVGSAPIVGFNYGSGNKKELKSILGKGIR
IIVVGAFTMFVLGQVLARPLAQVFVGYDKELFDITVAGFMIFSCSFLFSGFPILGSSFFTALSDGLTSALISFLRTLVFQ
VTAVLILPVFFKLTGVWMSVVVAEFLAMIATIIFLVAKKKKYGY
>Mature_444_residues
MKEEIKLSDHFGYRKLMRFTMPSIVMLIFTSIYGVVDGLFVSNFVGKTSFAAVNLIMPVLMILGCVGFMFGTGGGALIAM
SLGEGKKEKASHIFSFIVAFSAICGIVLGLLGIILIRPVAMMLGAEGKLLSDCVLYGRIILAALPFYILQFEFQCLFATA
GKPKLGLYVTVAAGVTNMALDALFVAGFRWGLVGAALATSMSELVGGAIPVVYFMKKNTSLLRLTKFRFDIRILGKAASN
GASEFMNNVSASLVSMLYNMQLMKYAGENGIAAYGVVMYVNFIFQAIFMGYSVGSAPIVGFNYGSGNKKELKSILGKGIR
IIVVGAFTMFVLGQVLARPLAQVFVGYDKELFDITVAGFMIFSCSFLFSGFPILGSSFFTALSDGLTSALISFLRTLVFQ
VTAVLILPVFFKLTGVWMSVVVAEFLAMIATIIFLVAKKKKYGY

Specific function: Multidrug resistance efflux protein [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 47977; Mature: 47977

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEEIKLSDHFGYRKLMRFTMPSIVMLIFTSIYGVVDGLFVSNFVGKTSFAAVNLIMPVL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
MILGCVGFMFGTGGGALIAMSLGEGKKEKASHIFSFIVAFSAICGIVLGLLGIILIRPVA
HHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MMLGAEGKLLSDCVLYGRIILAALPFYILQFEFQCLFATAGKPKLGLYVTVAAGVTNMAL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEEEHHCHHHHHH
DALFVAGFRWGLVGAALATSMSELVGGAIPVVYFMKKNTSLLRLTKFRFDIRILGKAASN
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEECCCCHHHHHHHHHHHHEECCHHCC
GASEFMNNVSASLVSMLYNMQLMKYAGENGIAAYGVVMYVNFIFQAIFMGYSVGSAPIVG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
FNYGSGNKKELKSILGKGIRIIVVGAFTMFVLGQVLARPLAQVFVGYDKELFDITVAGFM
EECCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IFSCSFLFSGFPILGSSFFTALSDGLTSALISFLRTLVFQVTAVLILPVFFKLTGVWMSV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVAEFLAMIATIIFLVAKKKKYGY
HHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKEEIKLSDHFGYRKLMRFTMPSIVMLIFTSIYGVVDGLFVSNFVGKTSFAAVNLIMPVL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
MILGCVGFMFGTGGGALIAMSLGEGKKEKASHIFSFIVAFSAICGIVLGLLGIILIRPVA
HHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MMLGAEGKLLSDCVLYGRIILAALPFYILQFEFQCLFATAGKPKLGLYVTVAAGVTNMAL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEEEHHCHHHHHH
DALFVAGFRWGLVGAALATSMSELVGGAIPVVYFMKKNTSLLRLTKFRFDIRILGKAASN
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEECCCCHHHHHHHHHHHHEECCHHCC
GASEFMNNVSASLVSMLYNMQLMKYAGENGIAAYGVVMYVNFIFQAIFMGYSVGSAPIVG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
FNYGSGNKKELKSILGKGIRIIVVGAFTMFVLGQVLARPLAQVFVGYDKELFDITVAGFM
EECCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IFSCSFLFSGFPILGSSFFTALSDGLTSALISFLRTLVFQVTAVLILPVFFKLTGVWMSV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVAEFLAMIATIIFLVAKKKKYGY
HHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA