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The map label for this gene is xpt [H]

Identifier: 238917413

GI number: 238917413

Start: 1546992

End: 1547642

Strand: Reverse

Name: xpt [H]

Synonym: EUBELI_01491

Alternate gene names: 238917413

Gene position: 1547642-1546992 (Counterclockwise)

Preceding gene: 238917414

Following gene: 238917412

Centisome position: 72.18

GC content: 36.71

Gene sequence:

>651_bases
ATGCTTAGTGATGATAGAATTATTTCTTATAATATGACAGATAATTTACTTACGAAAGGAATCATTACTATGAATTTTCT
TGAAGAAAGAATTATGAAGGACGGAGTTGTCAAAGAAGGCAACATTCTTAAAGTAGACAGTTTTCTTAATCATCAGATGG
ATGTTAAGCTTTTCAAGCAGATGGGCGAAGAATTTAAGAGAAGATTTGCCGGAAAGAATATTAATAAGATTATAACAATT
GAGGCTTCAGGAATTGGTATTGCATGTATAGTTGCAGAATGCTTTGATGTACCGGTTGTATTTGCAAAGAAGTCACAGAG
TGTCAATATTGATGGTGATGTGTATTCTGCGGAAGTTGAATCATTTACACATAAGTGCAAGAATCAGGTTCTTATATCTA
AGAAGTTTGTAGGTCCAGAGGATCATGTACTTATTATTGATGATTTTCTTGCAAATGGCTGTGCACTTCAGGGACTTATA
TCTATTGTCAATCAGGCAGGCGGAACTGTTGAAGGTATTGGAATCGCAGTTGAGAAGGGCTTCCAGCAGGGAGGACAGAT
TATCCGTAACCTTGGATACCAGCTGGAATCTCTGGCTATTGTTGATGGAATGAATGCTGCAGATGGCAGTATTAATTTCA
GAGAGGAGTAA

Upstream 100 bases:

>100_bases
GTAGTTGTGGCAGAATTTCTTGCTATGATTGCAACCATAATTTTCCTTGTTGCGAAGAAGAAAAAATATGGGTATTAAGT
ACTAAAAGCGATTGACCGCA

Downstream 100 bases:

>100_bases
TCATGAATGAATATCAGTTTTTTTCACCAGTAGATGTCGTATTTGGATGCGGAAGTCTTTCTAAGCTTCATACTCTTAAG
ATGCCAGGAAAGAAAGCACT

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MLSDDRIISYNMTDNLLTKGIITMNFLEERIMKDGVVKEGNILKVDSFLNHQMDVKLFKQMGEEFKRRFAGKNINKIITI
EASGIGIACIVAECFDVPVVFAKKSQSVNIDGDVYSAEVESFTHKCKNQVLISKKFVGPEDHVLIIDDFLANGCALQGLI
SIVNQAGGTVEGIGIAVEKGFQQGGQIIRNLGYQLESLAIVDGMNAADGSINFREE

Sequences:

>Translated_216_residues
MLSDDRIISYNMTDNLLTKGIITMNFLEERIMKDGVVKEGNILKVDSFLNHQMDVKLFKQMGEEFKRRFAGKNINKIITI
EASGIGIACIVAECFDVPVVFAKKSQSVNIDGDVYSAEVESFTHKCKNQVLISKKFVGPEDHVLIIDDFLANGCALQGLI
SIVNQAGGTVEGIGIAVEKGFQQGGQIIRNLGYQLESLAIVDGMNAADGSINFREE
>Mature_216_residues
MLSDDRIISYNMTDNLLTKGIITMNFLEERIMKDGVVKEGNILKVDSFLNHQMDVKLFKQMGEEFKRRFAGKNINKIITI
EASGIGIACIVAECFDVPVVFAKKSQSVNIDGDVYSAEVESFTHKCKNQVLISKKFVGPEDHVLIIDDFLANGCALQGLI
SIVNQAGGTVEGIGIAVEKGFQQGGQIIRNLGYQLESLAIVDGMNAADGSINFREE

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XPT subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR010079 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 23710; Mature: 23710

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSDDRIISYNMTDNLLTKGIITMNFLEERIMKDGVVKEGNILKVDSFLNHQMDVKLFKQ
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHCCCHHHHHHHH
MGEEFKRRFAGKNINKIITIEASGIGIACIVAECFDVPVVFAKKSQSVNIDGDVYSAEVE
HHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHCCCEEEECCCCCEECCCCCHHHHHH
SFTHKCKNQVLISKKFVGPEDHVLIIDDFLANGCALQGLISIVNQAGGTVEGIGIAVEKG
HHHHHHHHCEEEEEECCCCCCCEEEEEHHHCCCHHHHHHHHHHHHCCCCEEEEHHHHHHH
FQQGGQIIRNLGYQLESLAIVDGMNAADGSINFREE
HHHHHHHHHHHCCHHHHEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MLSDDRIISYNMTDNLLTKGIITMNFLEERIMKDGVVKEGNILKVDSFLNHQMDVKLFKQ
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHCCCHHHHHHHH
MGEEFKRRFAGKNINKIITIEASGIGIACIVAECFDVPVVFAKKSQSVNIDGDVYSAEVE
HHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHCCCEEEECCCCCEECCCCCHHHHHH
SFTHKCKNQVLISKKFVGPEDHVLIIDDFLANGCALQGLISIVNQAGGTVEGIGIAVEKG
HHHHHHHHCEEEEEECCCCCCCEEEEEHHHCCCHHHHHHHHHHHHCCCCEEEEHHHHHHH
FQQGGQIIRNLGYQLESLAIVDGMNAADGSINFREE
HHHHHHHHHHHCCHHHHEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA